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Blood transfusion and surgical treatment increase mortality in patient with proximal humeral fractures. 输血和手术治疗会增加肱骨近端骨折患者的死亡率。
Pub Date : 2023-12-01 Epub Date: 2024-01-13 DOI: 10.1016/j.injury.2023.111091
Ana Belén Fernández-Cortiñas, Teresa Seoane-Pillado, Fernando Marco Martínez

Introduction: Proximal humeral fractures (PHFs) often occur in elderly patients with osteoporosis and associated comorbidities. These patients constitute a special risk group. This study aimed to identify associations between comorbidities, treatment type, and mortality risk.

Patients and methods: We conducted a retrospective chart review of a cohort of 350 patients with a diagnosis of PHF and a mean follow-up of 4.5 years. We analysed the 19 prefracture comorbidities included in the Charlson Comorbidity Index (CCI), haemoglobin (Hb) levels, blood transfusion needs, and treatment administered (surgery versus conservative). The nonparametric Kaplan-Meier method and Cox proportional hazards model were used to estimate the mortality risk.

Results: Over a 4.5-year average follow-up of 350 patients, primarily elderly females, with proximal humerus fractures, several factors were associated with increased mortality. The Charlson Comorbidity Index (CCI) was a significant predictor, with patients having a CCI > 5 facing higher mortality risks, especially if they underwent surgery. Additionally, osteosynthesis was linked to a lower mortality rate compared to arthroplasty. Age, dementia, medical complications, and postfracture Hb level also influenced mortality rates. CONCLUSIóN: These findings emphasize the importance of considering comorbidities, specifically the Charlson Comorbidity Index (CCI), in determining patient outcomes, especially amongst elderly patients with proximal humerus fractures. Factors like age, dementia, and postfracture Hb level also play a crucial role in influencing mortality rates.

Trial registration: The study received written approval from the regional Ethics Committee for Clinical Research (code 2016/125).

简介:肱骨近端骨折(PHF)经常发生在患有骨质疏松症和相关合并症的老年患者身上。这些患者构成了一个特殊的风险群体。本研究旨在确定合并症、治疗类型和死亡风险之间的关联:我们对 350 名确诊为 PHF 的患者进行了回顾性病历审查,平均随访时间为 4.5 年。我们分析了查尔森合并症指数(CCI)中包含的 19 种骨折前合并症、血红蛋白(Hb)水平、输血需求和治疗方法(手术与保守)。采用非参数 Kaplan-Meier 法和 Cox 比例危险模型估算死亡风险:在对 350 名肱骨近端骨折患者(主要是老年女性)进行的平均为期 4.5 年的随访中,有几个因素与死亡率的增加有关。夏尔森综合症指数(CCI)是一个重要的预测因素,CCI>5的患者面临更高的死亡风险,尤其是接受手术的患者。此外,与关节置换术相比,骨合成术的死亡率较低。年龄、痴呆症、内科并发症和骨折后血红蛋白水平也会影响死亡率。结论:这些研究结果强调了考虑合并症,特别是夏尔森合并症指数(CCI)对确定患者预后的重要性,尤其是肱骨近端骨折的老年患者。年龄、痴呆症和骨折后血红蛋白水平等因素也是影响死亡率的关键因素:该研究获得了地区临床研究伦理委员会的书面批准(代码 2016/125)。
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引用次数: 0
Influence of Coronoid fixation on the functional outcome and rate of complications in surgically treated acute complex elbow instability. 冠状面固定对手术治疗急性复杂性肘关节不稳的功能结果和并发症发生率的影响。
Pub Date : 2023-12-01 Epub Date: 2024-01-13 DOI: 10.1016/j.injury.2023.110892
Samuel A Antuña, Riccardo Raganato, Lucia Ros Dopico, Raúl Barco

Introduction: Fractures of the coronoid commonly present in elbow fracture-dislocations. Despite the evidence that the coronoid plays an important role in elbow stability, there is still controversy on which fractures should be surgically fixed. The aim of this study is to compare the clinical outcomes and rate of complications of patients with elbow fracture-dislocations in which the coronoid was fixed or left untreated.

Materials and methods: Thirty-nine patients with an elbow fracture-dislocation involving a coronoid fracture were prospectively followed for an average of 90 months (range 24-190). According to Morrey´s classification there were 22 type II and 8 type III. Nine patients had an anteromedial fracture of the coronoid. In 24 patients the coronoid was repaired (suture fixation in 9, screws fixation in 10 and plate fixation in 5) and in 15 patients the coronoid was not fixed. In 18 patients the radial head was replaced and in 8 patients it was fixed. All patients underwent repair of the lateral ligament complex. Clinical evaluation was performed with the MEPS. Radiographically, the rate of coronoid nonunion was specifically analyzed. Postoperative neurological complications were recorded.

Results: At the most recent follow up, the average arc of flexion-extension was 120° (range 70°-140°) with a mean MEPS of 90 (range 25-100). No statistically significant differences were found in the MEPS and flexion-extension arc between the patients in whom synthesis was performed (117° ROM, and 89 MEPS) and those in whom it was not (122° ROM, 94 MEPS) (p = 0.42; p = 0.34). Coronoid fracture healing could be assessed in 36 patients: in 19 patients the coronoid was radiographically healed, and in 17 a nonunion was present, with no difference in the final clinical outcome between both groups. Nine patients, 6 of whom had undergone coronoid fixation, had a neurological complication related to the ulnar nerve.

Conclusions: Coronoid fractures affecting around 50% of its height can be treated without internal fixation as long as the rest of the osteo-ligamentous structures are adequately repaired. Osteosynthesis of the coronoid through a medial approach may carry a non-negligible risk of associated neurological injury.

导言:冠状突骨折常见于肘部骨折脱位。尽管有证据表明冠状突在肘关节稳定性方面发挥着重要作用,但对于哪些骨折应进行手术固定仍存在争议。本研究的目的是比较肘部骨折脱位患者在冠状突固定和不固定两种情况下的临床疗效和并发症发生率:对39名肘关节骨折脱位伴冠状突骨折的患者进行了平均90个月(24-190个月)的前瞻性随访。根据莫雷分类法,其中22例为II型,8例为III型。9名患者的冠状突前内侧骨折。24例患者的冠状突得到了修复(9例缝合固定,10例螺钉固定,5例钢板固定),15例患者的冠状突未得到固定。18名患者更换了桡骨头,8名患者固定了桡骨头。所有患者都进行了外侧韧带复合体修复。临床评估通过 MEPS 进行。在X光片上,对冠状骨不连的发生率进行了具体分析。记录了术后神经系统并发症:在最近的随访中,患者的平均屈伸弧度为 120°(范围为 70°-140°),平均 MEPS 为 90(范围为 25-100)。在MEPS和屈伸弧度方面,进行过综合治疗的患者(117° ROM和89 MEPS)与未进行综合治疗的患者(122° ROM和94 MEPS)之间没有发现明显的统计学差异(P = 0.42;P = 0.34)。有36名患者的冠状面骨折愈合情况可以进行评估:19名患者的冠状面骨折在影像学上已经愈合,17名患者的冠状面骨折出现了不愈合,两组患者的最终临床结果没有差异。9名患者(其中6人接受了冠状突固定术)出现了与尺神经有关的神经并发症:结论:只要骨韧带结构的其他部分得到充分修复,影响约50%高度的冠状面骨折无需内固定即可治疗。通过内侧入路对冠状面进行骨合成可能会带来不可忽视的相关神经损伤风险。
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引用次数: 0
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Injury
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