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Cardiovascular Revascularization Medicine: Interesting Cases最新文献

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A case series of plug-based closure of peri-device leak after left atrial appendage occlusion 左心耳闭塞术后器械周围漏的塞式封堵一例
Pub Date : 2025-06-27 DOI: 10.1016/j.crmic.2025.100087
Nina S. Appareddy , Gabriel Areoye , Shan Tandon , Divyanshi Sood , Suhaib El Khatib , William Charles Stout , Kathleen Brown , George Gibson , Derar Albashaireh , Bhavith Aruni
Peri-device leak (PDL) following left atrial appendage occlusion (LAAO) is particularly problematic in patients with both high thromboembolic and bleeding risk. We present a case series of three patients with atrial fibrillation and high bleeding risk. All three patients underwent LAAO with a Watchman™ and were found to have PDL on follow-up imaging. All three patients underwent successful PDL closure with an Amplatzer™ duct occluder II device with no complications noted. These cases demonstrate that PDL closure can be safely and effectively performed via a plug-based approach. Imaging is critical in determining candidacy for and method of PDL closure.
左心耳闭塞(LAAO)后的装置周围泄漏(PDL)在血栓栓塞和出血风险高的患者中尤其成问题。我们提出一个病例系列的三个病人心房颤动和高出血的风险。所有3例患者均使用Watchman™进行LAAO检查,并在随访影像中发现PDL。所有3例患者均使用Amplatzer™II型导管闭塞器成功闭合PDL,无并发症发生。这些案例表明,通过基于插件的方法可以安全有效地执行PDL关闭。影像学是决定PDL闭合的候选性和方法的关键。
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引用次数: 0
Transcatheter edge-to-edge repair of the systemic atrioventricular valve in a patient with congenitally corrected transposition of the great arteries and dextrocardia 先天性大动脉转位和右心的系统性房室瓣膜经导管边缘到边缘修复1例
Pub Date : 2025-06-20 DOI: 10.1016/j.crmic.2025.100086
Georgios E. Papadopoulos , Ilias Ninios , George Giannakoulas , Sotirios Evangelou , Andreas Ioannides , Vlasis Ninios
A 33-year-old male with congenitally corrected transposition of the great arteries (ccTGA), dextrocardia and situs solitus presented with dyspnea at rest, classified as New York Heart Association (NYHA) class IV, in the context of severe systemic atrioventricular valve (SAVV) regurgitation, and impaired systolic function of the systemic morphologically right ventricle. Due to high surgical risk, the Heart Team opted for a transcatheter edge-to-edge repair (TEER) using a PASCAL ACE device. The procedure successfully reduced regurgitation from severe to mild, resulting in symptomatic improvement and recovery to NYHA class I at six-month follow-up. This case highlights the feasibility of TEER as a minimally invasive alternative in selected patients with ccTGA and systemic AV valve regurgitation.
一例33岁男性先天性大动脉转位(ccTGA)、右心和孤立位,静止时呼吸困难,纽约心脏协会(NYHA) IV级,严重系统性房室瓣膜(SAVV)反流,系统性右心室收缩功能受损。由于手术风险高,心脏小组选择使用PASCAL ACE装置进行经导管边缘到边缘修复(TEER)。该手术成功地将反流从严重减轻到轻度,导致症状改善,并在六个月的随访中恢复到NYHA I级。本病例强调了TEER作为ccTGA和系统性房室瓣膜返流患者的微创替代方案的可行性。
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引用次数: 0
Anomalous left main coronary artery originating from the right coronary cusp: A case series and clinical implications 起源于右冠状动脉尖的左冠状动脉主干异常:一个病例系列和临床意义
Pub Date : 2025-06-12 DOI: 10.1016/j.crmic.2025.100084
Ghulam Mujtaba Ghumman , Adel Kanaan , Sanam Farooq , Abdul Baqi , F.N.U. Salman , Moaaz Baghal , Syed Sohail Ali

Background

Anomalous origin of the left main coronary artery (LMCA) from the right coronary cusp is a rare congenital anomaly with diverse clinical presentations and significant implications for patient management.

Case summary

This case series presents three unique cases of anomalous LMCA origin from the right coronary cusp, each with distinct clinical manifestations and management strategies. Case 1 involved an 82-year-old male presenting with heart failure symptoms, where coronary angiography revealed an anomalous LMCA with a retro-aortic course (benign), managed conservatively. Case 2 describes a 71-year-old female presenting with non-ST-segment elevation myocardial infarction (NSTEMI) due to a culprit right coronary artery (RCA) lesion, with the LMCA taking a pre-pulmonic course (benign), successfully treated with percutaneous coronary intervention (PCI) of the RCA. Case 3 details a 76-year-old male evaluated for exertional fatigue and abnormal stress test, found to have an anomalous LMCA with a malignant interarterial course, for which surgical revascularization was recommended, though the patient opted for conservative management.

Discussion

The series underscores the importance of recognizing LMCA anomalies and tailoring management strategies based on anatomical course and clinical presentation. Coronary computed tomography angiography (CTA) plays a pivotal role in delineating coronary anatomy and guiding management. Benign courses are managed conservatively, while malignant interarterial courses necessitate surgical consideration due to the increased risk of sudden cardiac death.

Conclusion

Anomalous origin of the LMCA from the right coronary cusp presents diagnostic and therapeutic challenges, requiring a multidisciplinary approach for optimal management. Early identification and accurate characterization of the coronary course are critical for guiding intervention and improving outcomes.
背景:左主干冠状动脉(LMCA)起源于右冠状动脉尖是一种罕见的先天性异常,临床表现多样,对患者治疗有重要意义。本病例系列报告了三个独特的起源于右冠状动脉尖的LMCA异常病例,每个病例都有不同的临床表现和治疗策略。病例1为一82岁男性,表现为心力衰竭症状,冠状动脉造影显示LMCA异常伴主动脉后病变(良性),保守治疗。病例2描述了一名71岁女性,由于右冠状动脉(RCA)病变导致非st段抬高型心肌梗死(NSTEMI), LMCA采取肺前病程(良性),经RCA经皮冠状动脉介入治疗(PCI)成功治疗。病例3详细描述了一名76岁男性,因劳累疲劳和异常压力测试而接受评估,发现LMCA异常伴恶性动脉间程,建议手术重建术,但患者选择保守治疗。该系列强调了识别LMCA异常和根据解剖过程和临床表现定制管理策略的重要性。冠状动脉ct血管造影(CTA)在描绘冠状动脉解剖结构和指导治疗方面起着关键作用。良性病程保守处理,而恶性动脉间病程由于心源性猝死的风险增加,需要手术治疗。结论右冠状动脉尖部LMCA异常起源给诊断和治疗带来挑战,需要多学科联合治疗。早期识别和准确描述冠状动脉病程对指导干预和改善预后至关重要。
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引用次数: 0
When complications become opportunities: Guide catheter-induced dissection facilitating an unplanned investment strategy in chronic total occlusion PCI of the RCA 当并发症成为机会时:引导导管诱导的夹层有助于RCA慢性全闭塞PCI的计划外投资策略
Pub Date : 2025-06-11 DOI: 10.1016/j.crmic.2025.100085
Ghulam Mujtaba Ghumman, Sidra Kalsoom, Mohammed Taleb, Syed Sohail Ali, Zaid Al-Jebaje

Background

Percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) of the right coronary artery (RCA) remains technically challenging. Guide catheter-induced dissection is typically considered a serious complication. However, in rare cases, such events may paradoxically aid in successful revascularization.

Case Summary

We report the case of a 43-year-old male with prior coronary artery bypass grafting (CABG) and RCA CTO, who underwent unplanned investment PCI procedure. Immediately after guide catheter engagement, contrast injection revealed a proximal RCA dissection. Instead of terminating the procedure, this unintentional dissection enabled entry into the subintimal space and facilitated guidewire passage to the distal branches. Intravascular ultrasound (IVUS) confirmed entry into the false lumen. Serial balloon angioplasty was performed, restoring TIMI-III flow to the right posterior descending artery (RPDA) and right posterolateral artery (RPLA). Remarkably, the dissection did not extend to the aortic cusp, nor did it result in perforation or pericardial effusion. The case was deemed a successful investment procedure, with staged completion in 10 weeks when patient returned for definitive revascularization. Four overlapping stents were placed from ostial RCA to RPLA with excellent results.

Conclusion

While coronary dissection during CTO-PCI is conventionally viewed as a complication, in select scenarios it may facilitate revascularization. Recognizing and managing such outcomes requires careful intraprocedural assessment and expertise in complex PCI.
背景:右冠状动脉慢性全闭塞(CTO)的经皮冠状动脉介入治疗(PCI)在技术上仍然具有挑战性。导尿管诱导的夹层通常被认为是一种严重的并发症。然而,在极少数情况下,这些事件可能反而有助于成功的血运重建。我们报告一例43岁男性患者,术前行冠状动脉旁路移植术(CABG)和RCA CTO,行计划外的PCI手术。导管接合后,造影剂注射立即显示近端RCA剥离。而不是终止手术,这种无意的剥离使进入内膜下空间,并促进导丝通道到远端分支。血管内超声(IVUS)证实进入假腔。连续球囊血管成形术,恢复TIMI-III血流至右后降支(RPDA)和右后外侧动脉(RPLA)。值得注意的是,夹层没有延伸到主动脉尖,也没有导致穿孔或心包积液。该病例被认为是一个成功的投资程序,在10周内分阶段完成,患者返回进行最终的血运重建术。4个重叠支架从开口RCA放置到RPLA,效果良好。结论在CTO-PCI术中冠状动脉夹层通常被认为是一种并发症,但在某些情况下,冠状动脉夹层可促进血管重建术。识别和管理这些结果需要仔细的术中评估和复杂PCI的专业知识。
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引用次数: 0
“Atrialized” minimally invasive transcatheter mitral valve-in-MAC replacement to prevent outflow tract obstruction “心房化”微创经导管二尖瓣置换术预防流出道阻塞
Pub Date : 2025-06-06 DOI: 10.1016/j.crmic.2025.100081
Luai Madanat, Richard Bloomingdale, Ahmad Jabri, Michael Gallagher, Vishal Birk, Amr E. Abbas, John Young, Rakesh M. Suri
Mitral valve replacement in the setting of severe mitral annular calcification remains a high-risk intervention, often complicated by poor outcomes with both conventional surgical and transcatheter techniques. A hybrid open transcatheter mitral valve-in-MAC procedure utilizing an atrialized implantation strategy offers a promising alternative to minimize the risk of left ventricular outflow tract obstruction. Meticulous preoperative planning with cardiac CT is essential to guide procedural strategy and optimize outcomes.
在严重二尖瓣环钙化的情况下,二尖瓣置换术仍然是一种高风险的干预措施,传统的外科手术和经导管技术往往导致预后不佳。采用房源化植入策略的混合经导管二尖瓣植入mac手术为降低左心室流出道梗阻的风险提供了一种有希望的选择。细致的术前计划与心脏CT是必不可少的指导手术策略和优化结果。
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引用次数: 0
TRI-umphant recovery: A case series of transcatheter tricuspid valve-in-valve replacement for bioprosthetic tricuspid valve stenosis 三突恢复:经导管三尖瓣瓣内置换术治疗生物假体三尖瓣狭窄一例
Pub Date : 2025-06-04 DOI: 10.1016/j.crmic.2025.100082
Nina S. Appareddy , Bradley Casey , Divyanshi Sood , Renuka Singh , Syed R. Zaidi , Manaquibb Khan , George Gibson , Bhavith Aruni , Derar Albashaireh
Transcatheter tricuspid valve-in-valve (TViV) replacement is an emerging alternative to repeat surgical intervention for patients with bioprosthetic tricuspid valve stenosis. We present two patients with a history of severe tricuspid regurgitation and bioprosthetic tricuspid valve replacement, one with a history of Ebstein's anomaly and the other with a history of blunt chest trauma. Both patients presented several years later with severe bioprosthetic tricuspid valve stenosis symptomatic with progressive lifestyle limiting dyspnea. Following multi-disciplinary discussion, they were both determined to be of high surgical risk and ultimately managed via a transcatheter approach with TViV replacement.
经导管三尖瓣瓣内置换术(TViV)是生物假体三尖瓣狭窄患者重复手术干预的一种新兴替代方法。我们报告了两例有严重三尖瓣反流和生物假体三尖瓣置换术史的患者,其中一例有Ebstein异常史,另一例有钝性胸部外伤史。两例患者几年后均出现严重的生物假体三尖瓣狭窄症状,伴有进行性生活方式限制性呼吸困难。经过多学科的讨论,他们都被确定为高手术风险,最终通过经导管入路和TViV置换术进行治疗。
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引用次数: 0
Extrinsic left main coronary artery compression in pulmonary hypertension with syncope debut 肺动脉高压伴晕厥的外源性冠状动脉左主干受压
Pub Date : 2025-06-01 DOI: 10.1016/j.crmic.2025.100079
Alejandro Ricalde Alcocer , Oscar Ulises Preciado-Gutiérrez , Mariana García Villarejo , Mauricio Kuri , Gerardo Payró
Extrinsic left main coronary artery (LMCA) compression is a rare condition, often associated with pulmonary artery hypertension. We present the first reported case of extrinsic LMCA compression manifesting as syncope in a 35-year-old woman. Imaging confirmed significant LMCA compression due to pulmonary artery enlargement. Percutaneous coronary intervention with a third-generation stent successfully relieved the obstruction. At five-year follow-up, the stent remained patent without restenosis or fracture. This case highlights the importance of early diagnosis using multimodal imaging and demonstrates angioplasty as a safe, effective alternative for managing LMCA compression in high-risk patients.
外源性左主干冠状动脉压迫是一种罕见的疾病,通常与肺动脉高压有关。我们提出了第一例外源性LMCA压迫表现为晕厥在一个35岁的妇女。影像学证实肺动脉扩张导致明显的LMCA压迫。经皮冠状动脉介入治疗与第三代支架成功解除阻塞。在5年的随访中,支架保持通畅,无再狭窄或骨折。本病例强调了早期诊断使用多模态成像的重要性,并证明血管成形术是一种安全、有效的治疗高危患者LMCA压迫的替代方法。
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引用次数: 0
Zero contrast concomitant transcatheter aortic valve and coronary intervention in a patient with severe contrast allergy 严重对比剂过敏患者的无对比剂联合经导管主动脉瓣冠状动脉介入治疗
Pub Date : 2025-06-01 DOI: 10.1016/j.crmic.2025.100080
William Camilleri, Joost Daemen, Nicolas M. Van Mieghem
The incidence of severe contrast allergy ranges from 0.01 to 0.04 % and can result in severe life threatening complications. We present a case of simultaneous TAVR for pure AR and LM PCI using zero contrast due to severe contrast allergy.
严重对比过敏的发生率从0.01到0.04%不等,可导致严重的危及生命的并发症。我们提出一个病例同时TAVR纯AR和LM PCI使用零对比由于严重的对比过敏。
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引用次数: 0
Erroneously deployed, old ostial RCA stent, overhanging in the aorta with symptomatic ostial severe ISR, snared, stented and successfully averted single vessel bypass 错误部署,旧的鼻腔RCA支架,悬垂在有症状的鼻腔严重ISR的主动脉,陷阱,支架和成功避免单血管旁路
Pub Date : 2025-05-28 DOI: 10.1016/j.crmic.2025.100078
Birgurman Singh , Christopher James Murray , Allan Santos Argueta , Usman Baber , Nirmal Kaur
We present a complex case of a 77-year-old high-surgical-risk patient with refractory angina due to severe in-stent restenosis (ISR) of a malpositioned right coronary artery (RCA) ostial stent protruding into the Aorta. Despite prior PCIs, including overlapping drug-eluting stents (DES), progressive ISR led to debilitating symptoms. Diagnostic imaging revealed an 8–10 mm aortic overhang of the RCA stent, complicating catheter engagement. A multidisciplinary team pursued percutaneous management to avoid high-risk CABG. Using femoral access and a temporary pacemaker, a malpositioned stent was successfully snared and removed. Subsequent OCT-guided PCI involved distal 3.0 × 32 mm and ostial 3.5 × 16 mm PROMUS DES deployment, optimized with intravascular imaging. The procedure restored TIMI III flow, resolving symptoms without complications. This case demonstrates the successful percutaneous retrieval and imaging-guided PCI for aortic-ostial ISR, highlighting the importance of careful planning, advanced interventional techniques, and a multidisciplinary approach to minimize the need for invasive surgery in high-risk patients.
我们报告了一个复杂的病例,77岁的高手术风险患者,由于右冠状动脉(RCA)口支架突出到主动脉的位置不正确,导致严重的支架内再狭窄(ISR),导致难治性心绞痛。尽管先前有pci,包括重叠药物洗脱支架(DES),进行性ISR导致衰弱症状。诊断影像显示RCA支架上有8 - 10mm的主动脉悬垂,并发导管接合。一个多学科团队采用经皮治疗以避免高风险的冠脉搭桥。使用股骨通道和临时起搏器,一个错位的支架被成功捕获并移除。随后的oct引导PCI涉及远端3.0 × 32 mm和口部3.5 × 16 mm PROMUS DES部署,并通过血管内成像进行优化。该手术恢复了TIMI III型血流,消除了症状,无并发症。本病例展示了经皮穿刺和成像引导下PCI治疗主动脉-口ISR的成功,强调了精心规划、先进介入技术和多学科方法的重要性,以尽量减少高风险患者对侵入性手术的需求。
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引用次数: 0
Pneumopericardium after pericardiocentesis 心包穿刺后心包充血
Pub Date : 2025-05-15 DOI: 10.1016/j.crmic.2025.100077
Giuseppe Andò, Alessio Villari, Giulia Cavolina, Olimpia Trio
Pericardial effusion is a common clinical finding that can arise from a wide range of etiologies, including infections, malignancies, autoimmune disorders, and iatrogenic causes. Management often requires pericardiocentesis, particularly when large effusions cause hemodynamic compromise or diagnostic clarification is necessary. While pericardiocentesis is generally a safe procedure when performed under imaging guidance, complications can still occur, particularly in elderly patients or those receiving anticoagulation therapy. One rare but important complication is pneumopericardium—the presence of air within the pericardial space—which may result in serious consequences such as cardiac tamponade or pericardial irritation if not promptly recognized and managed.
心包积液是一种常见的临床表现,可由多种病因引起,包括感染、恶性肿瘤、自身免疫性疾病和医源性原因。治疗通常需要心包穿刺,特别是当大量积液导致血流动力学损害或诊断需要澄清时。虽然在影像学指导下进行心包穿刺通常是安全的,但仍可能发生并发症,特别是在老年患者或接受抗凝治疗的患者中。一种罕见但重要的并发症是心包气——心包空间内存在空气——如果不及时发现和处理,可能导致严重的后果,如心包填塞或心包刺激。
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引用次数: 0
期刊
Cardiovascular Revascularization Medicine: Interesting Cases
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