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Contrast enhanced ultrasound diagnosis of complex cystic renal mass: Interobserver variability based on different Bosniak classification systems 对比增强超声诊断复杂囊性肾肿块:基于不同Bosniak分类系统的观察者间差异
Pub Date : 2023-09-07 DOI: 10.1016/j.wfumbo.2023.100007
Pei Sun , Qing Lu , Luxia Jing , Cuixian Li , Jiexian Wen , Cong Li , Jingjing Wang , Hongli Cao , Beijian Huang

The diagnostic value of Bosniak classification based on contrast enhanced ultrasound (CEUS) on complex cystic renal mass (CRM) was compared among different observers. From 2012 to 2022, 212 complex CRMs, confirmed by pathology or at least 1-year imaging follow-up, were enrolled. The CEUS images of CRM were retrospectively analyzed by two reviewers with different experience in kidney CEUS examination, and each lesion was given the categorizations according the Bosniak ver. 2015 and ver. 2019, respectively. There was good inter-observer agreement (k = 0.689; p < 0.05) for Bosniak ver. 2019. With Bosniak ver. 2019, senior and junior reviewer correctly classified 44 (83.02%), 40 (75.47%) benign lesions as low grade (Ⅰ ∼ ⅡF), and 94 (94.95%), 80 (80.81%) malignant tumors as high grade (Ⅲ or Ⅳ), respectively. Meanwhile, the combination of Bosniak 2019 and senior reviewer demonstrated the highest area under the receiver operating characteristic curve (Az: 0.875, all p < 0.05) than other groups, with the highest specificity (81.10%) and sensitivity (93.90%) among all the groups (95% CI, 0.807–0.943; p < 0.05), respectively. Overall, the senior reviewer combined with Bosniak ver. 2019 was the best choice for the diagnosis of complex CRM.

比较不同观察者之间基于对比增强超声(CEUS)的Bosniak分类对复杂囊性肾肿块(CRM)的诊断价值。从2012年到2022年,共有212例经病理学或至少一年的影像学随访证实的复杂CRM入选。两位具有不同肾脏CEUS检查经验的评审员对CRM的CEUS图像进行了回顾性分析,并分别根据Bosniak 2015年版和2019年版对每个病变进行了分类。2019年波什尼亚克的观察者之间存在良好的一致性(k=0.689;p<;0.05)。Bosniak ver.2019,高级和初级评审员分别正确地将44个(83.02%)、40个(75.47%)良性病变分为低级别(Ⅰ~ⅡF),94个(94.95%)、80个(80.81%)恶性肿瘤分为高级别(Ⅲ或Ⅳ)。同时,与其他组相比,Bosniak 2019和高级评审员的组合在受试者操作特征曲线下的面积最高(Az:0.875,均p<;0.05),在所有组中具有最高的特异性(81.10%)和敏感性(93.90%)(95%CI,0.807–0.943;p<;05)。总体而言,高级评审员结合Bosniak ver.2019是诊断复杂CRM的最佳选择。
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引用次数: 0
Feasibility of teleoperated robotic echocardiography – A pilot study 遥控机器人超声心动图的可行性-一项初步研究
Pub Date : 2023-09-04 DOI: 10.1016/j.wfumbo.2023.100018
H. Solvin , S. Sajadi , M. Lippert , R. Massey , H. Holmstrøm , O. Elle , K. Mathiassen , H. Brun

Purpose

Echocardiography is dependent on highly specialized healthcare professionals. Teleoperated examinations could provide higher availability of specialized care for patients living in rural areas. The objective of this study was to evaluate the feasibility of a teleoperated robotic echocardiography system.

Methods

Twenty-three healthy volunteers underwent teleoperated echocardiography, compared to standard bedside echocardiography. Examination time, image quality, ability to assess cardiac structures, measurements of left ventricular fractional shortening and blood flow velocities were compared. Image quality was rated on a scale from 0 to 3.

Results

Approximately 90% of robotically acquired images were rated as medium quality or better and approximately 80% of cardiac structures were evaluated as assessable by at least one evaluator. Mean image quality was lower for robotic (1.6 ± 0.3) compared to standard clinical examinations (2.5 ± 0.4) (p = 0.001). Left ventricular fractional shortening from the robotic examinations was 2.2%, p = 0.160 (absolute value) lower compared to the reference and showed a variation coefficient of 19%. The calculated Doppler insonation angles deviated from the reference by more than 25° for three of four blood flow velocity measurements. The teleoperated examinations had a mean examination time of 26.4 min and were 1.9 times longer compared to the reference (p = 0.001).

Conclusion

This feasibility study of teleoperated echocardiography shows promising results for the presented system. Clinically satisfactory imaging, particularly measurements of dimension and velocities, requires further development of the system.

目的超声心动图依赖于高度专业化的医疗保健专业人员。远程手术检查可以为生活在农村地区的患者提供更高的专业护理。本研究的目的是评估远程操作机器人超声心动图系统的可行性。方法对23名健康志愿者进行远程操作超声心动图检查,并与标准床边超声心动图进行比较。比较检查时间、图像质量、评估心脏结构的能力、左心室缩短分数和血流速度的测量结果。图像质量从0到3进行评分。结果大约90%的自动采集图像被评为中等质量或更好,大约80%的心脏结构被至少一名评估者评估为可评估。与标准临床检查(2.5±0.4)相比,机器人检查的平均图像质量较低(1.6±0.3)(p=0.001)。机器人检查的左心室缩短率为2.2%,与参考相比,p=0.160(绝对值)较低,变异系数为19%。对于四次血流速度测量中的三次,计算出的多普勒入射角与参考值的偏差超过25°。远程操作检查的平均检查时间为26.4分钟,比参考值长1.9倍(p=0.001)。结论远程操作超声心动图的可行性研究表明,该系统具有良好的效果。临床上令人满意的成像,特别是尺寸和速度的测量,需要进一步开发该系统。
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引用次数: 0
Effectiveness of color Doppler ultrasound and shear-wave elastography for characterization of intestinal inflammation and fibrosis in Crohn's disease: A comparison with surgical histopathology analysis 彩色多普勒超声和剪切波弹性成像对克罗恩病肠道炎症和纤维化特征的有效性:与手术组织病理学分析的比较
Pub Date : 2023-08-25 DOI: 10.1016/j.wfumbo.2023.100017
Tomás Ripollés , María Jesús Martínez-Pérez , José María Paredes , Alfonso Maldonado , Encarna Martí , Gregorio Martin , Lidia Navarro , Andrés Painel

Background & aims

Differentiation between predominantly inflammatory or fibrous strictures is particularly important to decide the optimal therapy in patients with refractory symptoms in Crohn's disease. The purpose of this research was to evaluate the accuracy of color Doppler US and Shear Wave Elastography in differentiating the degree of inflammation or fibrosis in ileal strictures in patients with Crohn's disease by comparing with resected bowel samples.

Materials and methods

Preoperative ultrasound examination, including SWE, was performed in 30 consecutive patients with Crohn's disease undergoing elective bowel resection. Ultrasound variables, Shear Wave Elastography quantitative analysis and visual elastographic color map, were prospectively evaluated. Histopathology grading of acute inflammation using the acute inflammatory score and the degree of fibrostenosis was performed.

Results

In pathology analysis there were 21 segments with severe fibrosis. The mean Shear Wave Elastography value of the stenotic bowel wall was significantly higher in severe fibrosis (3.56 ± 1.4 m/s) than in mild fibrosis (1.89 ± 0.75 m/s) (P = 0.004). Using 2.5 m/s as the cut-off value to discriminate between mild and severe fibrosis, the sensitivity and specificity was 76.2% and 100% with an area under the curve (AUC) of 0.889. The sensitivity and specificity of the visual assessment of the elastographic color map in differentiating severe from mild fibrosis was 82.4% and 88.9%.

Conclusions

this study suggests that Shear Wave Elastography is accurate for detecting severe intestinal fibrosis in Crohn's disease patients. This information may be useful in the treatment strategy for CD.

背景&;目的区分主要是炎症性狭窄还是纤维性狭窄对于决定克罗恩病难治性症状患者的最佳治疗尤为重要。本研究的目的是通过与切除的肠道样本进行比较,评估彩色多普勒超声和剪切波弹性成像在区分克罗恩病患者回肠狭窄炎症或纤维化程度方面的准确性。材料和方法对连续30例接受选择性肠切除术的克罗恩病患者进行了包括SWE在内的再次手术超声检查。前瞻性评价超声变量,剪切波弹性成像定量分析和视觉弹性成像彩色图。使用急性炎症评分和纤维狭窄程度对急性炎症进行组织病理学分级。结果病理分析中有21个节段出现严重纤维化。狭窄肠壁的平均剪切波弹性成像值在严重纤维化(3.56±1.4 m/s)中显著高于轻度纤维化(1.89±0.75 m/s)(P=0.004)。以2.5 m/s作为区分轻度和重度纤维化的截止值,其敏感性和特异性分别为76.2%和100%,曲线下面积(AUC)为0.889。弹性成像彩色图视觉评估在区分重度和轻度纤维化方面的敏感性和特异性分别为82.4%和88.9%。结论本研究表明,剪切波弹性成像对克罗恩病患者的严重肠纤维化检测是准确的。这些信息可能对CD的治疗策略有用。
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引用次数: 0
Pitfalls in sonographic evaluation of placenta accreta spectrum 增胎性胎盘声像图评价的缺陷
Pub Date : 2023-07-24 DOI: 10.1016/j.wfumbo.2023.100016
Anne Kennedy , April Griffith , Brett Einerson , Paula J. Woodward

Placenta accreta spectrum (PAS) is a serious complication of pregnancy. Preoperative diagnosis improves outcome for both mother and infant therefore it is critical that obstetric imagers are aware of the signs of the disease and know how to avoid pitfalls in diagnosis. This article reviews and illustrates the sonographic signs that are most helpful in detection of PAS and provides tips on avoiding pitfalls in diagnosis.

植入性胎盘频谱(PAS)是妊娠期的一种严重并发症。术前诊断可以改善母亲和婴儿的预后,因此产科成像仪必须意识到疾病的迹象,并知道如何避免诊断中的陷阱。本文回顾并说明了对PAS检测最有帮助的超声征象,并提供了避免诊断中陷阱的提示。
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引用次数: 0
Echoes in space: Online training and AI's potential in advancing ultrasound competency 太空回响:在线培训和人工智能在提高超声能力方面的潜力
Pub Date : 2023-07-10 DOI: 10.1016/j.wfumbo.2023.100015
Rebeca Tenajas, David Miraut
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引用次数: 0
Rethinking ultrasound probe maintenance in the era of AI 人工智能时代超声探头维护的再思考
Pub Date : 2023-07-10 DOI: 10.1016/j.wfumbo.2023.100014
Rebeca Tenajas, David Miraut
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引用次数: 0
Predicting female breast cancer by artificial intelligence: Combining clinical information and BI-RADS ultrasound descriptors 人工智能预测女性乳腺癌:结合临床信息和BI-RADS超声描述符
Pub Date : 2023-06-30 DOI: 10.1016/j.wfumbo.2023.100013
Wen-Jia Shen , Hai-Xia Zhou , Ye He , Wei Xing

This study aimed to use Artificial Intelligence (AI) Deep Learning (DL) techniques to predict female breast cancer detected by ultrasound based on clinical data and Breast Imaging Reporting and Data System (BI-RADS) Ultrasound (US) descriptors. We retrospectively gathered data on clinical information and BI-RADS US descriptors of breast lesions from 1051 female patients, forming a comprehensive dataset. Two datasets (A and B) were derived by selecting different variables. A BI-RADS DL-based Network (BD-Net) was developed and trained on Dataset A and B, and its performance was evaluated on an external test set. Radiologists also classified Dataset B and the external test set using BI-RADS US. Performance in predicting the probability of malignancy was evaluated by calculating the Area Under Curve (AUC), accuracy, sensitivity, and specificity. BD-Net achieved an accuracy of 92.5% (95%CI, 90.5–94.2) in predicting breast cancer with a sensitivity of 93.0% (95%CI, 90.3–95.4), a specificity of 92.1% (95%CI, 89.7–94.6), and an AUC of 0.97 (95%CI, 0.96–0.98) on the training data set of dataset A. On the external dataset, the BD-Net showed a sensitivity of 93.8% (95%CI, 87.5–98.8), a specificity of 91.0% (95%CI, 85.0–96.0), and an AUC of 0.92 (95%CI, 0.88–0.97) for predicting breast cancer. The radiologists predicted breast cancer on Dataset B and the external test set with AUC values between 0.75 (95%CI, 0.75–0.79) and 0.82 (95%CI, 0.77–0.87). These results indicate that the BD-Net is effective for predicting ultrasound-detected female breast cancer.

本研究旨在利用人工智能(AI)深度学习(DL)技术,根据临床数据和乳腺成像报告和数据系统(BI-RADS)超声(US)描述符,预测超声检测到的女性乳腺癌症。我们回顾性收集了1051名女性患者的乳腺病变临床信息和BI-RADS US描述符的数据,形成了一个全面的数据集。通过选择不同的变量得出两个数据集(A和B)。在数据集A和B上开发和训练了一个基于BI-RADS DL的网络(BD-Net),并在外部测试集上对其性能进行了评估。放射科医生还使用BI-RADS US对数据集B和外部测试集进行了分类。通过计算曲线下面积(AUC)、准确性、敏感性和特异性来评估预测恶性肿瘤概率的性能。BD-Net预测癌症的准确率为92.5%(95%CI,90.5–94.2),数据集a的训练数据集的敏感性为93.0%(95%CI、90.3–95.4),特异性为92.1%(95%CI和89.7–94.6),AUC为0.97(95%CI与0.96–0.98),预测乳腺癌症的AUC为0.92(95%CI,0.88-0.97)。放射科医生在数据集B和外部测试集上预测了癌症,AUC值介于0.75(95%CI,0.75–0.79)和0.82(95%CI(0.77–0.87)之间。这些结果表明BD-Net对预测超声检测的女性癌症乳腺癌是有效的。
{"title":"Predicting female breast cancer by artificial intelligence: Combining clinical information and BI-RADS ultrasound descriptors","authors":"Wen-Jia Shen ,&nbsp;Hai-Xia Zhou ,&nbsp;Ye He ,&nbsp;Wei Xing","doi":"10.1016/j.wfumbo.2023.100013","DOIUrl":"https://doi.org/10.1016/j.wfumbo.2023.100013","url":null,"abstract":"<div><p>This study aimed to use Artificial Intelligence (AI) Deep Learning (DL) techniques to predict female breast cancer detected by ultrasound based on clinical data and Breast Imaging Reporting and Data System (BI-RADS) Ultrasound (US) descriptors. We retrospectively gathered data on clinical information and BI-RADS US descriptors of breast lesions from 1051 female patients, forming a comprehensive dataset. Two datasets (A and B) were derived by selecting different variables. A BI-RADS DL-based Network (BD-Net) was developed and trained on Dataset A and B, and its performance was evaluated on an external test set. Radiologists also classified Dataset B and the external test set using BI-RADS US. Performance in predicting the probability of malignancy was evaluated by calculating the Area Under Curve (AUC), accuracy, sensitivity, and specificity. BD-Net achieved an accuracy of 92.5% (95%CI, 90.5–94.2) in predicting breast cancer with a sensitivity of 93.0% (95%CI, 90.3–95.4), a specificity of 92.1% (95%CI, 89.7–94.6), and an AUC of 0.97 (95%CI, 0.96–0.98) on the training data set of dataset A. On the external dataset, the BD-Net showed a sensitivity of 93.8% (95%CI, 87.5–98.8), a specificity of 91.0% (95%CI, 85.0–96.0), and an AUC of 0.92 (95%CI, 0.88–0.97) for predicting breast cancer. The radiologists predicted breast cancer on Dataset B and the external test set with AUC values between 0.75 (95%CI, 0.75–0.79) and 0.82 (95%CI, 0.77–0.87). These results indicate that the BD-Net is effective for predicting ultrasound-detected female breast cancer.</p></div>","PeriodicalId":101281,"journal":{"name":"WFUMB Ultrasound Open","volume":"1 2","pages":"Article 100013"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49733899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Differences in ultrasound elevational beam width (slice thickness) between popular handheld devices 流行的手持设备之间超声抬高波束宽度(切片厚度)的差异
Pub Date : 2023-06-28 DOI: 10.1016/j.wfumbo.2023.100009
Harm J. Scholten , Gert Weijers , Marco de Wild , Hendrikus H.M. Korsten , Chris L. de Korte , R. Arthur Bouwman

Background

Handheld ultrasound devices are increasingly used by medical professionals for bedside ultrasound-guided interventions. Especially for vascular access procedures, the width of the imaging plane, known as the slice thickness or elevational beam width is a prominent source for misinterpretation. A wide slice thickness can lead to the interpretation that 2 objects (i.e. needle and vessel) are on the same plane while in fact they are not and thereby negatively influencing the performance of in-plane ultrasound-guided interventions. Therefore, the beam profiles of three popular handheld US devices are tested and compared to a conventional US device.

Methods

The GE VScan, Philips Lumify and Butterfly IQ ​+ ​are tested using a slice phantom to determine the slice thickness. For comparison, a Philips Affiniti machine was investigated. Both linear and curved array settings were analyzed. In a slice phantom, a diffuse scattering plane at an angle of exactly 45° is scanned. For each imaging depth, the vertical height of the imaged rectangle corresponds to the slice thickness at that depth.

Main results

For the linear array transducers, the focus depth ranges from 1.5 to 3.5 cm. At the focus depth, all transducers have a reasonable slice thickness of approximately 1 mm. More superficially, the slice thickness varies between 1 and 4 mm. The curved array probes have larger focus depths, ranging from 2.7 to 7.3 cm. The slice thickness at focus depth varies between 1.4 and 3.8 mm, but at 2 cm depth is even more than 5 mm.

Conclusions

The slice thickness of handheld ultrasound transducers varies between the different devices, and can be suboptimal for superficial in-plane ultrasound-guided interventions. The larger slice thickness of the curved array settings may complicate in-plane guidance. Handheld ultrasound users should be aware of the beam characteristics of their devices to optimize guidance for interventions.

背景医疗专业人员越来越多地使用手持超声设备进行床边超声引导干预。特别是对于血管通路程序,成像平面的宽度,即切片厚度或仰角波束宽度,是误解的主要来源。较宽的切片厚度可能导致2个物体(即针头和血管)在同一平面上,而事实上它们不在同一个平面上,从而对平面内超声引导干预的性能产生负面影响。因此,测试了三种流行的手持US设备的波束轮廓,并将其与传统US设备进行了比较。方法GE VScan、Philips Lumify和Butterfly IQ​+​使用切片体模进行测试以确定切片厚度。为了进行比较,对Philips Affiniti机器进行了研究。分析了线性和弯曲阵列设置。在切片体模中,扫描角度正好为45°的漫散射平面。对于每个成像深度,成像矩形的垂直高度对应于该深度处的切片厚度。主要结果对于线性阵列换能器,聚焦深度范围为1.5至3.5厘米。在聚焦深度下,所有换能器的合理切片厚度约为1毫米。从表面上看,切片厚度在1到4mm之间变化。弯曲阵列探头具有更大的聚焦深度,范围从2.7到7.3厘米。聚焦深度处的切片厚度在1.4到3.8毫米之间变化,但在2厘米深度处甚至超过5毫米。结论手持超声换能器的切片厚度因不同设备而异,对于浅表面内超声引导干预来说可能是次优的。弯曲阵列设置的较大切片厚度可能使平面内引导复杂化。手持超声波用户应了解其设备的波束特性,以优化干预指导。
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引用次数: 0
A preliminary study on the application of sono-elastography in differentiating endometrial carcinoma from benign endometrial lesions in a tertiary government hospital in the Philippines 超声弹性成像在菲律宾三级政府医院鉴别子宫内膜癌与良性病变的初步研究
Pub Date : 2023-06-28 DOI: 10.1016/j.wfumbo.2023.100012
Catherine M. Santos, Nelinda Catherine P. Pangilinan, Maria Cristina C. Franada

[Objective]

To evaluate the diagnostic value of sonoelastography to distinguish endometrial cancer from benign endometrial lesions.

[Methods]

A cross-sectional study was conducted and included 31 subjects with abnormal uterine bleeding who required endometrial sampling. Sonoelastography assessment was done qualitatively and quantitatively using Tsukuba elasticity score and strain ratio, respectively. Results were compared between those with endometrial cancer and those with benign endometrial lesions (hyperplasia and polyp) using Kruskal-Wallis test and Mann-Whitney U test. Diagnostic accuracies of Tsukuba elasticity score and strain ratio in differentiating endometrial cancer from benign endometrial lesions were determined with cut-off values derived from ROC analysis.

[Discussion]

Both the Tsukuba elasticity score and strain ratio value were significantly higher among patients with endometrial cancer (n = 15; mean age: 55.07 ± 8.53 years) compared to those with benign endometrial lesions (n = 16; mean age: 41.63 ± 8.02 years) (P < 0.0001). A Tsukuba elasticity score of ≥3 showed the highest diagnostic accuracy at 93.5%(95%CI: 79.3%–98.2%), with sensitivity of 86.7%(95%CI: 62.1%–96.3%), specificity of 100%(95%CI: 80.6%–100%), PPV of 100%(95%CI: 77.2%–100%), NPV of 88.9%(95%CI: 67.2%–96.9%), positive LR of undefined indicating high value and negative LR of 0.10(95%CI: 0.05–0.40). A Strain ratio value of ≥2 showed the highest diagnostic accuracy at 93.5%(95%CI: 79.3%–98.2%), with sensitivity of 93.3%(95%CI: 70.2%–98.8%), specificity of 93.8%(95%CI: 71.7%–98.9%), PPV of 93.3% (95%CI: 70.2%–98.8%), NPV of 93.8%(95%CI: 71.7%–98.9%), positive LR 14.9(95%CI: 2.1–107.1), and negative LR of 0.07(95%CI: 0.01–0.51).

[Conclusion]

The results indicate that sonoelastography can distinguish endometrial cancer from benign endometrial lesions.

[目的]评价声弹性成像对子宫内膜癌症与良性病变的鉴别诊断价值。[方法]对31例需要子宫内膜取样的异常子宫出血患者进行横断面研究。声弹性成像分别使用筑波弹性评分和应变率进行定性和定量评估。用Kruskal-Wallis检验和Mann--Whitney U检验对癌症子宫内膜和良性子宫内膜病变(增生和息肉)的结果进行比较。根据ROC分析得出的临界值,确定筑波弹性评分和应变率在区分子宫内膜癌症和良性子宫内膜病变中的诊断准确性。[讨论]子宫内膜癌症患者(n=15;平均年龄:55.07±8.53岁)的筑波弹性评分和应变比值均显著高于子宫内膜良性病变患者(n=16;平均年龄41.63±8.02岁)(P<;0.0001),敏感性为86.7%(95%CI:62.1%–96.3%),特异性为100%(95%CI:80.6%-100%),PPV为100%(95%CI:77.2%–100%),NPV为88.9%(95%CID:67.2%–96.9%),未定义的阳性LR表示高值,阴性LR为0.10(95%CI:0.05–0.40)。≥2的菌株比值显示出最高的诊断准确率,为93.5%(95%CI:79.3%-98.2%),灵敏度93.3%(95%CI:70.2%-98.8%),特异性93.8%(95%CI:11.7%-98.9%),PPV 93.3%(95%CI:70.2%-98.8%),NPV 93.8%(95%CID:71.7%-98.9%),阳性LR 14.9(95%CI:2.1-107.1),阴性LR 0.07(95%CI:0.01-0.51)。
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引用次数: 0
Preserving sound arguments and academic dialogue by promoting free-of-charge opinion pieces and letters in WFUMB Ultrasound Open Journal 通过在世界妇联超声公开杂志上推广免费的观点文章和信件,保持合理的论点和学术对话
Pub Date : 2023-06-28 DOI: 10.1016/j.wfumbo.2023.100011
Rebeca Tenajas , David Miraut
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引用次数: 0
期刊
WFUMB Ultrasound Open
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