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Update on new oral cephalosporins 新的口服头孢菌素的最新情况
Antimicrobic Newsletter
Pub Date : 1992-03-01 DOI: 10.1016/0738-1751(92)90003-S
Steven L. Barriere

Only cefprozil and cefpodoxime have been shown to be more effective than comparison agents, and they appear to better tolerated than amoxicillin-containing regimens. The potent Gram-negative activity of cefpodoxime is attractive for selective clinical situations (e.g., in place of a quinolone). However, it has not been tested for the treatment of serious Gram-negative infections. Either of these agents would appear to be preferable to cefaclor in terms of efficacy, safety, and cost. Usage patterns similar to that currently applicable to cefaclor should also be applied to the use of either of these drugs, as they should be reserved for patients who have not responded to first-line therapy or in penicillin-allergic patients who cannot tolerate erythromycin or trimethoprimsulfamethoxazole.

只有头孢丙烯和头孢多肟已被证明比比较剂更有效，而且它们似乎比含阿莫西林的方案耐受性更好。头孢多肟的强效革兰氏阴性活性对选择性临床情况(例如，代替喹诺酮类药物)具有吸引力。然而，它还没有被测试用于治疗严重的革兰氏阴性感染。这些药物中的任何一种在疗效、安全性和成本方面似乎都优于头孢克洛。这两种药物的使用模式也应与目前适用于头孢克洛的使用模式类似，因为它们应保留给对一线治疗无反应的患者或不能耐受红霉素或甲氧苄氨嘧啶甲恶唑的青霉素过敏患者。
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引用次数: 1
The MIC: Myth and reality MIC:神话与现实
Antimicrobic Newsletter
Pub Date : 1992-02-01 DOI: 10.1016/0738-1751(92)90017-5
Daniel Amsterdam
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引用次数: 8
Editor's note 编者按
Antimicrobic Newsletter
Pub Date : 1992-02-01 DOI: 10.1016/0738-1751(92)90016-4
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引用次数: 0
E test, an antimicrobial susceptibility testing method with broad clinical and epidemiologic application E试验是一种临床和流行病学应用广泛的抗菌药物敏感性试验方法
Antimicrobic Newsletter
Pub Date : 1992-01-01 DOI: 10.1016/0738-1751(92)90015-3
Martha L. Sanchez, Ronald N. Jones
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引用次数: 60
Editor's note 编者按
Antimicrobic Newsletter
Pub Date : 1992-01-01 DOI: 10.1016/0738-1751(92)90014-2
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引用次数: 0
Editor's note 编者按
Antimicrobic Newsletter
Pub Date : 1990-11-01 DOI: 10.1016/0738-1751(90)90026-9
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引用次数: 0
The antimicrobic newsletter, volume 7 index 抗菌剂通讯，第7卷索引
Antimicrobic Newsletter
Pub Date : 1990-11-01 DOI: 10.1016/0738-1751(90)90028-B
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引用次数: 0
Update on glycopeptide resistance in enterococci 肠球菌糖肽耐药的最新进展
Antimicrobic Newsletter
Pub Date : 1990-11-01 DOI: 10.1016/0738-1751(90)90027-A
Sylvie Dutka-Malen, Patrice Courvalin
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引用次数: 14
Editor's note 编者按
Antimicrobic Newsletter
Pub Date : 1990-10-01 DOI: 10.1016/0738-1751(90)90044-D
Harold C. Neu
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引用次数: 0
Fluoroquinolones—Where are we? 氟喹诺酮类药物-我们在哪里?
Antimicrobic Newsletter
Pub Date : 1990-10-01 DOI: 10.1016/0738-1751(90)90046-F
Harold C. Neu
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引用次数: 0
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