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Complications of intravesical bacillus Calmette-Guerin for superficial bladder cancer 膀胱内卡介苗治疗浅表性膀胱癌的并发症
Antimicrobics and Infectious Diseases Newsletter
Pub Date : 1997-04-01 DOI: 10.1016/S1069-417X(00)80017-5
MD William B. Harley
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引用次数: 0
The Spectrum of FUOs in the '90s 90年代fuo的频谱
Antimicrobics and Infectious Diseases Newsletter
Pub Date : 1997-04-01 DOI: 10.1016/S1069-417X(00)80016-3
MD Stephen Dummer (Professor of Medicine)
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引用次数: 3
The use of the erythrocyte sedimentation rate, the C-reactive protein assay, and procalcitonin concentrations in the assessment of the potentially infected patient 使用红细胞沉降率、c反应蛋白测定和降钙素原浓度来评估潜在感染患者
Antimicrobics and Infectious Diseases Newsletter
Pub Date : 1997-03-01 DOI: 10.1016/S1069-417X(97)80002-7
N. Midha
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引用次数: 1
The use of the erythrocyte sedimentation rate, the C-reactive protein assay, and procalcitonin concentrations in the assessment of the potentially infected patient 使用红细胞沉降率、c反应蛋白测定和降钙素原浓度来评估潜在感染患者
Antimicrobics and Infectious Diseases Newsletter
Pub Date : 1997-03-01 DOI: 10.1016/S1069-417X(97)80002-7
Narinder K. Midha MS M(ASCP) SM, DLM (Assistant Director)
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引用次数: 1
Disseminated Mycobacterium avium complex infection in AIDS patients: Detection, prevention, and treatment 艾滋病患者弥散性鸟分枝杆菌复合感染:检测、预防和治疗
Antimicrobics and Infectious Diseases Newsletter
Pub Date : 1997-03-01 DOI: 10.1016/S1069-417X(97)80001-5
Ross G. Hewitt MD
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引用次数: 0
Disseminated Mycobacterium avium complex infection in AIDS patients: Detection, prevention, and treatment 艾滋病患者弥散性鸟分枝杆菌复合感染:检测、预防和治疗
Antimicrobics and Infectious Diseases Newsletter
Pub Date : 1997-03-01 DOI: 10.1016/S1069-417X(97)80001-5
R. Hewitt
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引用次数: 0
Enterococcal mechanisms of resistance against cell wall-active agents 肠球菌对细胞壁活性剂的耐药性机制
Antimicrobics and Infectious Diseases Newsletter
Pub Date : 1997-02-01 DOI: 10.1016/S1069-417X(00)80014-X
MD Charles W. Stratton

It is clear that enterococcal mechanisms of resistance against cell wall-active agents have become increasingly important. These mechanisms are complex and most likely related to the stringent response and dormancy. Neither newer investigational antimicrobial agents such as fluoroquinolones nor older agents such as tetracyclines, alone or in combination, have been shown to be effective substitutes for the combination of a penicillin and an aminoglycoside against enterococci. This current lack of alternative therapy reemphasizes the importance of enterococcal mechanisms of resistance against cell wall-active agents.

很明显，肠球菌抵抗细胞壁活性药物的机制已经变得越来越重要。这些机制是复杂的，很可能与严格的反应和休眠有关。新的研究性抗菌药物，如氟喹诺酮类药物，或较老的药物，如四环素，单独或联合使用，均未被证明是青霉素和氨基糖苷联合治疗肠球菌的有效替代品。目前替代疗法的缺乏再次强调了肠球菌对细胞壁活性药物耐药机制的重要性。
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引用次数: 0
Issues for chlamydial susceptibility testing 衣原体药敏试验问题
Antimicrobics and Infectious Diseases Newsletter
Pub Date : 1997-02-01 DOI: 10.1016/S1069-417X(00)80015-1
MD Charles W. Stratton

It becomes painfully clear that there are a number of critical issues that must be addressed if susceptibility testing of chlamydiae is going to be regarded in the same light as that for other microorganisms. The NCCLS should be encouraged to institute a subcommittee to study this problem as has been done with other areas of susceptibility testing. It is through this consensus mechanism that uniformity of testing, if not clinical relevance will be achieved.

很明显，如果要像对待其他微生物一样对待衣原体的敏感性测试，就必须解决一些关键问题。应当鼓励国家药品安全委员会设立一个小组委员会来研究这个问题，就像对其他敏感试验领域所做的那样。通过这种共识机制，即使不能实现临床相关性，也可以实现检测的一致性。
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引用次数: 0
From plagues to prions — all microbial life is here 从瘟疫到朊病毒，所有的微生物生命都在这里
Antimicrobics and Infectious Diseases Newsletter
Pub Date : 1997-01-01 DOI: 10.1016/S1069-417X(00)80013-8
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引用次数: 0
Chlamydia pneumonae: A Treatable Cause of Atherosclerosis? 肺炎衣原体:动脉粥样硬化的可治疗原因?
Antimicrobics and Infectious Diseases Newsletter
Pub Date : 1997-01-01 DOI: 10.1016/S1069-417X(00)80011-4
James A.S. Muldowney III

Investigations into the mechanisms of atherosclerosis have traditionally centered around endothelial cell function, lipid metabolism, and more recently oxidative stress. The research described here provides a unique approach to our understanding of atherogenesis and complements our current understanding that endothelial cell dysfunction is an early event essential to the onset of the inflammatory response that leads to plaque formation. A combined basic and clinical research approach would provide insight into the mechanism by which C. pneumoniae is involved in atherogenesis and potentially provide important novel therapeutic approaches to the prevention of atherosclerosis.

对动脉粥样硬化机制的研究传统上以内皮细胞功能、脂质代谢和最近的氧化应激为中心。本文描述的研究为我们理解动脉粥样硬化提供了一种独特的方法，并补充了我们目前的理解，即内皮细胞功能障碍是导致斑块形成的炎症反应发生的早期事件。基础研究和临床研究相结合的方法将有助于深入了解肺炎支原体参与动脉粥样硬化形成的机制，并可能为预防动脉粥样硬化提供重要的新治疗方法。
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引用次数: 2
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