Jiwon Kim, Sunghwan Kim, Y. Um, Sheng-Min Wang, Regina E. Y. Kim, Yeong Sim Choe, Jiyeon Lee, Donghyeon Kim, H. Lim, Chang-Uk Lee, D. Kang
{"title":"Associations between Education Years and Resting-state Functional Connectivity Modulated by APOE ε4 Carrier Status in Cognitively Normal Older Adults","authors":"Jiwon Kim, Sunghwan Kim, Y. Um, Sheng-Min Wang, Regina E. Y. Kim, Yeong Sim Choe, Jiyeon Lee, Donghyeon Kim, H. Lim, Chang-Uk Lee, D. Kang","doi":"10.9758/cpn.23.1113","DOIUrl":"https://doi.org/10.9758/cpn.23.1113","url":null,"abstract":"","PeriodicalId":10420,"journal":{"name":"Clinical Psychopharmacology and Neuroscience","volume":"27 10","pages":""},"PeriodicalIF":3.2,"publicationDate":"2023-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139256421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Efficacy and Safety of Anti-CGRP Monoclonal Antibodies in Prevention of Chronic Migraine: A Bayesian Network Meta-analysis","authors":"Mundot Puliappadamb Haridas, Amruta Tripathy, Rituparna Maiti, Anand Srinivasan","doi":"10.9758/cpn.23.1109","DOIUrl":"https://doi.org/10.9758/cpn.23.1109","url":null,"abstract":"","PeriodicalId":10420,"journal":{"name":"Clinical Psychopharmacology and Neuroscience","volume":"105 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135346367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sung-Hoon Yoon, Jihye Oh, Yoo Hyun Um, Ho Jun Seo, Seung Chul Hong, Tae Won Kim, Jong-Hyun Jeong
{"title":"Differences in Electroencephalography Power and Asymmetry at Frontal Region in Young Adults with Attention-deficit/hyperactivity Disorder: A Quantitative Electroencephalography Study","authors":"Sung-Hoon Yoon, Jihye Oh, Yoo Hyun Um, Ho Jun Seo, Seung Chul Hong, Tae Won Kim, Jong-Hyun Jeong","doi":"10.9758/cpn.23.1104","DOIUrl":"https://doi.org/10.9758/cpn.23.1104","url":null,"abstract":"","PeriodicalId":10420,"journal":{"name":"Clinical Psychopharmacology and Neuroscience","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135635018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Psilocybin, an Effective Treatment for Major Depressive Disorder in Adults - A Systematic Review","authors":"Tessa Watford, Naqash Masood","doi":"10.9758/cpn.23.1120","DOIUrl":"https://doi.org/10.9758/cpn.23.1120","url":null,"abstract":"","PeriodicalId":10420,"journal":{"name":"Clinical Psychopharmacology and Neuroscience","volume":"235 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136078106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Comparative Investigation of Functional Connectivity Utilizing Electroencephalography in Insomnia Patients With and Without Restless Leg Syndrome","authors":"Seo-Young Park, Young-Min Park, Yang Rae Kim","doi":"10.9758/cpn.23.1117","DOIUrl":"https://doi.org/10.9758/cpn.23.1117","url":null,"abstract":"","PeriodicalId":10420,"journal":{"name":"Clinical Psychopharmacology and Neuroscience","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136077780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kanji Ueno, Makoto Ishitobi, Hirotaka Kosaka, Kei Ichijo, Yukihiro Nagase
{"title":"Mirtazapine Monotherapy for Antipsychotics-refractory Psychosis in a Patient with Very-late-onset Schizophrenia-like Psychosis: A Case Report","authors":"Kanji Ueno, Makoto Ishitobi, Hirotaka Kosaka, Kei Ichijo, Yukihiro Nagase","doi":"10.9758/cpn.23.1103","DOIUrl":"https://doi.org/10.9758/cpn.23.1103","url":null,"abstract":"","PeriodicalId":10420,"journal":{"name":"Clinical Psychopharmacology and Neuroscience","volume":"93 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135817359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shyh-Yuh Wei, Tsung-Han Tsai, Tsung-Yu Tsai, Po See Chen, Huai-Hsuan Tseng, Yen Kuang Yang, Tianye Zhai, Yihong Yang, Tzu-Yun Wang
Shyh-Yuh Wei, Tsung-Han Tsai, Tsung-Yu Tsai, Po See Chen, Huai-Hsuan Tseng, Yen Kuang Yang, Tianye Zhai, Yihong Yang, Tzu-Yun Wang. Clin Psychopharmacol Neurosci -0001;0:. https://doi.org/10.9758/cpn.23.1079
Shyh-Yuh Wei, Tsung-Han Tsai, Tsung-Yu Tsai, Po See Chen, Huai-Hsuan Tseng, Yen Kuang Yang, Tianye Zhai, Yihong Yang, Tzu-Yun Wang.Clin Psychopharmacol Neurosci -0001;0:. https://doi.org/10.9758/cpn.23.1079
{"title":"The Association between Default-mode Network Functional Connectivity and Childhood Trauma on the Symptom Load in Male Adults with Methamphetamine Use Disorder","authors":"Shyh-Yuh Wei, Tsung-Han Tsai, Tsung-Yu Tsai, Po See Chen, Huai-Hsuan Tseng, Yen Kuang Yang, Tianye Zhai, Yihong Yang, Tzu-Yun Wang","doi":"10.9758/cpn.23.1079","DOIUrl":"https://doi.org/10.9758/cpn.23.1079","url":null,"abstract":"Shyh-Yuh Wei, Tsung-Han Tsai, Tsung-Yu Tsai, Po See Chen, Huai-Hsuan Tseng, Yen Kuang Yang, Tianye Zhai, Yihong Yang, Tzu-Yun Wang. Clin Psychopharmacol Neurosci -0001;0:. https://doi.org/10.9758/cpn.23.1079","PeriodicalId":10420,"journal":{"name":"Clinical Psychopharmacology and Neuroscience","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134911902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Transcranial Electrical Stimulation: Clinical Implication and Practice for Treatment of Psychiatric Illness","authors":"Chaeyeon Yang, Bori Jung, Seung-Hwan Lee","doi":"10.9758/cpn.23.1118","DOIUrl":"https://doi.org/10.9758/cpn.23.1118","url":null,"abstract":"","PeriodicalId":10420,"journal":{"name":"Clinical Psychopharmacology and Neuroscience","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135981964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yong-Wook Kim, Sungkean Kim, Min Jin Jin, Chang-Hwan Im, Seung-Hwan Lee
{"title":"The Importance of Low-frequency Alpha (8−10 Hz) Waves and Default Mode Network in Behavioral Inhibition","authors":"Yong-Wook Kim, Sungkean Kim, Min Jin Jin, Chang-Hwan Im, Seung-Hwan Lee","doi":"10.9758/cpn.22.1035","DOIUrl":"https://doi.org/10.9758/cpn.22.1035","url":null,"abstract":"","PeriodicalId":10420,"journal":{"name":"Clinical Psychopharmacology and Neuroscience","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135691890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-31DOI: 10.9758/cpn.2022.20.2.240
Faruk Kurhan, H. Alp, M. Işık, Yavuz Selim Atan
Objective In this study, we aimed to examine thiol/disulfide homeostasis and oxidative DNA damage in patients with OCD and compare them with healthy controls. Methods Thirty-five patients previously diagnosed with OCD in Van Yuzuncu Yil University Department of Psychiatry and thirty-three healthy volunteers were included in the study. The severity of the symptoms was measured using the Yale-Brown Obsessive-Compulsive Scale. Five μL of blood samples were taken from the patient and control groups. The samples were stored at appropriate conditions until use. Leukocyte DNA was isolated and the levels of 8-hydroxy-2-deoxyguanosine (8-OHdG) and deoxyguanosine were detected to assess the oxidative DNA damage. The level of oxidative DNA damage was expressed as 8-OHdG/106dG. Total thiol/native thiol levels were measured for thiol/disulfide homeostasis. The level of disulfide was determined by subtracting the native thiol value from the total thiol value and the result was divided by two. Results were given as percentages. Results The total and native thiol levels in patients with OCD were significantly lower, and the disulfide levels were significantly higher in patients with OCD than healthy control subjects. In addition, 8-OHdG, an indicator of DNA damage, was significantly lower in the control group compared to the patient group. Conclusion Increased levels of disulfide/native thiol and disulfide/total thiol in patients with OCD show that levels of oxidative stress were elevated and therefore, higher 8-OHdG levels in patients with OCD is a marker of oxidative DNA damage.
{"title":"The Evaluation of Thiol/Disulfide Homeostasis and Oxidative DNA Damage in Patients with Obsessive Compulsive Disorder","authors":"Faruk Kurhan, H. Alp, M. Işık, Yavuz Selim Atan","doi":"10.9758/cpn.2022.20.2.240","DOIUrl":"https://doi.org/10.9758/cpn.2022.20.2.240","url":null,"abstract":"Objective In this study, we aimed to examine thiol/disulfide homeostasis and oxidative DNA damage in patients with OCD and compare them with healthy controls. Methods Thirty-five patients previously diagnosed with OCD in Van Yuzuncu Yil University Department of Psychiatry and thirty-three healthy volunteers were included in the study. The severity of the symptoms was measured using the Yale-Brown Obsessive-Compulsive Scale. Five μL of blood samples were taken from the patient and control groups. The samples were stored at appropriate conditions until use. Leukocyte DNA was isolated and the levels of 8-hydroxy-2-deoxyguanosine (8-OHdG) and deoxyguanosine were detected to assess the oxidative DNA damage. The level of oxidative DNA damage was expressed as 8-OHdG/106dG. Total thiol/native thiol levels were measured for thiol/disulfide homeostasis. The level of disulfide was determined by subtracting the native thiol value from the total thiol value and the result was divided by two. Results were given as percentages. Results The total and native thiol levels in patients with OCD were significantly lower, and the disulfide levels were significantly higher in patients with OCD than healthy control subjects. In addition, 8-OHdG, an indicator of DNA damage, was significantly lower in the control group compared to the patient group. Conclusion Increased levels of disulfide/native thiol and disulfide/total thiol in patients with OCD show that levels of oxidative stress were elevated and therefore, higher 8-OHdG levels in patients with OCD is a marker of oxidative DNA damage.","PeriodicalId":10420,"journal":{"name":"Clinical Psychopharmacology and Neuroscience","volume":"20 1","pages":"240 - 247"},"PeriodicalIF":3.2,"publicationDate":"2022-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46205731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}