Pub Date : 2020-03-08DOI: 10.3969/J.ISSN.1004-583X.2020.01.001
Xiaonan Liang, Hui Li, Dong Wang, Xiaolan Zhang
Novel coronavirus pneumonia (NCP) is prevalent in Wuhan, Hubei province and other areas. Patients with inflammatory bowel disease (IBD) may have difficulties in medical care due to the epidemic situation, and they are more susceptible to the virus than the healthy people. In order to ensure that the IBD patients can go through the danger safely and smoothly, the IBD Group of the Chinese Medical Association Digestive Diseases Branch published the Management of Patients with Inflammatory Bowel Disease during epidemic of Novel Coronavirus Pneumonia. This paper will interpret the consensus to deepen the understanding of clinicians, patients and the related personnel. Key words: pneumonia; novel coronavirus; inflammatory bowel disease; susceptibility; management; prevention
{"title":"Interpretation of the consensus on management of patients with inflammatory bowel disease during epidemic of novel coronavirus pneumonia","authors":"Xiaonan Liang, Hui Li, Dong Wang, Xiaolan Zhang","doi":"10.3969/J.ISSN.1004-583X.2020.01.001","DOIUrl":"https://doi.org/10.3969/J.ISSN.1004-583X.2020.01.001","url":null,"abstract":"Novel coronavirus pneumonia (NCP) is prevalent in Wuhan, Hubei province and other areas. Patients with inflammatory bowel disease (IBD) may have difficulties in medical care due to the epidemic situation, and they are more susceptible to the virus than the healthy people. In order to ensure that the IBD patients can go through the danger safely and smoothly, the IBD Group of the Chinese Medical Association Digestive Diseases Branch published the Management of Patients with Inflammatory Bowel Disease during epidemic of Novel Coronavirus Pneumonia. This paper will interpret the consensus to deepen the understanding of clinicians, patients and the related personnel. \u0000 \u0000Key words: \u0000pneumonia; novel coronavirus; inflammatory bowel disease; susceptibility; management; prevention","PeriodicalId":10383,"journal":{"name":"Clinical Focus","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43468434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-03-08DOI: 10.3969/J.ISSN.1004-583X.2020.01.002
Yantian Chen, Yihua Guo, Xue-song Su
The 2019 novel coronavirus (2019-nCoV) outbreaks in China. Because of the sudden outbreak, rapid development, large scale of the epidemic and the lack of specific drug treatment, all provinces and cities of our country have launched the first-level response mechanism for major public health emergencies, which has attracted the attention of the World Health Organization(WHO). This article discusses the prevention and control measures combined with clinical experience during the outbreak of t2019-nCoV, in order to provide a reference for people from all walks of life. Key words: novel coronavirus(ncov); public health event; vaccine; antiviral drug; epidemic
{"title":"Personal prevention and control of outbreaks of 2019 novel coronavirus infection","authors":"Yantian Chen, Yihua Guo, Xue-song Su","doi":"10.3969/J.ISSN.1004-583X.2020.01.002","DOIUrl":"https://doi.org/10.3969/J.ISSN.1004-583X.2020.01.002","url":null,"abstract":"The 2019 novel coronavirus (2019-nCoV) outbreaks in China. Because of the sudden outbreak, rapid development, large scale of the epidemic and the lack of specific drug treatment, all provinces and cities of our country have launched the first-level response mechanism for major public health emergencies, which has attracted the attention of the World Health Organization(WHO). This article discusses the prevention and control measures combined with clinical experience during the outbreak of t2019-nCoV, in order to provide a reference for people from all walks of life. \u0000 \u0000Key words: \u0000novel coronavirus(ncov); public health event; vaccine; antiviral drug; epidemic","PeriodicalId":10383,"journal":{"name":"Clinical Focus","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46723714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-20DOI: 10.3969/J.ISSN.1004-583X.2020.01.009
Jianglin Xu, Liu Shangquan
{"title":"Prevalence of retinopathy and its related factors in 3 404 patients with type 2 diabetes mellitus","authors":"Jianglin Xu, Liu Shangquan","doi":"10.3969/J.ISSN.1004-583X.2020.01.009","DOIUrl":"https://doi.org/10.3969/J.ISSN.1004-583X.2020.01.009","url":null,"abstract":"","PeriodicalId":10383,"journal":{"name":"Clinical Focus","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47412179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-20DOI: 10.3969/J.ISSN.1004-583X.2020.01.005
Wang Xueshuo, Zhang Qi, L. Hua, Liu Xin, Song Da
{"title":"Effects of lowdose etibaptide combined with PCI on blood flow perfusion and cardiac function in patients with acute myocardial infarction","authors":"Wang Xueshuo, Zhang Qi, L. Hua, Liu Xin, Song Da","doi":"10.3969/J.ISSN.1004-583X.2020.01.005","DOIUrl":"https://doi.org/10.3969/J.ISSN.1004-583X.2020.01.005","url":null,"abstract":"","PeriodicalId":10383,"journal":{"name":"Clinical Focus","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49039807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-03-20DOI: 10.3760/CMA.J.ISSN.1673-4238.2010.003.006
Li-li Wang, Xiaoliang Pang, Li-Hua Wang, Dong Wang
Objective To observe the fasting glucose,serum insulin and lipid level in maintenance hemodialysis,calculate the insulin resistance index(HOMA-IR) and the insulin sensitivity index(ISI) to evaluate the relationship with insulin resistance(IR),to carry out correlation analysis with the corresponding index of 30 health examinations.Methods Forty-eight maintenance hemodialysis patients(observation group) and 30 healthy volunteers(control group) were included in this study.Fasting plasma glucose(FPG),glycosylated hemoglobin(HbA1c),fasting insulin(FIns),blood urea nitrogen(BUN),creatinine(Cr),uric acid(UA) and lipid indexes were measured,and the relationship of them analyzed.Results BUN,Cr,UA,FIns,HbA1c,FPG and HOMA-IR were significantly higher in patients than in controls,but total cholesterol(TC),high density lipid protein cholesterol(HDL-C) and low density lipid protein cholesterol(LDL-C) were significantly lower in controls,BUN(24.9±5.8) mmol/L vs(5.0±1.6) mmol/L(P0.05);Cr(820±222) μmol/L vs(73± 17) μmol/L(P0.05);UA(397±96) μmol/L vs(298±79) μmol/L(P0.05);FIns(16±11) mU/L vs(11± 5) mU/L(P0.05);FPG(6.1±1.6) mmol/L vs(5.1±0.6) mmol/L(P0.05);HOMA-IR 4.3±3.2 vs 2.4±1.2(P0.05);TC(4.2±1.2) mmol/L vs(5.3±1.1) mmol/L(P0.05);HDL-C(1.3±0.5) mmol/L vs(1.6±0.4) mmol/L(P0.01);LDL-C(3.0±1.0) mmol/L vs(4.1±1.1) mmol/L(P0.05).TC was negative correlated with FPG(r=-0.3482,P0.05).HDL-C was negative correlated with FIns(r=-0.2603,P0.05).LDL-C was negative correlated with FPG(r=-0.3289,P0.05),triglyceride was positively correlated with FPG and HOMA-IR(r=0.371,0.368,P0.05).Conclusion Lipid metabolic disorder existed in maintenance hemodialysis patients,HOMA-IR may participate in them.
目的观察维持性血液透析患者的空腹血糖、血清胰岛素和血脂水平，计算胰岛素抵抗指数(HOMA-IR)和胰岛素敏感性指数(ISI)，评价其与胰岛素抵抗(IR)的关系，并与30项健康检查的相应指标进行相关性分析。方法选取维持性血液透析患者48例(观察组)和健康志愿者30例(对照组)作为研究对象。测定空腹血糖(FPG)、糖化血红蛋白(HbA1c)、空腹胰岛素(FIns)、尿素氮(BUN)、肌酐(Cr)、尿酸(UA)、血脂等指标，并分析它们之间的关系。结果患者BUN、Cr、UA、FIns、HbA1c、FPG、HOMA-IR均显著高于对照组，但对照组总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)显著低于对照组，BUN(24.9±5.8)mmol/L vs(5.0±1.6)mmol/L(P0.05)，Cr(820±222)μmol/L vs(73±17)μmol/L(P0.05)，UA(397±96)μmol/L vs(298±79)μmol/L(P0.05)，FIns(16±11)μmol/L vs(11±5)μmol/L(P0.05)，FPG(6.1±1.6)mmol/L vs(5.1±0.6)mmol/L(P0.05)， HOMA-IR 4.3±3.2 vs2.4±1.2 (P0.05); TC(4.2±1.2)更易/ L和(5.3±1.1)更易/ L (P0.05),高密度脂蛋白胆固醇(1.3±0.5)更易/ L和(1.6±0.4)更易/ L (P0.01);低密度(3.0±1.0)更易/ L和(4.1±1.1)更易/ L (P0.05)。TC与FPG呈负相关(r=-0.3482,P0.05)。HDL-C与FIns呈负相关(r=-0.2603,P0.05)。LDL-C与FPG呈负相关(r=-0.3289,P0.05)，甘油三酯与FPG、HOMA-IR呈正相关(r=0.371,0.368,P0.05)。结论维持性血液透析患者存在脂质代谢紊乱，HOMA-IR可能参与其中。
{"title":"The variation of lipid in maintenance hemodialysis and the relationship with insulin resistance","authors":"Li-li Wang, Xiaoliang Pang, Li-Hua Wang, Dong Wang","doi":"10.3760/CMA.J.ISSN.1673-4238.2010.003.006","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1673-4238.2010.003.006","url":null,"abstract":"Objective To observe the fasting glucose,serum insulin and lipid level in maintenance hemodialysis,calculate the insulin resistance index(HOMA-IR) and the insulin sensitivity index(ISI) to evaluate the relationship with insulin resistance(IR),to carry out correlation analysis with the corresponding index of 30 health examinations.Methods Forty-eight maintenance hemodialysis patients(observation group) and 30 healthy volunteers(control group) were included in this study.Fasting plasma glucose(FPG),glycosylated hemoglobin(HbA1c),fasting insulin(FIns),blood urea nitrogen(BUN),creatinine(Cr),uric acid(UA) and lipid indexes were measured,and the relationship of them analyzed.Results BUN,Cr,UA,FIns,HbA1c,FPG and HOMA-IR were significantly higher in patients than in controls,but total cholesterol(TC),high density lipid protein cholesterol(HDL-C) and low density lipid protein cholesterol(LDL-C) were significantly lower in controls,BUN(24.9±5.8) mmol/L vs(5.0±1.6) mmol/L(P0.05);Cr(820±222) μmol/L vs(73± 17) μmol/L(P0.05);UA(397±96) μmol/L vs(298±79) μmol/L(P0.05);FIns(16±11) mU/L vs(11± 5) mU/L(P0.05);FPG(6.1±1.6) mmol/L vs(5.1±0.6) mmol/L(P0.05);HOMA-IR 4.3±3.2 vs 2.4±1.2(P0.05);TC(4.2±1.2) mmol/L vs(5.3±1.1) mmol/L(P0.05);HDL-C(1.3±0.5) mmol/L vs(1.6±0.4) mmol/L(P0.01);LDL-C(3.0±1.0) mmol/L vs(4.1±1.1) mmol/L(P0.05).TC was negative correlated with FPG(r=-0.3482,P0.05).HDL-C was negative correlated with FIns(r=-0.2603,P0.05).LDL-C was negative correlated with FPG(r=-0.3289,P0.05),triglyceride was positively correlated with FPG and HOMA-IR(r=0.371,0.368,P0.05).Conclusion Lipid metabolic disorder existed in maintenance hemodialysis patients,HOMA-IR may participate in them.","PeriodicalId":10383,"journal":{"name":"Clinical Focus","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69910038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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