Pub Date : 2021-10-22DOI: 10.1002/9781119769897.ch3
I. Shurygina, I. Trukhan, N. Dremina, M. Shurygin
{"title":"Selenium Nanoparticles","authors":"I. Shurygina, I. Trukhan, N. Dremina, M. Shurygin","doi":"10.1002/9781119769897.ch3","DOIUrl":"https://doi.org/10.1002/9781119769897.ch3","url":null,"abstract":"","PeriodicalId":92383,"journal":{"name":"International journal of nanotechnology in medicine & engineering","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82496586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-10-22DOI: 10.1002/9781119769897.ch2
P. Marcelino, Fernanda Gonçalves, N. Aizawa, Henrique Paiva Pereira, T. Lacerda, S. S. Silva
{"title":"Microbial Biopolymers and Their Derivatives as Nanotechnological Tools for Medicine","authors":"P. Marcelino, Fernanda Gonçalves, N. Aizawa, Henrique Paiva Pereira, T. Lacerda, S. S. Silva","doi":"10.1002/9781119769897.ch2","DOIUrl":"https://doi.org/10.1002/9781119769897.ch2","url":null,"abstract":"","PeriodicalId":92383,"journal":{"name":"International journal of nanotechnology in medicine & engineering","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85442738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-10-22DOI: 10.1002/9781119769897.ch11
M. Chaud, F. Batain, E. Souto, P. Severino, A. Zielińska, T. Alves
{"title":"Risk Assessment of Injectable Nanoparticles Used as Nanomedicine","authors":"M. Chaud, F. Batain, E. Souto, P. Severino, A. Zielińska, T. Alves","doi":"10.1002/9781119769897.ch11","DOIUrl":"https://doi.org/10.1002/9781119769897.ch11","url":null,"abstract":"","PeriodicalId":92383,"journal":{"name":"International journal of nanotechnology in medicine & engineering","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86341004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-22DOI: 10.1007/978-3-030-61021-0_1
S. Ghouse, I. Pugazhenthi
{"title":"Nanomedicine: General Introduction from A to Z","authors":"S. Ghouse, I. Pugazhenthi","doi":"10.1007/978-3-030-61021-0_1","DOIUrl":"https://doi.org/10.1007/978-3-030-61021-0_1","url":null,"abstract":"","PeriodicalId":92383,"journal":{"name":"International journal of nanotechnology in medicine & engineering","volume":"35 1","pages":"1 - 15"},"PeriodicalIF":0.0,"publicationDate":"2021-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77693487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-22DOI: 10.1007/978-3-030-61021-0_2
Kaushita Banerjee, H. Madhyastha
{"title":"Immunology and Nanotechnology: Effects and Affects","authors":"Kaushita Banerjee, H. Madhyastha","doi":"10.1007/978-3-030-61021-0_2","DOIUrl":"https://doi.org/10.1007/978-3-030-61021-0_2","url":null,"abstract":"","PeriodicalId":92383,"journal":{"name":"International journal of nanotechnology in medicine & engineering","volume":"158 1","pages":"17 - 34"},"PeriodicalIF":0.0,"publicationDate":"2021-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86989629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.1007/978-3-030-61021-0
{"title":"Nanotechnology in Medicine","authors":"","doi":"10.1007/978-3-030-61021-0","DOIUrl":"https://doi.org/10.1007/978-3-030-61021-0","url":null,"abstract":"","PeriodicalId":92383,"journal":{"name":"International journal of nanotechnology in medicine & engineering","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87836907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christina Wilson, Bailey Brigham, Jasmin Sandoval, Derek Sabatka, Erin Wilson, Carli Sebest, Brett J Schofield, Andrea E Holmes, Arin L Sutlief
Slippery, porous polymeric antimicrobial surfaces for biofilm attachment inhibition of the clinical strain Pseudomonas aeruginosa (PA14) have been prepared. Porous BMA-EDMA, characterized for its hydrophobic properties, was infused with a slippery liquid creating a hydrophobic liquid interface and characterized by water contact angle and SEM. A low shear force bioreactor was used to prepare biofilms on these antimicrobial surfaces. Biofilm attachment was studied using fluorescence microscopy coupled with image analysis in ImageJ. While the literature presents that these slippery polymers work well as antimicrobial surfaces for several strains of Pseudomonas aeruginosa, it has been found to be strain dependent. This report demonstrates that slippery surfaces do not work well for the strain PA14, and biofilm covered >3.5 times more area as compared to the control glass surfaces.
{"title":"The Quantitative Assessment of <i>Pseudomonas aeruginosa</i> (PA)14 Biofilm Surface Coverage on Slippery Liquid Infused Polymer Surfaces (SLIPS).","authors":"Christina Wilson, Bailey Brigham, Jasmin Sandoval, Derek Sabatka, Erin Wilson, Carli Sebest, Brett J Schofield, Andrea E Holmes, Arin L Sutlief","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Slippery, porous polymeric antimicrobial surfaces for biofilm attachment inhibition of the clinical strain <i>Pseudomonas aeruginosa</i> (PA14) have been prepared. Porous BMA-EDMA, characterized for its hydrophobic properties, was infused with a slippery liquid creating a hydrophobic liquid interface and characterized by water contact angle and SEM. A low shear force bioreactor was used to prepare biofilms on these antimicrobial surfaces. Biofilm attachment was studied using fluorescence microscopy coupled with image analysis in ImageJ. While the literature presents that these slippery polymers work well as antimicrobial surfaces for several strains of <i>Pseudomonas aeruginosa</i>, it has been found to be strain dependent. This report demonstrates that slippery surfaces do not work well for the strain PA14, and biofilm covered >3.5 times more area as compared to the control glass surfaces.</p>","PeriodicalId":92383,"journal":{"name":"International journal of nanotechnology in medicine & engineering","volume":"3 3","pages":"35-42"},"PeriodicalIF":0.0,"publicationDate":"2018-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/18/9d/nihms-1006406.PMC6939446.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37508353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-12-01Epub Date: 2016-12-05DOI: 10.25141/2474-8811-2016-3.0063
Sudhakar Agnihothram, Lisa Mullis, Todd A Townsend, Fumiya Watanabe, Thikra Mustafa, Alexandru Biris, Mugimane G Manjanatha, Marli P Azevedo
Noroviruses (NoV) have enhanced tropism for the gastrointestinal (GI) tract and are the major cause of nonbacterial gastroenteritis in humans. Titanium dioxide (TiO2) nanoparticles (NPs) used as food additives, dietary supplements, and cosmetics accumulate in the GI tract. We investigated the effect anatase TiO2 NPs on NoV replication and host response during virus infection, using murine norovirus (MNV-1) infection of RAW 264.7 macrophages. Pretreatment with 20 μg/ml anatase NPs significantly reduced the viability of macrophages alone or during virus infection, but did not alter virus replication. In contrast, pre-incubation with 2 μg/ml anatase NPs reduced virus replication fivefold at 48 h. The presence of anatase NPs during MNV-1 infection evoked a pro-inflammatory response, as measured by a significant increase in expression of cytokines, including IL-6, IFN-γ, TNFα and the TGFβ1. No genotoxic insults due to anatase TiO2 NPs alone or to their presence during MNV-1 infection were detected. This study highlights important safety considerations related to NP exposure of the GI tract in individuals infected with noroviruses or other foodborne viruses.
{"title":"Titanium Dioxide Nanoparticles Evoke Proinflammatory Response during Murine Norovirus Infection Despite Having Minimal Effects on Virus Replication.","authors":"Sudhakar Agnihothram, Lisa Mullis, Todd A Townsend, Fumiya Watanabe, Thikra Mustafa, Alexandru Biris, Mugimane G Manjanatha, Marli P Azevedo","doi":"10.25141/2474-8811-2016-3.0063","DOIUrl":"https://doi.org/10.25141/2474-8811-2016-3.0063","url":null,"abstract":"<p><p>Noroviruses (NoV) have enhanced tropism for the gastrointestinal (GI) tract and are the major cause of nonbacterial gastroenteritis in humans. Titanium dioxide (TiO2) nanoparticles (NPs) used as food additives, dietary supplements, and cosmetics accumulate in the GI tract. We investigated the effect anatase TiO2 NPs on NoV replication and host response during virus infection, using murine norovirus (MNV-1) infection of RAW 264.7 macrophages. Pretreatment with 20 μg/ml anatase NPs significantly reduced the viability of macrophages alone or during virus infection, but did not alter virus replication. In contrast, pre-incubation with 2 μg/ml anatase NPs reduced virus replication fivefold at 48 h. The presence of anatase NPs during MNV-1 infection evoked a pro-inflammatory response, as measured by a significant increase in expression of cytokines, including IL-6, IFN-γ, TNFα and the TGFβ1. No genotoxic insults due to anatase TiO2 NPs alone or to their presence during MNV-1 infection were detected. This study highlights important safety considerations related to NP exposure of the GI tract in individuals infected with noroviruses or other foodborne viruses.</p>","PeriodicalId":92383,"journal":{"name":"International journal of nanotechnology in medicine & engineering","volume":"1 3","pages":"63-73"},"PeriodicalIF":0.0,"publicationDate":"2016-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007025/pdf/nihms972002.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36247654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}