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Bone metastasis patterns in solid cancers at a tertiary cancer center. 三级肿瘤中心实体癌的骨转移模式。
Pub Date : 2025-11-01
L C Rosas, D Y García-Ortega, M A Clara-Altamirano, H Martínez-Said, V Villavicencio-Valencia, A P Meléndez-Fernández, R E González-Prieto, C González-Álvarez, M Cuellar-Hubbe

Introduction: Metastatic Bone Cancer (MBC) is the most common malignancy affecting the skeletal system. The cancers that most frequently metastasize to bone include breast, prostate, lung, kidney, and thyroid cancers (comprising 70% of cases). Metastatic patterns are classified as lytic, blastic, or mixed lesions, often affecting the axial skeleton.

Materials and methods: this retrospective cohort study included patients with MBC treated between January 1, 2012, and December 31, 2022. Patients over 17 years of age with a diagnosis of solid neoplasia and evidence of metastatic bone disease confirmed by plain radiographs, computed tomography, magnetic resonance imaging, or PET-CT were included. Patients who died from causes unrelated to cancer and those who discontinued follow-up were excluded. Statistical analysis: we performed a descriptive analysis of demographic variables and used a Cox regression model, incorporating variables adapted to the model. Overall Survival (OS) was evaluated using the Kaplan-Meier method.

Results: we analyzed data from 902 patients with a median age of 61 years. The majority were male (54.4%). Multiple lesions (three or more) were found in 49% of cases, primarily in the axial skeleton. Prostate cancer was the most common primary cancer (32%), while lytic lesions were most often associated with lung cancer (38%). Additionally, 153 patients (17%) had pathological fractures, 77% experienced pain secondary to Hypercalcemia of Malignancy (HCM), and 59% had metastases in organs other than bone. The median OS was 15 months.

Conclusions: bone metastases are a poor prognostic factor in cancer patients and negatively impact quality of life. Identifying and understanding metastatic patterns is essential for developing effective therapeutic strategies and innovative treatments.

转移性骨癌(MBC)是影响骨骼系统的最常见的恶性肿瘤。最常转移到骨的癌症包括乳腺癌、前列腺癌、肺癌、肾癌和甲状腺癌(占病例的70%)。转移类型可分为溶解性、成母性或混合性病变,常影响中轴骨骼。材料和方法:本回顾性队列研究纳入2012年1月1日至2022年12月31日期间接受治疗的MBC患者。患者年龄超过17岁,经x线平片、计算机断层扫描、磁共振成像或PET-CT证实为实体瘤变和转移性骨病。死于与癌症无关的原因的患者和停止随访的患者被排除在外。统计分析:我们对人口统计变量进行了描述性分析,并使用了Cox回归模型,纳入了适应该模型的变量。采用Kaplan-Meier法评估总生存期(OS)。结果:我们分析了902例患者的数据,中位年龄为61岁。男性居多(54.4%)。49%的病例发现多发病变(三个或更多),主要发生在中轴骨骼。前列腺癌是最常见的原发癌(32%),而溶解性病变最常与肺癌相关(38%)。此外,153名患者(17%)有病理性骨折,77%的患者经历了恶性高钙血症(HCM)继发的疼痛,59%的患者有骨以外器官转移。中位生存期为15个月。结论:骨转移是癌症患者预后不良的因素,并对生活质量产生负面影响。识别和理解转移模式对于制定有效的治疗策略和创新治疗至关重要。
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引用次数: 0
Sequelae of an acute Essex Lopresti lesion: a case report. 急性Essex Lopresti病变的后遗症:1例报告。
Pub Date : 2025-09-01
R Maroto-Rodríguez, M Pérez-Abad, M Tibau-Alberdi, A Pérez-Prieto, A Ferreres

Introduction: the forearm is considered a joint in itself where the ulna and radius interact. It is composed of the proximal radioulnar joint (PRUJ), the interosseous membrane (IOM), with the central band as the main component, and the distal radioulnar joint (DRUJ), which includes the triangular fibrocartilage complex (TFCC). Essex-Lopresti lesion (ELL) is a complex injury caused by axial forearm loading, leading to longitudinal radioulnar dissociation and stability loss due to IOM rupture, PRUJ injury with radial head involvement, and DRUJ injury with TFCC involvement. Early diagnosis is crucial as treating chronic injuries poses a significant challenge.

Objective: to describe chronic ELL, review the literature, and share treatment experience.

Case presentation: we describe the case of a 30-year-old male patient with a history of a motorcycle accident in 2019, initially diagnosed as a comminuted radial head fracture and treated with its resection at another center. He presented to our center in June 2023, complaining of wrist pain and a reducible but unstable dorsal ulnar protrusion. He had no elbow or forearm pain and had a full range of motion. Complementary tests (X-rays, CT scans, and MRI) showed a positive ulnar variance, a dorsal ulnar subluxation at the wrist and a TFCC lesion, without evidence of acute rupture of the IOM. An examination under anesthesia and fluoroscopic evaluation was performed to examine the stability and range of motion of the elbow and ARCD, as well as longitudinal stability of the forearm by traction, with no longitudinal instability observed. After considering the longitudinal stability of the forearm A 10 mm ulnar shortening osteotomy was performed and fixed with a plate and screws (FreeFix® SKDynamics). Arthroscopically, the TFCC was disinserted and reinserted using a modification of the Mantovani technique. It was immobilized with a Münster splint. At six-month follow-up, he has a VAS of 0 at the elbow and wrist, and a dorsal flexion/ volar flexion of 80o/80o, and a supination/pronation deficit of 10o/10o.

Conclusion: ELL is a rare but challenging pathology for orthopaedic surgeons. Therapeutic options include various surgical interventions, with ulnar shortening with TFCC repair being a viable option in chronic cases without longitudinal instability.

简介:前臂本身被认为是尺骨和桡骨相互作用的关节。它由近端尺桡关节(PRUJ)、骨间膜(IOM)和远端尺桡关节(DRUJ)组成,其中包括三角形纤维软骨复合体(TFCC)。essei - lopresti损伤(ELL)是前臂轴向负荷引起的复杂损伤,IOM破裂导致纵向尺桡分离和稳定性丧失,PRUJ损伤伴桡骨头受累,DRUJ损伤伴TFCC受累。早期诊断是至关重要的,因为治疗慢性损伤是一项重大挑战。目的:描述慢性ELL,回顾文献,分享治疗经验。病例介绍:我们描述了一名30岁男性患者的病例,该患者于2019年发生摩托车事故,最初诊断为粉碎性桡骨头骨折,并在另一个中心进行了手术切除。他于2023年6月到我们中心就诊,主诉手腕疼痛和可复位但不稳定的尺背突出。他没有肘部或前臂疼痛,活动范围很广。辅助检查(x射线、CT扫描和MRI)显示尺侧变异阳性,腕部尺背半脱位和TFCC病变,无IOM急性破裂的证据。在麻醉和透视下检查肘关节和ARCD的稳定性和活动范围,以及牵引前臂的纵向稳定性,未观察到纵向不稳定。在考虑前臂的纵向稳定性后,进行10mm尺侧截骨术,并用钢板和螺钉(FreeFix®SKDynamics)固定。关节镜下,使用改良的Mantovani技术将TFCC拔出并重新插入。用内斯特夹板固定。在6个月的随访中,他的肘关节和手腕的VAS为0,背屈/掌屈为80度/80度,旋前/旋前不足100度/ 100度。结论:ELL是一种罕见但具有挑战性的骨科病理。治疗选择包括各种手术干预,在没有纵向不稳定的慢性病例中,尺骨缩短与TFCC修复是一种可行的选择。
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引用次数: 0
[Staphylococcus aureus carriers in hip and knee arthroplasty. Effectiveness of decolonization and prevention of periprosthetic infections]. 髋关节和膝关节置换术中的金黄色葡萄球菌携带者。非殖民化和预防假体周围感染的有效性[j]。
Pub Date : 2025-09-01
W F Martínez, L Camacho-Terceros, F Garbini, E J Bochatey, F A Lopreite

Introduction: the impact of preoperative screening and the effectiveness of targeted decolonization in carriers of Staphylococcus aureus (SA) on the prevalence of acute periprosthetic infections (PJI) in patients undergoing hip and knee arthroplasty was evaluated.

Material and methods: analytical, observational, case-control, ambispective and consecutive study. 256 patients were included for hip and knee prosthetic surgery between January 2020 and December 2022. Those who underwent surgery in the period prior to the pre-surgical search for S. Aureus were called pre-intervention group (G1) between January 2020 and June of 2021, and those intervened in the search and decolonization called intervention group (G2) between July 2021 to December 2022. In G2, SA carriage and the effectiveness of bacterial decolonization were evaluated. The prevalence of periprosthetic infection due to this germ in both groups was also compared.

Results: the prevalence of nasal and inguinal colonization for MSSA was 25.8% and that of MRSA was 2.3%. Preoperative decolonization therapy in SA carriers was associated with a reduction in the rate of periprosthetic infections.

Conclusions: the incidence Staphylococcus aureus carriers in patients scheduled for hip and knee arthroplasty was high. Preoperative detection of S. aureus with targeted decolonization therapy was associated with a reduction in periprosthetic infections mediated.

前言:评估术前筛查和靶向去菌落金黄色葡萄球菌(SA)携带者对髋关节和膝关节置换术患者急性假体周围感染(PJI)患病率的影响。材料和方法:分析性研究、观察性研究、病例对照研究、双视角研究和连续研究。在2020年1月至2022年12月期间,256名患者接受了髋关节和膝关节假体手术。在2020年1月至2021年6月期间,在术前搜索金黄色葡萄球菌之前接受手术的患者称为干预前组(G1),而在2021年7月至2022年12月期间进行搜索和非殖民化干预的患者称为干预组(G2)。在G2中,评估SA的携带和细菌去定殖的有效性。两组患者假体周围感染的发生率也进行了比较。结果:鼻腔和腹股沟定植MSSA为25.8%,MRSA为2.3%。SA携带者术前去菌落治疗与假体周围感染率的降低相关。结论:髋关节置换术患者中金黄色葡萄球菌携带者的发生率较高。术前检测金黄色葡萄球菌与靶向去殖民化治疗与假体周围感染介导的减少相关。
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引用次数: 0
Endoscopic gluteus maximus release for peritrochanteric decompression. 内窥镜下臀大肌松解术用于转子周围减压。
Pub Date : 2025-09-01
D Seidel-Carrera, C Tobar-Parra, J F Castillo-Saenz, D Parodi-Sanguesa

Introduction: peritrochanteric syndrome, also known as greater trochanteric pain syndrome, affects 10-25% of the population, resulting in pain and functional impairment in the lateral hip region. This condition is often associated with significant long-term disabilities.

Objective: this study aims to introduce a novel surgical approach for treating peritrochanteric syndrome that minimizes invasiveness and enhances patient outcomes.

Material and methods: we describe a technique that utilizes customized portals through the iliotibial band (ITB) along with the release of the proximal insertion of the gluteus maximus (GM). Patients are positioned supine, with access to the peritrochanteric space achieved through a 70° arthroscope. Radiofrequency release of approximately 3-4 cm of the distal GM insertion is performed to alleviate pressure and reduce friction in the peritrochanteric space.

Conclusion: the proposed surgical method offers a promising alternative to traditional approaches for treating peritrochanteric syndrome by minimizing the tissue trauma and enhancing recovery. Further research is necessary to evaluate the long-term efficacy and safety of this innovative intervention in a larger patient population.

转子周围综合征,又称大转子疼痛综合征,影响10-25%的人群,导致髋外侧区疼痛和功能障碍。这种情况通常与严重的长期残疾有关。目的:本研究旨在介绍一种治疗转子周围综合征的新手术方法,以减少侵入性并提高患者的预后。材料和方法:我们描述了一种技术,利用通过髂胫束(ITB)的定制门户,同时释放臀大肌(GM)的近端止点。患者仰卧位,通过70°关节镜进入股骨粗隆周围间隙。射频释放远端GM插入物约3-4厘米,以减轻转子周围空间的压力和减少摩擦。结论:与传统方法相比,该方法可减少组织损伤,促进康复,是治疗股骨粗隆周围综合征的理想方法。需要进一步的研究来评估这种创新干预在更大患者群体中的长期疗效和安全性。
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引用次数: 0
Partial meniscectomy recovery time for work return, not as fast as we believe. 半月板部分切除后恢复工作的时间,并没有我们想象的那么快。
Pub Date : 2025-09-01
J M Rodríguez-Roiz, J Montañana-Burillo, F Rodríguez-Verdugo, C Medrano-Nájera, J S Sánchez-Díaz

Introduction: the objective of our work is to assess the timeline of return to work (RTW) and sports, following arthroscopic partial meniscectomy. We hypothesized that patients in greater-intensity occupations would demonstrate greater duration of absence from work and sports, and also that most patients return to unrestricted activity within 7 weeks after knee arthroscopy.

Material and methods: we obtained from 100 cases preop Tegner, Lysholm, VAS and type of work based on physical demand (REFA classification). We reevaluate all cases at three months and at two years postop.

Results: all the patients returned to work, and 90% returned to sports. The median RTW time was 4.8 months. 79% RTW by six months. Of the 21 patients with no subjective improvement by six months, seven required revision knee arthroscopy, 14 had biomechanical examinations that showed submaximal effort and they returned to work. We evaluated type of meniscal tear, gender, age, Lysholm score, Tegner, VAS, satisfaction with knee results postop and rehabilitation sessions, and we did not find any statistically significant correlation with RTW time.

Conclusion: we thought RTW after meniscal surgery strongly depends on the physical work strain, but we didn't find that in our study. So, we taught much more variables influences on work return, and worker compensation has an important value.

简介:我们的工作目的是评估关节镜半月板部分切除术后恢复工作(RTW)和运动的时间。我们假设,从事高强度职业的患者在工作和运动中缺席的时间更长,并且大多数患者在膝关节镜检查后7周内恢复无限制活动。材料和方法:我们收集了100例术前Tegner, Lysholm, VAS和基于体力需求的工作类型(REFA分类)。我们在术后3个月和2年重新评估所有病例。结果:所有患者恢复工作,90%的患者恢复运动。中位中转时间为4.8个月。79%的人提前6个月返航。在21名患者中,6个月没有主观改善,7名患者需要进行膝关节镜检查,14名进行生物力学检查,显示次最大的努力,他们恢复了工作。我们评估了半月板撕裂类型、性别、年龄、Lysholm评分、Tegner评分、VAS评分、术后和康复期间膝关节结果满意度,我们没有发现与RTW时间有统计学意义的相关性。结论:我们认为半月板手术后的RTW与体力劳动应变有很大关系,但在我们的研究中并没有发现这一点。因此,我们了解到影响劳动报酬的变量很多,而劳动者报酬具有重要的价值。
{"title":"Partial meniscectomy recovery time for work return, not as fast as we believe.","authors":"J M Rodríguez-Roiz, J Montañana-Burillo, F Rodríguez-Verdugo, C Medrano-Nájera, J S Sánchez-Díaz","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>the objective of our work is to assess the timeline of return to work (RTW) and sports, following arthroscopic partial meniscectomy. We hypothesized that patients in greater-intensity occupations would demonstrate greater duration of absence from work and sports, and also that most patients return to unrestricted activity within 7 weeks after knee arthroscopy.</p><p><strong>Material and methods: </strong>we obtained from 100 cases preop Tegner, Lysholm, VAS and type of work based on physical demand (REFA classification). We reevaluate all cases at three months and at two years postop.</p><p><strong>Results: </strong>all the patients returned to work, and 90% returned to sports. The median RTW time was 4.8 months. 79% RTW by six months. Of the 21 patients with no subjective improvement by six months, seven required revision knee arthroscopy, 14 had biomechanical examinations that showed submaximal effort and they returned to work. We evaluated type of meniscal tear, gender, age, Lysholm score, Tegner, VAS, satisfaction with knee results postop and rehabilitation sessions, and we did not find any statistically significant correlation with RTW time.</p><p><strong>Conclusion: </strong>we thought RTW after meniscal surgery strongly depends on the physical work strain, but we didn't find that in our study. So, we taught much more variables influences on work return, and worker compensation has an important value.</p>","PeriodicalId":101296,"journal":{"name":"Acta ortopedica mexicana","volume":"39 5","pages":"287-291"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145575167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Persistent myxoinflammatory fibroblastic sarcoma: an unusual case report and literature review]. 【持续性黏液炎性纤维母细胞肉瘤:罕见病例报告及文献复习】。
Pub Date : 2025-09-01
J G Ugalde-Fuentes, G L Alcántara-Ramos

Introduction: myxoinflammatory fibroblastic sarcoma is a rare type of sarcoma characterized by the abnormal growth of mesenchymal tissue. It is known for its locally aggressive behavior, high recurrence rate, and potential for metastasis. Clinically, it typically presents as a superficial, painless subcutaneous mass, although it may sometimes cause pain and restricted movement. Histologically, comprises spindle cells with myxoid stroma and large atypical cells with marked nuclear pleomorphism, similar to Reed-Sternberg cells.

Case presentation: an 83-year-old woman presented with a lesion on the anterior region of her left leg. A comprehensive study protocol for a musculoskeletal tumor was initiated, followed by an incisional biopsy for histological and immunohistochemical analysis, which led to the diagnosis of myxoinflammatory fibroblastic sarcoma. The tumor was surgically resected, and the intraoperative and final report indicated negative surgical margins.

Results: the patient experienced a favorable recovery and regained full mobility. Despite initial treatment and recovery, signs of local persistence were observed during follow-up four months later. The patient opted not to pursue the recommended treatment, choosing instead to continue monitoring the lesion.

Conclusions: this case underscores the importance of including myxoinflammatory fibroblastic sarcoma in the differential diagnosis of musculoskeletal lesions and highlights the need for multidisciplinary collaboration for accurate diagnosis and effective treatment.

黏液炎性纤维母细胞肉瘤是一种罕见的肉瘤,其特征是间充质组织的异常生长。众所周知,它具有局部侵袭性,高复发率和转移潜力。临床上,它通常表现为浅表无痛的皮下肿块,尽管有时可能引起疼痛和活动受限。组织学上,包括具有黏液样基质的梭形细胞和具有明显核多形性的大型非典型细胞,类似于Reed-Sternberg细胞。病例介绍:一名83岁女性,左腿前侧出现病变。一项针对肌肉骨骼肿瘤的综合研究方案被启动,随后进行了切口活检进行组织学和免疫组织化学分析,最终诊断为黏液炎性纤维母细胞肉瘤。手术切除肿瘤,术中和最终报告显示阴性手术切缘。结果:患者恢复良好,可完全活动。尽管最初的治疗和恢复,在四个月后的随访中观察到局部持续的迹象。患者选择不进行推荐的治疗,而是选择继续监测病变。结论:该病例强调了将黏液炎性纤维母细胞肉瘤纳入肌肉骨骼病变鉴别诊断的重要性,并强调了多学科合作对准确诊断和有效治疗的必要性。
{"title":"[Persistent myxoinflammatory fibroblastic sarcoma: an unusual case report and literature review].","authors":"J G Ugalde-Fuentes, G L Alcántara-Ramos","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>myxoinflammatory fibroblastic sarcoma is a rare type of sarcoma characterized by the abnormal growth of mesenchymal tissue. It is known for its locally aggressive behavior, high recurrence rate, and potential for metastasis. Clinically, it typically presents as a superficial, painless subcutaneous mass, although it may sometimes cause pain and restricted movement. Histologically, comprises spindle cells with myxoid stroma and large atypical cells with marked nuclear pleomorphism, similar to Reed-Sternberg cells.</p><p><strong>Case presentation: </strong>an 83-year-old woman presented with a lesion on the anterior region of her left leg. A comprehensive study protocol for a musculoskeletal tumor was initiated, followed by an incisional biopsy for histological and immunohistochemical analysis, which led to the diagnosis of myxoinflammatory fibroblastic sarcoma. The tumor was surgically resected, and the intraoperative and final report indicated negative surgical margins.</p><p><strong>Results: </strong>the patient experienced a favorable recovery and regained full mobility. Despite initial treatment and recovery, signs of local persistence were observed during follow-up four months later. The patient opted not to pursue the recommended treatment, choosing instead to continue monitoring the lesion.</p><p><strong>Conclusions: </strong>this case underscores the importance of including myxoinflammatory fibroblastic sarcoma in the differential diagnosis of musculoskeletal lesions and highlights the need for multidisciplinary collaboration for accurate diagnosis and effective treatment.</p>","PeriodicalId":101296,"journal":{"name":"Acta ortopedica mexicana","volume":"39 5","pages":"313-318"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145575176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Gut microbiota and osteoarthritis: a new therapeutic frontier in orthopedics]. 肠道微生物群与骨关节炎:骨科治疗的新前沿。
Pub Date : 2025-09-01
M I Encalada-Díaz

No Abstract available.

没有摘要可用。
{"title":"[Gut microbiota and osteoarthritis: a new therapeutic frontier in orthopedics].","authors":"M I Encalada-Díaz","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>No Abstract available.</p>","PeriodicalId":101296,"journal":{"name":"Acta ortopedica mexicana","volume":"39 5","pages":"335"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145575192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Cemented total knee arthroplasty with mobile bearing for the treatment of primary gonarthrosis: is it a solid treatment option? Long-term follow-up]. 带活动轴承的骨水泥全膝关节置换术治疗原发性膝关节炎:这是一种可靠的治疗选择吗?长期随访。
Pub Date : 2025-09-01
D A Ramos-Murillo, P A Ramos-Guarderas, G F Arteaga-Guerrero, M X Vargas-Morante, P D Ramos-Murillo, C P Peñaherrera-Carrillo, F Endara-Uresta, A X Barros-Castro, P S Vaca-Pérez

Introduction: Total Knee Arthroplasty (TKA) is one of the most frequently performed orthopedic interventions worldwide, with more than 700,000 primary procedures conducted in 2013. This study aims to demonstrate that TKA with cemented components and mobile bearings is a solid treatment option with low complication rates, good clinical outcomes, and adequate long-term survival.

Materials and methods: this retrospective study included 890 cases in 810 patients diagnosed with grade IV gonarthrosis, with a mean age of 67.80 years and a mean follow-up period of 12.5 years. Joint replacement was performed using the Langenbeck approach. Evaluation was both radiological and functional, using the American Knee Society Score (AKSS) and Oxford Knee Score (OKS) scales to demonstrate long-term results.

Results: the preoperative clinical AKSS was 58.7, and 94.4 points at 14 years; the preoperative functional AKSS was 56.73, and 72.5 points at 14 years; and the preoperative OKS was 26.77, and 44.2 points at 14 years, with a cumulative survival rate of 98.0% at 14 years, using revision for any reason as the primary endpoint.

Conclusion: TKA with mobile bearings for the treatment of grade IV gonarthrosis shows favorable functional outcomes, high long-term survival rates, and low complication rates.

全膝关节置换术(TKA)是世界范围内最常用的骨科干预措施之一,2013年进行了超过70万例初级手术。本研究旨在证明TKA与骨水泥组件和活动轴承是一种可靠的治疗选择,并发症发生率低,临床结果好,长期生存率高。材料与方法:本回顾性研究纳入810例诊断为IV级关节病的890例患者,平均年龄67.80岁,平均随访12.5年。采用Langenbeck入路进行关节置换术。评估包括放射学和功能,使用美国膝关节协会评分(AKSS)和牛津膝关节评分(OKS)量表来证明长期效果。结果:术前临床AKSS为58.7分,14岁时为94.4分;术前功能性AKSS为56.73分,14岁时为72.5分;术前OKS为26.77,14年时为44.2分,14年时的累积生存率为98.0%,以任何原因的翻修作为主要终点。结论:活动轴承TKA治疗IV级关节病具有良好的功能预后、高的长期生存率和低的并发症发生率。
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引用次数: 0
[Localized tenosynovial giant cell tumor of the knee. Case report]. 膝关节局部腱鞘巨细胞瘤。病例报告)。
Pub Date : 2025-09-01
R Velázquez-Castañeda, G Fraind-Maya, R J Pérez-Arce, J Lassard-Rosenthal, R García-Linage, D Zimbrón-López

Introduction: tenosynovial giant cell tumor (TGCT) is a rare benign neoplastic condition affecting joint synovia, bursae, and tendon sheaths. It is classified as localized or diffuse based on clinical and biological behavior. Localized forms often affect small joints like fingers (85%), while diffuse forms primarily involve large joints, particularly the knee. Diffuse forms are more aggressive and can exceptionally exhibit malignancy.

Case report: a 27-year-old male presented with a 2-year history of intermittent knee locking and reduced mobility, worsening after a sports-related trauma. MRI showed hyperintense nodular lesions in the posterior capsule of the knee. Arthroscopy confirmed a mass adherent to the posterior capsule, which was excised and pathologically diagnosed as localized TGCT. The patient was discharged home without complications 24 hours' post-surgery, and a 6-month follow-up MRI showed no significant findings. Currently, the patient has full range of motion and no limitations in physical activity.

Conclusions: TGCT diagnosis can be challenging due to variable presentation and nonspecific symptoms, often mimicking meniscal tears. MRI is crucial for diagnosis and surgical planning. Localized forms are managed with arthroscopic excision, yielding low recurrence rates (0-10%) and excellent outcomes. Diffuse forms may require adjuvant radiotherapy or pharmacological treatments in refractory cases.

简介:腱鞘巨细胞瘤(TGCT)是一种少见的影响关节滑膜、滑囊和肌腱鞘的良性肿瘤。根据临床和生物学行为将其分为局部或弥漫性。局部形式通常影响小关节,如手指(85%),而弥漫性形式主要涉及大关节,特别是膝关节。弥漫性肿瘤更具侵袭性,可特别表现为恶性肿瘤。病例报告:一名27岁男性,表现为2年的间歇性膝关节锁定和活动能力降低,在运动相关创伤后病情恶化。MRI显示膝关节后囊高强度结节病变。关节镜证实后囊膜附着肿块,切除后病理诊断为局限性TGCT。患者术后24小时无并发症出院,6个月的随访MRI未见明显发现。目前,患者活动范围全,身体活动无限制。结论:TGCT诊断可能具有挑战性,因为其表现多变且非特异性症状,通常类似半月板撕裂。MRI对诊断和手术计划至关重要。局部形式通过关节镜切除治疗,复发率低(0-10%),预后良好。弥漫性形式可能需要辅助放疗或药物治疗难治性病例。
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引用次数: 0
[Prescription pattern in the decision of early amputation of a severely injured limb in a referral trauma hospital]. [转诊创伤医院重症肢体早期截肢决定的处方模式]。
Pub Date : 2025-09-01
S Gaytán-Fernández, M A Aceves-Martínez, J Quiroz-Williams, R G Barragán-Hervella, A Fernández-Rivera, L López-Meléndez, S Bautista-Martínez, J A Cruz-Ricardez

Introduction: the decision to amputate a severely injured limb is a dilemma for any orthopedic surgeon. There are multiple factors for this decision, being controversial for decision making.

Objective: to know the type of prescription pattern for decision-making in early amputation of a severely injured limb in a reference trauma hospital.

Material and methods: analytical, cross-sectional and prospective observational study. Orthopedic surgeons and resident physicians in the orthopedic specialty were evaluated, who evaluated five clinical cases of severely injured limbs, and through MESS, decided whether to amputate the limb. The statistic used was 2 to assess the coincidence of the decisions with the experts' responses, and Odds Ratio to estimate risks. The value that was taken as statistically significant was p < 0.005.

Results: sample 81 participants, 64.2% OB and 35.8% MR. The agreement of responses with the group of experts, OB was 85.4% and MR was 70%. In the OB, work experience had a higher percentage of coincidences, but they were not statistically significant (> 20 years, p = 0.034; 10-19 years, p = 0.011; < 9 years, p = 0.011) on the other hand, presenting a current certification (p = 0.002) and have a postgraduate degree after the specialty (p = 0.006) if they had one when compared with the responses of the group of experts.

Conclusions: in all the physician surveyed, the correct application of MESS, they had a great agreement in the correct decision to save or amputate a severely damaged limb.

对任何整形外科医生来说,决定切除严重受伤的肢体都是一个难题。这个决定有多种因素,在决策过程中存在争议。目的:了解某参考创伤医院重型肢体早期截肢手术的处方模式类型。材料和方法:分析性、横断面性和前瞻性观察性研究。评估骨科专科的骨科外科医生和住院医师,他们对5例严重肢体损伤的临床病例进行评估,并通过MESS决定是否截肢。使用的统计量是2来评估决策与专家的反应的一致性,并使用Odds Ratio来评估风险。以p < 0.005为差异有统计学意义。结果:81名被调查者中,OB为64.2%,MR为35.8%。与专家组的回答一致,OB为85.4%,MR为70%。在OB组中,工作经验的符合率较高,但没有统计学意义(> 20年,p = 0.034; 10-19年,p = 0.011; < 9年,p = 0.011),另一方面,与专家组的回答相比,如果他们有目前的认证(p = 0.002),如果他们有专业后的研究生学位(p = 0.006)。结论:在接受调查的所有医师中,正确应用MESS,他们在正确决定挽救或截肢严重损伤肢体方面有很大的一致性。
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引用次数: 0
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Acta ortopedica mexicana
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