{"title":"Maladie de Wilson chez une femme de 19 ans","authors":"Stephanie E. Chan, Audrey M. Tran","doi":"10.1503/cmaj.231059-f","DOIUrl":"https://doi.org/10.1503/cmaj.231059-f","url":null,"abstract":"","PeriodicalId":10359,"journal":{"name":"CMAJ : Canadian Medical Association Journal","volume":"23 1","pages":"E421 - E424"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140352559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Une couverture publique illimitée des pharmacothérapies antitabagiques est nécessaire","authors":"Robert A. Kleinman, Peter Selby","doi":"10.1503/cmaj.231333-f","DOIUrl":"https://doi.org/10.1503/cmaj.231333-f","url":null,"abstract":"","PeriodicalId":10359,"journal":{"name":"CMAJ : Canadian Medical Association Journal","volume":"30 10","pages":"E429 - E431"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140352677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Infections of cardiac implantable electrical devices","authors":"Maxime J Billick, Orly Bogler, Wayne L. Gold","doi":"10.1503/cmaj.231121","DOIUrl":"https://doi.org/10.1503/cmaj.231121","url":null,"abstract":"","PeriodicalId":10359,"journal":{"name":"CMAJ : Canadian Medical Association Journal","volume":"29 4","pages":"E415 - E415"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140352691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shannon M. Ruzycki, Saud Sunba, M. Ejaredar, Natalie Yanchar, O. Daodu
{"title":"Addressing the root causes of the sex-based pay gap in medicine in Canada","authors":"Shannon M. Ruzycki, Saud Sunba, M. Ejaredar, Natalie Yanchar, O. Daodu","doi":"10.1503/cmaj.231518","DOIUrl":"https://doi.org/10.1503/cmaj.231518","url":null,"abstract":"","PeriodicalId":10359,"journal":{"name":"CMAJ : Canadian Medical Association Journal","volume":"775 ","pages":"E416 - E418"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140787459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Seungmi Yang, Gabriel D. Shapiro, Edward Ng, B. Vissandjée, Zoua M. Vang
Background: Most studies of disparities in birth and postnatal outcomes by parental birthplace combine all immigrants into a single group. We sought to evaluate heterogeneity among immigrants in Canada by comparing birth and postnatal outcomes across different immigration categories. Methods: We conducted a population-based retrospective study using Statistics Canada data on live births and stillbirths (1993–2017) and infant deaths (1993–2018), linked to parental immigration data (1960–2017). We classified birthing parents as born in Canada, economic-class immigrants, family-class immigrants, or refugees, and evaluated differences in preterm births, small-for-gestational-age (SGA) and large-for-gestational-age (LGA) births, stillbirths, and infant deaths among singleton births by group. Results: Among 7 980 650 births, 1 715 050 (21.5%) were to immigrants, including 632 760 (36.9%) in the economic class, 853 540 (49.8%) in the family class, and 228 740 (13.4%) refugees. Compared with infants of Canadian-born birthing parents, infants of each of the 3 immigrant groups had higher risk of preterm birth, SGA birth, and stillbirth, but lower risk of LGA birth and neonatal death. Compared with infants of economic-class immigrants, infants of refugees had higher risk of early preterm birth (0.9% v. 0.8%, adjusted risk ratio [RR] 1.08, 95% confidence interval [CI] 1.01–1.15) and LGA birth (9.2% v. 7.5%, adjusted RR 1.12, 95% CI 1.10–1.15), but lower risk of SGA birth (10.2% v. 11.0%, adjusted RR 0.92, 95% CI 0.90–0.94), while infants of family-class immigrants had higher risk of SGA birth (12.2% v. 11.0%, adjusted RR 1.01, 95% CI 1.00–1.02). Risk of stillbirth, neonatal death, and overall infant death did not differ significantly among immigrant groups. Interpretation: Heterogeneity exists in outcomes of infants born to immigrants to Canada across immigration categories. These results highlight the importance of disaggregating immigrant populations in studies of health disparities.
{"title":"Birth and postnatal outcomes among infants of immigrant parents of different admission categories and parents born in Canada: a population-based retrospective study","authors":"Seungmi Yang, Gabriel D. Shapiro, Edward Ng, B. Vissandjée, Zoua M. Vang","doi":"10.1503/cmaj.230878","DOIUrl":"https://doi.org/10.1503/cmaj.230878","url":null,"abstract":"Background: Most studies of disparities in birth and postnatal outcomes by parental birthplace combine all immigrants into a single group. We sought to evaluate heterogeneity among immigrants in Canada by comparing birth and postnatal outcomes across different immigration categories. Methods: We conducted a population-based retrospective study using Statistics Canada data on live births and stillbirths (1993–2017) and infant deaths (1993–2018), linked to parental immigration data (1960–2017). We classified birthing parents as born in Canada, economic-class immigrants, family-class immigrants, or refugees, and evaluated differences in preterm births, small-for-gestational-age (SGA) and large-for-gestational-age (LGA) births, stillbirths, and infant deaths among singleton births by group. Results: Among 7 980 650 births, 1 715 050 (21.5%) were to immigrants, including 632 760 (36.9%) in the economic class, 853 540 (49.8%) in the family class, and 228 740 (13.4%) refugees. Compared with infants of Canadian-born birthing parents, infants of each of the 3 immigrant groups had higher risk of preterm birth, SGA birth, and stillbirth, but lower risk of LGA birth and neonatal death. Compared with infants of economic-class immigrants, infants of refugees had higher risk of early preterm birth (0.9% v. 0.8%, adjusted risk ratio [RR] 1.08, 95% confidence interval [CI] 1.01–1.15) and LGA birth (9.2% v. 7.5%, adjusted RR 1.12, 95% CI 1.10–1.15), but lower risk of SGA birth (10.2% v. 11.0%, adjusted RR 0.92, 95% CI 0.90–0.94), while infants of family-class immigrants had higher risk of SGA birth (12.2% v. 11.0%, adjusted RR 1.01, 95% CI 1.00–1.02). Risk of stillbirth, neonatal death, and overall infant death did not differ significantly among immigrant groups. Interpretation: Heterogeneity exists in outcomes of infants born to immigrants to Canada across immigration categories. These results highlight the importance of disaggregating immigrant populations in studies of health disparities.","PeriodicalId":10359,"journal":{"name":"CMAJ : Canadian Medical Association Journal","volume":"28 4","pages":"E394 - E409"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140352545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sana Jawad, Carla S. Coffin, Stephen D. Vaughan, Michelle C. Lamarche
{"title":"Acute hepatitis in an 18-year-old returning traveller","authors":"Sana Jawad, Carla S. Coffin, Stephen D. Vaughan, Michelle C. Lamarche","doi":"10.1503/cmaj.230490","DOIUrl":"https://doi.org/10.1503/cmaj.230490","url":null,"abstract":"","PeriodicalId":10359,"journal":{"name":"CMAJ : Canadian Medical Association Journal","volume":"31 7","pages":"E410 - E414"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140352669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pseudohyperkaliémie en contexte de leucémie lymphoïde chronique","authors":"Patrick Gudgeon, Manoji Pereira","doi":"10.1503/cmaj.231033-f","DOIUrl":"https://doi.org/10.1503/cmaj.231033-f","url":null,"abstract":"","PeriodicalId":10359,"journal":{"name":"CMAJ : Canadian Medical Association Journal","volume":"30 1","pages":"E425 - E426"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140352684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"L’histoire de Vishma : un mystère résolu","authors":"Vishma Sookdeo, E. Etchells, Heather N. Reich","doi":"10.1503/cmaj.220302-f","DOIUrl":"https://doi.org/10.1503/cmaj.220302-f","url":null,"abstract":"","PeriodicalId":10359,"journal":{"name":"CMAJ : Canadian Medical Association Journal","volume":"106 1","pages":"E1587 - E1589"},"PeriodicalIF":0.0,"publicationDate":"2022-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80987862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Victoria G. Hall, J. Solera, Ghadeer Al-Alahmadi, Tina Marinelli, H. Cardinal, C. Poirier, Geneviève Huard, Ramesh Prasad, Sacha A. De Serres, Debra Isaac, Rahul Mainra, C. Lamarche, Ruth Sapir-Pichhadze, Susan Gilmour, Atul Humar, Deepali Kumar
Résumé Contexte: La forme grave de COVID-19 semble affecter de manière disproportionnée les gens immunovulnérables, même si les données canadiennes dans ce contexte sont limitées. Nous avons voulu déterminer quels facteurs sont associés aux paramètres de la forme grave de COVID-19 chez les receveurs de transplantations au Canada. Méthodes: Nous avons procédé à une étude de cohorte multicentrique prospective regroupant tous les receveurs d’une transplantation d’organe plein ayant reçu un diagnostic de COVID-19 suivis dans 9 programmes de transplantation au Canada entre mars 2020 et novembre 2021. Les données ont été analysées afin de dégager les facteurs de risque à l’égard du recours à l’oxygénothérapie et autres critères de la gravité de la maladie. Nous avons comparé les paramètres selon le type d’organe transplanté et suivi l’évolution des paramètres au fil du temps. Nous avons procédé à une analyse multivariée pour déterminer quelles variables sont associées au recours à l’oxygénothérapie. Résultats: En tout, 509 patients ayant reçu une transplantation d’organe plein ont contracté la COVID-19 durant la période de l’étude. Les facteurs de risque associés au recours à l’oxygénothérapie (n = 190) ou non (n = 319) incluaient l’âge (âge médian 62,6 ans, intervalle interquartile [II] 52,5–69,5 ans c. âge médian 55,5 ans, II 47,5–66,5; p < 0,001) et le nombre de comorbidités (nombre médian 3, II 2–3 c. nombre médian 2, II 1–3; p < 0,001), de même que les paramètres concernant l’immunosuppression. Les receveurs d’une transplantation pulmonaire (n = 48) étaient plus susceptibles de souffrir d’une forme grave de la maladie, avec un taux de mortalité élevé (n = 15, 31,3 %) comparativement aux receveurs d’autres organes, y compris le rein (n = 48, 14,8 %), le cœur (n = 1, 4,4 %), le foie (n = 9, 11,4 %) et le rein–pancréas (n = 3, 12,0 %) (p = 0,02). Les facteurs protecteurs contre le recours à l’oxygénothérapie incluaient le fait d’avoir subi une transplantation hépatique et de recevoir de l’azathioprine. Le fait d’avoir reçu 2 doses de vaccin anti-SRAS-CoV-2 n’a pas eu d’influence appréciable sur le recours à l’oxygénothérapie. L’analyse multivariée a montré que l’âge avancé (rapport des cotes [RC] 1,04, intervalle de confiance [IC] de 95 % 1,02–1,07) et le nombre de comorbidités (RC 1,63, IC de 95 % 1,30–2,04), entre autres facteurs, étaient associés au recours à l’oxygénothérapie. La gravité de la maladie n’a pas considérablement diminué au fil du temps. Interprétation : Malgré les progrès thérapeutiques et la vaccination des receveurs d’une transplantation d’organe plein, les signes de gravité accrue de la COVID-19, en particulier chez les receveurs d’une transplantation pulmonaire, justifient le maintien des mesures de santé publique pour protéger ces personnes à risque, et l’utilisation hâtive de traitements contre la COVID-19 chez les receveurs d’une transplantation d’organe plein.
{"title":"Gravité de la COVID-19 chez les receveurs d’une transplantation d’organe plein au Canada, 2020–2021 : étude de cohorte prospective multicentrique","authors":"Victoria G. Hall, J. Solera, Ghadeer Al-Alahmadi, Tina Marinelli, H. Cardinal, C. Poirier, Geneviève Huard, Ramesh Prasad, Sacha A. De Serres, Debra Isaac, Rahul Mainra, C. Lamarche, Ruth Sapir-Pichhadze, Susan Gilmour, Atul Humar, Deepali Kumar","doi":"10.1503/cmaj.220620-f","DOIUrl":"https://doi.org/10.1503/cmaj.220620-f","url":null,"abstract":"Résumé Contexte: La forme grave de COVID-19 semble affecter de manière disproportionnée les gens immunovulnérables, même si les données canadiennes dans ce contexte sont limitées. Nous avons voulu déterminer quels facteurs sont associés aux paramètres de la forme grave de COVID-19 chez les receveurs de transplantations au Canada. Méthodes: Nous avons procédé à une étude de cohorte multicentrique prospective regroupant tous les receveurs d’une transplantation d’organe plein ayant reçu un diagnostic de COVID-19 suivis dans 9 programmes de transplantation au Canada entre mars 2020 et novembre 2021. Les données ont été analysées afin de dégager les facteurs de risque à l’égard du recours à l’oxygénothérapie et autres critères de la gravité de la maladie. Nous avons comparé les paramètres selon le type d’organe transplanté et suivi l’évolution des paramètres au fil du temps. Nous avons procédé à une analyse multivariée pour déterminer quelles variables sont associées au recours à l’oxygénothérapie. Résultats: En tout, 509 patients ayant reçu une transplantation d’organe plein ont contracté la COVID-19 durant la période de l’étude. Les facteurs de risque associés au recours à l’oxygénothérapie (n = 190) ou non (n = 319) incluaient l’âge (âge médian 62,6 ans, intervalle interquartile [II] 52,5–69,5 ans c. âge médian 55,5 ans, II 47,5–66,5; p < 0,001) et le nombre de comorbidités (nombre médian 3, II 2–3 c. nombre médian 2, II 1–3; p < 0,001), de même que les paramètres concernant l’immunosuppression. Les receveurs d’une transplantation pulmonaire (n = 48) étaient plus susceptibles de souffrir d’une forme grave de la maladie, avec un taux de mortalité élevé (n = 15, 31,3 %) comparativement aux receveurs d’autres organes, y compris le rein (n = 48, 14,8 %), le cœur (n = 1, 4,4 %), le foie (n = 9, 11,4 %) et le rein–pancréas (n = 3, 12,0 %) (p = 0,02). Les facteurs protecteurs contre le recours à l’oxygénothérapie incluaient le fait d’avoir subi une transplantation hépatique et de recevoir de l’azathioprine. Le fait d’avoir reçu 2 doses de vaccin anti-SRAS-CoV-2 n’a pas eu d’influence appréciable sur le recours à l’oxygénothérapie. L’analyse multivariée a montré que l’âge avancé (rapport des cotes [RC] 1,04, intervalle de confiance [IC] de 95 % 1,02–1,07) et le nombre de comorbidités (RC 1,63, IC de 95 % 1,30–2,04), entre autres facteurs, étaient associés au recours à l’oxygénothérapie. La gravité de la maladie n’a pas considérablement diminué au fil du temps. Interprétation : Malgré les progrès thérapeutiques et la vaccination des receveurs d’une transplantation d’organe plein, les signes de gravité accrue de la COVID-19, en particulier chez les receveurs d’une transplantation pulmonaire, justifient le maintien des mesures de santé publique pour protéger ces personnes à risque, et l’utilisation hâtive de traitements contre la COVID-19 chez les receveurs d’une transplantation d’organe plein.","PeriodicalId":10359,"journal":{"name":"CMAJ : Canadian Medical Association Journal","volume":"26 1","pages":"E1578 - E1586"},"PeriodicalIF":0.0,"publicationDate":"2022-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80023383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prise en charge de la diverticulite aiguë","authors":"Nathan Zondervan, Ryan Snelgrove, Nori L. Bradley","doi":"10.1503/cmaj.220139-f","DOIUrl":"https://doi.org/10.1503/cmaj.220139-f","url":null,"abstract":"","PeriodicalId":10359,"journal":{"name":"CMAJ : Canadian Medical Association Journal","volume":"66 1","pages":"E1590 - E1590"},"PeriodicalIF":0.0,"publicationDate":"2022-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86119741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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