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A comparative study on transnasal gastroscopy and conventional gastroscopy for percutaneous endoscopic pancreatic necrosectomy 经鼻胃镜与常规胃镜在经皮内镜胰腺坏死切除术中的比较研究
Pub Date : 2019-11-20 DOI: 10.3760/CMA.J.ISSN.1007-5232.2019.11.005
Yuan-hang Dong, Chun-ying Jiang, W. Guo, Yanbo Zeng, Yiqi Du
Objective To compare the therapeutic value of transnasal gastroscopy and conventional gastroscopy for infective pancreatic necrosis(IPN) through percutaneous endoscopic necrosectomy(PEN). Methods A total of 24 IPN patients who received PEN for IPN from December 2015 to March 2019 were divided into the conventional gastroscopy group (n=15) and the transnasal gastroscopy group (n=9). The clinical therapeutic indicators such as vital signs, APACHE Ⅱ score changes, operation duration, difference in preoperative and postoperative volumes of peripancreatic necrosis and other indicators were compared between the two groups. Results There was no significant difference in the variation curve fitting of APACHE Ⅱ scores between the two groups (t=0.378, P=0.710). The operation time of the transnasal gastroscopy group was significantly shorter than that of the conventional gastroscopy group (119.7±47.4 min VS 172.8±56.2 min, P=0.018). Peripancreatic necrotic volume significantly decreased after operation in the transnasal gastroscopy group (404.03±170.73 mL VS 468.9±137.37 mL, P=0.002), and in the conventional gastroscopy group (499.44±227.17 mL VS 722.50±292.96 mL, P<0.001). There was no significant difference in the decrease extent in the conventional gastroscopy group and the transnasal gastroscopy group (223.06±212.92 mL VS 64.87±54.94 mL, P= 0.094). Conclusion On the condition of poor drainage of percutaneous catheter drainage, PEN can significantly reduce the range of necrotic lesions. Transnasal gastroscopy has the advantages in operation time in PEN and clearing deep abscess cavities over conventional gastroscopy. Key words: Pancreatitis; Percutaneous endoscopic necrosectomy; Infective pancreatic necrosis
目的比较经皮内镜下坏死切除术(PEN)经鼻胃镜与常规胃镜对感染性胰腺坏死(IPN)的治疗价值。方法将2015年12月至2019年3月接受PEN治疗的24例IPN患者分为常规胃镜组(n=15)和经鼻胃镜组(n=9)。比较两组患者的生命体征、APACHEⅡ评分变化、手术时间、术前和术后胰周坏死量的差异等临床治疗指标。结果两组APACHEⅡ评分变化曲线拟合无显著性差异(t=0.378,P=0.710),经鼻胃镜检查组手术时间明显短于常规胃镜检查组(119.7±47.4min VS 172.8±56.2min,P=0.018)经鼻胃镜检查组(404.03±170.73mL VS 468.9±137.37mL,P=0.002),常规胃镜检查组(499.44±227.17 mL VS 722.50±292.96 mL,P<0.001)。常规胃镜检查和经鼻胃镜检查组的下降幅度(223.06±212.92 mL VS 64.87±54.94 mL,P=0.094)无显著差异,PEN可以显著减少坏死病变的范围。与传统胃镜相比,经鼻胃镜在PEN手术时间和清除深脓肿腔方面具有优势。关键词:胰腺炎;经皮内镜尸检;感染性胰腺坏死
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引用次数: 1
A prospective study of optical coherence tomography for predicting invasion depth of early esophageal cancer 光学相干断层扫描预测早期食管癌侵袭深度的前瞻性研究
Pub Date : 2019-11-20 DOI: 10.3760/CMA.J.ISSN.1007-5232.2019.11.002
J. Xiang, E. Linghu, Longsong Li, Xiangyao Wang, J. Zou, H. Du, Ping Tang, N. Chai
Objective To evaluate optical coherence tomography(OCT)for predicting invasion depth of early esophageal cancer(EEC) and to compare OCT and magnifying endoscopy-narrow band imaging (ME-NBI)in clinical performance. Methods Twenty-eight patients who were diagnosed with EEC and accepted OCT and ME-NBI before endoscopic submucosal dissection(ESD)were enrolled in this prospective study. On the basis of OCT and ME-NBI images, real-time prediction of EEC invasion depth was conducted. Postoperative pathological results were taken as golden standard to compare the accuracy of OCT and ME-NBI in evaluation of EEC invasion depth. The procedure time and incidence of complications during evaluation process were also analyzed. Results The overall accuracy of OCT and ME-NBI in predicting invasion depth of 28 EEC patients were 67.9% (19/28) and 75.0% (21/28) respectively, with no significant difference(P>0.05). The accuracy of OCT and ME-NBI in distinguishing lesions located in epithelium/lamina propria mucosa (EP/LPM) lesions were 78.9%(15/19) and 68.4% (13/19), with no significant difference(P>0.05). The procedure time of OCT was significantly shorter than that of ME-NBI (6.0±2.9 min VS 16.3±5.4 min, P<0.001). Conclusion The ability of OCT to predict invasion depth of EEC and distinguish lesions located in the EP/LPM is comparable with that of ME-NBI. Besides, OCT requires shorter procedure time for evaluation. Key words: Tomography, optical coherence; Esophageal neoplasm; Invasion depth; Magnifying endoscopy with narrow band imaging; Accuracy
目的探讨光学相干断层扫描(OCT)对早期食管癌(EEC)侵袭深度的预测价值,并比较OCT与放大内镜-窄带成像(ME-NBI)的临床应用价值。方法28例经内镜下粘膜下剥离术(ESD)前诊断为EEC并接受OCT和ME-NBI检查的患者进行前瞻性研究。在OCT和ME-NBI图像的基础上,实时预测脑电图侵袭深度。以术后病理结果为金标准,比较OCT与ME-NBI评价脑电图侵袭深度的准确性。并分析了手术时间和评估过程中并发症的发生率。结果OCT和ME-NBI预测28例脑电图患者侵深的总体准确率分别为67.9%(19/28)和75.0%(21/28),两者差异无统计学意义(P < 0.05)。OCT与ME-NBI区分上皮/固有层粘膜(EP/LPM)病变的准确率分别为78.9%(15/19)和68.4%(13/19),差异无统计学意义(P < 0.05)。OCT的手术时间明显短于ME-NBI(6.0±2.9 min VS 16.3±5.4 min, P<0.001)。结论OCT预测脑电图侵袭深度和区分EP/LPM病变的能力与ME-NBI相当。此外,OCT需要更短的程序时间进行评估。关键词:层析成像;光学相干;食管肿瘤;侵入深度;窄带放大内镜;精度
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引用次数: 0
Clinical value of repeated peroral endoscopic myotomy for persistent/recurrent achalasia 反复经口内镜下肌切开术治疗持续性/复发性贲门失弛缓症的临床价值
Pub Date : 2019-11-20 DOI: 10.3760/CMA.J.ISSN.1007-5232.2019.11.003
Gen Huang, Quanlin Li, P. Zhou
Objective To evaluate the feasibility, safety and efficacy of repeated peroral endoscopic myotomy (Re-POEM) as a make-up therapy after POEM failure. Methods Thirty-three patients with persistent/recurrent symptoms after first POEM (Eckardt symptom score≥4) were selected from a database of a total of 2 516 consecutive patients with achalasia. The main outcome measures was Eckardt score during follow-up; the secondary outcome measures were procedure-related adverse events, changes in manometric lower esophageal sphincter (LES) pressure, and reflux symptoms before and after Re-POEM. Results All patients successfully underwent Re-POEM in mean 18.6 months (ranging 3-55 months) after their first POEM procedures. The mean symptom score before Re-POEM was 5.5 (ranging 4-8). Mean operation time was 45.1 minutes (ranging 28-64 minutes). Submucosal tunnel infection occurred in 1 patient who recovered with conservative treatment. During a mean follow-up period of 36.6 months (ranging 12-58 months), symptom relief was achieved in all patients. Eckardt score reduced to 1.3 (ranging 0-3), significantly different from that before (P<0.001). Mean LES pressure also declined from 26.0 mmHg (1 mmHg=0.133 kPa) to 9.6 mmHg after Re-POEM (P<0.001). The incidence of gastroesophageal reflux of Re-POEM was 33.3% (11/33). Conclusions Re-POEM appears safe and effective as a make-up option after POEM failure. Key words: Esophageal achalasia; Peroral endoscopic myotomy; Repeated peroral endoscopic myotomy
目的探讨经口反复内镜下肌切开术(Re-POEM)作为手术失败后补足治疗的可行性、安全性和有效性。方法从连续2 516例贲门失弛缓症患者数据库中选择33例首次POEM后出现持续/复发症状(Eckardt症状评分≥4)的患者。随访时主要结局指标为Eckardt评分;次要结局指标为手术相关不良事件、食管下括约肌(LES)压力的变化以及Re-POEM前后的反流症状。结果所有患者在第一次POEM术后平均18.6个月(3-55个月)成功行二次POEM。Re-POEM前的平均症状评分为5.5分(范围4-8分)。平均手术时间45.1分钟(28 ~ 64分钟)。1例患者发生粘膜下隧道感染,经保守治疗后痊愈。在平均36.6个月(12-58个月)的随访期间,所有患者的症状均得到缓解。Eckardt评分降至1.3(范围0-3),与治疗前比较差异有统计学意义(P<0.001)。Re-POEM术后平均LES压也从26.0 mmHg (1 mmHg=0.133 kPa)降至9.6 mmHg (P<0.001)。Re-POEM胃食管反流发生率为33.3%(11/33)。结论:Re-POEM作为POEM失败后的补充选择是安全有效的。关键词:食道失弛缓症;经口内窥镜肌切开术;反复经口内窥镜肌切开术
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引用次数: 0
Magnetic tracer technique in laparoscopic localization for gastrointestinal lesions 磁示踪技术在腹腔镜胃肠病变定位中的应用
Pub Date : 2019-11-20 DOI: 10.3760/CMA.J.ISSN.1007-5232.2019.11.006
M. Ren, Feng Ma, Xuejun Sun, Xiaopeng Yan, Wei Zhao, Jianbao Zheng, Wenhui Ma, Xinlan Lu, Shuixiang He, G. Lu
Objective To evaluate the feasibility and safety of magnetic tracer technique for preoperative endoscopic marking in laparoscopic surgery. Methods In the preliminary study, a total of 8 patients with gastric (n=3) or colorectal (n=5) tumors underwent endoscopic magnetic marking before laparoscopic surgery from April to June in 2019. First, a magnet was attached to the lesion by 2 titanium clips under the endoscope. Second, during the subsequent laparoscopic operations, the other magnet was sent to the vicinity of the lesion through the laparoscopic tunnel. The magnet in the abdominal cavity was quickly attracted to the one in the gastrointestinal tract to successfully locate the lesions. Data of preoperative marking and operations of 8 patients were reviewed. Results All 8 lesions were marked successfully, rapid and accurate intraoperative positioning was achieved. The mean time of endoscopic marking was 5.75±2.45 minutes, and the mean time of intraoperative localization was 1.94±0.56 minutes. All patients underwent laparoscopic tumor resections with accurate localization. The mean proximal and distal resection margins of colorectal tumors were 105 mm and 74 mm respectively. No complications occurred. Conclusion Magnetic tracer technique for laparoscopic localization, simple, safe and accurate for gastrointestinal lesions, can be performed without additional equipment or endoscopic procedures involved. Key words: Gastrointestinal tract; Laparoscopes; Orientation; Magnet
目的评价磁示踪技术在腹腔镜手术中用于术前内镜标记的可行性和安全性。方法在初步研究中,2019年4月至6月,共有8名胃肿瘤(n=3)或结直肠癌(n=5)患者在腹腔镜手术前接受了内镜磁标记。首先,通过内窥镜下的2个钛夹将磁铁固定在病变处。其次,在随后的腹腔镜手术中,另一块磁铁通过腹腔镜隧道被送到病变附近。腹腔中的磁铁很快被吸引到胃肠道中的磁铁上,成功定位了病变。回顾了8例患者的术前标记和手术资料。结果8个病灶均成功标记,术中定位快速准确。内镜标记平均时间为5.75±2.45分钟,术中定位平均时间为1.94±0.56分钟。所有患者均接受了精确定位的腹腔镜肿瘤切除术。结直肠肿瘤的平均近端和远端切除边缘分别为105mm和74mm。无并发症发生。结论磁示踪技术用于腹腔镜定位胃肠道病变,简单、安全、准确,无需额外的设备或内镜手术。关键词:胃肠道;腹腔镜;定向;磁铁
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引用次数: 0
Diagnostic value of JNET classification under narrow-band imaging for colorectal laterally spreading tumors 窄带成像下JNET分型对结直肠横向扩散肿瘤的诊断价值
Pub Date : 2019-10-20 DOI: 10.3760/CMA.J.ISSN.1007-5232.2019.10.003
Zihua Wang, Jie Yu, Shiying Yang
Objective To evaluate the diagnostic efficacy of Japan Narrow Band Imaging Expert Team(JNET) classification under narrow-band imaging (NBI) for colorectal laterally spreading tumors. Methods Data of 170 laterally spreading tumors (LST) detected by NBI and pigment dyeing were reviewed in the retrospective study. JNET classification under NBI was used for rediagnosis based on surface pattern and vessel pattern. Pit pattern(PP) was observed under pigment dyeing using PP classification. The results were compared with histologic results after endoscopic resection or surgery. Results The diagnostic sensitivity, specificity, positive predictive value, negative predictive value and accuracy of JNET classification and PP classification were 92.2% VS 70.3%, 82.3% VS 85.0%, 74.7% VS 72.6%, 94.9% VS 83.5%, 85.9% VS 79.7%, respectively (P=0.159). The consistency rates of JNET classification and PP classification in predicting shallow invasion depth of LST were 6.1% and 8.3% respectively and the consistency rates in predicting deep invasion were 30.8% and 4.8%, respectively. Conclusion JNET classification under NBI is effective in predicting malignant laterally spreading tumors, however, its efficacy in predicting tumor invasion depth is unsatisfied. PP classification can be used to improve the diagnostic accuracy for those with diagnostic difficulty. Key words: Colorectal neoplasms; Diagnosis; Laterally spreading tumor; Narrow-band imaging; JNET classification
目的评价日本窄带成像专家组(JNET)在窄带成像(NBI)下对结直肠癌横向扩散肿瘤的诊断效果。方法回顾性分析170例经NBI和色素染色检测的横向扩散性肿瘤(LST)的临床资料。NBI下的JNET分类用于基于表面模式和血管模式的再诊断。使用PP分类法在颜料染色下观察到凹坑图案(PP)。将结果与内镜切除或手术后的组织学结果进行比较。结果JNET分型和PP分型的诊断敏感性、特异性、阳性预测值、阴性预测值和准确性分别为92.2%和70.3%、82.3%和85.0%、74.7%和72.6%、94.9%和83.5%、85.9%和79.7%,JNET分类和PP分类预测LST浅层入侵深度的一致性分别为6.1%和8.3%,预测深层入侵的一致性则分别为30.8%和4.8%。结论NBI下的JNET分类对预测恶性横向扩散肿瘤是有效的,但对预测肿瘤浸润深度的效果并不理想。PP分类可用于提高诊断困难患者的诊断准确性。关键词:结直肠肿瘤;诊断;横向扩散肿瘤;窄带成像;JNET分类
{"title":"Diagnostic value of JNET classification under narrow-band imaging for colorectal laterally spreading tumors","authors":"Zihua Wang, Jie Yu, Shiying Yang","doi":"10.3760/CMA.J.ISSN.1007-5232.2019.10.003","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-5232.2019.10.003","url":null,"abstract":"Objective \u0000To evaluate the diagnostic efficacy of Japan Narrow Band Imaging Expert Team(JNET) classification under narrow-band imaging (NBI) for colorectal laterally spreading tumors. \u0000 \u0000 \u0000Methods \u0000Data of 170 laterally spreading tumors (LST) detected by NBI and pigment dyeing were reviewed in the retrospective study. JNET classification under NBI was used for rediagnosis based on surface pattern and vessel pattern. Pit pattern(PP) was observed under pigment dyeing using PP classification. The results were compared with histologic results after endoscopic resection or surgery. \u0000 \u0000 \u0000Results \u0000The diagnostic sensitivity, specificity, positive predictive value, negative predictive value and accuracy of JNET classification and PP classification were 92.2% VS 70.3%, 82.3% VS 85.0%, 74.7% VS 72.6%, 94.9% VS 83.5%, 85.9% VS 79.7%, respectively (P=0.159). The consistency rates of JNET classification and PP classification in predicting shallow invasion depth of LST were 6.1% and 8.3% respectively and the consistency rates in predicting deep invasion were 30.8% and 4.8%, respectively. \u0000 \u0000 \u0000Conclusion \u0000JNET classification under NBI is effective in predicting malignant laterally spreading tumors, however, its efficacy in predicting tumor invasion depth is unsatisfied. PP classification can be used to improve the diagnostic accuracy for those with diagnostic difficulty. \u0000 \u0000 \u0000Key words: \u0000Colorectal neoplasms; Diagnosis; Laterally spreading tumor; Narrow-band imaging; JNET classification","PeriodicalId":10072,"journal":{"name":"Chinese Journal of Digestive Endoscopy","volume":"36 1","pages":"725-730"},"PeriodicalIF":0.0,"publicationDate":"2019-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44265228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of general anesthesia maintenance without muscle relaxants for double-balloon enteroscopy: a randomized controlled trial 无肌肉松弛剂全麻维持对双气囊肠镜检查的影响:一项随机对照试验
Pub Date : 2019-10-20 DOI: 10.3760/CMA.J.ISSN.1007-5232.2019.10.008
Xiaoping Xia, E. Wang
Objective To evaluate the feasibility and safety of maintaining general anesthesia without neuromuscular blockade in oral double-balloon enteroscopy. Methods Totally 120 patients undergoing oral double-balloon enteroscopy under general anesthesia were randomly assigned into two groups: the observation group and the control group. The observation group was not given muscle relaxants for anesthesia maintenance, while the control group was given muscle relaxants punctually. Observation indexes were monitored, including the mean arterial pressure (MAP), heart rate (HR), peak airway pressure (Ppeak) and end-tidal CO2 partial pressure (PETCO2) before anesthesia (T0), immediately after intubation (T1), at the time of endoscopy placement (T2), at the end of endoscopy withdrawal (T3), and at the time of waking-up (T4). The cases of spontaneous breathing recovery before the end of endoscopy, postoperative recovery time, extubation time, length of PACU stay, postoperative adverse reactions and satisfactory rates were recorded. Results Twelve cases were removed by the exclusion criteria, and the remaining 108 cases completed the study, including 56 cases in the observation group and 52 cases in the control group. The one-time success rate of induction was both 100% in the two groups. There were no significant differences in MAP, HR, Ppeak, and PETCO2 between the two groups at each observation point (all P>0.05), and the same is true for within group comparison with T0 (all P>0.05). The recovery rate of spontaneous respiration in the observation group was significantly higher than that in the control group [100% (56/56) VS 42% (22/52), χ2=44.73, P=0.000]. The awaken time, extubation time and length of PACU stay were 6±2 min, 10±3 min, and 11±4 min, respectively, in the observation group, compared with 15±5 min (t=-12.64, P=0.000), 17±5 min (t=-8.90, P=0.000), and 17±7 min (t=-5.73, P=0.000) in the control group. None of the patients required assisted ventilation. Hypoxemia occurred in 2 cases and nausea in 3 cases in the control group, while only nausea occurred in 1 patient in the observation group. The overall incidence of adverse reactions was not statisticaly different between the two groups (P>0.05). Anesthesia satisfaction rate of two groups was 100%. Conclusion It is feasible and safe to perform oral double-balloon enteroscopy without muscle relaxants during maintaining under general anesthesia, with quick recovery of spontaneous breathing and awakening, early extubation and less cost. Key words: Anesthesia, intravenous; Without muscle relaxants; Double-balloon enteroscopy
目的评价口服双气囊肠镜在不使用神经肌肉阻滞的情况下维持全身麻醉的可行性和安全性。方法将120例全麻下经口双气囊肠镜检查的患者随机分为观察组和对照组。观察组未给予肌肉松弛剂维持麻醉,对照组则按时给予肌肉放松剂。监测观察指标,包括麻醉前(T0)、插管后(T1)、放置内窥镜时(T2)、停镜时(T3)和苏醒时(T4)的平均动脉压(MAP)、心率(HR)、气道峰值压力(Ppeak)和潮气末CO2分压(PETCO2)。记录内镜检查结束前自主呼吸恢复的情况、术后恢复时间、拔管时间、PACU停留时间、术后不良反应和满意率。结果12例按排除标准切除,其余108例完成研究,其中观察组56例,对照组52例。两组的一次性诱导成功率均为100%。两组在各观察点的MAP、HR、Ppeak和PETCO2均无显著差异(均P>0.05),组内与T0的比较也无显著差异。观察组自主呼吸恢复率显著高于对照组[100%(56/56)VS 42%(22/52),χ2=44.73,P=0.000],观察组拔管时间和PACU停留时间分别为6±2min、10±3min和11±4min,而对照组分别为15±5min(t=-12.64,P=0.000)、17±5min(t=-8.90,P=0.000。没有一名患者需要辅助通气。对照组出现低氧血症2例,恶心3例,观察组仅出现恶心1例。两组总不良反应发生率差异无统计学意义(P>0.05),两组麻醉满意率均为100%。结论在全麻维持期间,在不使用肌肉松弛剂的情况下进行口服双气囊肠镜检查是可行和安全的,自主呼吸和苏醒恢复快,拔管早,费用低。关键词:麻醉,静脉注射;不含肌肉松弛剂;双气囊肠镜检查
{"title":"Effects of general anesthesia maintenance without muscle relaxants for double-balloon enteroscopy: a randomized controlled trial","authors":"Xiaoping Xia, E. Wang","doi":"10.3760/CMA.J.ISSN.1007-5232.2019.10.008","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-5232.2019.10.008","url":null,"abstract":"Objective \u0000To evaluate the feasibility and safety of maintaining general anesthesia without neuromuscular blockade in oral double-balloon enteroscopy. \u0000 \u0000 \u0000Methods \u0000Totally 120 patients undergoing oral double-balloon enteroscopy under general anesthesia were randomly assigned into two groups: the observation group and the control group. The observation group was not given muscle relaxants for anesthesia maintenance, while the control group was given muscle relaxants punctually. Observation indexes were monitored, including the mean arterial pressure (MAP), heart rate (HR), peak airway pressure (Ppeak) and end-tidal CO2 partial pressure (PETCO2) before anesthesia (T0), immediately after intubation (T1), at the time of endoscopy placement (T2), at the end of endoscopy withdrawal (T3), and at the time of waking-up (T4). The cases of spontaneous breathing recovery before the end of endoscopy, postoperative recovery time, extubation time, length of PACU stay, postoperative adverse reactions and satisfactory rates were recorded. \u0000 \u0000 \u0000Results \u0000Twelve cases were removed by the exclusion criteria, and the remaining 108 cases completed the study, including 56 cases in the observation group and 52 cases in the control group. The one-time success rate of induction was both 100% in the two groups. There were no significant differences in MAP, HR, Ppeak, and PETCO2 between the two groups at each observation point (all P>0.05), and the same is true for within group comparison with T0 (all P>0.05). The recovery rate of spontaneous respiration in the observation group was significantly higher than that in the control group [100% (56/56) VS 42% (22/52), χ2=44.73, P=0.000]. The awaken time, extubation time and length of PACU stay were 6±2 min, 10±3 min, and 11±4 min, respectively, in the observation group, compared with 15±5 min (t=-12.64, P=0.000), 17±5 min (t=-8.90, P=0.000), and 17±7 min (t=-5.73, P=0.000) in the control group. None of the patients required assisted ventilation. Hypoxemia occurred in 2 cases and nausea in 3 cases in the control group, while only nausea occurred in 1 patient in the observation group. The overall incidence of adverse reactions was not statisticaly different between the two groups (P>0.05). Anesthesia satisfaction rate of two groups was 100%. \u0000 \u0000 \u0000Conclusion \u0000It is feasible and safe to perform oral double-balloon enteroscopy without muscle relaxants during maintaining under general anesthesia, with quick recovery of spontaneous breathing and awakening, early extubation and less cost. \u0000 \u0000 \u0000Key words: \u0000Anesthesia, intravenous; Without muscle relaxants; Double-balloon enteroscopy","PeriodicalId":10072,"journal":{"name":"Chinese Journal of Digestive Endoscopy","volume":"36 1","pages":"750-754"},"PeriodicalIF":0.0,"publicationDate":"2019-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47774773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy and safety of endoscopic and laparoscopic treatment for gastric stromal tumor: a meta-analysis 内镜和腹腔镜治疗胃间质瘤的疗效和安全性:一项荟萃分析
Pub Date : 2019-10-20 DOI: 10.3760/CMA.J.ISSN.1007-5232.2019.10.009
Fumei Yin, Fengjun Shen
Objective To systematically evaluate the efficacy and safety of endoscopic resection and laparoscopic surgery for gastrointestinal stromal tumors(GIST) (diameter<3.5 cm). Methods According to the Cocharane system search strategy, Chinese and English literature comparing endoscopic with laparoscopic treatment of GIST published from January 2000 to March 2018 were collected. Ten articles meeting the inclusion criteria were included and analyzed with Revman 5.3. Results Of the 10 articles, 1 was a prospective randomized controlled trial and 9 were retrospective non-randomized controlled trials. The total number of patients was 1 062. There were 732 cases in the endoscopic treatment group, and 330 cases in the laparoscopic surgery group. The meta-analysis results showed that the endoscopic treatment group had shorter operation time (MD=-30.58 min, 95%CI: -39.31--21.84, P<0.05), less blood loss (MD=-12.99 mL, 95%CI: -16.40--9.57, P<0.05), shorter hospital stay (MD=-3.17 d, 95%CI: -4.76--1.59, P<0.05), and less total cost (MD=-1.63 ten thousand RMB, 95%CI: -2.42--0.84, P<0.05) than those of the laparoscopic group. But there were no significant differences in the positive rate of margin(RR=2.35, 95%CI: 0.52-10.69, P=0.27) or perioperative complications(RR=1.08, 95%CI: 0.48-2.42, P=0.85). Conclusion Existing studies have shown that endoscopic treatment for GIST is effective, minimally invasive, economical with better prognosis, ensuring complete resection. Key words: Meta-analysis; Endoscopes; Laparoscopes; Gastric stromal tumor
目的系统评价内镜下切除和腹腔镜手术治疗胃肠道间质瘤(直径<3.5cm)的疗效和安全性。方法根据Cocharane系统检索策略,收集2000年1月至2018年3月发表的中英文文献,比较内镜和腹腔镜治疗GIST。纳入10篇符合纳入标准的文章,并用Revman 5.3进行分析。结果10篇文章中,1篇为前瞻性随机对照试验,9篇为回顾性非随机对照试验。病人总数为1062人。内镜治疗组732例,腹腔镜手术组330例。荟萃分析结果显示,与腹腔镜组相比,内镜治疗组的手术时间更短(MD=30.58min,95%CI:39.31-21.84,P<0.05),出血量更少(MD=12.99mL,95%CI:16.40-9.57,P<0.05)、住院时间更短(MD=-3.17d,95%CI:4.76--1.59,P<0.05)和总费用更少(MD=-1.63万元,95%CI:2.42--0.84,P<0.01)。结论内镜治疗GIST是一种有效、微创、经济、预后良好的方法,可确保手术切除。关键词:荟萃分析;内窥镜;腹腔镜;胃间质瘤
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引用次数: 0
Risk factors of procedure time of endoscopic submucosal dissection for esophageal lesions 食管病变内镜下黏膜下剥离术时间的危险因素
Pub Date : 2019-10-20 DOI: 10.3760/CMA.J.ISSN.1007-5232.2019.10.002
Xiao Li, Min Zhu
Objective To investigate risk factors of procedure time of endoscopic submucosal dissection (ESD) for treatment of esophageal lesions. Methods A total of 160 patients with single esophageal lesion who underwent ESD at department of gastroenterology, Beijing Friendship Hospital from January 2015 to October 2017 were enrolled. Medical information including general information (age and gender), and lesion’s characteristics (location, size, gross morphology, pathological type, differentiation degree, and depth of invasion), operators’experience, circumferential resection size, operation and anesthesia time were retrospectively collected. According to the operation time, the cases were divided into the long-term operation group (exceeded 120 min) and the short-time operation group (less than 120 min). The factors affecting the esophageal ESD operation time were analyzed by univariate and multivariate analysis. Results Among the 160 patients, 120 (75.0%) were men and 40 (25.0%) were women. The age was 62.65±8.48 years. The median (interquartile range) size of lesion was 1.70 (1.00, 2.65) cm. The median time of ESD was 113.54 (81.25, 168.75) min. Univariate analysis showed that age >65 years, the lesions of type Ⅱa+ Ⅱc/Ⅱc, lesion size >2 cm and >1/2 esophageal circumference resection were associated with a longer ESD operation time (P 0.05). Multivariate analysis showed that the type Ⅱa+ Ⅱc/Ⅱc (OR=2.47, 95%CI: 1.01-6.06, P=0.047), lesion size>2 cm (OR=3.41, 95%CI: 1.34-8.64, P=0.010) and > 1/2 esophageal circumference resection (OR=4.24, 95%CI: 1.62-11.11, P=0.030) were independent risk factors for the operation time of longer than 120 min. Conclusion Type Ⅱa+ Ⅱc/Ⅱc lesions, the lesion size >2 cm and the resection area >1/2 esophageal circumference were independent risk factors for a prolonged operation time of esophageal ESD procedure. Key words: Risk factors; Early esophageal cancers; Endoscopic submucosal dissection; Procedure time
目的探讨内镜下粘膜下剥离术(ESD)治疗食管病变手术时间的影响因素。方法选取2015年1月至2017年10月在北京友谊医院消化科接受ESD治疗的160例单一食管病变患者。回顾性收集患者一般信息(年龄、性别)、病变特征(部位、大小、大体形态、病理类型、分化程度、浸润深度)、手术经验、环切大小、手术及麻醉时间等医疗信息。根据手术时间分为长期手术组(超过120 min)和短期手术组(小于120 min)。采用单因素和多因素分析分析影响食管ESD手术时间的因素。结果160例患者中,男性120例(75.0%),女性40例(25.0%)。年龄62.65±8.48岁。病灶大小中位数(四分位间距)为1.70 (1.00,2.65)cm。ESD的中位时间为113.54 (81.25,168.75)min。单因素分析显示,年龄bbb65岁、病变类型为Ⅱa+Ⅱc/Ⅱc、病变大小>2 cm、切除>1/2食管周长与ESD手术时间延长相关(P < 0.05)。多因素分析显示:Ⅱa+Ⅱc/Ⅱc型(OR=2.47, 95%CI: 1.01 ~ 6.06, P=0.047)、病变大小>2 cm (OR=3.41, 95%CI: 1.34 ~ 8.64, P=0.010)、> 1/2食管周切除术(OR=4.24, 95%CI:1.62-11.11, P=0.030)是手术时间超过120 min的独立危险因素。结论Ⅱa+Ⅱc/Ⅱc病变类型、病变大小>2 cm、切除面积>1/2食管周长是延长食管ESD手术时间的独立危险因素。关键词:危险因素;早期食管癌;内镜下粘膜下剥离;手术时间
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引用次数: 0
Diagnosis and treatment of pseudoaneurysm complicated with pancreatitis 假性动脉瘤并发胰腺炎的诊断与治疗
Pub Date : 2019-10-20 DOI: 10.3760/CMA.J.ISSN.1007-5232.2019.10.007
Jinlong Hu, N. Ge, Sheng Wang, Jintao Guo, Xiang Liu, Guoxin Wang
Objective To analyze the diagnosis treatment and methods for pancreatic pseudoaneurysms complicated with pancreatitis. Methods The diagnostic methods, treatments and clinical effects of 11 patients with pancreatic pseudoaneurysms complicated with pancreatitis from January 2006 to December 2014 were retrospectively analyzed in Shengjing hospital. Results Two cases of pancreatic pseudoaneurysms were diagnosed by endoscopic ultrasonography(EUS). Eight cases were diagnosed with contrast-enhanced computed tomography. One case was diagnosed by angiography. Ten patients received endovascular embolization, and nine of them were successfully treated. Rebleeding occurred in one patient 28 days after embolization, and was successfully treated by repeated embolization. One patient was successfully treated by surgery. Conclusion Contrast-enhanced computed tomography and angiography are the current main methods to diagnose pancreatic pseudoaneurysms. With the wide use of EUS in the diagnosis of pancreatic disease, EUS becomes an option for diagnosis of pancreatic pseudoaneurysm. Traditionally, pancreatic pseudoaneurysm is treated by surgery. With the advancement of endovascular techniques, endovascular treatment has become the first-line treatment. Further studies with a large sample size are needed to establish the better diagnostic methods and treatments for pancreatic pseudoaneurysm. Key words: Pancreatitis; Aneurysm, false; Gastrointestinal hemorrhage; Endosonography; Embolization, therapeutic
目的探讨胰腺假性动脉瘤并发胰腺炎的诊断、治疗和方法。方法回顾性分析2006年1月至2014年12月盛京医院11例胰腺假性动脉瘤合并胰腺炎的诊断方法、治疗方法及临床疗效。结果对2例胰腺假性动脉瘤进行超声内镜诊断。8例诊断为对比增强计算机断层扫描。1例经血管造影诊断。10例患者行血管内栓塞治疗,其中9例治疗成功。1例患者在栓塞28天后再次出血,经多次栓塞治疗成功。一名患者通过手术成功治疗。结论增强ct和血管造影是目前诊断胰腺假性动脉瘤的主要方法。随着EUS在胰腺疾病诊断中的广泛应用,EUS成为胰腺假性动脉瘤诊断的一种选择。传统上,胰腺假性动脉瘤是通过手术治疗的。随着血管内技术的进步,血管内治疗已成为一线治疗手段。胰腺假性动脉瘤的诊断方法和治疗方法有待进一步的大样本量研究。关键词:胰腺炎;假动脉瘤;胃肠出血;Endosonography;栓塞,治疗
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引用次数: 0
Disinfection efficacy of peracetic acid disinfectant (type III) on gastrointestinal endoscopy III型过氧乙酸消毒剂对胃肠内镜的消毒效果
Pub Date : 2019-10-20 DOI: 10.3760/CMA.J.ISSN.1007-5232.2019.10.006
Gu Jiaoyang, L. Lan, Xin Yu, Ren Jingmin, Wang Li, Zhang Nan, Wu Honglei, Lin Xingfeng, Guo Jian-qiang
Objective To evaluate the disinfection efficacy of peracetic acid disinfectant (type Ⅲ ) on gastrointestinal endoscopy. Methods Endoscopes were disinfected respectively by 2% glutaraldehyde (GA group) and peracetic acid disinfectant (type Ⅲ ) (PAA group) according to the process by the 2016 version of "Regulation for cleaning and disinfection technique of flexible endoscope" , and then samples were collected through biopsy channel at the specified steps. The bacterial count and pathogenic bacteria of these samples were detected. Hepatitis B virus surface antigen (HBsAg), hepatitis C virus (HCV) antibody and Treponemia pallidum antibody (TP-Ab) were detected by chemiluminesent microparticle immunoassay (CMIA) in the PAA group. The PAA group were continuously sampled for 5 days. Results A total of 56 gastroscopes and 16 colonoscopes were disinfected in the GA group, and 46 gastroscopes and 15 colonoscopes were disinfected in the PAA group. Compared with pre-disinfection, the bacterial count was both significantly reduced in the two groups after disinfection (P 0.05; total qualified rate: 98.36% (60/61) VS 94.44% (68/72), P>0.05]. The qualified rate of colonoscopes in the two groups were both 100.00% (15/15, 16/16). After disinfecting by peracetic acid disinfectant (Type Ⅲ), HBsAg, anti-HCV and TP-Ab were negative. There were no significant differences on colonies number at different steps in a 5-day continuous sampling (P>0.05). Conclusion Peracetic acid disinfectant (type Ⅲ) can provide a satisfied disinfectant effect, and be applied in clinic to meet the requests of high-level disinfection for gastrointestinal endoscopy. Key words: Endoscopes, gastrointestinal; Disinfectants; Peracetic acid disinfectant (type Ⅲ)
目的评价过氧乙酸(Ⅲ型)消毒液对胃肠内镜的消毒效果。方法采用2%戊二醛(GA组)和过氧乙酸消毒剂(Ⅲ型)(PAA组)分别按照2016版《柔性内窥镜清洗消毒技术规程》的流程对内窥镜进行消毒,并按规定步骤通过活检通道采集标本。对这些样品进行细菌计数和致病菌检测。采用化学发光微粒免疫分析法(CMIA)检测PAA组患者乙型肝炎病毒表面抗原(HBsAg)、丙型肝炎病毒(HCV)抗体和梅毒螺旋体抗体(TP-Ab)。PAA组连续取样5 d。结果GA组共消毒胃镜56个、结肠镜16个,PAA组共消毒胃镜46个、结肠镜15个。与消毒前比较,消毒后两组细菌数量均显著减少(P < 0.05;总合格率:98.36% (60/61)VS 94.44% (68/72), P < 0.05]。两组结肠镜检查合格率均为100.00%(15/ 15,16 /16)。经过氧乙酸(Ⅲ型)消毒液消毒后,HBsAg、anti-HCV、TP-Ab均为阴性。在连续5 d的采样中,不同步骤的菌落数无显著差异(P < 0.05)。结论过氧乙酸消毒剂(Ⅲ型)能提供满意的消毒效果,可应用于临床,满足胃肠内镜高水平消毒的要求。关键词:内窥镜;胃肠道;消毒剂;过氧乙酸消毒剂(型号:Ⅲ)
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引用次数: 0
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中华消化内镜杂志
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