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Acute colonic pseudo-obstruction after endoscopic resection of a fully circumferential large colon polyp 内镜下全周大结肠息肉切除术后急性结肠假性梗阻
Pub Date : 2025-12-01 DOI: 10.1016/j.igie.2025.05.006
Aein Zarrin MD , Shirley Jiang MD , Rajit Gilhotra MD , Neal Shahidi MD, PhD
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引用次数: 0
Water pressure–assisted endoscopic stricturotomy with band-assisted mucosectomy and polypectomy for a complex colonic stricture in Crohn’s disease guided by preprocedure intestinal ultrasound 术前肠超声引导下,水压内镜下狭窄切除术联合带式粘膜切除术和息肉切除术治疗克罗恩病复杂结肠狭窄
Pub Date : 2025-12-01 DOI: 10.1016/j.igie.2025.09.004
Partha Pal MD, DNB , Mohammad Abdul Mateen DMRD, DNB , Pradeep Rebala MS, MCh , Rajesh Gupta MD, DM , Manu Tandan MD, DM , D.Nageshwar Reddy MD, DM, MASGE, AGAF
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引用次数: 0
Status of training in the use of lumen-apposing metal stents for therapeutic endoscopic ultrasound during advanced endoscopy fellowship: a survey questionnaire 在高级内窥镜研究期间,使用腔内金属支架治疗内窥镜超声的培训状况:一份调查问卷
Pub Date : 2025-12-01 DOI: 10.1016/j.igie.2025.09.003
Yasi Xiao MD , Maham Hayat MD , Abdul S. Mohammed MD , Abdullah Abbasi MD , Sagar Pathak MD , Saurabh Chandan MD , Daryl Ramai MD , Deepanshu Jain MD , Muhammad K. Hasan MD , Mustafa A. Arain MD , Kambiz K. Kadkhodayan MD , Natalie Cosgrove MD , Dennis Yang MD

Background and Aims

The lumen-apposing metal stent (LAMS) has revolutionized endoscopic ultrasound (EUS). However, there is a paucity of data on the optimal approaches to training on the use of LAMSs. This survey study aimed to evaluate the status of training in LAMSs among advanced endoscopy fellowship (AEF) trainees.

Methods

AEF (academic year 2023-2024) trainees were invited to complete a 15-question survey on LAMS training. The questions included the following domains: demographics, exposure to LAMSs before AEF, number of observed and hands-on participation using LAMSs for EUS-guided pancreatic fluid collection drainage (EUS-PFCD), choledochoduodenostomy (EUS-CD), gallbladder drainage (EUS-GBD), and gastrojejunostomy (EUS-GJ) and EUS-directed transgastric endoscopic retrograde cholangiopancreatography (EDGE). Trainees were asked about their level of confidence in performing these procedures independently upon completion of their AEF.

Results

Forty-three of 92 trainees completed the survey. Trainees reported performing a median of 400 (interquartile range [IQR], 305-525) EUS and 405 (IQR, 345-500) endoscopic retrograde cholangiopancreatography procedures. Most (88.4%) had exposure to hands-on LAMS training in explant/inanimate models during their AEF. More than one-half of trainees (23; 53.5%) reported hands-on participating in >10 EUS-PFCD cases but ≤2 for each of the non-pancreatic fluid collection drainage (PFCD) indications. Although most trainees (88.4%) reported feeling confident in their ability to perform EUS-PFCD independently, only 34.9% and 39.6% indicated being confident for EUS-GJ and EUS-CD, respectively. Trainees who were confident had a significantly greater mean number of hands-on cases during AEF training when compared with their nonconfident counterparts.

Conclusions

This study demonstrates significant variability in LAMS training exposure during AEF, with few hands-on opportunities for non-PFCD indications. Additional research is needed to establish optimal approaches to training in LAMS procedures.
背景与目的腔内金属支架(LAMS)彻底改变了内镜超声(EUS)。但是,缺乏关于使用lams的最佳训练方法的数据。本调查研究旨在评估高级内窥镜奖学金(AEF)学员在lams培训中的状况。方法邀请saef(2023-2024学年)学员完成15个问题的LAMS培训调查。问题包括以下领域:人口统计学,AEF前暴露于lams,观察和实际参与使用lams进行eus引导的胰液收集引流(EUS-PFCD),胆十二指肠吻合术(EUS-CD),胆囊引流(EUS-GBD),胃空肠吻合术(EUS-GJ)和eus引导的经胃内镜逆行胆管造影术(EDGE)的人数。受训人员被问及他们在完成AEF后独立执行这些程序的信心程度。结果92名学员中有43人完成了问卷调查。受训人员报告的中位数为400例(四分位数范围[IQR], 305-525) EUS和405例(IQR, 345-500)内窥镜逆行胆管造影。大多数(88.4%)在AEF期间接受了外植体/无生命模型的动手LAMS培训。超过一半的受训者(23;53.5%)报告亲身参与了10例EUS-PFCD病例,但每个非胰液收集引流(PFCD)适应症≤2例。尽管大多数受训者(88.4%)表示对自己独立执行EUS-PFCD的能力有信心,但分别只有34.9%和39.6%的受训者表示对EUS-GJ和EUS-CD有信心。与不自信的学员相比,自信的学员在AEF培训期间有更多的实际操作案例。结论:本研究表明AEF期间LAMS训练暴露存在显著差异,非pfcd适应症的实践机会很少。需要进一步的研究,以确定最佳的训练方法,在LAMS程序。
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引用次数: 0
Multistaged endoscopic full-thickness resection using full-thickness resection device for large recurrent polyp: a case report 内镜下多阶段全层切除应用全层切除装置治疗复发性大息肉1例
Pub Date : 2025-12-01 DOI: 10.1016/j.igie.2025.08.008
Taylor Bowler DO , Natalie Wilson MD , Rahul Karna MD , Mohammad Bilal MD
Endoscopic full-thickness resection (EFTR) using the full-thickness resection device (FTRD) (Ovesco Endoscopy AG, Tübingen, Germany) is an endoscopic technique for management of recurrent polyps up to 30 mm in size. However, data are currently limited on the use of multistaged piecemeal EFTR using the FTRD for larger recurrent and fibrotic polyps. Herein, we present the case of an 85-year-old man referred to advanced endoscopy for a 60-mm recurrent polyp adjacent to the ileocecal valve. The decision was made to perform piecemeal EFTR using the FTRD in a multistaged fashion because of its large size, technically challenging location, and multiple recurrences despite use of different resection modalities. A total of 3 colonoscopies with EFTR using the FTRD were performed with successful removal of the recurrent polyp. Our case report demonstrates that multistaged EFTR using the FTRD can be safe and effective for large polyps in anatomically difficult locations not amenable to conventional resection modalities.
使用全层切除装置(FTRD) (Ovesco Endoscopy AG, t宾根,德国)的内镜下全层切除(EFTR)是一种用于治疗30mm大小的复发性息肉的内镜技术。然而,目前关于多阶段分段EFTR使用FTRD治疗较大复发性和纤维化性息肉的数据有限。在此,我们报告一例85岁的男性患者,因回盲瓣附近60毫米的复发性息肉接受了高级内窥镜检查。由于FTRD体积大,位置技术上具有挑战性,尽管采用了不同的切除方式,但仍有多次复发,因此决定采用FTRD进行分段EFTR。使用FTRD进行EFTR结肠镜检查共3次,成功切除复发息肉。我们的病例报告表明,使用FTRD的多阶段EFTR可以安全有效地治疗解剖困难部位的大息肉,而传统的切除方式无法适应。
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引用次数: 0
Development of an artificial intelligence model to identify duodenal polyps in patients with familial adenomatous polyposis 家族性腺瘤性息肉病患者十二指肠息肉的人工智能识别模型的建立
Pub Date : 2025-12-01 DOI: 10.1016/j.igie.2025.09.009
Daniel Schupack MD, Shubham Sood MD, Jeffrey Fetzer MS, Shradha Shalini MS, Shivaram P. Arunachalam PhD, John B. League MMIS, Cadman Leggett MD, Lisa Boardman MD, Nayantara Coelho-Prabhu MBBS

Background and Aims

Precancerous duodenal polyps can be subtle in familial adenomatous polyposis (FAP). Artificial intelligence models can detect gastrointestinal (GI) tract pathology; thus, we aimed to develop a model to identify duodenal polyps in FAP patients.

Methods

Images of duodenal polyps from upper GI endoscopic surveillance in FAP patients were obtained. Polyps were manually annotated (Label Studio; HumanSignal, San Francisco, Calif, USA), and the nnU-Net framework (Applied Computer Vision Lab of Helmholtz Imaging and the Division of Medical Image Computing at the German Cancer Research Center, Heidelberg, Germany) was used to automate polyp segmentation. Images were randomly divided into training, validation, and test sets (80%, 10%, and 10%, respectively). Primary performance metric was Dice coefficient (score 0-1). Manual counting was also used to compare the model's ability to identify polyps.

Results

Mean polyps per image by manual count was 4.2 (standard deviation [SD] = 4.8) and by prediction model 4.0 (SD = 4.7). Sixty of 87 images (69.0%) had 0 missed polyps, 74 of 87 (85.1%) missed a maximum of 1 polyp, and 83 of 87 (95.4%) missed a maximum of 4. Mean missed polyps per image was 0.9 (SD = 2.3), and the model identified 287 of 365 (78.6%) polyps. Forty of 87 (46.0%) had falsely identified polyps (mean 0.8; SD = 1.0). Missed polyps were smaller than identified polyps (mean 73.3 [SD = 45.3] versus 233.5 [SD = 274.5] pixel diameter, respectively). There was a complete match (no missed or false positive) in 33 of 87 images (37.9%). Dice coefficient was 0.73.

Conclusions

A model to identify duodenal polyps in FAP was successfully created. Although the Dice coefficient is modest compared with that of colon polyp models, duodenal anatomy creates a challenging background for human and computer detection. Rate of polyp detection, likely a superior marker of goal achievement, was >75%, with a low false polyp rate (mean <1/image). This prototype model is the first step toward a refined algorithm to assist in identification of duodenal polyps with a need for larger prospective studies.
背景和目的家族性腺瘤性息肉病(FAP)中发生的十二指肠癌性息肉可能是不易察觉的。人工智能模型可以检测胃肠道病理;因此,我们的目标是建立一个模型来识别FAP患者的十二指肠息肉。方法对FAP患者进行上消化道内镜下十二指肠息肉的影像学检查。对息肉进行人工标注(Label Studio; HumanSignal, San Francisco, california, USA),并使用nnU-Net框架(德国海德堡德国癌症研究中心亥姆霍兹成像应用计算机视觉实验室和医学图像计算部门)对息肉进行自动分割。图像随机分为训练集、验证集和测试集(分别为80%、10%和10%)。主要性能指标是Dice系数(得分0-1)。人工计数也被用来比较模型识别息肉的能力。结果人工计数每张图像平均息肉数为4.2个(标准差[SD] = 4.8),预测模型平均息肉数为4.0个(SD = 4.7)。87张影像中有60张(69.0%)未发现息肉0个,74张(85.1%)未发现息肉最多1个,83张(95.4%)未发现息肉最多4个。每张图像平均遗漏的息肉为0.9 (SD = 2.3), 365个息肉中模型识别出287个(78.6%)。87例中有40例(46.0%)误诊为息肉(平均0.8;SD = 1.0)。未发现的息肉小于已发现的息肉(平均直径分别为73.3 [SD = 45.3]和233.5 [SD = 274.5]像素)。87张图像中有33张(37.9%)完全匹配(无漏报或假阳性)。骰子系数为0.73。结论成功建立了FAP十二指肠息肉模型。虽然Dice系数与结肠息肉模型相比是适度的,但十二指肠解剖为人类和计算机检测创造了一个具有挑战性的背景。息肉检出率为75%,可能是目标实现的优越标志,假息肉率较低(平均1/图像)。这个原型模型是向一个精细的算法的第一步,以协助识别十二指肠息肉,需要更大的前瞻性研究。
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引用次数: 0
Inspection time during colonoscopy withdrawal as measured by a second-generation artificial intelligence program 第二代人工智能程序测量结肠镜检查退出期间的检查时间
Pub Date : 2025-12-01 DOI: 10.1016/j.igie.2025.05.005
Rachel E. Lahr BA, Jackson A. Gallagher BS, Jeremiah Shultz BS, John J. Guardiola MD, Douglas K. Rex MD

Background and Aims

Withdrawal time (WT) is a recommended quality measure for colonoscopy and is associated with adenoma detection and cancer prevention in retrospective studies. WT is intended to measure the time spent searching the colon for polyps but includes the time spent washing, suctioning, taking biopsy samples, and inspecting and resecting colon polyps. ColonPro (Medtronic; Minneapolis, Minn, USA) is a second-generation artificial intelligence (AI) program that reports inspection time (IT). We sought to determine whether the IT reported by ColonPro reflects the actual time searching for polyps.

Methods

We prospectively recorded the procedure time, WT, and IT measured by ColonPro in 100 colonoscopies performed by 11 endoscopists at 2 centers. A trained research assistant measured IT manually with a stopwatch.

Results

Total procedure time and WT were similar when measured manually or by the AI program. AI-measured IT was 2.1 minutes longer than the actual stopwatch-measured IT (9.6 [2.8] vs 7.4 [2.6] minutes, P < .01). The AI-measured IT was longer for all endoscopists and for procedures with or without polypectomy.

Conclusions

Actual IT is not accurately measured by a new commercially available AI program.
背景和目的在回顾性研究中,撤退时间(WT)是结肠镜检查推荐的质量指标,与腺瘤检测和癌症预防相关。WT旨在测量寻找结肠息肉所花费的时间,但包括洗涤,抽吸,活检样本以及检查和切除结肠息肉所花费的时间。ColonPro(美敦力公司,明尼阿波利斯,明尼苏达州,美国)是第二代人工智能(AI)程序,可以报告检查时间(IT)。我们试图确定ColonPro报告的IT是否反映了搜索息肉的实际时间。方法前瞻性记录11名内镜医师在2个中心进行的100例结肠镜检查的手术时间、WT和IT。一位训练有素的研究助理用秒表手动测量IT。结果人工或人工智能程序测量的总过程时间和WT相似。ai测量的IT比实际秒表测量的IT长2.1分钟(9.6 [2.8]vs 7.4[2.6]分钟,P < 0.01)。人工智能测量的IT在所有内窥镜医师和息肉切除或不切除手术中都更长。结论:实际的IT并不能通过新的商业人工智能程序来准确衡量。
{"title":"Inspection time during colonoscopy withdrawal as measured by a second-generation artificial intelligence program","authors":"Rachel E. Lahr BA,&nbsp;Jackson A. Gallagher BS,&nbsp;Jeremiah Shultz BS,&nbsp;John J. Guardiola MD,&nbsp;Douglas K. Rex MD","doi":"10.1016/j.igie.2025.05.005","DOIUrl":"10.1016/j.igie.2025.05.005","url":null,"abstract":"<div><h3>Background and Aims</h3><div>Withdrawal time (WT) is a recommended quality measure for colonoscopy and is associated with adenoma detection and cancer prevention in retrospective studies. WT is intended to measure the time spent searching the colon for polyps but includes the time spent washing, suctioning, taking biopsy samples, and inspecting and resecting colon polyps. ColonPro (Medtronic; Minneapolis, Minn, USA) is a second-generation artificial intelligence (AI) program that reports inspection time (IT). We sought to determine whether the IT reported by ColonPro reflects the actual time searching for polyps.</div></div><div><h3>Methods</h3><div>We prospectively recorded the procedure time, WT, and IT measured by ColonPro in 100 colonoscopies performed by 11 endoscopists at 2 centers. A trained research assistant measured IT manually with a stopwatch.</div></div><div><h3>Results</h3><div>Total procedure time and WT were similar when measured manually or by the AI program. AI-measured IT was 2.1 minutes longer than the actual stopwatch-measured IT (9.6 [2.8] vs 7.4 [2.6] minutes, <em>P</em> &lt; .01). The AI-measured IT was longer for all endoscopists and for procedures with or without polypectomy.</div></div><div><h3>Conclusions</h3><div>Actual IT is not accurately measured by a new commercially available AI program.</div></div>","PeriodicalId":100652,"journal":{"name":"iGIE","volume":"4 4","pages":"Pages 322-324"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145772041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
On behalf of our editors, authors, and readers: a tribute to our reviewers 我谨代表我们的编辑、作者和读者:向我们的审稿人致敬
Pub Date : 2025-12-01 DOI: 10.1016/j.igie.2025.10.017
{"title":"On behalf of our editors, authors, and readers: a tribute to our reviewers","authors":"","doi":"10.1016/j.igie.2025.10.017","DOIUrl":"10.1016/j.igie.2025.10.017","url":null,"abstract":"","PeriodicalId":100652,"journal":{"name":"iGIE","volume":"4 4","pages":"Page 400"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145772036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Novel endoscopic cryoprobe extraction of acute food bolus impaction: a case report 新型内镜冷冻探针提取急性食物丸嵌塞1例报告
Pub Date : 2025-12-01 DOI: 10.1016/j.igie.2025.07.006
Michaela Henderson MD , Nicole Du MD , Lori A. Zimmerman MD , Jessica Yasuda MD , Denis Chang MD, MS , Gary Visner DO , Peter D. Ngo MD
Acute food bolus impaction is frequently encountered in pediatric patients with underlying esophageal conditions. Traditional endoscopic methods for removing friable boluses, such as meat, are often time-intensive and challenging. This report explores the novel application of cryoadhesion, or freezing and adhering an object to a cryoprobe, for esophageal meat bolus extraction. A 25-year-old man with trisomy 21 and eosinophilic esophagitis presented with acute food bolus impaction. After unsuccessful conventional endoscopic maneuvers, a cryoprobe was externally attached to an endoscope and used to achieve cryoadhesion and extraction of the meat bolus. Within 10 minutes, the meat bolus was successfully removed attached to the cryoprobe without mucosal injury. The patient tolerated the procedure well and was discharged the next day without adverse events. Cryoadhesion via a flexible cryoprobe may offer a feasible alternative for removing challenging food impactions. Further investigation is warranted to evaluate its safety and efficacy.
急性食物丸嵌塞是经常遇到的儿童患者潜在的食道疾病。传统的内窥镜切除易碎物质(如肉)的方法通常耗时且具有挑战性。本报告探讨了冷冻粘连的新应用,或冷冻并粘附物体到冷冻探针上,用于食道肉丸提取。一个25岁的男性21三体和嗜酸性食管炎提出急性食物丸嵌塞。在常规内窥镜操作失败后,将冷冻探针连接到内窥镜外部,用于实现肉丸的冷冻粘附和提取。在10分钟内,肉丸被成功地取出,并附着在低温探针上,没有粘膜损伤。患者对手术耐受良好,并于次日出院,无不良事件发生。通过柔性冷冻探针的低温粘附可以为去除具有挑战性的食物嵌塞提供可行的选择。需要进一步的研究来评估其安全性和有效性。
{"title":"Novel endoscopic cryoprobe extraction of acute food bolus impaction: a case report","authors":"Michaela Henderson MD ,&nbsp;Nicole Du MD ,&nbsp;Lori A. Zimmerman MD ,&nbsp;Jessica Yasuda MD ,&nbsp;Denis Chang MD, MS ,&nbsp;Gary Visner DO ,&nbsp;Peter D. Ngo MD","doi":"10.1016/j.igie.2025.07.006","DOIUrl":"10.1016/j.igie.2025.07.006","url":null,"abstract":"<div><div>Acute food bolus impaction is frequently encountered in pediatric patients with underlying esophageal conditions. Traditional endoscopic methods for removing friable boluses, such as meat, are often time-intensive and challenging. This report explores the novel application of cryoadhesion, or freezing and adhering an object to a cryoprobe, for esophageal meat bolus extraction. A 25-year-old man with trisomy 21 and eosinophilic esophagitis presented with acute food bolus impaction. After unsuccessful conventional endoscopic maneuvers, a cryoprobe was externally attached to an endoscope and used to achieve cryoadhesion and extraction of the meat bolus. Within 10 minutes, the meat bolus was successfully removed attached to the cryoprobe without mucosal injury. The patient tolerated the procedure well and was discharged the next day without adverse events. Cryoadhesion via a flexible cryoprobe may offer a feasible alternative for removing challenging food impactions. Further investigation is warranted to evaluate its safety and efficacy.</div></div>","PeriodicalId":100652,"journal":{"name":"iGIE","volume":"4 4","pages":"Pages 359-361"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145772030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Master of innovation: unlocking creativity in the development of novel solutions from interventional endoscopy to neurogastroenterology 创新大师:在从介入内窥镜到神经胃肠病学的新解决方案的开发中释放创造力
Pub Date : 2025-12-01 DOI: 10.1016/j.igie.2025.09.014
P.Jay Pasricha MBBS, MD, MASGE , Phillip S. Ge MD, FASGE
{"title":"Master of innovation: unlocking creativity in the development of novel solutions from interventional endoscopy to neurogastroenterology","authors":"P.Jay Pasricha MBBS, MD, MASGE ,&nbsp;Phillip S. Ge MD, FASGE","doi":"10.1016/j.igie.2025.09.014","DOIUrl":"10.1016/j.igie.2025.09.014","url":null,"abstract":"","PeriodicalId":100652,"journal":{"name":"iGIE","volume":"4 4","pages":"Pages 369-383"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145772033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Randomized crossover trial comparing through-the-scope balloon enteroscopy via colonoscope with standard colonoscopy on depth of ileal insertion 随机交叉试验比较经结肠镜与标准结肠镜对回肠插入深度的影响
Pub Date : 2025-09-01 DOI: 10.1016/j.igie.2025.06.002
M. Ammar Kalas MD , Luis O. Chavez MD , Ihsan Al-Bayati MD , Nancy Casner MS , Alok K. Dwivedi PhD , Sherif E. Elhanafi MD , Marc J. Zuckerman MD

Background and Aims

Retrograde enteroscopy for evaluation of the small bowel can be performed using through-the-scope balloon-assisted enteroscopy (TTSE). TTSE consists of a balloon catheter designed for anchoring in the small bowel, inserted through the instrument channel of a standard colonoscope. We aimed to assess the ability of TTSE to improve the depth of maximal ileal insertion (DMI) compared with the colonoscope alone (C1).

Methods

We performed a prospective, randomized, crossover study to compare the DMI between TTSE and enteroscopy using the adult colonoscope alone. After measuring the DMI by the randomized sequence, the endoscopist switched the technique and measured the DMI again. The primary end point of the study was a comparison of DMI (centimeters) between the colonoscope with TTSE (DMI-N) and the colonoscope alone (DMI-C).

Results

A total of 18 subjects were enrolled, with 9 randomized to colonoscope alone first (C1) followed by TTSE (N2) and 9 to TTSE first (N1) followed by colonoscope alone (C2). The mean (standard deviation) of DMI was DMI-C1: 69.4 (40.3), DMI-N2: 107.2 (62.4), DMI-N1: 92.2 (31.3), and DMI-C2: 102.8 (29.1). Overall, TTSE showed a trend toward an increased DMI compared with the colonoscope alone (difference = 13.61; 95% confidence interval, −3.12 to 30.34; P = .06). In the stratified analyses by the randomization sequence (ie, C1N2), TTSE produced a significant increase in DMI (difference = 37.8; 95% confidence interval, 14.08-61.48; P = .006) compared with the colonoscope alone.

Conclusions

As per design-based analysis, the TTSE technique produced an increased DMI ranging between 13.6 and 37.8 cm more than with the standard colonoscope, which trended toward significance. Retrograde enteroscopy using TTSE may help improve DMI compared with colonoscope alone.
背景和目的逆行小肠镜检查小肠的评估可以使用经镜气囊辅助小肠镜检查(TTSE)。TTSE包括设计用于锚定小肠的球囊导管,通过标准结肠镜的仪器通道插入。我们的目的是评估与单独结肠镜相比,TTSE提高最大回肠插入深度(DMI)的能力(C1)。方法我们进行了一项前瞻性、随机、交叉研究,比较TTSE和单独使用成人结肠镜的肠镜检查的DMI。在随机顺序测量DMI后,内窥镜医师改变技术并再次测量DMI。该研究的主要终点是比较TTSE结肠镜(DMI- n)和单独结肠镜(DMI- c)的DMI(厘米)。结果共纳入18例受试者,其中9例随机分为先行结肠镜检查(C1)后行TTSE检查(N2)组和先行TTSE检查(N1)后行结肠镜检查(C2)组。DMI的均值(标准差)为DMI- c1: 69.4 (40.3), DMI- n2: 107.2 (62.4), DMI- n1: 92.2 (31.3), DMI- c2: 102.8(29.1)。总体而言,与单独结肠镜检查相比,TTSE有增加DMI的趋势(差异= 13.61;95%可信区间,−3.12 ~ 30.34;P = 0.06)。在随机化序列(即C1N2)的分层分析中,与单独结肠镜相比,TTSE使DMI显著增加(差异= 37.8;95%可信区间为14.08-61.48;P = 0.006)。结论根据设计分析,与标准结肠镜相比,TTSE技术产生的DMI增加了13.6 ~ 37.8 cm,具有显著性趋势。与单独结肠镜相比,使用TTSE的逆行肠镜检查可能有助于改善DMI。
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引用次数: 0
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