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Hippocrates in addiction and the need for transdiagnostic phenotypes to address evidence-based interventions. 成瘾中的希波克拉底以及需要跨诊断表型来解决循证干预问题。
Pub Date : 2025-01-01 Epub Date: 2024-10-18 DOI: 10.1016/j.addbeh.2024.108190
Mauro Pettorruso, Francesco Di Carlo, Giorgio Di Lorenzo, Giovanni Martinotti
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引用次数: 0
Cannabis use regimens in trauma-exposed individuals: Associations with cannabis use quantity and frequency.
Pub Date : 2024-11-16 DOI: 10.1016/j.addbeh.2024.108203
T Snooks, P G Tibbo, P Romero-Sanchiz, S DeGrace, S H Stewart

People with trauma histories have an increased odds of cannabis use. Little is known about the frequency or consequences of different cannabis use regimens in cannabis users with trauma histories. Individuals with anxiety disorders tend to administer benzodiazepines in a pro re nata (PRN; i.e., as needed) as opposed to regularly scheduled (RS, e.g., twice daily [BID], three times daily [TID]) manner. Although physicians tend to prescribe benzodiazepines on a PRN regimen to minimize use, this regimen is paradoxically associated with greater use levels. Indeed, PRN administration regimens may increase use via negative reinforcement processes. We extended this older benzodiazepine literature to cannabis by examining regimen of cannabis use among 94 trauma-exposed cannabis users (mean age = 35.1 years; 52.1 % male; 23.4 % with cannabis prescription). Participants reported their initial and current cannabis use regimen (PRN vs. RS vs. both ['PRN+']) and their past month cannabis use frequency (use occasions in last month) and quantity (grams/use occasion). Consistent with patterns in benzodiazepine research, PRN (47.1 % of sample) and PRN+ (43.5 % of sample) were more common than RS regimens (9.4 % of sample). Also consistent with patterns seen with benzodiazepines, our sample moved toward PRN regimens from initial to current use: e.g., 100 % of initial RS users switched to a regimen that included PRN use. Consistent with predictions emerging from learning theory, PRN and PRN+ cannabis users reported significantly higher cannabis use frequencies compared to RS users (p's < 0.01). Unexpectedly, there were no significant differences between cannabis use regimen groups for quantity of cannabis/occasion. While limited by their cross-sectional nature, with longitudinal replication, result may have implications for identifying cannabis use regimens that minimize frequency of use and thereby reduce risk for negative health outcomes.

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引用次数: 0
The effect of rumination on problematic mobile phone use among female freshmen: A moderated mediation model. 反刍对大一女生使用问题手机的影响:调节中介模型
Pub Date : 2024-11-10 DOI: 10.1016/j.addbeh.2024.108213
Yifan Yu, Chengjie Zhang, Jiaojiao Wan, Yafei Zhang, Lili Ji, Chaoran Chen

Based on the Interaction of Person-Affect-Cognition-Execution model and the risk-buffering model, the current study explored how and when rumination increases problematic mobile phone use (PMPU) among Chinese female freshmen. Specifically, we investigated the underlying mechanism of PMPU by testing a moderated mediation model in which solitude capacity moderated the mediating role of fear of missing out (FoMO) in the relationship between rumination and PMPU. A sample of 1,389 female freshmen in China, with a mean age of 19.68 years (SD = 2.63), was surveyed using the Rumination Response Scale, Fear of Missing Out Scale, Solitude Capacity Scale, and Mobile Phone Addiction Index. Mediation analysis indicated that rumination increases female freshmen's PMPU by heightening FoMO. Moderated mediation analysis further demonstrated that high capacity for solitude mitigated the adverse effects of FoMO on PMPU among female freshmen, whereas low capacity for solitude exacerbates the negative impact of FoMO on PMPU in this group. This study highlights the mediating and moderating mechanisms linking rumination to PMPU. More importantly, it has significant implications for the prevention and intervention of PMPU among female freshmen.

本研究基于 "人-影响-认知-执行 "互动模型和风险缓冲模型,探讨了 "反刍 "如何以及何时增加中国女新生的问题手机使用(PMPU)。具体来说,我们通过检验一个调节中介模型来研究 PMPU 的内在机制,在该模型中,独处能力调节了 "害怕错过"(FoMO)在反刍与 PMPU 关系中的中介作用。研究使用反刍反应量表、害怕缺失量表、独处能力量表和手机成瘾指数对 1389 名中国女新生进行了调查,她们的平均年龄为 19.68 岁(SD = 2.63)。中介分析表明,反刍会通过提高 FoMO 来增加女新生的 PMPU。调节中介分析进一步表明,高独处能力减轻了 FoMO 对女新生 PMPU 的不利影响,而低独处能力则加剧了 FoMO 对该群体 PMPU 的负面影响。这项研究强调了反刍与 PMPU 之间的中介和调节机制。更重要的是,它对预防和干预女新生的 PMPU 具有重要意义。
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引用次数: 0
Role of social-cognitive factors in the relationship between e-cigarette use and subsequent cigarette smoking among U.S. youth: A causal mediation analysis. 社会认知因素在美国青少年使用电子烟与随后吸烟之间关系中的作用:因果中介分析
Pub Date : 2024-11-08 DOI: 10.1016/j.addbeh.2024.108204
Shu Xu, Donna L Coffman, George Luta, Andi Mai, Nan Jiang, Raymond S Niaura

Objective: E-cigarette use is associated with subsequent cigarette smoking among youth. The current study examined the mediating role of social-cognitive factors in this association.

Methods: Data from four waves of the Population Assessment of Tobacco and Health study (2013/4 - 2017/8) were analyzed. Among youth who had heard about e-cigarettes at Wave 1 but never used cigarettes before Wave 2, we conducted both causal and traditional mediation analyses to examine the mediated effect of social-cognitive factors (including relative harm perception of e-cigarettes versus cigarettes, harm perception of e-cigarette use, perceptions of addictiveness of e-cigarette use, and e-cigarette use among best friends) in the association between e-cigarette use and subsequent cigarette ever or current smoking, adjusting for covariates. We included sampling weights in all analyses; hence, results are generalizable to the U.S. youth (12 - 14 years) from the 2013-2014 cohort.

Results: Results from causal mediation analyses indicated that the total effect of e-cigarette use, compared to no use, increased the risk of cigarette ever smoking (20.9 %) and current smoking (4.6 %). A portion of this effect (4.2 % - 15.1 % for ever smoking; less than 10.6 % for current smoking) can be attributed to changes in social-cognitive factors induced by e-cigarette use. However, these mediated effects were small in magnitude relative to their standard errors and not statistically significant. Results from the traditional mediation analyses largely aligned with these findings, except for a few small sized pathways.

Conclusions: For the U.S. youth population, social-cognitive factors may only minimally or not at all mediate the association between e-cigarette use and subsequent cigarette smoking. Further investigation into the mediation role of social-cognitive factors is warranted. Tobacco control interventions that focus on cigarette smoking initiation among youth should target other mediating factors.

目的:青少年使用电子烟与随后吸烟有关。本研究探讨了社会认知因素在这一关联中的中介作用:分析了四波烟草与健康人群评估研究(2013/4 - 2017/8)的数据。在第1波听说过电子烟但在第2波之前从未使用过香烟的青少年中,我们进行了因果分析和传统中介分析,以考察社会认知因素(包括对电子烟与香烟相对危害的认知、对电子烟使用危害的认知、对电子烟使用成瘾性的认知以及最好的朋友中使用电子烟的情况)在电子烟使用与随后的曾经吸烟或当前吸烟之间的关联中的中介作用,并对协变量进行了调整。我们在所有分析中都加入了抽样权重;因此,分析结果可推广至2013-2014年队列中的美国青少年(12-14岁):因果中介分析结果表明,与不使用电子烟相比,使用电子烟的总效应增加了曾经吸烟(20.9%)和目前吸烟(4.6%)的风险。这种影响的一部分(4.2% - 15.1%(曾经吸烟);不到 10.6%(目前吸烟))可归因于使用电子烟引起的社会认知因素的变化。然而,这些中介效应的幅度相对于其标准误差较小,在统计学上也不显著。传统中介分析的结果与这些发现基本一致,只有少数小规模的途径除外:结论:对于美国青少年群体来说,社会认知因素对电子烟使用与后续吸烟之间的关联可能只起了很小的中介作用,甚至根本不起中介作用。有必要进一步调查社会认知因素的中介作用。针对青少年开始吸烟的烟草控制干预措施应针对其他中介因素。
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引用次数: 0
E-cigarette access and age verification among adolescents, young adults, and adults. 青少年、年轻人和成年人吸电子烟的情况和年龄验证。
Pub Date : 2024-11-07 DOI: 10.1016/j.addbeh.2024.108193
Shivani Mathur Gaiha, Lauren Kass Lempert, Crystal Lin, Bonnie Halpern-Felsher

Background: Adolescents and young adults continue to access e-cigarettes despite regulatory efforts to prevent sales to those under 21. Prior research on sources of acquiring e-cigarettes excludes key online sources. This study aims to update evidence on where and how different age groups (adolescents, young adults, and adults) access e-cigarettes.

Methods: A cross-sectional, online survey of 13-40 year-olds who used e-cigarettes in the past 30 days was conducted from November-December 2021.

Study outcomes: where past 30-day users obtained and bought e-cigarettes (retail stores; online, including e-cigarette company and multi-brand websites; social media; home delivery applications; and someone they know); and whether and how age was verified.

Results: In our sample, 55.0% reported obtaining e-cigarettes from retail stores, 44.9% online, and 24.0% from someone they know (n = 2,256), although most 13-17-year-olds obtained their e-cigarettes from someone they know. Double the proportion of 21-40-year-olds (7.0%) and higher than 18-20-year-olds (9.8%), 13.4% of 13-17-year-olds obtained e-cigarettes through social media. Social media, Snapchat, Instagram, and TikTok were common platforms to buy e-cigarettes among those under 21; common sources on social media included friends their age, store/company accounts, and influencers. Approximately 20.0% of those under 21 bought e-cigarettes from internet vendors (including multi-brand websites) and 10.4-15.5% used home delivery applications. Across participants, 14.2% reported that their age was not verified, and 17.8% reported that their age was rarely verified.

Conclusions: A sizeable proportion of adolescents and young adults under 21 years and adults above 21 acquired e-cigarettes from retail and online sources. Less than a quarter of those underage reported having their age verified all the time, warranting enforcement of existing age verification regulation and development of strategies to prevent underage access online.

背景:尽管监管部门努力防止向 21 岁以下人群销售电子烟,但青少年和年轻成年人仍在继续获取电子烟。之前关于电子烟获取渠道的研究不包括主要的网上渠道。本研究旨在更新关于不同年龄组(青少年、年轻成年人和成年人)在哪里以及如何获取电子烟的证据:研究结果:过去 30 天的使用者从哪里获得和购买电子烟(零售店;在线,包括电子烟公司和多品牌网站;社交媒体;送货上门应用;熟人);以及是否和如何验证年龄:在我们的样本中,55.0% 的人报告从零售店获得电子烟,44.9% 的人报告从网上获得电子烟,24.0% 的人报告从熟人处获得电子烟(n = 2,256),尽管大多数 13-17 岁的人是从熟人处获得电子烟的。13.4% 的 13-17 岁青少年通过社交媒体获得电子烟,这一比例是 21-40 岁青少年(7.0%)的两倍,也高于 18-20 岁青少年(9.8%)。社交媒体、Snapchat、Instagram 和 TikTok 是 21 岁以下青少年购买电子烟的常见平台;社交媒体上的常见来源包括同龄朋友、商店/公司账户和有影响力的人。约 20.0% 的 21 岁以下青少年从互联网供应商(包括多品牌网站)购买电子烟,10.4-15.5% 的青少年使用送货上门服务。在所有参与者中,14.2%的人称他们的年龄未得到核实,17.8%的人称他们的年龄很少得到核实:相当一部分 21 岁以下的青少年和 21 岁以上的成年人从零售和网络渠道购买电子烟。不到四分之一的未成年人表示他们的年龄一直得到核实,因此有必要执行现有的年龄核实法规,并制定策略防止未成年人上网。
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引用次数: 0
Mobile phone ownership, social media use, and substance use at ages 11-13 in the ABCD study. ABCD 研究中 11-13 岁儿童的手机拥有率、社交媒体使用率和药物使用率。
Pub Date : 2024-11-06 DOI: 10.1016/j.addbeh.2024.108211
Neal Doran, Natasha E Wade, Kelly E Courtney, Ryan M Sullivan, Joanna Jacobus

Introduction: There is ongoing concern about the impact of increasing use of social media and digital devices on unhealthy behaviors such as substance use in youth. Mobile phone and social media use have been associated with substance use in adolescent and young adult samples, but few studies have evaluated these relationships in younger samples.

Methods: This secondary analysis of data drawn from the ABCD Study examined associations between youth-reported mobile phone ownership and social media use at age 11-12 and use of alcohol, nicotine/tobacco, and cannabis over the next 18 months.

Results: Longitudinal logistic regression was used to test the hypothesis that phone ownership and social media use at age 11-12 would predict substance use over time. Phone ownership was associated with greater odds of alcohol and nicotine/tobacco use, and social media use was associated with greater odds of using nicotine/tobacco and cannabis.

Conclusions: These findings suggest that pre-teen youth who own mobile phones and those who use social media may be at greater risk for substance use. Further research is needed to specify mechanisms by which this association occurs and thus inform prevention and intervention efforts.

简介社交媒体和数字设备的使用日益增多,对青少年使用药物等不健康行为的影响一直备受关注。在青少年和年轻成人样本中,手机和社交媒体的使用与药物使用有关,但很少有研究对年轻样本中的这些关系进行评估:本研究对 ABCD 研究的数据进行了二次分析,考察了 11-12 岁青少年报告的手机拥有量和社交媒体使用量与未来 18 个月内酒精、尼古丁/烟草和大麻使用量之间的关系:我们采用纵向逻辑回归法来检验以下假设:11-12 岁时的手机拥有量和社交媒体使用情况将预测一段时间内的药物使用情况。拥有手机与使用酒精和尼古丁/烟草的几率增加有关,而使用社交媒体与使用尼古丁/烟草和大麻的几率增加有关:这些研究结果表明,拥有手机和使用社交媒体的青春期前青少年使用药物的风险可能更大。需要开展进一步的研究来明确这种关联的发生机制,从而为预防和干预工作提供依据。
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引用次数: 0
Associations and mediating factors between adverse childhood experiences and substance use behaviours in early adulthood: A population-based longitudinal study. 童年不良经历与成年早期药物使用行为之间的关联和中介因素:一项基于人口的纵向研究。
Pub Date : 2024-11-01 DOI: 10.1016/j.addbeh.2024.108194
Deirdre Mongan, Seán R Millar, Margaret M Brennan, Anne Doyle, Brian Galvin, Noel McCarthy

Background: Research has demonstrated positive associations between adverse childhood experiences (ACEs) and substance use behaviours in young adults. However, many of these are based on cross-sectional data. The pathway between ACEs and substance misuse among emerging adults is also not fully understood and few studies have investigated potential mediating factors.

Methods: We analysed data from the Child Cohort of the Growing Up in Ireland study, a nationally representative longitudinal sample of children recruited at 9 years of age (n = 4,729). Logistic regression was used to examine individual and cumulative ACE exposure relationships with substance use at age 20 years. Mediation analyses were used to assess whether parental and peer relationships and school engagement mediate ACE history associations with substance use behaviours.

Results: ACE exposure relationships with current cannabis use, other illicit drug use and problematic drug use were observed. In particular, young adults who had experienced 2 ACEs or 3 + ACEs had an approximate two-fold (OR=1.80, 95 % CI: 1.29, 2.51) and approximate three-fold (OR=2.94, 95 % CI: 2.06, 4.19) increased odds of problematic drug use, respectively, when compared to participants who had experienced no ACEs during the study period. Mediation analyses suggested that parent and peer attachment and liking school partially mediate relationships between ACEs and substance use behaviours.

Conclusions: Children who have experienced ACEs are at higher risk of future substance use and problematic drug use. In supporting these children, identified mediators such as interpersonal relationships and school engagement may help guide selection of prevention interventions.

背景:研究表明,不良童年经历(ACE)与青少年药物使用行为之间存在正相关。然而,其中许多研究都是基于横断面数据。人们对童年逆境经历(ACE)与新成人药物滥用之间的关系还不十分清楚,很少有研究对潜在的中介因素进行调查:我们分析了 "在爱尔兰成长 "研究的儿童队列数据,这是一个具有全国代表性的 9 岁儿童纵向样本(n = 4729)。我们采用逻辑回归法来研究个体和累积的 ACE 暴露与 20 岁时药物使用的关系。中介分析用于评估父母和同伴关系以及学校参与是否能调节 ACE 历史与药物使用行为之间的关系:结果:观察到 ACE 与当前大麻使用、其他非法药物使用和问题药物使用之间的关系。特别是,与在研究期间没有经历过 ACE 的参与者相比,经历过 2 次 ACE 或 3 + ACE 的年轻成年人使用问题药物的几率分别增加了约 2 倍(OR=1.80,95 % CI:1.29,2.51)和约 3 倍(OR=2.94,95 % CI:2.06,4.19)。中介分析表明,父母和同伴的依恋以及对学校的喜爱在一定程度上调节了ACE与药物使用行为之间的关系:结论:经历过 ACE 的儿童未来使用药物和问题药物的风险较高。在为这些儿童提供支持时,人际关系和学校参与等已确定的中介因素可能有助于指导预防干预措施的选择。
{"title":"Associations and mediating factors between adverse childhood experiences and substance use behaviours in early adulthood: A population-based longitudinal study.","authors":"Deirdre Mongan, Seán R Millar, Margaret M Brennan, Anne Doyle, Brian Galvin, Noel McCarthy","doi":"10.1016/j.addbeh.2024.108194","DOIUrl":"https://doi.org/10.1016/j.addbeh.2024.108194","url":null,"abstract":"<p><strong>Background: </strong>Research has demonstrated positive associations between adverse childhood experiences (ACEs) and substance use behaviours in young adults. However, many of these are based on cross-sectional data. The pathway between ACEs and substance misuse among emerging adults is also not fully understood and few studies have investigated potential mediating factors.</p><p><strong>Methods: </strong>We analysed data from the Child Cohort of the Growing Up in Ireland study, a nationally representative longitudinal sample of children recruited at 9 years of age (n = 4,729). Logistic regression was used to examine individual and cumulative ACE exposure relationships with substance use at age 20 years. Mediation analyses were used to assess whether parental and peer relationships and school engagement mediate ACE history associations with substance use behaviours.</p><p><strong>Results: </strong>ACE exposure relationships with current cannabis use, other illicit drug use and problematic drug use were observed. In particular, young adults who had experienced 2 ACEs or 3 + ACEs had an approximate two-fold (OR=1.80, 95 % CI: 1.29, 2.51) and approximate three-fold (OR=2.94, 95 % CI: 2.06, 4.19) increased odds of problematic drug use, respectively, when compared to participants who had experienced no ACEs during the study period. Mediation analyses suggested that parent and peer attachment and liking school partially mediate relationships between ACEs and substance use behaviours.</p><p><strong>Conclusions: </strong>Children who have experienced ACEs are at higher risk of future substance use and problematic drug use. In supporting these children, identified mediators such as interpersonal relationships and school engagement may help guide selection of prevention interventions.</p>","PeriodicalId":93857,"journal":{"name":"Addictive behaviors","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142634282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Problematic pornography use and novel patterns of escalating use: A cross-sectional network analysis with two independent samples 有问题的色情使用和不断升级的使用新模式:两个独立样本的横截面网络分析
Pub Date : 2024-05-01 DOI: 10.1016/j.addbeh.2024.108048
Campbell Ince, L. Albertella, Chang Liu, J. Tiego, L. Fontenelle, Samuel R. Chamberlain, Murat Yücel, Kristian Rotaru
{"title":"Problematic pornography use and novel patterns of escalating use: A cross-sectional network analysis with two independent samples","authors":"Campbell Ince, L. Albertella, Chang Liu, J. Tiego, L. Fontenelle, Samuel R. Chamberlain, Murat Yücel, Kristian Rotaru","doi":"10.1016/j.addbeh.2024.108048","DOIUrl":"https://doi.org/10.1016/j.addbeh.2024.108048","url":null,"abstract":"","PeriodicalId":93857,"journal":{"name":"Addictive behaviors","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141052016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Addictive behaviors
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