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A single-center retrospective study of the surgery outcome of Megarectosigmoid (MRS) after anorectal malformation (ARM) repair 肛肠畸形(ARM)修复后大直肠乙状结肠(MRS)手术结果的单中心回顾性研究
IF 0.3 Pub Date : 2026-01-15 DOI: 10.1016/j.yjpso.2026.100266
Zheng Le , Shao Yifeng , Ming Anxiao , Luo Jianfeng , Diao Mei , Li Long

Background

The Megarectosigmoid (MRS) after anorectal malformation (ARM) repair can have a negative impact on the pediatric quality of life. However, current treatments lack consensus due to variable efficacy.

Objective

To evaluate the long-term outcome of laparoscopic-assisted MRS resection (resection of the dilated sigmoid colon and rectum) with anal reconstruction (LAMR-AR) and provide the indications to surgical treatment for MRS.

Methods

A retrospective cohort analyzed 49 pediatric MRS patients, who all had underwent ARM repair before LAMR-AR. Clinical data included imaging and surgical parameters. Patients were stratified by anal morphology: normal anus group (NAG) vs abnormal anus group (AAG) (stenosis/ectopic anus). Functional outcomes were assessed via Rintala scores (R-score) and Krickenbeck criteria for soiling/constipation.

Results

This study enrolled a cohort of 49 pediatric patients (28 males, 21 females) with a median age of 2.75 years (interquartile range [IQR]: 1.42–3 years). Postoperatively, in normal anus group, constipation decreased from 92.9%(26/28 grade3:26) to 7.1%(2/28 grade2:1 grade3:1)(p<0.01), while soiling increased from 3.6%(1/28 grade3:1) to 57.1%(16/28 grade1:9 grade2:7)(p<0.01). As for the abnormal anus group, constipation decreased from 85.7%(18/21 grade3:18) to 23.8%(5/21 grade2:4 grade3:1)(p<0.01) and soiling increased from 4.8%(1/21 grade3:1) to 71.4%(15/21 grade1:2 grade2:9 grade3:4)(p<0.01).Cases in abnormal anus group showed higher complications after ARM repair rates (32.1% vs 14.3%, p = 0.04 abnormal anus group: wound infection/abscess (5), mucosal prolapse (6), recurrent urethral fistula (1), vaginal fistula (1), vestibular fistula (1), wound dehiscence (1) vs normal anus group: cutaneous fistula (1), urethral fistula (1), perianal abscess (1), mucosal prolapse (1)) and worse outcome in lower R-scores(NAG:17(15–19);AAG:14(11–16) p = 0.012).

Conclusion

LAMR-AR is more recommended for patients without anal abnormalities.
背景肛肠畸形(ARM)修复后的大直肠乙状结肠(MRS)会对儿童的生活质量产生负面影响。然而,由于疗效不一,目前的治疗方法缺乏共识。目的评价腹腔镜辅助MRS切除术(扩张乙状结肠和直肠切除术)联合肛门重建术(LAMR-AR)的远期疗效,为MRS手术治疗提供指征。方法回顾性队列分析49例儿童MRS患者,均在LAMR-AR前行ARM修复术。临床资料包括影像学和手术参数。根据肛门形态对患者进行分层:正常肛门组(NAG)和异常肛门组(AAG)(狭窄/异位肛门)。功能结果通过Rintala评分(R-score)和Krickenbeck标准来评估脏污/便秘。结果本研究纳入49例儿科患者(男28例,女21例),中位年龄2.75岁(四分位数间距[IQR]: 1.42-3岁)。术后肛门正常组便秘由92.9%(26/28 grade3:26)降至7.1%(2/28 grade2:1, grade3:1)(p<0.01),大便由3.6%(1/28 grade3:1)上升至57.1%(16/28 grade1:9, grade2:7)(p<0.01)。肛门异常组便秘由85.7%(18/21 grade3:18)下降至23.8%(5/21 grade2:4 grade3:1)(p<0.01),大便由4.8%(1/21 grade3:1)上升至71.4%(15/21 grade1:2 grade2:9 grade3:4)(p<0.01)。异常肛门组ARM修复术后并发症发生率较高(32.1% vs 14.3%, p = 0.04)异常肛门组伤口感染/脓肿(5例)、黏膜脱垂(6例)、复发性尿道瘘(1例)、阴道瘘(1例)、前庭瘘(1例)、伤口开裂(1例)较正常肛门组皮肤瘘(1例)、尿道瘘(1例)、肛周脓肿(1例)、黏膜脱垂(1例),r -评分较低时预后较差(NAG:17(15-19);AAG:14(11-16) p = 0.012)。结论无肛门异常的患者更推荐使用lamr - ar。
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引用次数: 0
Verrucous venous malformations in children: A case for surgical excision 儿童静脉疣状畸形:一例手术切除
IF 0.3 Pub Date : 2026-01-14 DOI: 10.1016/j.yjpso.2026.100265
Halah Hassan , Hannah Triscott , Professor Roy Kimble
<div><h3>Background</h3><div>Verrucous venous malformations (VVMs) are rare congenital vascular anomalies characterized by ectatic venous channels in the dermis and subcutis, with overlying verrucous epidermal changes. Typically presenting in early childhood, they may cause pain, bleeding, infection, and psychosocial distress. Diagnosis and management are often difficult due to clinical and histopathologic overlap with other vascular lesions. Non-surgical therapies have been trialled with limited success, and surgical excision remains the primary treatment. However, the efficacy of surgery, particularly when combined with reconstructive techniques, has not been systematically compared to alternative modalities.</div></div><div><h3>Materials and Methods</h3><div>Twenty-three paediatric patients (aged one month to 17 years) with congenital or early-onset vascular lesions suspected to be VVMs were evaluated at a tertiary vascular anomalies clinic between 2019 and 2025. Clinical presentation, imaging, histopathology, IHC, and NGS results of a 32-gene vascular anomaly panel were reviewed. All patients underwent biopsy or excision. Data were collected retrospectively from operative reports, pathology results, and follow-up documentation.</div></div><div><h3>Results</h3><div>Twenty-three patients (12 male, 11 female; mean age 6.6 years) were included in this series. Lesions were present at birth in all 23 children. Pain and ulceration were the most common symptoms reported, and most lesions demonstrated progressive enlargement. All were solitary and located on the limbs (<em>n</em> = 19) or trunk (<em>n</em> = 4), with a predilection for the lower limb. Imaging suggested low-flow vascular malformation in 14 patients. Twenty children underwent surgical excision. Excision techniques included elliptical excision, rhomboid flap reconstruction, and, in extensive lesions, staged excision with dermal regeneration templates, negative pressure wound therapy (NPWT) and split-thickness skin grafts (STSG). Adjunctive therapies were trialled in seven patients, including laser treatments such as Pulsed Dye Laser (PDL), Fractional Carbon Dioxide Laser (CO₂) and Neodymium-Doped Yttrium Aluminum Garnet Laser (Nd:YAG), microneedling, sclerotherapy, and topical sirolimus. Histopathology confirmed VVM in 19/21 children; immunohistochemistry showed GLUT1 positivity in 18/19 and D2–40 in 8/19. MAP3K3 mutations were identified in 8/20 patients and a KRIT1 variant in one. Postoperative recovery was uncomplicated in most lesions. No major complications or functional impairments were observed, and most patients achieved satisfactory aesthetic and functional outcomes. Quality-of-life assessment using the BBSIP demonstrated consistent functional and psychosocial benefit.</div></div><div><h3>Conclusions</h3><div>VVMs present diagnostic and therapeutic challenges due to their overlap with other vascular anomalies and variable histopathologic and molecular features. Surgical excision
背景:疣状静脉畸形(VVMs)是一种罕见的先天性血管异常,其特征是真皮和皮下静脉通道扩张,并伴有疣状表皮改变。通常在儿童早期出现,可引起疼痛、出血、感染和社会心理困扰。由于临床和组织病理学与其他血管病变重叠,诊断和治疗往往很困难。非手术治疗的试验取得了有限的成功,手术切除仍然是主要治疗方法。然而,手术的疗效,特别是当与重建技术相结合时,尚未与其他方式进行系统的比较。材料与方法2019年至2025年,在某三级血管异常门诊对23例先天性或早发性血管病变疑似vvm的患儿(1个月~ 17岁)进行评估。我们回顾了32个基因血管异常组的临床表现、影像学、组织病理学、免疫组化和NGS结果。所有患者均行活检或切除。回顾性收集手术报告、病理结果和随访资料。结果本组共纳入23例患者,男12例,女11例,平均年龄6.6岁。所有23名儿童出生时均有病变。疼痛和溃疡是最常见的症状,大多数病变表现为进行性扩大。所有病例均为单发,分布于四肢(n = 19)或躯干(n = 4),以下肢为主。影像学提示低流量血管畸形14例。20名儿童接受了手术切除。切除技术包括椭圆切除、菱形皮瓣重建,在广泛病变中,采用真皮再生模板分阶段切除、负压创面治疗(NPWT)和裂厚皮肤移植(STSG)。辅助治疗在7名患者中进行了试验,包括激光治疗,如脉冲染料激光(PDL)、分数二氧化碳激光(CO₂)和掺钕钇铝石榴石激光(Nd:YAG)、微针、硬化疗法和局部西罗莫司。组织病理学证实19/21例儿童VVM;免疫组化18/19 GLUT1阳性,8/19 D2-40阳性。在8/20的患者中发现了MAP3K3突变,在1例患者中发现了KRIT1变异。大多数病变的术后恢复并不复杂。没有观察到重大并发症或功能损伤,大多数患者获得了令人满意的美学和功能结果。使用BBSIP的生活质量评估显示出一致的功能和社会心理益处。结论svvm与其他血管异常重叠,组织病理和分子特征多变,给诊断和治疗带来了挑战。手术切除仍然是治疗的基石,重建策略,如可生物降解的临时基质(BTM)和STSG,帮助封闭广泛或解剖复杂的病变。辅助治疗,包括激光和微针,可以进一步提高术后美容效果。重要的是,BBSIP评估证实手术提供了实质性的功能和社会心理改善。多学科,个性化的方法是必不可少的,以实现持久的症状缓解,减少复发,并优化护理这些罕见的和复杂的病变。
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引用次数: 0
Advances in surgical technique, functional outcomes, and postoperative care for pectus conditions 胸肌疾病的手术技术、功能结局和术后护理进展
IF 0.3 Pub Date : 2026-01-10 DOI: 10.1016/j.yjpso.2026.100261
Madison C. Betcher, Daniel A. DeUgarte, Veronica F. Sullins, Howard C. Jen, Christine E. Dichter, Justin P. Wagner

Objective

To summarize advances in the last decade of care for pectus deformities—primarily pectus excavatum (PE) and pectus carinatum (PC)—with attention to surgical technique, perioperative outcomes, functional and psychosocial effects, and emerging gaps in standardization.

Methods

Review of recent clinical studies, consensus statements, and large cohort analyses addressing indications, operative and non-operative management, outcomes, and postoperative protocols.

Results

Technique refinements to minimally invasive repair (e.g., multi-bar configurations, bridge fixation, shorter bars, and routine thoracoscopy) have reduced bar displacement and major complications while enabling more complete anterior chest wall remodeling. The modified Ravitch procedure remains an option for adults, complex anatomy, or recurrence, with comparable long-term satisfaction. Non-operative therapies—vacuum bell for selected children and orthotic bracing for PC—achieve good results when initiated early and used consistently. Cardiopulmonary diagnostics increasingly demonstrate postoperative improvements in cardiac output, indices of ventricular performance, and exercise capacity, with pulmonary function changes small or inconsistent. The psychosocial burden of disease is substantial, even in mild deformity, and improves after correction. Enhanced Recovery After Surgery pathways and intercostal nerve cryoablation shorten length of stay, lower opioid exposure, and support same-day discharge in selected programs. Despite progress, indications and preauthorization practices vary widely; reliance on “physiologic” criteria and extensive testing contributes to disparities in access.

Conclusions

Contemporary PE/PC care is safer, more effective, and more patient-centered, but remains heterogeneous. Field-wide, consensus-driven guidance that integrates anatomic severity, symptoms, psychosocial distress, and progression would improve equity of access, align payer policy with evidence, and standardize outcomes-oriented care.
目的总结近十年来胸畸形(主要是漏斗胸(PE)和凸胸(PC))的护理进展,包括手术技术、围手术期结局、功能和心理社会影响以及标准化方面的新差距。方法回顾最近的临床研究、共识声明和大型队列分析,涉及适应症、手术和非手术管理、结果和术后方案。结果微创修复技术的改进(如多棒配置、桥固定、短棒和常规胸腔镜)减少了棒移位和主要并发症,同时使前胸壁重塑更完整。改良的Ravitch手术仍然是成人、复杂解剖结构或复发的一种选择,具有相当的长期满意度。非手术治疗-选择儿童的真空钟和pc的矫形支具-在早期开始并持续使用时获得良好的效果。心肺诊断越来越多地显示出术后心输出量、心室功能指标和运动能力的改善,而肺功能的变化很小或不一致。疾病的社会心理负担是巨大的,即使是轻度畸形,并在矫正后得到改善。增强术后恢复途径和肋间神经冷冻消融术缩短了住院时间,减少了阿片类药物暴露,并在选定的项目中支持当日出院。尽管取得了进展,但适应症和预授权做法差异很大;对“生理”标准的依赖和广泛的检测造成了获取机会的差异。结论当代PE/PC护理更安全、更有效、更以患者为中心,但仍存在异质性。将解剖严重程度、症状、社会心理困扰和病情进展整合在一起的全领域共识导向的指导将改善获得服务的公平性,使付款人政策与证据保持一致,并使以结果为导向的护理标准化。
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引用次数: 0
Management of obstructive peristomal complications in pediatric tracheostomy patients. A case series – Surgical decannulation 小儿气管切开术患者阻塞性口周并发症的处理。病例系列-外科脱管术
IF 0.3 Pub Date : 2026-01-02 DOI: 10.1016/j.yjpso.2025.100259
R. Sancho , M. Díaz , L. Solorio , R. Quimbert , N.N. Mata , A.R. Barraza

Background

Tracheal stenosis and suprastomal granuloma with collapse of the anterior tracheal wall are obstructive complications in pediatric tracheostomy patients. The objective of this study is to determine the safety and prognosis of surgical decannulation with simultaneous resection of the obstructive granuloma and tracheoplasty

Methods

A descriptive study between 2015 and 2024, seven children with obstructive complications associated with tracheostomy were included for surgical treatment with resection of suprastomal granuloma, stomoplasty and tracheoplasty simultaneously in surgical decannulation after failure of endoscopic treatment, surgical, endoscopic and prognostic characteristics are analyzed

Results

Seven, with bronchopulmonary dysplasia (n = 4) and prolonged intubation n = 3), all with obstructive suprastomal granulomas > 95% of the airway with failure of endoscopic resection, all with dynamic peristomal obstruction >75% and in 2 of them infrastomal tracheal stenosis Cotton III and IV, 5 were treated with granuloma resection, stomoplasty and anterior tracheoplasty achieving immediate extubation in 4 and one remained intubated for 24 h due to supraglottic edema, and in 2 granuloma resection, anterior malacia and infrastomal stenosis with end-to-end tracheal anastomosis were performed, all with successful decannulation

Conclusions

Surgical decannulation in the treatment of obstructive peristomal complications in children with tracheostomy is a safe option, with low morbidity and no recurrence with zero mortality when endoscopic treatment has failed

Level of evidence

IV
背景:气管狭窄和口上肉芽肿伴气管前壁塌陷是小儿气管切开术患者的梗阻性并发症。本研究旨在探讨阻塞性肉芽肿切除合并气管成形术的安全性及预后。方法在2015 - 2024年间对7例气管造瘘相关梗阻性并发症患儿进行描述性研究,在内镜治疗失败后,同时行口上肉芽肿切除、造口成形术和气管成形术。结果支气管肺发育不良7例(n = 4),气管插管时间延长3例(n = 3),均为梗阻性口上肉芽肿,95%的气道内镜切除失败,全部为动态口周梗阻,75%的气道内镜切除失败,其中2例口下气管狭窄Cotton III和IV, 5例行肉芽肿切除术。4例因声门上水肿立即拔管,1例因声门上水肿插管24 h, 2例肉芽肿切除,行前软化和口下狭窄端到端气管吻合,均成功脱环。结论手术脱环治疗气管切开术患儿阻塞性口周并发症是一种安全的选择。当内镜治疗失败时,发病率低,无复发,零死亡率
{"title":"Management of obstructive peristomal complications in pediatric tracheostomy patients. A case series – Surgical decannulation","authors":"R. Sancho ,&nbsp;M. Díaz ,&nbsp;L. Solorio ,&nbsp;R. Quimbert ,&nbsp;N.N. Mata ,&nbsp;A.R. Barraza","doi":"10.1016/j.yjpso.2025.100259","DOIUrl":"10.1016/j.yjpso.2025.100259","url":null,"abstract":"<div><h3>Background</h3><div>Tracheal stenosis and suprastomal granuloma with collapse of the anterior tracheal wall are obstructive complications in pediatric tracheostomy patients. The objective of this study is to determine the safety and prognosis of surgical decannulation with simultaneous resection of the obstructive granuloma and tracheoplasty</div></div><div><h3>Methods</h3><div>A descriptive study between 2015 and 2024, seven children with obstructive complications associated with tracheostomy were included for surgical treatment with resection of suprastomal granuloma, stomoplasty and tracheoplasty simultaneously in surgical decannulation after failure of endoscopic treatment, surgical, endoscopic and prognostic characteristics are analyzed</div></div><div><h3>Results</h3><div>Seven, with bronchopulmonary dysplasia (n = 4) and prolonged intubation <em>n</em> = 3), all with obstructive suprastomal granulomas &gt; 95% of the airway with failure of endoscopic resection, all with dynamic peristomal obstruction &gt;75% and in 2 of them infrastomal tracheal stenosis Cotton III and IV, 5 were treated with granuloma resection, stomoplasty and anterior tracheoplasty achieving immediate extubation in 4 and one remained intubated for 24 h due to supraglottic edema, and in 2 granuloma resection, anterior malacia and infrastomal stenosis with end-to-end tracheal anastomosis were performed, all with successful decannulation</div></div><div><h3>Conclusions</h3><div>Surgical decannulation in the treatment of obstructive peristomal complications in children with tracheostomy is a safe option, with low morbidity and no recurrence with zero mortality when endoscopic treatment has failed</div></div><div><h3>Level of evidence</h3><div>IV</div></div>","PeriodicalId":100821,"journal":{"name":"Journal of Pediatric Surgery Open","volume":"14 ","pages":"Article 100259"},"PeriodicalIF":0.3,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146080590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial Board Page 编委会页面
IF 0.3 Pub Date : 2026-01-01 DOI: 10.1016/S2949-7116(26)00003-1
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引用次数: 0
Incidence of intestinal volvulus in pediatric patients with intestinal malrotation: A single institution's experience 儿童肠道旋转不良患者肠扭转的发生率:单一机构的经验
IF 0.3 Pub Date : 2026-01-01 DOI: 10.1016/j.yjpso.2025.100260
Takahiro Hosokawa , Hiroshi Kawashima , Tomoko Hara , Yumiko Sato , Yutaka Tanami , Eiji Oguma

Purpose

We investigated the future occurrence of intestinal volvulus in pediatric patients with intestinal malrotation, regardless of whether they are symptomatic or asymptomatic.

Methods

Among 148 pediatric patients with intestinal malrotation, categorization was based on the presence/absence of underlying conditions and the duodenal third portion. Patients with and without the occurrence of intestinal volvulus were compared. We evaluated the cumulative future occurrence of intestinal volvulus from a specified age to 15 years old. The incidence of intestinal malrotation-associated bowel necrosis/surgical complications was recorded.

Results

Seventy-nine of 107 Patients without underlying conditions and without the duodenal third portion, who are typically classified as having the typical type of intestinal malrotation, had intestinal volvulus, and those had significantly higher incidence of intestinal volvulus than that including all patients. The cumulative future occurrence of intestinal volvulus among patients without underlying disease and without duodenal third portion was 73.8 %, and remained at approximately 30 % across other age groups. Among all patients in the present study, including those with and without underlying disease and with typical or atypical malrotation, the incidence was highest at 0–1 years of age (56.1 %) and remained at approximately 20 % across other age groups. Intestinal necrosis/surgical complications occurred in 9.6 %/23.1 % of patients, respectively.

Conclusions

Intestinal volvulus occurs most frequently at 0–1 years of age and remains a risk in the future. These findings, along with considerations of underlying disease, duodenal anatomy, bowel necrosis risk, and surgical complications, provide useful information to assist pediatric surgeons in managing this patient cohort.
目的探讨小儿肠道旋转不良患者在有症状或无症状的情况下肠扭转的发生情况。方法148例小儿肠道旋转不良患者,根据有无基础疾病和十二指肠第三部分进行分类。比较有无肠扭转的患者。我们评估了从特定年龄到15岁肠道扭转的累积未来发生率。记录肠道旋转不良相关肠坏死/手术并发症的发生率。结果107例无基础疾病、无十二指肠第三部分的典型肠旋转不良患者中,79例存在肠扭转,其发生率明显高于全部患者。在没有基础疾病和没有十二指肠第三部分的患者中,肠扭转的累积未来发生率为73.8%,在其他年龄组中保持在约30%。在本研究的所有患者中,包括那些有或没有基础疾病以及典型或非典型旋转不良的患者,发病率在0-1岁时最高(56.1%),在其他年龄组中保持在约20%。肠道坏死/手术并发症发生率分别为9.6% / 23.1%。结论肠扭转多发生于0 ~ 1岁,未来仍有发病风险。这些发现,连同对潜在疾病、十二指肠解剖、肠坏死风险和手术并发症的考虑,为儿科外科医生管理这一患者群体提供了有用的信息。
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引用次数: 0
Development and validation of a perioperative pediatric cardiac risk calculator 围手术期儿科心脏风险计算器的开发和验证
IF 0.3 Pub Date : 2026-01-01 DOI: 10.1016/j.yjpso.2025.100230
Michael L. Daidone , Ryan J. Salvatore , Ryan Z. Gross , Nicholas J. Dante , Darya D. Dehkan , Nicolas L. Carayannopoulos , Sathyaprasad C. Burjonrappa

Background

Numerous tools for cardiac risk stratification exist for the adult population. While each has its strengths, there remains a need for a calculator that reliably predicts the cardiac risk across all types of pediatric surgery. We aim to develop and validate a novel risk stratification tool predicting the probability of 30-day post-operative cardiac arrest in pediatric surgical patients.

Methods

Data from the 2020-2022 NSQIP Pediatric Database were analyzed. Forty nine risk factors were identified from the NSQIP database and used as potential predictors. Multicollinearity was evaluated by calculating the variance inflation factor for each predictor, and a reduced set of 21 variables was selected. Multiple models were created to assess the impact of different preoperative factors on the 30-day cardiac arrest risk using reduced and full variables. Calibration plots comparing the predicted probabilities with the actual outcomes across different probability bins were generated, and the Brier Score, C-Statistic, and H-L Values were calculated and used to compare the models’ performance. Validation was then performed using NSQIP Pediatric Data from 2018-2019, and sensitivity and specificity were calculated. From this data, an interactive application was created.

Results

Of all models developed and tested, the logistic regression model with reduced variables produced the best overall performance with a Brier score, C-statistic, and H-L value of 0.0021, 0.94, and 0.25, respectively. Upon validation, the sensitivity and specificity were 0.90 and 0.82, respectively.

Conclusions

The developed and validated novel risk calculator accurately predicts the risk of post-operative cardiac arrest in pediatric patients.
背景:对于成人人群,有许多心脏风险分层的工具。虽然每种方法都有其优点,但仍然需要一个计算器来可靠地预测所有类型的儿科手术的心脏风险。我们的目标是开发和验证一种新的风险分层工具,预测小儿外科患者术后30天心脏骤停的概率。方法分析2020-2022年NSQIP儿科数据库中的数据。从NSQIP数据库中确定49个危险因素,并将其作为潜在的预测因素。通过计算每个预测因子的方差膨胀因子来评估多重共线性,并选择了一个精简的21个变量集。我们创建了多个模型来评估不同的术前因素对30天心脏骤停风险的影响,使用减少的和完整的变量。生成比较不同概率箱预测概率与实际结果的校准图,并计算Brier Score、C-Statistic和H-L值,用于比较模型的性能。然后使用2018-2019年NSQIP儿科数据进行验证,并计算敏感性和特异性。根据这些数据,创建了一个交互式应用程序。结果在所有开发和测试的模型中,减少变量的logistic回归模型的总体性能最好,Brier评分、c统计量和H-L值分别为0.0021、0.94和0.25。经验证,灵敏度和特异性分别为0.90和0.82。结论开发并验证的新型风险计算器能够准确预测儿科患者术后心脏骤停的风险。
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引用次数: 0
Outcomes of selective case assignment for pediatric appendectomy in a teaching hospital: A seven-year analysis of resident training and surgical approach selection 某教学医院小儿阑尾切除术选择性病例分配的结果:住院医师培训和手术入路选择的7年分析
IF 0.3 Pub Date : 2026-01-01 DOI: 10.1016/j.yjpso.2025.100257
Ming-Yu Hsieh , Tzu-Ling Wang , Pen-Hua Su , Ming-Chih Chou

Background

Appendectomy remains the gold standard treatment for appendicitis in pediatric patients. In teaching hospitals facing workforce constraints, the integration of laparoscopic techniques presents unique challenges in balancing optimal patient outcomes with surgical education. This study evaluates the clinical outcomes of a selective case assignment system that evolved to address these dual objectives in pediatric appendectomy.

Methods

We conducted a retrospective cohort study of 63 consecutive pediatric patients (≤18 years) who underwent appendectomy between January 2013 and December 2019 at a single tertiary teaching hospital. Complicated appendicitis was defined as perforated, gangrenous, or abscess-forming appendicitis based on operative findings and histopathology. Primary outcomes included length of hospital stay and complications. Case assignment patterns, surgeon experience levels, and temporal trends were analyzed to characterize institutional practices.

Results

Of 63 patients, 37 (58.7 %) underwent open appendectomy and 26 (41.3 %) laparoscopic appendectomy. No significant differences were observed in baseline characteristics. Case assignment patterns revealed systematic selection: attending surgeons performed 78.4 % of open procedures, predominantly for complicated cases (89.7 % of attending-performed open cases), while supervised chief residents performed 69.2 % of laparoscopic procedures with selective inclusion of complicated cases (61.1 %). Length of hospital stay was comparable (median 4 vs 3 days, p = 0.245). No major complications occurred in either group. Laparoscopic utilization increased from 20 % (2013) to 60 % (2019), p = 0.021 for trend.

Conclusions

Selective case assignment combined with structured supervision allowed safe integration of laparoscopic appendectomy into pediatric surgical training while maintaining acceptable clinical outcomes. These findings suggest that resident participation in minimally invasive pediatric emergency surgery is feasible when supported by appropriate case selection and oversight.
背景阑尾切除术仍然是儿科阑尾炎患者的金标准治疗方法。在面临劳动力限制的教学医院中,腹腔镜技术的整合在平衡最佳患者结果与外科教育方面提出了独特的挑战。本研究评估了选择性病例分配系统的临床结果,该系统旨在解决儿童阑尾切除术的双重目标。方法对2013年1月至2019年12月在某三级教学医院连续行阑尾切除术的63例儿童患者(≤18岁)进行回顾性队列研究。复杂性阑尾炎定义为穿孔、坏疽或脓肿形成的阑尾炎,基于手术表现和组织病理学。主要结局包括住院时间和并发症。分析了病例分配模式、外科医生经验水平和时间趋势,以表征机构实践。结果63例患者中,37例(58.7%)行开放式阑尾切除术,26例(41.3%)行腹腔镜阑尾切除术。基线特征无显著差异。病例分配模式显示系统选择:主治医生执行78.4%的开放式手术,主要是复杂病例(89.7%),而监督总住院医师执行69.2%的腹腔镜手术,有选择地包括复杂病例(61.1%)。住院时间具有可比性(中位数4天vs 3天,p = 0.245)。两组均无重大并发症发生。腹腔镜使用率从2013年的20%上升到2019年的60%,趋势p = 0.021。结论:有选择的病例分配与有组织的监督相结合,可以将腹腔镜阑尾切除术安全纳入儿科手术培训,同时保持可接受的临床结果。这些发现表明,在适当的病例选择和监督的支持下,住院医生参与微创儿科急诊手术是可行的。
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引用次数: 0
Assessment of hospital, surgeon, and geography-related factors associated with timely surgical care for undescended testes in a universal health care system 评估医院、外科医生和地理相关因素在全民医疗保健系统中对隐睾及时手术护理的影响
IF 0.3 Pub Date : 2025-12-30 DOI: 10.1016/j.yjpso.2025.100258
Hyunwoong Harry Chae , Elaine J Redmond , Alex Zheng , Andrew MacNeily , Kourosh Afshar , Erik Skarsgard , Jason M. Sutherland , Soojin Kim

Introduction

Canada’s healthcare system aims to provide equitable access to care. Guidelines recommend surgery for undescended testes (UDT) before 18 months of age. We evaluated time-appropriate access to surgery for UDT patients in Canada.

Methods

We conducted a secondary analysis of UDT patients who received surgery between 2010–2018. Multivariable logistic models identified factors associated with surgery within 18 months.

Results

Among 19,209 UDT cases, 5186 (27.0%) had surgery within 18 months- 5051/17,947 (28.1%) orchidopexies and 135/1262 (10.7%) orchiectomies. Higher odds of timely orchidopexy were observed at teaching children’s (OR 1.52, CI 1.29–1.79, p < 0.001) and teaching non-children’s hospitals (OR 2.21, CI 1.87–2.61, p < 0.001) versus community hospitals. Hospitals with higher UDT volume (2nd–4th quartiles versus 1st quartile hospitals; >46 cases/year) were more likely to perform surgery within 18 months for both procedures (all OR>1, p < 0.05). Pediatric (OR 1.67, CI 1.53–1.84, p < 0.001) and general surgeons (OR 1.89, CI 1.58–2.26, p < 0.001) were more likely than pediatric urologists to operate within 18 months for orchidopexy, while only pediatric surgeons were more likely for to do so for orchiectomy (OR 1.95, CI 1.00–3.79, p = 0.05). Odds of surgery within 18 months declined over time for orchidopexies (OR 0.99, CI 0.97–1.00, p = 0.039) and orchiectomies (OR 0.88, CI 0.81–0.95, p = 0.001).

Conclusion

Fewer than 30% of UDT surgeries in Canada occurred within 18 months. High-volume and teaching hospitals, and pediatric/general surgeons, were more likely to operate within 18 months. Odds of operation within 18 months declined in recent years. Systemic factors may delay care for UDT patients in Canada.
加拿大的医疗保健系统旨在提供公平的医疗服务。指南建议在18个月前手术治疗隐睾(UDT)。我们评估了加拿大UDT患者的手术时机。方法我们对2010-2018年间接受手术的UDT患者进行了二次分析。多变量logistic模型确定了18个月内与手术相关的因素。结果19209例UDT患者中,5186例(27.0%)在18个月内行手术,其中5051/ 17947例(28.1%)行睾丸切除术,135/1262例(10.7%)行睾丸切除术。与社区医院相比,教学儿童医院(OR = 1.52, CI = 1.29-1.79, p < 0.001)和教学非儿童医院(OR = 2.21, CI = 1.87-2.61, p < 0.001)及时进行兰科切除术的几率更高。UDT量较高的医院(第2 - 4四分位数与第1四分位数医院;46例/年)更有可能在18个月内对两种手术进行手术(所有OR>;1, p < 0.05)。儿科(OR 1.67, CI 1.53-1.84, p < 0.001)和普通外科医生(OR 1.89, CI 1.58-2.26, p < 0.001)比儿科泌尿科医生更有可能在18个月内进行睾丸切除术,而只有儿科外科医生更有可能在18个月内进行睾丸切除术(OR 1.95, CI 1.00-3.79, p = 0.05)。随着时间的推移,睾丸切除术(OR 0.99, CI 0.97-1.00, p = 0.039)和睾丸切除术(OR 0.88, CI 0.81-0.95, p = 0.001)在18个月内手术的几率下降。结论在加拿大,不到30%的UDT手术发生在18个月内。大容量医院和教学医院以及儿科/普通外科医生更有可能在18个月内进行手术。近年来,18个月内手术的几率有所下降。在加拿大,系统因素可能会延迟UDT患者的护理。
{"title":"Assessment of hospital, surgeon, and geography-related factors associated with timely surgical care for undescended testes in a universal health care system","authors":"Hyunwoong Harry Chae ,&nbsp;Elaine J Redmond ,&nbsp;Alex Zheng ,&nbsp;Andrew MacNeily ,&nbsp;Kourosh Afshar ,&nbsp;Erik Skarsgard ,&nbsp;Jason M. Sutherland ,&nbsp;Soojin Kim","doi":"10.1016/j.yjpso.2025.100258","DOIUrl":"10.1016/j.yjpso.2025.100258","url":null,"abstract":"<div><h3>Introduction</h3><div>Canada’s healthcare system aims to provide equitable access to care. Guidelines recommend surgery for undescended testes (UDT) before 18 months of age. We evaluated time-appropriate access to surgery for UDT patients in Canada.</div></div><div><h3>Methods</h3><div>We conducted a secondary analysis of UDT patients who received surgery between 2010–2018. Multivariable logistic models identified factors associated with surgery within 18 months.</div></div><div><h3>Results</h3><div>Among 19,209 UDT cases, 5186 (27.0%) had surgery within 18 months- 5051/17,947 (28.1%) orchidopexies and 135/1262 (10.7%) orchiectomies. Higher odds of timely orchidopexy were observed at teaching children’s (OR 1.52, CI 1.29–1.79, <em>p</em> &lt; 0.001) and teaching non-children’s hospitals (OR 2.21, CI 1.87–2.61, <em>p</em> &lt; 0.001) versus community hospitals. Hospitals with higher UDT volume (2nd–4th quartiles versus 1st quartile hospitals; &gt;46 cases/year) were more likely to perform surgery within 18 months for both procedures (all OR&gt;1, <em>p</em> &lt; 0.05). Pediatric (OR 1.67, CI 1.53–1.84, <em>p</em> &lt; 0.001) and general surgeons (OR 1.89, CI 1.58–2.26, <em>p</em> &lt; 0.001) were more likely than pediatric urologists to operate within 18 months for orchidopexy, while only pediatric surgeons were more likely for to do so for orchiectomy (OR 1.95, CI 1.00–3.79, <em>p</em> = 0.05). Odds of surgery within 18 months declined over time for orchidopexies (OR 0.99, CI 0.97–1.00, <em>p</em> = 0.039) and orchiectomies (OR 0.88, CI 0.81–0.95, <em>p</em> = 0.001).</div></div><div><h3>Conclusion</h3><div>Fewer than 30% of UDT surgeries in Canada occurred within 18 months. High-volume and teaching hospitals, and pediatric/general surgeons, were more likely to operate within 18 months. Odds of operation within 18 months declined in recent years. Systemic factors may delay care for UDT patients in Canada.</div></div>","PeriodicalId":100821,"journal":{"name":"Journal of Pediatric Surgery Open","volume":"14 ","pages":"Article 100258"},"PeriodicalIF":0.3,"publicationDate":"2025-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145986720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Satisfactory treatment of pediatric constipation: It is time for sennosides 小儿便秘的满意治疗:是时候使用番泻皂苷了
IF 0.3 Pub Date : 2025-12-11 DOI: 10.1016/j.yjpso.2025.100256
Celeste Carolina Patiño Gonzalez , Agostina Fontaine , Marcos Federico Leyba

IntroductionA

Constipation is a condition affecting children with an estimated prevalence of 9.5–14 %, without gender differences. Its diagnosis is clinical. In some cases, fecal impaction in the rectum produces encopresis or fecal pseudo-incontinence, generating a negative bio-psycho-social impact. While osmotic laxatives like polyethylene glycol (PEG) are the first line of treatment, there are cases refractory to PEG. Stimulant laxatives, such as sennosides, increase colonic motility. The objective of this study is to describe our experience using sennosides for the treatment of constipation in pediatric patients.

Materials and Methods

A retrospective review was conducted on patients treated with sennosides between August 2023 and July 2024. Inclusion criteria: patients aged 1–14 years with idiopathic constipation (Rome IV) or post-surgical constipation (anorectal malformation, Hirschsprung disease). Patients with true fecal incontinence were excluded. A Bowel Management Program was applied with initial disimpaction using enemas followed by daily sennosides (15 mg). Doses were titrated based on response. Therapeutic success (good response) was defined as daily bowel movements, no soiling, and an abdominal radiograph showing no rectal fecal impaction.

Results

Twenty-four patients were treated (median age 66 months; 58 % male). Diagnoses included idiopathic constipation (63 %), anorectal malformation (25 %), and Hirschsprung disease (13 %). Seventy-one percent had a history of poor response to PEG. Successful disimpaction with enemas was achieved in 100 % of required cases. Sennoside doses ranged from 7.5 mg to 45 mg. Clinical response was satisfactory in 96 % of patients. Radiological control showed a clean rectum in 58 % and minimal stool in 42 %. Adverse events included one case of perianal dermatitis and one case of blistering (moderate), both resolving with conservative management.

Conclusion

Treatment with sennosides is feasible and effective for pediatric patients with constipation refractory to other pharmacological treatments, achieving high therapeutic satisfaction.
便秘是一种影响儿童的疾病,估计患病率为9.5 - 14%,无性别差异。它的诊断是临床的。在某些情况下,直肠内的粪便嵌塞会产生粪尿潴留或假性尿失禁,产生负面的生物-心理-社会影响。虽然像聚乙二醇(PEG)这样的渗透性泻药是一线治疗方法,但也有对PEG难治的病例。刺激性泻药,如泻泻皂苷,增加结肠动力。本研究的目的是描述我们的经验,使用sen皂苷治疗便秘的儿科患者。材料与方法对2023年8月至2024年7月期间接受番泻皂苷治疗的患者进行回顾性分析。纳入标准:1-14岁特发性便秘(Rome IV)或术后便秘(肛肠畸形、巨结肠疾病)患者。排除真正的大便失禁患者。采用肠道管理方案,最初使用灌肠清除阻塞,然后每天使用sen皂苷(15毫克)。剂量根据反应进行滴定。治疗成功(反应良好)定义为每日排便,无脏污,腹部x线片显示无直肠粪便嵌塞。结果24例患者接受治疗,中位年龄66个月,男性占58%。诊断包括特发性便秘(63%)、肛肠畸形(25%)和先天性巨结肠疾病(13%)。71%的患者有PEG不良反应史。灌肠清除阻塞的成功率为100%。番泻皂苷的剂量从7.5毫克到45毫克不等。96%的患者临床反应满意。放射学对照显示58%的患者直肠干净,42%的患者粪便极少。不良事件包括1例肛周皮炎和1例水疱(中度),均通过保守处理解决。结论对其他药物治疗难治性便秘的患儿,采用番泻皂苷治疗是可行、有效的,治疗满意度高。
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引用次数: 0
期刊
Journal of Pediatric Surgery Open
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