The editors reflect on the effect of Social Determinants of Health in Clinical Decision Science on questions of efficacy and effectiveness.
编辑反映了临床决策科学中健康的社会决定因素对疗效和有效性问题的影响。
{"title":"From The Editor: Understanding how Social Determinants of Health are integrated within Clinical Decision Science","authors":"J. Meza, Nicholus H Yee","doi":"10.22237/crp/1665964860","DOIUrl":"https://doi.org/10.22237/crp/1665964860","url":null,"abstract":"The editors reflect on the effect of Social Determinants of Health in Clinical Decision Science on questions of efficacy and effectiveness.","PeriodicalId":10422,"journal":{"name":"Clinical Research In Practice: The Journal of Team Hippocrates","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88280954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A brief essay on how the COVID pandemic has changed how we think about medicine and our patients.
一篇关于COVID大流行如何改变我们对医学和患者的看法的简短文章。
{"title":"Reflection on Clinical Decision Science: The decision I never thought I would have to make","authors":"M. Nixon","doi":"10.22237/crp/1665964800","DOIUrl":"https://doi.org/10.22237/crp/1665964800","url":null,"abstract":"A brief essay on how the COVID pandemic has changed how we think about medicine and our patients.","PeriodicalId":10422,"journal":{"name":"Clinical Research In Practice: The Journal of Team Hippocrates","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78130040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A clinical decision report using: Kunkler IH, Williams LJ, Jack WJ, Cameron DA, Dixon JM; PRIME II investigators. Breast-conserving surgery with or without irradiation in women aged 65 years or older with early breast cancer (PRIME II): a randomised controlled trial [published correction appears in Lancet Oncol. 2015 Mar;16(3):e105]. Lancet Oncol. 2015;16(3):266-273. https://doi.org/10.1016/S1470-2045(14)71221-5 for an older patient seeking treatment for Stage 1 Ductal Breast Carcinoma.
临床决策报告使用:Kunkler IH, Williams LJ, Jack WJ, Cameron DA, Dixon JM;PRIME II调查人员。65岁及以上早期乳腺癌妇女保乳手术加或不加放疗(PRIME II):一项随机对照试验[发表更正见Lancet Oncol. 2015 Mar;16(3):e105]。中华医学杂志，2015;16(3):266-273。https://doi.org/10.1016/S1470-2045(14)71221-5for一位寻求1期导管性乳腺癌治疗的老年患者。
{"title":"Radiation therapy for older women with early breast cancer: An unnecessary hardship","authors":"L. Shawver","doi":"10.22237/crp/1656633720","DOIUrl":"https://doi.org/10.22237/crp/1656633720","url":null,"abstract":"A clinical decision report using:\u0000Kunkler IH, Williams LJ, Jack WJ, Cameron DA, Dixon JM; PRIME II investigators. Breast-conserving surgery with or without irradiation in women aged 65 years or older with early breast cancer (PRIME II): a randomised controlled trial [published correction appears in Lancet Oncol. 2015 Mar;16(3):e105]. Lancet Oncol. 2015;16(3):266-273. https://doi.org/10.1016/S1470-2045(14)71221-5\u0000for an older patient seeking treatment for Stage 1 Ductal Breast Carcinoma.","PeriodicalId":10422,"journal":{"name":"Clinical Research In Practice: The Journal of Team Hippocrates","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82206734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A clinical decision report using: McElroy SL, Hudson J, Ferreira-Cornwell MC, Radewonuk J, Whitaker T, Gasior M. Lisdexamfetamine dimesylate for adults with moderate to severe binge eating disorder: Results of two pivotal phase 3 randomized controlled trials. Neuropsychopharmacology. 2016;41(5):1251-1260. https://doi.org/10.1038/npp.2015.275 for a young woman requesting a novel pharmacological intervention for a Binge Eating Disorder (BED).
{"title":"Lisdexamfetamine is an effective monotherapy for moderate to severe binge eating disorder","authors":"Benjamin Young","doi":"10.22237/crp/1656633660","DOIUrl":"https://doi.org/10.22237/crp/1656633660","url":null,"abstract":"A clinical decision report using:\u0000McElroy SL, Hudson J, Ferreira-Cornwell MC, Radewonuk J, Whitaker T, Gasior M. Lisdexamfetamine dimesylate for adults with moderate to severe binge eating disorder: Results of two pivotal phase 3 randomized controlled trials. Neuropsychopharmacology. 2016;41(5):1251-1260. https://doi.org/10.1038/npp.2015.275\u0000for a young woman requesting a novel pharmacological intervention for a Binge Eating Disorder (BED).","PeriodicalId":10422,"journal":{"name":"Clinical Research In Practice: The Journal of Team Hippocrates","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72753337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Francis, Mira Hamame, Mariam Nasrallah, Alison Nesbitt, J. Meza
An informed consent article using Hammond FM, Alexander DN, Cutler AJ, et al. PRISM II: an open-label study to assess effectiveness of dextromethorphan/quinidine for pseudobulbar affect in patients with dementia, stroke or traumatic brain injury. BMC Neurology. 2016;16:89. https://doi.org/10.1186/s12883-016-0609-0 for a patient with pseudobulbar affect following stroke.
一篇使用hammond FM, Alexander DN, Cutler AJ等人的知情同意文章。PRISM II:一项开放标签研究，旨在评估右美沙芬/奎尼丁治疗痴呆、中风或创伤性脑损伤患者假性球影响的有效性。中华医学会神经病学杂志。2016;16:89。https://doi.org/10.1186/s12883-016-0609-0for中风后假性球影响患者。
{"title":"Dextromethorphan-quinidine is helpful for pseudobulbar affect disorder in stroke patients","authors":"M. Francis, Mira Hamame, Mariam Nasrallah, Alison Nesbitt, J. Meza","doi":"10.22237/crp/1636070400","DOIUrl":"https://doi.org/10.22237/crp/1636070400","url":null,"abstract":"An informed consent article using\u0000Hammond FM, Alexander DN, Cutler AJ, et al. PRISM II: an open-label study to assess effectiveness of dextromethorphan/quinidine for pseudobulbar affect in patients with dementia, stroke or traumatic brain injury. BMC Neurology. 2016;16:89. https://doi.org/10.1186/s12883-016-0609-0\u0000for a patient with pseudobulbar affect following stroke.","PeriodicalId":10422,"journal":{"name":"Clinical Research In Practice: The Journal of Team Hippocrates","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85031130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A clinical decision report using: Andrade R, Rodriguez-Barradas MC, Yasukawa K, Villarreal E, Ross M, Serpa JA. Single Dose Versus 3 Doses of Intramuscular Benzathine Penicillin for Early Syphilis in HIV: A Randomized Clinical Trial. Clin Infect Dis. 2017;64(6):759-764. https://doi.org/10.1093/cid/ciw862 to inform treatment of syphilis for a person living with HIV with multiple socioeconomic barriers to care.
临床决策报告使用:Andrade R, Rodriguez-Barradas MC, yasawa K, Villarreal E, Ross M, Serpa JA。单剂量与3剂量肌注苄星青霉素治疗HIV早期梅毒:一项随机临床试验。临床感染杂志，2017;64(6):759-764。https://doi.org/10.1093/cid/ciw862为有多重社会经济障碍的艾滋病毒感染者提供梅毒治疗信息。
{"title":"How much penicillin is needed to treat early syphilis in people living with HIV?","authors":"L. Bonadonna","doi":"10.22237/crp/1625098020","DOIUrl":"https://doi.org/10.22237/crp/1625098020","url":null,"abstract":"A clinical decision report using:\u0000 Andrade R, Rodriguez-Barradas MC, Yasukawa K, Villarreal E, Ross M, Serpa JA. Single Dose Versus 3 Doses of Intramuscular Benzathine Penicillin for Early Syphilis in HIV: A Randomized Clinical Trial. Clin Infect Dis. 2017;64(6):759-764. https://doi.org/10.1093/cid/ciw862\u0000 to inform treatment of syphilis for a person living with HIV with multiple socioeconomic barriers to care.","PeriodicalId":10422,"journal":{"name":"Clinical Research In Practice: The Journal of Team Hippocrates","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79181519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A clinical decision report using Jung HY, Jeon Y, Park Y, et al. Better Quality of Life of Peritoneal Dialysis compared to Hemodialysis over a Two-year Period after Dialysis Initiation. Sci Rep. Jul 16 2019;9(1):10266. https://doi.org/10.1038/s41598-019-46744-1 for a young patient initiating dialysis.
Jung HY, Jeon Y, Park Y等的临床决策报告。腹膜透析与血液透析相比，在透析开始后的两年内生活质量更好。科学通报，2019;9(1):1066。https://doi.org/10.1038/s41598-019-46744-1对于一个开始透析的年轻病人。
{"title":"Peritoneal dialysis vs. hemodialysis: The choice of modality of dialysis may drastically affect the quality of life of patients initiating dialysis","authors":"Deepak Daryani","doi":"10.22237/crp/1625097840","DOIUrl":"https://doi.org/10.22237/crp/1625097840","url":null,"abstract":"A clinical decision report using\u0000 Jung HY, Jeon Y, Park Y, et al. Better Quality of Life of Peritoneal Dialysis compared to Hemodialysis over a Two-year Period after Dialysis Initiation. Sci Rep. Jul 16 2019;9(1):10266. https://doi.org/10.1038/s41598-019-46744-1\u0000 for a young patient initiating dialysis.","PeriodicalId":10422,"journal":{"name":"Clinical Research In Practice: The Journal of Team Hippocrates","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75358554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A clinical decision report using: Beigel JH, Tomashek KM, Dodd LE, et al. Remdesivir for the Treatment of Covid-19 — Final Report. N Engl J Med. 2020;383:1813-1826. https://doi.org/10.1056/NEJMoa2007764 for a patient with severe COVID-19.
临床决策报告使用:Beigel JH, Tomashek KM, Dodd LE等。瑞德西韦治疗Covid-19的最终报告。中华医学杂志，2010;33(3):326 - 326。对于患有严重COVID-19的患者https://doi.org/10.1056/NEJMoa2007764。
{"title":"Remdesivir has questionable efficacy in patients with severe COVID-19 receiving high-flow oxygen","authors":"Gabriel B. Burdick","doi":"10.22237/crp/1625097660","DOIUrl":"https://doi.org/10.22237/crp/1625097660","url":null,"abstract":"A clinical decision report using:\u0000 Beigel JH, Tomashek KM, Dodd LE, et al. Remdesivir for the Treatment of Covid-19 — Final Report. N Engl J Med. 2020;383:1813-1826. https://doi.org/10.1056/NEJMoa2007764\u0000 for a patient with severe COVID-19.","PeriodicalId":10422,"journal":{"name":"Clinical Research In Practice: The Journal of Team Hippocrates","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87865753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A clinical decision report using: Wright AA, Zhang B, Ray A, Mack JW, Trice E, Balboni T, Mitchell SL, Jackson VA, Block SD, Maciejewski PK, & Prigerson HG. Associations between end-of-life discussions, patient mental health, medical care near death, and caregiver bereavement adjustment. JAMA. 2008;300(14):1665-1673. https://doi.org/10.1001/jama.300.14.1665 for a patient with end stage cancer and an anxious caregiver.
临床决策报告使用:Wright AA, Zhang B, Ray A, Mack JW, Trice E, Balboni T, Mitchell SL, Jackson VA, Block SD, Maciejewski PK， & Prigerson HG。临终讨论、患者心理健康、临终前医疗护理和照顾者丧亲适应之间的关系。《美国医学协会杂志》上。2008; 300(14): 1665 - 1673。为癌症晚期患者和焦虑的护理者提供https://doi.org/10.1001/jama.300.14.1665。
{"title":"A light in the dark: end-of-life conversations in advanced cancer patients improve caregiver grief","authors":"Nicole Meeks","doi":"10.22237/crp/1622160900","DOIUrl":"https://doi.org/10.22237/crp/1622160900","url":null,"abstract":"A clinical decision report using:\u0000 Wright AA, Zhang B, Ray A, Mack JW, Trice E, Balboni T, Mitchell SL, Jackson VA, Block SD, Maciejewski PK, & Prigerson HG. Associations between end-of-life discussions, patient mental health, medical care near death, and caregiver bereavement adjustment. JAMA. 2008;300(14):1665-1673. https://doi.org/10.1001/jama.300.14.1665\u0000 for a patient with end stage cancer and an anxious caregiver.","PeriodicalId":10422,"journal":{"name":"Clinical Research In Practice: The Journal of Team Hippocrates","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88868465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A clinical decision report using: Orkin C, Molina JM, Negredo E, et al. Efficacy and safety of switching from boosted protease inhibitors plus emtricitabine and tenofovir disoproxil fumarate regimens to single-tablet darunavir, cobicistat, emtricitabine, and tenofovir alafenamide at 48 weeks in adults with virologically suppressed HIV-1 (EMERALD): a phase 3, randomised, non-inferiority trial. Lancet HIV. 2018;5(1):e23-e34. https://doi.org/10.1016/S2352-3018(17)30179-0 for a patient with viriologically suppressed HIV-1.
{"title":"Using a single tablet regimen of darunavir, cobicistat, emcitrabine, and tenofovir alafenamide in virally suppressed HIV-1 patients is an adequate treatment option for controlling HIV","authors":"Priya Kathuria","doi":"10.22237/crp/1625097720","DOIUrl":"https://doi.org/10.22237/crp/1625097720","url":null,"abstract":"A clinical decision report using:\u0000 Orkin C, Molina JM, Negredo E, et al. Efficacy and safety of switching from boosted protease inhibitors plus emtricitabine and tenofovir disoproxil fumarate regimens to single-tablet darunavir, cobicistat, emtricitabine, and tenofovir alafenamide at 48 weeks in adults with virologically suppressed HIV-1 (EMERALD): a phase 3, randomised, non-inferiority trial. Lancet HIV. 2018;5(1):e23-e34. https://doi.org/10.1016/S2352-3018(17)30179-0\u0000 for a patient with viriologically suppressed HIV-1.","PeriodicalId":10422,"journal":{"name":"Clinical Research In Practice: The Journal of Team Hippocrates","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78618644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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