Pub Date : 2021-06-01DOI: 10.32756/0869-5490-2021-2-51-58
R. Gorenkov, L.V. Iwanitsky, I. V. Pozharov, E. Kurbatova, I.V. Obedkov, T. Chernyavskaya, E. Kakorina
he article reviews the definition of medical telepatronage, its tasks, functions, efficiency and perspectives of implementation into the clinical practice. The main goals of telepatronage are therapeutic and preventive measures based on the remote interaction of health care practioner with a patient. Telepatronage includes remote observation of the patient, self-monitoring of the disease and prescrtiptions, patient motivation and education on the digital Web 2.0 platform, and the creation of a remote coordination center. The authors present their own experience in remote monitoring of patients with rheumatic diseases, which is planned to be expanded to create a medical telepatronage system.
{"title":"Medical telepatronage as a health-saving technology in the management of patients with chronic non-communicable diseases","authors":"R. Gorenkov, L.V. Iwanitsky, I. V. Pozharov, E. Kurbatova, I.V. Obedkov, T. Chernyavskaya, E. Kakorina","doi":"10.32756/0869-5490-2021-2-51-58","DOIUrl":"https://doi.org/10.32756/0869-5490-2021-2-51-58","url":null,"abstract":"he article reviews the definition of medical telepatronage, its tasks, functions, efficiency and perspectives of implementation into the clinical practice. The main goals of telepatronage are therapeutic and preventive measures based on the remote interaction of health care practioner with a patient. Telepatronage includes remote observation of the patient, self-monitoring of the disease and prescrtiptions, patient motivation and education on the digital Web 2.0 platform, and the creation of a remote coordination center. The authors present their own experience in remote monitoring of patients with rheumatic diseases, which is planned to be expanded to create a medical telepatronage system.","PeriodicalId":10353,"journal":{"name":"Clinical pharmacology and therapy","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79778691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-01DOI: 10.32756/0869-5490-2021-2-17-21
A. Petrosyan, M. Diane, E. Kotova
The authors review approaches to the early prediction of cardiovascular diseases in patients with type 1 diabetes mellitus, e.g. using central arterial pressure, arterial stiffness, and a loss of arterial stiffness gradient. The bulk of data was presented either on diabetes mellitus in general or on type 2 diabetes mellitus, while there is a clear gap in information on type 1 diabetes mellitus. The study of the elastic properties of the vascular bed in these patients can become the basis for the early prevention of cardiovascular complications.
{"title":"Early prediction of cardiovascular disease in patients with type 1 diabetes","authors":"A. Petrosyan, M. Diane, E. Kotova","doi":"10.32756/0869-5490-2021-2-17-21","DOIUrl":"https://doi.org/10.32756/0869-5490-2021-2-17-21","url":null,"abstract":"The authors review approaches to the early prediction of cardiovascular diseases in patients with type 1 diabetes mellitus, e.g. using central arterial pressure, arterial stiffness, and a loss of arterial stiffness gradient. The bulk of data was presented either on diabetes mellitus in general or on type 2 diabetes mellitus, while there is a clear gap in information on type 1 diabetes mellitus. The study of the elastic properties of the vascular bed in these patients can become the basis for the early prevention of cardiovascular complications.","PeriodicalId":10353,"journal":{"name":"Clinical pharmacology and therapy","volume":"295 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76131145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-01DOI: 10.32756/0869-5490-2021-2-75-80
D. V. Ivaschenko, L. Fedina, D.A. Yudelievich, N. Buromskaya, P. V. Shimanov, R. V. Deitsch, I. V. Dorina, K. Akmalova, A. Kachanova, E. Grishina, L. Savchenko, Y. Shevchenko, D. Sychev
The prospective observational study included 101 adolescents diagnosed with acute polymorphic psychotic disorder at the time of admission. Patients were followed up for 14 days. All patients received an antipsychotic as their main therapy. The following scales were used to assess the efficacy and safety of therapy on day 14: CGAS, PANSS, CGI-S, CGI-I, UKU SERS, SAS, BARS. The determination of polymorphic variants of DRD2 (rs1800497, C>T), DRD3 (rs6280, C>T), DRD3 (rs324026, C>T), and DRD4 (rs1800955, C>T) genes was performed by real-time polymerase chain reaction (PCR).
{"title":"The polymorphic variants DRD2, DRD3, and DRD4 are associated with early efficacy and safety of antipsychotics in adolescents with an acute psychotic episode","authors":"D. V. Ivaschenko, L. Fedina, D.A. Yudelievich, N. Buromskaya, P. V. Shimanov, R. V. Deitsch, I. V. Dorina, K. Akmalova, A. Kachanova, E. Grishina, L. Savchenko, Y. Shevchenko, D. Sychev","doi":"10.32756/0869-5490-2021-2-75-80","DOIUrl":"https://doi.org/10.32756/0869-5490-2021-2-75-80","url":null,"abstract":"The prospective observational study included 101 adolescents diagnosed with acute polymorphic psychotic disorder at the time of admission. Patients were followed up for 14 days. All patients received an antipsychotic as their main therapy. The following scales were used to assess the efficacy and safety of therapy on day 14: CGAS, PANSS, CGI-S, CGI-I, UKU SERS, SAS, BARS. The determination of polymorphic variants of DRD2 (rs1800497, C>T), DRD3 (rs6280, C>T), DRD3 (rs324026, C>T), and DRD4 (rs1800955, C>T) genes was performed by real-time polymerase chain reaction (PCR).","PeriodicalId":10353,"journal":{"name":"Clinical pharmacology and therapy","volume":"236 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85141078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-11-15DOI: 10.32756/0869-5490-2020-4-61-66
V. A. Aliyeva
According to the World Health Organisation (WHO) report, over the last 40 years there was an almost three-fold increase in the prevalence of obesity across the world. During the same period the frequence of obesity in children and adolescents aged 5 to 19 years increased from 1% up to 7%. WHO reported that 65% of the world's population live in countries where overweight and obesity kills more people than underweight. Obesity is associated with various chronic diseases, such as type 2 diabetes, dyslipidemia, and arterial hypertension that increase the risk of disability and death. In patients with obesity, life expectancy is reduced by 15 years compared to individuals with normal body weight. Obesity and associated comorbidities significantly increase healthcare costs. The goals of treatment for obesity should include both weight loss and improvement of glucose and lipid metabolism, hemostasis, etc. The author reviews the current anti-obesity medications that can be used for weight loss.
{"title":"Current pharmacotherapy for obesity","authors":"V. A. Aliyeva","doi":"10.32756/0869-5490-2020-4-61-66","DOIUrl":"https://doi.org/10.32756/0869-5490-2020-4-61-66","url":null,"abstract":"According to the World Health Organisation (WHO) report, over the last 40 years there was an almost three-fold increase in the prevalence of obesity across the world. During the same period the frequence of obesity in children and adolescents aged 5 to 19 years increased from 1% up to 7%. WHO reported that 65% of the world's population live in countries where overweight and obesity kills more people than underweight. Obesity is associated with various chronic diseases, such as type 2 diabetes, dyslipidemia, and arterial hypertension that increase the risk of disability and death. In patients with obesity, life expectancy is reduced by 15 years compared to individuals with normal body weight. Obesity and associated comorbidities significantly increase healthcare costs. The goals of treatment for obesity should include both weight loss and improvement of glucose and lipid metabolism, hemostasis, etc. The author reviews the current anti-obesity medications that can be used for weight loss.","PeriodicalId":10353,"journal":{"name":"Clinical pharmacology and therapy","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81132217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-11-15DOI: 10.32756/0869-5490-2020-4-49-60
V. Rameev, L. Lysenko (Kozlovskaya), M. Bogdanova, S. Moiseev
Autoinflammatory diseases are a group of disorders caused by a dysregulation of the innate immune system. Unlike autoimmune diseases, they are not associated with changes in humoral or cellular immunity. The authors review the current classification, clinical manifestations and treatment of various systemic autoinflammatory diseases, including cryopirinassociated periodic syndrome, familial Mediterranean fever, HIDS, and TRAPS.
{"title":"Autoinflammatory diseases","authors":"V. Rameev, L. Lysenko (Kozlovskaya), M. Bogdanova, S. Moiseev","doi":"10.32756/0869-5490-2020-4-49-60","DOIUrl":"https://doi.org/10.32756/0869-5490-2020-4-49-60","url":null,"abstract":"Autoinflammatory diseases are a group of disorders caused by a dysregulation of the innate immune system. Unlike autoimmune diseases, they are not associated with changes in humoral or cellular immunity. The authors review the current classification, clinical manifestations and treatment of various systemic autoinflammatory diseases, including cryopirinassociated periodic syndrome, familial Mediterranean fever, HIDS, and TRAPS.","PeriodicalId":10353,"journal":{"name":"Clinical pharmacology and therapy","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79679171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-09-01DOI: 10.32756/0869-5490-2020-3-73-79
O. Ostroumova, I. Goloborodova
{"title":"Drug-induced osteoporosis","authors":"O. Ostroumova, I. Goloborodova","doi":"10.32756/0869-5490-2020-3-73-79","DOIUrl":"https://doi.org/10.32756/0869-5490-2020-3-73-79","url":null,"abstract":"","PeriodicalId":10353,"journal":{"name":"Clinical pharmacology and therapy","volume":"12 16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91442245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-05-01DOI: 10.32756/0869-5490-2020-2-77-83
P. Novikov, N. Bulanov, A. Zykova, S. Moiseev
{"title":"Mepolizumab for the treatment of eosinophilic granulomatosis with polyangiitis","authors":"P. Novikov, N. Bulanov, A. Zykova, S. Moiseev","doi":"10.32756/0869-5490-2020-2-77-83","DOIUrl":"https://doi.org/10.32756/0869-5490-2020-2-77-83","url":null,"abstract":"","PeriodicalId":10353,"journal":{"name":"Clinical pharmacology and therapy","volume":"37 6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91299489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-05-01DOI: 10.32756/0869-5490-2020-2-56-67
V. Rameev, A. Simonyan, M. Bogdanova, L. Kozlovskaya, S. Moiseev
{"title":"Familial Mediterranean fever: diagnosis and treatment","authors":"V. Rameev, A. Simonyan, M. Bogdanova, L. Kozlovskaya, S. Moiseev","doi":"10.32756/0869-5490-2020-2-56-67","DOIUrl":"https://doi.org/10.32756/0869-5490-2020-2-56-67","url":null,"abstract":"","PeriodicalId":10353,"journal":{"name":"Clinical pharmacology and therapy","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82391653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-02-20DOI: 10.32756/0869-5490-2020-1-48-52
A. Danilov, S. Kozlov, M. Slivkin
{"title":"Neurological complications of infective endocarditis","authors":"A. Danilov, S. Kozlov, M. Slivkin","doi":"10.32756/0869-5490-2020-1-48-52","DOIUrl":"https://doi.org/10.32756/0869-5490-2020-1-48-52","url":null,"abstract":"","PeriodicalId":10353,"journal":{"name":"Clinical pharmacology and therapy","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75356274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-02-20DOI: 10.32756/0869-5490-2020-1-13-24
L. Lysenko, V. Rameev, S. V. Moiseev, O. Blagova, E. Bogdanov, G. Gendlin, D. Grishina, A. Gudkova, E. Zakharova, O. E. Zinovyeva, O. Moiseeva, S. S. Nikitin, V. Parfenov, N. Suponeva, S. Tereshenko
{"title":"Clinical guidelines for diagnosis and treatment of systemic amyloidosis","authors":"L. Lysenko, V. Rameev, S. V. Moiseev, O. Blagova, E. Bogdanov, G. Gendlin, D. Grishina, A. Gudkova, E. Zakharova, O. E. Zinovyeva, O. Moiseeva, S. S. Nikitin, V. Parfenov, N. Suponeva, S. Tereshenko","doi":"10.32756/0869-5490-2020-1-13-24","DOIUrl":"https://doi.org/10.32756/0869-5490-2020-1-13-24","url":null,"abstract":"","PeriodicalId":10353,"journal":{"name":"Clinical pharmacology and therapy","volume":"71 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73648007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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