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Dizzy spells and syncope: investigation and management 晕眩和晕厥:调查和处理
Pub Date : 2008-06-01 DOI: 10.1016/j.mpfou.2008.04.004
Neil R. Grubb, Nicholas A. Boon

Dizziness and syncope are common symptoms in the general population, especially the elderly. Syncope can be disabling and result in physical injury and loss of independance. Causes can be divided into arrhythmia, mechanical reduction in cardiac output, inappropriate vasodilatation, neurogenic and metabolic. Patients with cardiac syncope have a poor prognosis unless the cause is quickly identified and treated. The key to making a diagnosis is obtaining a clear history from the patient or a witness of the temporal pattern of symptoms including precipitants, a description of the blackout itself, and speed of recovery. Examination focuses on identification of signs of structural heart disease and postural hypotension. If the history suggests a cardiac diagnosis, echocardiography and ambulatory ECG recording are helpful investigations. For patients with intermittent symptoms suggesting arrhythmia, implantable ECG loop recorders are increasingly used. Tilt testing is used to investigate possible vasovagal syncope, and EEG or MRI head scan can be used to identify potential neurologocal causes of blackouts.

Cardiovascular causes of syncope are treated by removal of reversible triggers (e.g. drugs that cause bradycardia or hypotension) or by treatment of the underlying condition (e.g. permanent pacemaker for symptomatic bradycardia, aortic valve surgery for aortic stenosis). Vasovagal syncope is more difficult to treat but can be helped by avoiding identifiable triggers, use of medication and in some cases dual chamber pacing.

头晕和晕厥是普通人群,尤其是老年人的常见症状。晕厥可致残,导致身体损伤和丧失独立性。其原因可分为心律失常、心输出量机械减少、血管不适当扩张、神经源性和代谢性。心源性晕厥患者预后较差,除非病因得到迅速确认和治疗。诊断的关键是从病人或目击者那里获得关于症状的时间模式的明确病史,包括沉淀物,昏迷本身的描述和恢复速度。检查的重点是鉴别结构性心脏病和体位性低血压的征象。如果病史提示心脏诊断,超声心动图和动态心电图记录是有用的调查。对于间歇性症状提示心律失常的患者,植入式ECG环路记录仪越来越多地被使用。倾斜测试可用于调查可能的血管迷走神经性晕厥,脑电图或MRI头部扫描可用于识别昏厥的潜在神经局部原因。治疗晕厥的心血管原因可通过去除可逆性触发因素(如引起心动过缓或低血压的药物)或治疗基础疾病(如治疗症状性心动过缓的永久性起搏器,治疗主动脉瓣狭窄的主动脉瓣手术)。血管迷走神经性晕厥更难治疗,但可以通过避免可识别的诱因、使用药物和在某些情况下双室起搏来帮助治疗。
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引用次数: 0
Reframing tension and conflict to maximize learning 重新构建紧张和冲突,使学习最大化
Pub Date : 2008-06-01 DOI: 10.1016/j.mpfou.2008.04.005
Katy Newell-Jones, David Colbourne
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引用次数: 0
An F2 general practice release day in the Oxford deanery 牛津大学院长院的F2全科医生释放日
Pub Date : 2008-06-01 DOI: 10.1016/j.mpfou.2008.04.009
Chloe Dallimore
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引用次数: 0
Interface between primary and secondary care 初级和二级保健之间的接口
Pub Date : 2008-06-01 DOI: 10.1016/j.mpfou.2008.04.003
Roger Price, Tim R. Terry
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引用次数: 0
How to read an ECG 如何看心电图
Pub Date : 2008-06-01 DOI: 10.1016/j.mpfou.2008.04.007
Patrick Davey
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引用次数: 0
Alcohol withdrawal syndrome 酒精戒断综合症
Pub Date : 2008-04-01 DOI: 10.1016/j.mpfou.2008.02.010
Allister Vale

Alcohol withdrawal syndrome is a common medical problem and occurs within hours of alcohol cessation or reduction. It is characterized by autonomic hyperactivity, tremor, anxiety, restlessness seizures, hallucinations and delirium. The alcohol withdrawal syndrome may develop in patients admitted to hospital for an unrelated illness (e.g. for an operation) or patients may present in a confused state to the Emergency Department, due to the onset of the syndrome. In both these circumstances, which are medical emergencies, the diagnosis is often delayed as it is not considered. When considered, treatment is often less than optimal. The revised Clinical Institute Withdrawal Assessment for Alcohol (CIWA-Ar) scale should be used to determine both the severity of withdrawal and the need for treatment. If drug treatment is required, patients should be treated with regimens which are patient-specific and flexible to respond to changes in severity of withdrawal (symptom-triggered). Fixed treatment schedules, where the patient is given a standard regimen irrespective of their symptoms, are inappropriate. Long-acting benzodiazepines such as diazepam are the agents to first choice as they have better documented efficacy, a greater margin of safety and a lower abuse potential. Diazepam may be given orally or intravenously, though the oral route is preferred if the patient is able to comply. All patients should receive thiamine 100 mg b.d. orally, unless Wernicke’s encephalopathy or Korsakoff’s psychosis is suspected, when parenteral administration of B vitamins is appropriate.

酒精戒断综合症是一种常见的医学问题,发生在酒精停止或减少的几个小时内。其特点是自主神经亢进、震颤、焦虑、躁动发作、幻觉和谵妄。酒精戒断综合征可能发生在因不相关疾病(如手术)入院的患者身上,也可能发生在因该综合征发作而精神错乱的患者身上。在这两种情况下,都是医疗紧急情况,诊断往往被延误,因为没有考虑到这一点。考虑到这一点,治疗往往不是最理想的。应使用经修订的临床研究所酒精戒断评估(CIWA-Ar)量表来确定戒断的严重程度和治疗的必要性。如果需要药物治疗,患者应采用针对患者的治疗方案,并灵活应对戒断(症状引发)严重程度的变化。不顾病人的症状而给予标准治疗方案的固定治疗方案是不合适的。长效苯二氮卓类药物,如地西泮,是首选药物,因为它们有更好的疗效,更大的安全边际和更低的滥用可能性。地西泮可以口服或静脉注射,但如果患者能够遵守口服途径是首选的。所有患者每天口服100毫克硫胺素,除非怀疑是韦尼克脑病或Korsakoff精神病,当肠外给予B族维生素是合适的。
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引用次数: 2
Should I apply for an academic foundation programme? 我应该申请学术基础课程吗
Pub Date : 2008-04-01 DOI: 10.1016/j.mpfou.2008.03.002
Janet Scott
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引用次数: 1
Managing your portfolio 管理你的投资组合
Pub Date : 2008-04-01 DOI: 10.1016/j.mpfou.2008.02.012
Andrew Long
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引用次数: 0
From medicine to investment banking (and back again) 从医药到投资银行(再回来)
Pub Date : 2008-04-01 DOI: 10.1016/j.mpfou.2008.02.015
Caroline Asprey
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引用次数: 0
How to assess and manage the aggressive patient 如何评估和处理侵略性患者
Pub Date : 2008-04-01 DOI: 10.1016/j.mpfou.2008.02.006
Joseph El-Khoury, Gautam Gulati

The newly qualified doctor is often at the frontline of acute medical services and is therefore likely to be called to situations where a patient is aggressive. This article discusses the systematic assessment of such situations, including an assessment of aetiology and risk assessment. Management issues are outlined with reference to available strategies. Relevent foundation competences are highlighted.

新获得资格的医生经常在急症医疗服务的第一线,因此很可能被叫到病人有攻击性的情况下。本文讨论了此类情况的系统评估,包括病因评估和风险评估。根据现有的战略概述了管理问题。强调相关的基础能力。
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引用次数: 1
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