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Mechanical Properties of Cervical Spinal Cord in Neonatal Piglet: In Vitro 新生儿仔猪颈脊髓的力学特性:体外实验
Pub Date : 2020-05-28 DOI: 10.31487/j.nnb.2020.02.08
Anita Singh, R. Magee, Sriram Balasubramanian
The response of neonatal spinal cord tissue to tensile loading is not well-studied. In this study, isolated fresh neonatal cervical spinal cord samples, obtained from twelve 2-4 days old piglets, were tested in uniaxial tension at a rate of 500 mm/min until failure. Maximum load, maximum stress, percentage strain at maximum stress and modulus of elasticity were reported to be 14.6±3.4 N, 0.34±0.11 MPa, 29.3±5.4% and 1.52±0.8 MPa, respectively. These data can help understand the biomechanical behavior of the spinal cord in neonates and can be further used in computational modeling to understand injury mechanisms better and help develop injury prevention strategies.
新生儿脊髓组织对拉伸载荷的反应尚未得到很好的研究。在这项研究中,从12只2-4天大的仔猪身上获得分离的新鲜新生儿颈脊髓样本,以500 mm/min的速度进行单轴拉伸试验,直到失败。最大载荷、最大应力、最大应力下百分比应变和弹性模量分别为14.6±3.4 N、0.34±0.11 MPa、29.3±5.4%和1.52±0.8 MPa。这些数据可以帮助了解新生儿脊髓的生物力学行为,并可以进一步用于计算建模,以更好地了解损伤机制,并帮助制定损伤预防策略。
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引用次数: 1
A Systematic Review of the Electrodiagnostic Assessment of Neonatal Brachial Plexus. 新生儿臂丛神经电诊断评估的系统综述。
Pub Date : 2020-01-01 Epub Date: 2020-06-05 DOI: 10.31487/j.nnb.2020.02.12
Virginia Orozco, Sriram Balasubramanian, Anita Singh

Despite improvements in obstetric care, neonatal brachial plexus palsy continues to significantly impact infants' lives worldwide, with an incidence of 1 to 4 per 1000 live births. While a majority of affected infants recover spontaneously by three months, 20-30% suffer permanent functional deficits that significantly impair their quality of life. Anatomical complexity of the brachial plexus results in varying degrees of injury and pathological changes at multiple levels within the plexus. Current clinical diagnosis relies on electrodiagnostic techniques such as nerve conduction (i.e., motor and sensory) and electromyography studies. These techniques not only aid clinicians to differentiate between axonal and demyelinating lesions, evident by changes in signal shape and conduction, but also provide prognostic information in cases of brachial plexus injuries. The presented study offers a comprehensive review of existing literature on electrodiagnostic techniques employed for assessing neonatal brachial plexus injuries.

尽管产科护理有所改善,但新生儿臂丛神经麻痹继续对全世界婴儿的生命产生重大影响,发病率为每1000例活产1至4例。虽然大多数受影响的婴儿在三个月后会自发康复,但20-30%的婴儿会遭受永久性功能缺陷,严重影响他们的生活质量。臂丛解剖的复杂性导致臂丛内不同程度的损伤和病理改变。目前的临床诊断依赖于电诊断技术,如神经传导(即运动和感觉)和肌电图研究。这些技术不仅可以帮助临床医生区分轴突和脱髓鞘病变,通过信号形态和传导的变化可以看出,而且还可以为臂丛神经损伤的病例提供预后信息。该研究提供了一个全面的审查现有文献的电诊断技术用于评估新生儿臂丛损伤。
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引用次数: 2
Monographie
Pub Date : 2004-01-01 DOI: 10.1163/9789004337862_lgbo_com_131060
Monographie DE Produit
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引用次数: 8
La formation des thèmes désidératifs secondaires 第二期望主题的形成
Pub Date : 2004-01-01 DOI: 10.1163/9789401200936_004
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引用次数: 0
Aperçu général de la catégorie 类别概述
Pub Date : 2004-01-01 DOI: 10.1163/9789401200936_003
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引用次数: 0
La fonction du désidératif 欲望的功能
Pub Date : 2004-01-01 DOI: 10.1163/9789401200936_005
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引用次数: 0
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Neurology and neurobiology (Tallinn, Estonia)
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