中华核医学与分子影像杂志最新文献

{"title":"Study on tau related disease pattern of Alzheimer′s disease based on 18F-APN-1607 PET imaging","authors":"Jian-Fang Ning, Jiehui Jiang, Chunhua Liu, Wei-qi Bao, Ming Li, Jiaying Lu, Ling Li, C. Zuo, Y. Guan","doi":"10.3760/CMA.J.CN321828-20200205-00034","DOIUrl":"https://doi.org/10.3760/CMA.J.CN321828-20200205-00034","url":null,"abstract":"Objective \u0000Exploring tau related disease pattern (tauRDP) in the brain of Alzheimer′s disease (AD) patients based on 18F-APN-1607 PET scan. \u0000 \u0000 \u0000Methods \u000018F-APN-1607 PET images were collected from 17 AD patients (6 males and 11 females, age: (61.7±12.3) years, Mini-Mental State Examination (MMSE) score: 17.6±7.9) and 10 normal controls (NC; 6 males and 4 females, age: (61.2±4.7) years) from Huashan Hospital of Fudan University. The scaled subprofile model (SSM) based on principal component analysis (PCA) technique was used to construct the tauRDP. Then the expression value of tauRDP in each sample was calculated. The differences on tauRDP expression values between AD patients and NC were compared by independent-sample t test. Pearson correlation analysis was used to analyze the correlation between tauRDP expression values and MMSE values in AD patients. \u0000 \u0000 \u0000Results \u0000The tauRDP area mainly included: precentral gyrus, dorsolateral superior frontal gyrus, middle frontal gyrus, inferior frontal gyrus of opercular part, inferior frontal gyrus of triangular part, supplementary motor area, medial superior frontal gyrus, left median cingulate and paracingulate gyri, right cuneus, superior occipital gyrus, middle occipital gyrus, postcentral gyrus, superior parietal gyrus inferior parietal, but supramarginal and angular gyri, supramarginal gyrus, angular gyrus, precuneus and middle temporal gyrus. There were significant differences (t=4.395, P<0.001) between AD group (12.6±8.0) and NC group (0.0±1.0) in tauRDP expression values. The tauRDP expression values were correlated with MMSE values in AD group significantly (r=-0.566, P=0.018). \u0000 \u0000 \u0000Conclusions \u0000TauRDP established basing on SSM/PCA method can be used to quantitatively express the abnormal spatial distributions of tau deposition. Expression value of tauRDP has the potential to initially assess the severity of AD. \u0000 \u0000 \u0000Key words: \u0000Alzheimer disease; Tau proteins; Benzothiazoles; Positron-emission tomography","PeriodicalId":10099,"journal":{"name":"Chinese Journal of Nuclear Medicine and Molecular Imaging","volume":"40 1","pages":"213-218"},"PeriodicalIF":0.0,"publicationDate":"2020-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46492668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic value of 18F-FDG PET/CT imaging and related factors for patients with classic Hodgkin lymphoma before or after autologous stem cell transplantation","authors":"Wenli Qiao, Jiahua Niu, Wenya Jin, Y. Xing, Tai-song Wang, Jian-hua Song, Jinhua Zhao","doi":"10.3760/CMA.J.CN321828-20190729-00149","DOIUrl":"https://doi.org/10.3760/CMA.J.CN321828-20190729-00149","url":null,"abstract":"Objective \u0000To assess the predictive value of 18F-fluorodeoxyglucose (FDG) PET/CT imaging and relevant factors in the prognosis of patients with classic Hodgkin lymphoma (cHL) before or after autologous stem cell transplantation (ASCT). \u0000 \u0000 \u0000Methods \u0000From January 2008 to June 2017, 55 cHL patients (28 males, 27 females; age: (28.8±9.6) years) confirmed by pathology in Shanghai General Hospital were retrospectively included. 18F-FDG PET/CT imaging was performed before ASCT in 43 cases and after ASCT in 34 cases (22 patients underwent the imaging both before and after ASCT). Patients were divided into positive group (≥4) and negative group (<4) according to 18F-FDG PET/CT imaging results using Deauville 5-point scale. The predictive value of relevant factors in the prognosis was evaluated with progression-free survival (PFS) and overall survival (OS) using Kaplan-Meier survival analysis and log-rank test. Hazard ratio (HR) was calculated by Cox regression model. \u0000 \u0000 \u0000Results \u0000Of 55 cHL patients, 29 (53%) had a progression of disease after a median follow-up of 8 months, and 11 (20%) patients died after a median follow-up of 29.5 months, with the 3-year PFS rate of 46.4% and OS rate of 84.5%. Significant differences of PFS rate were found between patients with or without B symptoms, between patients with or without large mediastinal mass, between patients with international prognostic score (IPS) of 0-2 and those with IPS of 3-7, among patients with different effect of salvage chemotherapy (complete remission (CR), partial remission (PR) + stable disease (SD), progressive disease (PD)), and between patients with negative or positive PET/CT imaging results before or after ASCT (χ2 values: 5.52-20.01, HR: 2.21(95% CI: 1.56-3.12)-5.51(95% CI: 1.86-16.33), all P<0.05). B symptoms and large mediastinal mass were also prognostic factors for OS rate (HR: 5.28(95% CI: 1.14-24.51) and 4.27(95% CI: 1.24-14.79), both P<0.05). The combination of 18F-FDG PET/CT imaging before and after ASCT was statistically significant for predicting PFS (χ2=11.28, P<0.01). Multivariate survival analysis showed that the risk of progression in patients with positive PET/CT results after ASCT was significantly higher than those with negative results (HR=6.20, P<0.01), and the risk of death in patients with B symptoms was significantly higher than those without B symptoms (HR=5.28, P<0.05). \u0000 \u0000 \u0000Conclusion \u000018F-FDG PET/CT imaging results after ASCT have important values for predicting PFS in cHL patients after ASCT, and B symptoms can be used as an important prognostic indicator of OS after ASCT. \u0000 \u0000 \u0000Key words: \u0000Lymphoma; Stem Cells; Transplantation, autologous; Positron-emission tomography; Tomography, X-ray computed; Deoxyglucose","PeriodicalId":10099,"journal":{"name":"Chinese Journal of Nuclear Medicine and Molecular Imaging","volume":"40 1","pages":"147-152"},"PeriodicalIF":0.0,"publicationDate":"2020-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42569600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of guidance template selection on physical dosimetry parameters of 125I seeds implantation for recurrent/metastatic carcinoma of head and neck","authors":"Junma Xu, Feitong Wang, Yuechao Yu, Junjie Wang","doi":"10.3760/CMA.J.CN321828-20190719-00136","DOIUrl":"https://doi.org/10.3760/CMA.J.CN321828-20190719-00136","url":null,"abstract":"","PeriodicalId":10099,"journal":{"name":"中华核医学与分子影像杂志","volume":"40 1","pages":"170-172"},"PeriodicalIF":0.0,"publicationDate":"2020-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48353512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Localization of primary hyperparathyroidism: a case report","authors":"Xuezhu Wang","doi":"10.3760/CMA.J.CN321828-20200225-00068","DOIUrl":"https://doi.org/10.3760/CMA.J.CN321828-20200225-00068","url":null,"abstract":"","PeriodicalId":10099,"journal":{"name":"中华核医学与分子影像杂志","volume":"40 1","pages":"176-178"},"PeriodicalIF":0.0,"publicationDate":"2020-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46227220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research progress of PET metabolic radiomics","authors":"Feihu Xie","doi":"10.3760/CMA.J.CN321828-20190708-00125","DOIUrl":"https://doi.org/10.3760/CMA.J.CN321828-20190708-00125","url":null,"abstract":"In recent years, the development of artificial intelligence technology has promoted the rise of radiomics, which makes image analysis tools, especially texture analysis, extensively concerned in image analysis of PET. In the study of radiomics, tools for image feature analysis such as texture analysis can extract rich information about pathological tissues from the imaging data to describe the characteristics of tumors, judge the prognosis, and evaluate the curative effect of tumors. This review mainly summarizes the research status, progress, challenges and foreground of texture analysis in PET metabolic radiomics. \u0000 \u0000 \u0000Key words: \u0000Radiomics; Metabolism; Positron-emission tomography; Trends","PeriodicalId":10099,"journal":{"name":"Chinese Journal of Nuclear Medicine and Molecular Imaging","volume":"40 1","pages":"183-186"},"PeriodicalIF":0.0,"publicationDate":"2020-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43585678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Room construction and installation of integrated PET/MR","authors":"W. Ruan, Fang Liu, Yongxue Zhang","doi":"10.3760/CMA.J.CN321828-20190926-01328","DOIUrl":"https://doi.org/10.3760/CMA.J.CN321828-20190926-01328","url":null,"abstract":"The integrated PET/MR overcomes the problem of interferences between PET and the strong magnetic field of MRI, realizing the simultaneous acquisition of two modalities, which is a milestone in the field of medical imaging. The use of PET/MR requires the radiopharmaceutical as well as avoids interferences to the homogeneity of main magnetic field and stability of radio-frequency field from surrounding environment. Therefore, the site selection and layout design about integrated PET/MR are more complicated than the single mode system, and the results of installation and debugging should satisfy two imaging modalities (imaging quality and quantitative accuracy). In this paper, the room construction, installation and debugging of integrated PET/MR are discussed, which can supply a reference about key issues in the construction of similar projects. \u0000 \u0000 \u0000Key words: \u0000Facility Design and Construction; Tomography, emission-computed; Magnetic resonance imaging","PeriodicalId":10099,"journal":{"name":"Chinese Journal of Nuclear Medicine and Molecular Imaging","volume":"40 1","pages":"187-190"},"PeriodicalIF":0.0,"publicationDate":"2020-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49605321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictive value of phase analysis of gated myocardial perfusion imaging for major adverse cardiac events in patients with coronary artery disease","authors":"S. Luo, Z. Yao, Congxia Chen, Xu Li, Yue Guo, Zhiguo Yu, Yuyi Zhang","doi":"10.3760/CMA.J.CN321828-20190816-00171","DOIUrl":"https://doi.org/10.3760/CMA.J.CN321828-20190816-00171","url":null,"abstract":"Objective \u0000To evaluate the value of phase analysis of gated myocardial perfusion imaging (GMPI) in predicting major adverse cardiac events (MACE) in patients with coronary atherosclerotic heart disease. \u0000 \u0000 \u0000Methods \u0000Patients who underwent two-day rest-stress GMPI in the Department of Nuclear Medicine of Beijing Hospital from September 2012 to January 2014 were selected as observed subjects and analyzed retrospectively. The general clinical information, GMPI images and related parameters including phase standard deviation (PSD), phase histogram bandwidth (PBW), entropy, left ventricular ejection fraction (LVEF), summed stress score (SSS), peak ejection rate (PER), peak filling rate (PFR) were noted. Patients were followed up until the onset of MACE (cardiac death, nonfatal myocardial infarction, and late revascularization within 60 d after GMPI). χ2 test, independent-sample t test or Wilcoxon rank sum test were used to compare data between different groups. The independent risk factors of MACE were obtained by Cox proportional risk regression model. Kaplan-Meier survival curve analysis was used to analyze the cumulative survival rate without MACE. \u0000 \u0000 \u0000Results \u0000A total of 505 patients (235 males, 270 females, median age: 73 years) were followed up successfully, with a median follow-up period of 55.6(52.0, 60.5) months. There were 54 cases (10.7%) with MACE: 6 patients with cardiac death, 27 patients with non-fatal myocardial infarction, and 21 patients with late revascularization. The incidence of hypertension and hyperlipidemia in patients with MACE was significantly higher than that in patients without MACE (χ2 values: 4.126, 6.021, both P 80°), abnormal entropy(>58 J·mol-1·K-1) and SSS≥12 were independent risk factors for MACE (odds ratio(OR) values: 2.795(95% CI: 1.259-6.201), 3.213(95% CI: 1.468-7.029), 3.640 (95% CI: 1.999-6.628), all P 26.7°), abnormal PBW group and abnormal entropy group were 51.2%, 63.2% and 46.7%, which were significantly lower than those of normal PSD group (92.3%; χ2=77.768, P<0.05), normal PBW group (94.2%; χ2=77.741, P<0.05) and normal entropy group (92.8%; χ2=117.437, P<0.05). The 5-year cumulative MACE-free survival rate (31.7%) of patients with abnormal PBW and SSS≥12 was significantly lower than that of patients with normal PBW or patients with abnormal PBW and SSS<12 (80.1%-94.4%; χ2=185.4, P<0.01). The combination analysis of entropy and SSS showed similar results. \u0000 \u0000 \u0000Conclusions \u0000PBW and entropy obtained by GMPI phase analysis are independent risk factors for predicting MACE in coronary artery disease. GMPI phase analysis is useful for coronary artery disease risk stratification. \u0000 \u0000 \u0000Key words: \u0000Coronary artery disease; Prognosis; Myocardial perfusion imaging; Tomography, emission-computed, single-photon; Tomography, X-ray computed; Technetium Tc 99m sestamibi","PeriodicalId":10099,"journal":{"name":"Chinese Journal of Nuclear Medicine and Molecular Imaging","volume":"40 1","pages":"136-141"},"PeriodicalIF":0.0,"publicationDate":"2020-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44372269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of 13N-NH3, 11C-MET and 18F-FDG PET/CT imaging in the diagnosis and evaluation of cerebral glioma","authors":"Yali Long, Qiao He, Bing Zhang, Xinchong Shi, C. Yi","doi":"10.3760/CMA.J.CN321828-20190724-00141","DOIUrl":"https://doi.org/10.3760/CMA.J.CN321828-20190724-00141","url":null,"abstract":"Objective \u0000To compare the application of 13N-NH3, 11C-methionine (MET) and 18F-fluorodeoxyglucose (FDG) PET/CT imaging in the diagnosis and evaluation of suspected cerebral glioma. \u0000 \u0000 \u0000Methods \u0000From September 2010 to December 2017, ninety patients (54 males, 36 females; age: (40.0±14.0) years) in the First Affiliated Hospital of Sun Yat-sen University with suspected glioma based on clinical diagnosis, who underwent 13N-NH3, 11C-MET and 18F-FDG PET/CT imaging, were prospectively enrolled in the study. All patients were confirmed by histology or clinical and radiological follow-up. Images were interpreted by visual evaluation (higher radioactive uptake in lesions than that in the contralateral normal brain parenchyma was considered as positive (+ ), equal/lower were considered as negative (-)) and semi-quantitative analysis (the maximum standardized uptake value (SUV) of lesion (L) to the mean SUV of normal white matter (WM) (L/WM ratio)). Receiver operating characteristic (ROC) curve analysis was used and the area under curves (AUCs) were calculated and compared. The diagnostic efficacies of 3 imaging methods and the combination for diagnosing gliomas and the abilities to differentiating high-grade gliomas (HGG) and low-grade gliomas (LGG) were compared. \u0000 \u0000 \u0000Results \u0000In 90 patients, 30 HGG, 27 LGG, 10 non-glioma brain tumors and 23 non-neoplastic lesions (NNL) were diagnosed. On visual evaluation, the sensitivities for differentiating tumors from NNL were 62.7%(42/67), 94.0%(63/67) and 35.8% (24/67) for 13N-NH3, 11C-MET and 18F-FDG PET/CT respectively, while the specificities were 95.7%(22/23), 56.5% (13/23) and 65.2% (15/23), and the accuracies were 71.1%(64/90), 84.4%(76/90) and 43.3% (39/90). Taking the metabolic patterns of + /+ /+ , + /+ /- and + /-/- (11C-MET/13N-NH3/18F-FDG) as the diagnosis standard of tumor lesions, the specificity and accuracy of the combined method increased to 73.9%(17/23) and 88.9%(80/90) with the sensitivity remaining the same (94.0%, 63/67). ROC curve analysis (L/WM) showed that the sensitivity, specificity and AUC were 64.2%(43/67), 100%(23/23) and 0.819 for 13N-NH3 PET/CT, and 89.6%(60/67), 69.6%(16/23) and 0.840 for 11C-MET PET/CT (z=-0.316, P>0.05). The accuracy for differentiating high and low grade glioma were 86.0% (49/57), 87.7%(50/57) and 93.0%(53/57) for 13N-NH3, 11C-MET and 18F-FDG PET/CT, with the AUC of 0.896, 0.928 and 0.964, respectively (z values: -0.554 to 1.334, all P>0.05). \u0000 \u0000 \u0000Conclusions \u000013N-NH3 PET/CT imaging has remarkably high specificity but low sensitivity for the differentiation of brain tumors from NNL. 11C-MET PET/CT imaging was found to be highly useful for detection of brain tumors. However, like 18F-FDG, high MET uptake is frequently observed in some NNL. 13N-NH3, 11C-MET and 18F-FDG PET/CT imaging all appear to be valuable for evaluating the histological grade of gliomas, and the combination of them is more useful for the accurate diagnosis of glioma. \u0000 \u0000 \u0000Key words: \u0000Glioma; Pos","PeriodicalId":10099,"journal":{"name":"Chinese Journal of Nuclear Medicine and Molecular Imaging","volume":"40 1","pages":"159-165"},"PeriodicalIF":0.0,"publicationDate":"2020-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44469422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experimental study of 99Tcm-3PRGD2 targeted receptor imaging on angiogenesis in rheumatoid arthritis","authors":"Yun-long Su","doi":"10.3760/CMA.J.CN321828-20190923-00208","DOIUrl":"https://doi.org/10.3760/CMA.J.CN321828-20190923-00208","url":null,"abstract":"Objective \u0000To investigate the feasibility of 99Tcm-hydrazinonicotinamide-(poly-(ethylene glycol))4-E[(poly-(ethylene glycol))4-c((Arg-Gly-Asp)fK)]2 (3PRGD2) in the early diagnosis of rheumatoid arthritis (RA). \u0000 \u0000 \u0000Methods \u0000Sixty female Wistar rats were divided into control group (n=10; injected with saline of 0.3 ml/piece) and collagen-induced arthritis (CIA) group (n=50; injected with type Ⅱ collagen emulsion of 0.3 ml/piece). Rats in 2 groups were subjected to 99Tcm-3PRGD2 planar imaging before modeling, 25 and 45 d after modeling. The changes of the target/non-target ratio (T/NT) of the lesion joint and mediastinum before and after modeling were measured and analyzed in CIA rats, and compared with rats in control group. Pathological examination was conducted. Repeated measures analysis of variance and independent-sample t test were used to analyze the data. \u0000 \u0000 \u0000Results \u0000Thirty-two rats in CIA group were successfully established, and obvious synovitis and synovial thickening, neovascularization were observed in the images. The T/NT of diseased joints in CIA group before modeling, 25 and 45 d after modeling were 0.158±0.023, 0.402±0.144, and 0.705±0.163 (F=286.924, P<0.01). The T/NT of diseased joints at 25 and 45 d after modeling were significantly different from those of control group (0.160±0.028 and 0.158±0.032; t values: -10.484 and -20.917, both P<0.01). Immunohistochemistry results showed positive expressions of vascular endothelial growth factor, αvβ3 and tumor necrosis factor-α in the synovial tissue in of diseased joints in rats of CIA group. \u0000 \u0000 \u0000Conclusion \u000099Tcm-3PRGD2 has high sensitivity for joint synovial neovascularization in rat rheumatoid arthritis models and is expected to be used for early diagnosis of RA. \u0000 \u0000 \u0000Key words: \u0000Arthritis, rheumatoid; Neovascularization, pathologic; Radionuclide imaging; Arginine-glycine-aspartic acid; Rats","PeriodicalId":10099,"journal":{"name":"Chinese Journal of Nuclear Medicine and Molecular Imaging","volume":"40 1","pages":"166-169"},"PeriodicalIF":0.0,"publicationDate":"2020-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43915248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"18F-FDG PET/CT imaging of a case of intravascular large B-cell lymphoma","authors":"Xuetao Chen","doi":"10.3760/CMA.J.CN321828-20190709-00128","DOIUrl":"https://doi.org/10.3760/CMA.J.CN321828-20190709-00128","url":null,"abstract":"","PeriodicalId":10099,"journal":{"name":"Chinese Journal of Nuclear Medicine and Molecular Imaging","volume":"40 1","pages":"173-175"},"PeriodicalIF":0.0,"publicationDate":"2020-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46998706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}