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Radial nerve palsy in patients presenting with fentanyl/xylazine wounds of the dorsal forearm: A case series 前臂背侧芬太尼/恶嗪伤口患者的桡神经麻痹:病例系列
Pub Date : 2024-03-01 DOI: 10.1016/j.orthop.2024.01.004
Ashley Sun, Mikayla Borusiewicz, T. Shane Johnson

Introduction

The presence of synthetic compounds like xylazine in the illicit opioid supply of the United States has led to presentations of unique upper extremity wounds in persons who inject drugs. As an alpha-2 adrenergic receptor agonist, xylazine causes local vasoconstriction of blood vessels as well as central nervous system depression. With increased vasoconstriction, patients experience more issues with adequate perfusion which is hypothesized to cause nerve deficiencies near injection sites.

Methods

Three patients presenting with a history of deep upper extremity forearm wounds secondary to injection with xylazine and fentanyl had clinically significant radial nerve palsies. Each patient's presentation and clinical course was observed and reported.

Results

In all three cases, patients presented with chronic necrotic forearm wounds that required repeated surgical debridement and wound care. There was evidence of weakness in the radial nerve distribution, with patients exhibiting dysfunction of the extrinsic digital and wrist extensors.

Conclusion

Providers should be aware of a common manifestation of radial nerve deficiency in upper extremity wounds in patients with a history of fentanyl-xylazine injections. While surgical management of nerve palsies such as tendon transfers are options for treatment, successful long-term treatment must also rely on multidisciplinary care for addiction and psychosocial support for ideal functional outcomes.

导言:美国非法阿片类药物供应中出现的合成化合物(如甲苯噻嗪)导致注射吸毒者出现独特的上肢伤口。作为一种α-2肾上腺素能受体激动剂,异丙嗪会导致局部血管收缩以及中枢神经系统抑制。随着血管收缩的加剧,患者会遇到更多灌注不足的问题,据推测这将导致注射部位附近的神经缺损。结果在所有三个病例中,患者的前臂伤口均呈慢性坏死,需要反复进行手术清创和伤口护理。有证据表明患者的桡神经分布无力,表现为外侧数字肌和腕部伸肌功能障碍。结论对于有芬太尼-恶嗪注射史的患者,医务人员应注意上肢伤口中桡神经缺失的常见表现。虽然手术治疗神经麻痹(如肌腱转移)是治疗方法的一种选择,但成功的长期治疗还必须依靠多学科治疗成瘾和社会心理支持,以获得理想的功能效果。
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引用次数: 0
“Review of contemporary non-surgical management techniques for metacarpal fractures: Anatomy and rehabilitation strategies” "当代掌骨骨折非手术治疗技术综述:解剖与康复策略"
Pub Date : 2024-03-01 DOI: 10.1016/j.orthop.2024.02.001
Paolo Boccolari, Roberto Tedeschi, Daniela Platano, Danilo Donati

This comprehensive study explores the various aspects of metacarpal fractures, a prevalent condition in hand injuries. We delve into the anatomy of the metacarpals, elucidating how their structural characteristics influence fracture mechanics and treatment options. Special attention is given to the diverse types of fractures, particularly the differing tolerances for angular, shortening, and rotational deformities. The manuscript extensively reviews conservative treatment approaches, emphasizing the efficacy of non-surgical methods like modified braces and active mobilization techniques. Additionally, we provide a nuanced understanding of specific fracture types, such as neck fractures, highlighting their unique healing dynamics. This research offers valuable insights for orthopedic and plastic surgery practitioners, advancing the understanding and management of metacarpal fractures.

本综合研究探讨了掌骨骨折的各个方面,掌骨骨折是手部损伤的常见病。我们深入探讨了掌骨的解剖结构,阐明了掌骨的结构特点如何影响骨折力学和治疗方案。我们特别关注骨折的不同类型,尤其是对角度、缩短和旋转畸形的不同容忍度。书稿广泛评述了保守治疗方法,强调了改良支具和主动活动技术等非手术方法的疗效。此外,我们还对颈部骨折等特殊骨折类型进行了细致入微的了解,强调了其独特的愈合动态。这项研究为骨科和整形外科医生提供了宝贵的见解,促进了对掌骨骨折的理解和管理。
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引用次数: 0
Intra- medullary nail fixation as a treatment method for impending fracture non-union of a near-total trans-metacarpal amputation initially treated with K-wire fixation – A case report 髓内钉固定作为一种治疗方法,用于治疗最初采用 K 线固定治疗的近完全经掌截肢的即将发生的骨折不愈合 - 病例报告
Pub Date : 2024-02-08 DOI: 10.1016/j.orthop.2024.01.003
Brendan Podszus BS , Jessica Bigner MD , Manas Nigam MD , Ramon DeJesus MD

In hand and digital replantation, Kirschner wires (K-wires) osteosynthesis is regularly used for bone fixation. Percutaneous K-wire fixation (PKWF) has several disadvantages, such as restriction of range of motion (ROM)—as it often crosses the soft tissues of the joints—, need for early extraction before bone-union prolonging immobilization, potentially increasing pin tract infection, and the fact that it does not offer the strongest type of fixation construct compared to other methods.

All these factors limit early ROM rehabilitation protocols, therefore impacting functional outcomes. We present a case report of a near-total trans metacarpal (MCP) hand crush amputation by a hydraulic press injury that initially underwent PKWF. The K- wires were extracted at seven weeks post-operatively. The concern of impending non-union and the need for prolonged immobilization after K-wire extraction was addressed by intra-medullary nail fixation (IMNF).

In this case, we decided to utilize a less conventional method of osteo-synthesis IMNF to address the concern of impending non-union after initial fixation with K-wires in TMCHR. It provided a stronger fixation construct, no splint immobilization time, and early ROM rehabilitation protocol. All these factors facilitate bone union and improve functional outcomes.

This should stimulate further research for this type of situation between IMNF and other types of osteosynthesis by studying the incidence of non-union, infection rates, functional results, and other outcomes. This could also stimulate fabrication, in the laboratory, of intra-medullary nails for metacarpals with antibiotic impregnated hydroxyapatite/poly-L-lactide (HPLLA)—which are not only bioabsorbable, but also osteoconductive—for osteosynthesis in crushed amputations or comminuted fractures. There are several reports in the literature for digital replantation, but none found for amputations at the MCP level.

在手部和数字再植手术中,Kirschner 钢丝(K-wires)骨合成术通常用于骨固定。经皮K线固定术(PKWF)有几个缺点,如活动范围(ROM)受限--因为它经常穿过关节软组织--、需要在骨愈合前尽早拔出延长固定时间、可能增加针道感染,以及与其他方法相比,它不能提供最坚固的固定结构。我们报告了一例因液压伤导致近乎完全经掌骨(MCP)手掌挤压截肢的病例,患者最初接受了 PKWF。术后七周,K线被拔出。在这个病例中,我们决定采用一种不太传统的骨合成 IMNF 方法,以解决 TMCHR 最初使用 K 线固定后可能出现的不愈合问题。它提供了更坚固的固定结构、无需夹板固定时间和早期 ROM 康复方案。所有这些因素都能促进骨结合并改善功能结果。这应通过研究非骨结合的发生率、感染率、功能结果和其他结果,促进对 IMNF 和其他类型骨合成之间的这种情况的进一步研究。这还能促进在实验室中制造髓内钉,用于掌骨与抗生素浸渍羟基磷灰石/聚左旋乳酸(HPLLA)的髓内钉,这种髓内钉不仅具有生物可吸收性,还具有骨传导性,可用于粉碎性截肢或粉碎性骨折的骨合成。文献中有几篇关于数字再植的报道,但没有一篇是关于 MCP 水平截肢的。
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引用次数: 0
A Retrospective Cohort Study of the Anterolateral Thigh Flap in Lower Extremity Traumatic Reconstruction. Does the Muscle Matter? 大腿前外侧皮瓣在下肢创伤重建中的回顾性队列研究。肌肉是否重要?
Pub Date : 2024-01-21 DOI: 10.1016/j.orthop.2024.01.002
Idean Roohani , Katelyn Kondra , Eloise Stanton , Jacob A. Becerra , Ishani D. Premaratne , David A. Daar , Joseph N. Carey

Background

Anterolateral thigh (ALT) flaps has served as a workhorse in lower extremity reconstruction. Flap design showcases both fasciocutaneous (ALT-FC) and myocutaneous variants; the latter includes variable amounts of vastus lateralis muscle (ALT-VL). This study aims to evaluate outcomes of ALT flaps for lower extremity reconstruction at a Level 1 trauma center between ALT-FC and ALT-VL variants and assess if there is any added benefit of muscle in flap design.

Methods

A retrospective review was conducted at Los Angeles General Medical Center (2007–2022). Demographics, medical comorbidities, injury characteristics, and outcomes were collected. Outcomes included flap necrosis, postoperative infection, and ambulatory function.

Results

Among 413 flaps placed, 63 were ALT flaps, of which 43 (68.3 %) were ALT-FC and 20 (31.7 %) were ALT-VL. Patient comorbidities, defect size, and wound severity were not significantly different across cohorts. Infectious and flap outcomes were comparable between cohorts, yet significantly more patients with hypertension and diabetes mellitus had osteomyelitis overall and in the ALT-FC cohort; patients with diabetes mellitus had significantly more flap complications. Flap survival was 96.8 % with 58.7 % of patients being fully ambulatory, without significance across degrees of ambulation or time to full ambulation.

Conclusions

Our findings demonstrated good outcomes with low rates of infection and flap loss that were comparable between both ALT-FC and ALT-VL cohorts. ALT-FC has recently been favored given decreased donor site morbidity without impaired function or infectious/flap complications. Accordingly, our findings may suggest that the addition of muscle to flap design may not be necessary for successful reconstruction.

背景大腿外侧(ALT)皮瓣一直是下肢重建的主力。皮瓣设计有筋膜皮瓣(ALT-FC)和肌皮瓣两种变体;后者包括不同数量的大腿外侧肌(ALT-VL)。本研究旨在评估一级创伤中心的 ALT 皮瓣在 ALT-FC 和 ALT-VL 两种变体之间用于下肢重建的效果,并评估肌肉在皮瓣设计中是否有任何额外的益处。方法在洛杉矶综合医疗中心进行了一项回顾性研究(2007-2022 年)。收集了人口统计学资料、合并症、损伤特征和结果。结果在放置的413个皮瓣中,63个为ALT皮瓣,其中43个(68.3%)为ALT-FC皮瓣,20个(31.7%)为ALT-VL皮瓣。各组患者的合并症、缺损大小和伤口严重程度无明显差异。各组间的感染和皮瓣结果相当,但高血压和糖尿病患者发生骨髓炎的比例明显高于ALT-FC组;糖尿病患者的皮瓣并发症明显高于ALT-VL组。我们的研究结果表明,ALT-FC 和 ALT-VL 两组患者的感染率和皮瓣脱落率都很低,结果良好。ALT-FC 近来受到青睐,因为它降低了供体部位的发病率,同时不会损害功能或引发感染/皮瓣并发症。因此,我们的研究结果可能表明,在皮瓣设计中增加肌肉可能不是成功重建的必要条件。
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引用次数: 0
Multidisciplinary and orthoplastic approach to diabetic foot reconstruction 糖尿病足重建的多学科整形方法
Pub Date : 2024-01-18 DOI: 10.1016/j.orthop.2024.01.001
Joon Pio Hong

The reconstructive surgeons are an important component in any multidisciplinary approach for the treatment of diabetic foot wounds. When technically feasible, the trend of management has shifted from major amputation to limb salvage. Furthermore, the reconstruction is not only providing adequate coverage but allowing the best possible function with minimum recurrence. By utilizing the orthoplastic approach, we can achieve these goals. The diabetic foot is one of the most difficult fields for reconstruction. With multidisciplinary and orthoplastic approach combined, the reconstructive surgeon can play a crucial part in avoiding amputation and providing an improved quality of life.

在治疗糖尿病足伤口的任何多学科方法中,整形外科医生都是重要的组成部分。在技术可行的情况下,治疗趋势已从大截肢转向肢体挽救。此外,重建不仅要提供足够的覆盖面,还要在尽可能减少复发的情况下实现最佳功能。利用整形方法,我们可以实现这些目标。糖尿病足是最难重建的部位之一。结合多学科和矫形方法,重建外科医生可以在避免截肢和提高生活质量方面发挥重要作用。
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引用次数: 0
Exploration of the vascular angiosome of the extended lateral arm free flap: A cohort study in cadavers 扩展侧臂游离皮瓣血管体的探索:一项尸体队列研究
Pub Date : 2023-11-08 DOI: 10.1016/j.orthop.2023.11.001
Jay P. Narula , Jason D. Wink , Joseph Catapano , Christopher L. Forthman , Valeriy Shubinets

The lateral arm flap is a highly reliable and versatile fasciocutaneous flap for extremity reconstruction. The flap can be harvested in an extended fashion to include the thin skin of the proximal forearm. In the extended version, the maximum amount of skin that can be harvested from the forearm remains unknown. We performed a cohort fresh frozen cadaver dye injection study to investigate this question. A total of seventeen cadaver flap dissections were performed. Our primary goal was to capture the complete angiosome of the extended lateral arm flap, including length and width. Our secondary goal was to explore how much of the flap can be safely harvested distally, past the lateral epicondyle. The overall mean area of dye staining was 23.48±4.60 cm2, which represents the angiosome of the flap. The dye traveled an average of 3.60±4.94 cm into the forearm, past the lateral epicondyle, which suggests a “safe” zone for distal flap harvest. In conclusion, the extended lateral arm flap is a versatile option for extremity reconstruction and can be safely harvested distal to the lateral epicondyle. There is likely a limit, however, to how far distally the skin paddle can extend, which can be explored in future research.

前臂外侧皮瓣是一种高度可靠和多功能的四肢重建筋膜皮瓣。皮瓣可以以延伸的方式收获,包括前臂近端的薄皮肤。在扩展版本中,可以从前臂上收获的最大皮肤量仍然未知。我们进行了一项队列新鲜冷冻尸体染料注射研究来调查这个问题。共进行了17例尸体皮瓣解剖。我们的主要目的是捕获伸展臂外侧皮瓣的完整血管体,包括长度和宽度。我们的第二个目标是探索有多少皮瓣可以安全地切除远端,通过外侧上髁。染色总平均面积23.48±4.60 cm2,代表皮瓣的血管小体。染料进入前臂平均3.60±4.94厘米,经过外侧上髁,这表明远端皮瓣的“安全”区域。总之,前臂外侧皮瓣仍然是四肢重建的一个通用选择,它可以安全地在外侧上髁远端切除。然而,皮肤桨能延伸多远可能是有限制的,这可以在未来的研究中探索。
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引用次数: 0
Experience to date with elective transfemoral amputations incorporating agonist-antagonist myoneural interface (AMI) design 迄今为止选择性经股截肢合并激动-拮抗剂肌神经界面(AMI)设计的经验
Pub Date : 2023-09-21 DOI: 10.1016/j.orthop.2023.09.001
Corey L. Sullivan , Lori Berger , Rachael Chiao , Kendall Clites , Tracy Landry , Tawnee L. Sparling , Matthew J. Carty

Introduction

The agonist-antagonist myoneural interface (AMI) is a surgical construct that, when incorporated into limb amputation, offers to potential to preserve or restore proprioception, augment functionality, reduce neuropathic pain and enhance overall limb stability. We here present our experience to date with AMI construction in the context of transfemoral amputation (TFA).

Methods

Patients were recruited for TFA with AMI construction at Brigham & Women’s and Brigham & Women’s Faulkner Hospital between June 2018 and June 2023. Data collection included demographic information, intraoperative parameters, clinical recovery metrics and complications. All data was then collated and analyzed.

Results

Seven TFA procedures were performed on seven patients during the study period. The operative technique employed evolved significantly over time, and included the development of both native and regenerative AMI models. Four patients were biological males (57%), and mean patient age was 42.0 ± 14.6 years. The etiology of conditions necessitating amputation included traumatic (43%), oncologic (29%), iatrogenic (14%) and congenital (14%). Mean operative time was 566 ± 97 min and average length of stay was 11.7 ± 8.4 days. Average postoperative follow-up was 2.19 ± 1.57 years (range 0.81–4.30 years). Postoperative imaging of AMI constructs demonstrated average muscle excursions of 6±3 mm, and total average limb volume preservation over time was 102 ± 14%. All patients demonstrated a complete wean from narcotic pain medications, with a mean time to wean of 86 ± 79 days. Minimal neuropathic pain was reported after the acute postoperative period. All seven (100%) of the subjects reported functional phantom limb sensation over the same time. Complications included significant soft tissue necrosis in two (29%) patients and minor wound healing issues in one (14%) patient.

Conclusions

TFA incorporating AMI construction appears to offer promising benefits similar to those previously reported in patients undergoing similar interventions at the transtibial level.

激动剂-拮抗剂肌神经界面(AMI)是一种外科手术结构,当用于肢体截肢时,具有保留或恢复本体感觉、增强功能、减少神经性疼痛和增强肢体整体稳定性的潜力。在此,我们介绍了迄今为止在经股截肢(TFA)中AMI构建的经验。患者于2018年6月至2023年6月在布里格姆妇女医院和布里格姆妇女福克纳医院进行AMI构建TFA。数据收集包括人口统计信息、术中参数、临床恢复指标和并发症。然后对所有数据进行整理和分析。在研究期间,对7名患者进行了7次TFA手术。随着时间的推移,所采用的手术技术发生了重大变化,包括原生和再生AMI模型的发展。生物学上男性4例(57%),平均年龄42.0±14.6岁。需要截肢的病因包括创伤(43%)、肿瘤(29%)、医源性(14%)和先天性(14%)。平均手术时间566±97 min,平均住院时间11.7±8.4 d。术后平均随访时间为2.19±1.57年(0.81 ~ 4.30年)。AMI结构的术后成像显示平均肌肉偏移6±3mm,总平均肢体体积随时间的保留为102±14%。所有患者均完全戒断麻醉性止痛药,平均戒断时间为86±79天。术后急性期的神经性疼痛最小。所有7名(100%)受试者在同一时间报告了功能性幻肢感觉。并发症包括2例(29%)患者出现明显的软组织坏死,1例(14%)患者出现轻微伤口愈合问题。合并AMI结构的TFA似乎提供了与先前报道的在胫骨水平进行类似干预的患者相似的有希望的益处。
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引用次数: 0
Peripheral arterial disease and complications of total knee arthroplasty: Indications for advanced vascular imaging and Minimally invasive soft tissue coverage procedures 全膝关节置换术的外周动脉疾病和并发症:先进血管成像和微创软组织覆盖手术的适应症
Pub Date : 2023-09-11 DOI: 10.1016/j.orthop.2023.09.002
Kristopher Katira , Antony Martin , Anna Garbuzov , James Ferrer , Brian Chuong , Ross Parkerson , George Chimento

Soft tissue coverage of knee wounds can be challenging, in particular in the setting of peripheral arterial disease and knee arthroplasty complications. Options for soft-tissue coverage range from conservative wound care to invasive pedicled and free flaps. Unlike traditional wound coverage problems in plastic surgery patients, arthroplasty coverage decisions oblige surgeons to take into account the possibility of secondary orthopedic procedures. The two cases presented in this manuscript demonstrate the importance of vascular imaging, in particular angiography. In both cases, the workhorse medial gastrocnemius flap harvest could have resulted in critical limb ischemia. When secondary orthopedic revision is required at the site of the wound, angiography allows for planning of appropriate soft tissue coverage surgeries.

膝关节伤口的软组织覆盖可能具有挑战性,特别是在周围动脉疾病和膝关节置换术并发症的情况下。软组织覆盖的选择范围从保守的伤口护理到侵入性带蒂皮瓣和自由皮瓣。与传统整形手术患者的伤口覆盖问题不同,关节置换术的覆盖决定迫使外科医生考虑到二次整形手术的可能性。在这个手稿中提出的两个案例证明了血管成像的重要性,特别是血管造影。在这两种情况下,主干腓肠肌内侧皮瓣的切除可能导致严重的肢体缺血。当需要在伤口部位进行二次矫形修复时,血管造影允许计划适当的软组织覆盖手术。
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引用次数: 0
Spino-plastic surgery: A literature review of vascularized bone grafts and their uses in spine reconstruction 脊柱整形外科:血管化骨移植物及其在脊柱重建中的应用的文献综述
Pub Date : 2023-09-09 DOI: 10.1016/j.orthop.2023.09.003
Jonathan L. Jeger , Alec Simoni , Maria Shvedova , Alanna Rebecca , Sebastian Winocour , Maziyar A. Kalani , Michael Bohl , Alexander E. Ropper , Edward M. Reece

The role of plastic surgeons in the world of spine surgery is quickly evolving. The plastic surgeon now serves both a therapeutic and prophylactic role in addressing complications of complex and revision spine surgery. The field of Spino-plastic Surgery is characterized by the use of vascularized bone grafts (VBGs). VBGs are bone segments transferred on their corresponding muscular attachments without the inclusion of a named vessel. The bone graft is adequately vascularized through the connection of the tendon by Sharpey's fibers and their associated microvasculature. VBGs provide an autologous, pedicled tissue rearrangement option with osteoinductive properties and adequate structural support for complex spine reconstruction. VBGs are associated with a lower risk of adverse events and shorter times to fusion than allografts, and bypass the need for lengthy microsurgical anastomosis. Five types of VBGs for spine reconstruction are described in this article, including iliac crest, rib, occiput, scapula, and spinous process VBG. Virtually any vertebral level can be reached for arthrodesis using one or more of these VBGs.

整形外科医生在脊柱外科领域的作用正在迅速发展。整形外科医生现在在解决复杂和翻修脊柱手术的并发症方面既起到治疗作用,也起到预防作用。脊柱整形外科领域的特点是使用血管化骨移植物(VBGs)。vbg是骨段转移到相应的肌肉附着物上,不包含命名血管。骨移植物通过Sharpey's纤维及其相关微血管连接肌腱,使其充分血管化。VBGs为复杂的脊柱重建提供了一种自体的、带蒂的组织重排选择,具有骨诱导特性和足够的结构支持。与同种异体移植物相比,vbg具有较低的不良事件风险和较短的融合时间,并且不需要长时间的显微外科吻合。本文描述了用于脊柱重建的五种VBG类型,包括髂骨、肋骨、枕骨、肩胛骨和棘突VBG。实际上,使用一个或多个VBGs可以达到任何椎体水平进行关节融合术。
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引用次数: 0
Relationship between number of debridements and clinical outcomes in open tibia fractures requiring free flap coverage: A retrospective cohort study 需要游离皮瓣覆盖的开放性胫骨骨折清创次数与临床结果的关系:一项回顾性队列研究
Pub Date : 2023-09-04 DOI: 10.1016/j.orthop.2023.08.002
Hayley Sacks , Jesse Hu , Agraharam Devendra , Shengnan Huang , Jamie Levine , S. Raja Sabapathy , Hari Venkatramani , David Brogan , Martin Boyer , Jacques Hacquebord

Introduction

Open fractures with degloving injuries are commonly managed by serial debridements prior to definitive flap coverage in the United States (US). Some international institutions minimize the number of debridements prior to coverage. The purpose of this study was to compare clinical outcomes in patients with open tibia fractures requiring free flap coverage from institutions with differing debridement philosophies.

Methods

This was a multi-site retrospective cohort study of patients treated at two US tertiary care facilities (serial debridement cohort) and one in India (early total debridement cohort) with Type IIIB or IIIC open tibia fractures requiring free tissue transfer. The number of debridements prior to flap coverage were recorded and primary outcomes were rates of infection, non-union, and flap failure. Fischer's exact tests were used to compare outcomes between the cohorts.

Results

80 patients were included, 44 from India and 36 from the US. Patients in the serial debridement cohort underwent more debridements prior to flap coverage (mean 3.64 vs 1.84, p < 0.001) and had significantly higher rates of infection and non-union compared to patients in the early total debridement cohort (p < 0.05). There were no differences in rates of flap failure between the cohorts.

Conclusions

Patients with open tibia fractures treated at institutions favoring serial debridements underwent more debridements and had higher rates of infection and non-union compared to patients treated at a center favoring early total debridement. Serial debridements may not be necessary prior to flap coverage for open tibia fractures and the current practice should be further investigated.

在美国,开放性骨折脱手套损伤通常在皮瓣覆盖前进行连续清创。一些国际机构在承保前尽量减少清创次数。本研究的目的是比较需要自由皮瓣覆盖的开放性胫骨骨折患者的临床结果,这些患者来自不同清创理念的机构。方法:这是一项多地点回顾性队列研究,研究对象是在美国两个三级医疗机构(连续清创队列)和印度一个(早期全面清创队列)治疗的IIIB或IIIC型开放性胫骨骨折,需要自由组织转移的患者。记录皮瓣覆盖前的清创次数,主要结果是感染、不愈合和皮瓣失败的发生率。Fischer的精确检验用于比较队列之间的结果。结果共纳入80例患者,其中印度44例,美国36例。在连续清创队列中,患者在皮瓣覆盖之前进行了更多的清创(平均3.64 vs 1.84, p <0.001),感染和不愈合的发生率明显高于早期全清创组(p <0.05)。两组间皮瓣失败率无差异。结论:开放性胫骨骨折患者在接受连续清创治疗的机构中比在接受早期全面清创治疗的中心中接受治疗的患者进行了更多的清创,感染和不愈合的发生率更高。对于开放性胫骨骨折,在皮瓣覆盖前可能不需要连续清创,目前的做法应进一步研究。
{"title":"Relationship between number of debridements and clinical outcomes in open tibia fractures requiring free flap coverage: A retrospective cohort study","authors":"Hayley Sacks ,&nbsp;Jesse Hu ,&nbsp;Agraharam Devendra ,&nbsp;Shengnan Huang ,&nbsp;Jamie Levine ,&nbsp;S. Raja Sabapathy ,&nbsp;Hari Venkatramani ,&nbsp;David Brogan ,&nbsp;Martin Boyer ,&nbsp;Jacques Hacquebord","doi":"10.1016/j.orthop.2023.08.002","DOIUrl":"10.1016/j.orthop.2023.08.002","url":null,"abstract":"<div><h3>Introduction</h3><p>Open fractures with degloving injuries are commonly managed by serial debridements prior to definitive flap coverage in the United States (US). Some international institutions minimize the number of debridements prior to coverage. The purpose of this study was to compare clinical outcomes in patients with open tibia fractures requiring free flap coverage from institutions with differing debridement philosophies.</p></div><div><h3>Methods</h3><p>This was a multi-site retrospective cohort study of patients treated at two US tertiary care facilities (serial debridement cohort) and one in India (early total debridement cohort) with Type IIIB or IIIC open tibia fractures requiring free tissue transfer. The number of debridements prior to flap coverage were recorded and primary outcomes were rates of infection, non-union, and flap failure. Fischer's exact tests were used to compare outcomes between the cohorts.</p></div><div><h3>Results</h3><p>80 patients were included, 44 from India and 36 from the US. Patients in the serial debridement cohort underwent more debridements prior to flap coverage (mean 3.64 vs 1.84, p &lt; 0.001) and had significantly higher rates of infection and non-union compared to patients in the early total debridement cohort (p &lt; 0.05). There were no differences in rates of flap failure between the cohorts.</p></div><div><h3>Conclusions</h3><p>Patients with open tibia fractures treated at institutions favoring serial debridements underwent more debridements and had higher rates of infection and non-union compared to patients treated at a center favoring early total debridement. Serial debridements may not be necessary prior to flap coverage for open tibia fractures and the current practice should be further investigated.</p></div>","PeriodicalId":100994,"journal":{"name":"Orthoplastic Surgery","volume":"14 ","pages":"Pages 9-14"},"PeriodicalIF":0.0,"publicationDate":"2023-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666769X23000179/pdfft?md5=1e02e2a3bd8670ca2de8dc175f8a7623&pid=1-s2.0-S2666769X23000179-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80308515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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Orthoplastic Surgery
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