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Needle Guide Friction Reduction Utilizing Contact Surface Structure.
Pub Date : 2024-01-01 Epub Date: 2024-06-25
Isaac Elijah, Sang-Eun Song

Prostate cancer ranks as the second most common cause of cancer-related mortality among males. A template guided core biopsy procedure is an essential component of prostate cancer diagnosis. Various factors influence the quality of the histological sample that is produced from the biopsy, including tissue fragmentation, needle insertion speed, needle deflection, and sheath cutting speed. In instances where a biopsy core fails to meet established clinical standards, an additional core extraction is necessary, resulting in heightened patient discomfort and an increased risk of infection. The objective of this study is to examine alternative configurations for the needle guide in order to optimize for the reduction of needle guide frictional forces while providing adequate guidance towards a target. A simulation of this interaction using different configurations of the needle guide was designed using SIMULA Abaqus, and a Finite Element Analysis was performed to observe the friction force between the needle and guide. The results showed that configurations with contact points oriented parallel to the direction of insertion exhibited the least recorded frictional forces. The study demonstrated that configurations which provided decreased contact surface compared to the control needle guide resulted in lower friction force. These findings advocate for the optimization of the conventional biopsy needle guide to reduce the contact area between the needle and guide inner surface, potentially reducing the number of passes required to obtain a histologically viable core specimen and mitigating the risk of patient infection.

前列腺癌是导致男性癌症相关死亡的第二大常见病因。模板引导的核心活检程序是前列腺癌诊断的重要组成部分。影响活检组织学样本质量的因素有很多,包括组织碎裂、穿刺针插入速度、穿刺针偏转和针鞘切割速度。如果活检样本不能达到既定的临床标准,就需要进行额外的样本提取,这会增加患者的不适感和感染风险。本研究的目的是检查针导的替代配置,以优化减少针导的摩擦力,同时为目标提供足够的引导。我们使用 SIMULA Abaqus 设计了不同配置的导针器,对这种相互作用进行了模拟,并进行了有限元分析,以观察针和导针器之间的摩擦力。结果表明,接触点平行于插入方向的配置所产生的摩擦力最小。研究表明,与对照针导向器相比,接触面较小的配置可降低摩擦力。这些研究结果主张对传统活检针导向器进行优化,以减少活检针与导向器内表面之间的接触面积,从而减少获得组织学上可行的核心标本所需的穿刺次数,降低患者感染的风险。
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引用次数: 0
IDH1 Mutations in Glioma: Considerations for Radiotracer Development. 胶质瘤中的IDH1突变:放射性示踪剂开发的考虑。
Pub Date : 2016-01-01 Epub Date: 2016-03-26
Satish K Chitneni
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引用次数: 0
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SM radiology journal
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