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Response to: Letter to the editor: Sleep measures and cardiovascular disease in type 2 diabetes mellitus. 回应致编辑的信:2型糖尿病患者的睡眠质量与心血管疾病。
IF 4.4 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-01-01 Epub Date: 2024-02-07 DOI: 10.1016/j.clinme.2024.100023
Caroline J Magri, Sara Xuereb, Rachel-Anne Xuereb, Robert G Xuereb, Stephen Fava, Joseph Galea
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引用次数: 0
Chronic pulmonary aspergillosis - a guide for the general physician. 慢性肺曲霉菌病--全科医生指南》。
IF 4.4 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-01-01 Epub Date: 2024-01-26 DOI: 10.1016/j.clinme.2024.100019
Charlotte Carter, Rasleen Kahai, Josie Cunningham, Jennifer Kilduff, Natasha Hough, Caroline Baxter, David Connell, Anand Shah

This collaborative article presents a review of chronic pulmonary aspergillosis (CPA) from the perspective of a multidisciplinary team comprising of respiratory physicians, radiologists, mycologists, dietitians, pharmacists, physiotherapists and palliative care specialists. The review synthesises current knowledge on CPA, emphasising the intricate interplay between clinical, radiological, and microbiological aspects. We highlight the importance of assessing each patient as multidisciplinary team to ensure personalised treatment strategies and a holistic approach to patient care.

这篇合作文章从由呼吸科医生、放射科医生、真菌学家、营养师、药剂师、物理治疗师和姑息治疗专家组成的多学科团队的角度,对慢性肺曲霉菌病(CPA)进行了综述。这篇综述综述了当前有关 CPA 的知识,强调了临床、放射学和微生物学等方面错综复杂的相互作用。我们强调了多学科团队对每位患者进行评估的重要性,以确保个性化的治疗策略和整体的患者护理方法。
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引用次数: 0
Letter to the editor: Are we missing pancreatic exocrine insufficiency in 'at-risk' groups? 致编辑的信:我们是否遗漏了 "高危 "人群中的胰腺外分泌功能不全?
IF 4.4 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-01-01 Epub Date: 2024-01-28 DOI: 10.1016/j.clinme.2024.100022
Moses Silungwe Kapembwa, Simon Charles Fleming, Philip Anthony Batman, George Edward Griffin
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引用次数: 0
The UK research ethics committee: Making the case for better serving the underserved - can we do better? 英国研究伦理委员会:为更好地服务于得不到充分服务的人群创造条件--我们能做得更好吗?
IF 4.4 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-01-01 Epub Date: 2024-02-12 DOI: 10.1016/j.clinme.2023.100012
Matthew Parsons, James Ratcliff, Bernadette Egan, Hana Hassanin, Aftab Ala

Research ethics committees exist internationally to review research proposals to protect the rights and safety of human participants and researchers involved in research. These committees recruit a panel of expert and lay members, mostly on an unpaid voluntary basis, with relevant scientific experience to appraise these studies. Contemporary data in the UK show that women and people over 55 years old are overrepresented in these committee panels in the Health Research Authority, suggesting that there are potential barriers to inclusivity and participation. A variety of global approaches to tackle these barriers include targeting specific populations, such as faith or community leaders, or implementing quotas have been adopted. Further research is needed to understand likely barriers preventing participation in research ethics committees in the UK and how they may be overcome.

国际上设有研究伦理委员会,负责审查研究提案,以保护参与研究的人类参与者和研究人员的权利和安全。这些委员会招募由专家和非专业人员组成的小组对这些研究进行评估,这些成员大多是无偿志愿加入的,并具有相关的科学经验。英国的当代数据显示,在卫生研究局的这些委员会小组中,女性和 55 岁以上的人所占比例过高,这表明在包容性和参与性方面存在潜在障碍。为解决这些障碍,全球采取了多种方法,包括针对特定人群(如宗教或社区领袖)或实施配额制。要了解阻碍英国研究伦理委员会参与的可能障碍以及如何克服这些障碍,还需要进一步的研究。
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引用次数: 0
Evidence-based appraisal of situational judgement tests (revisited). 致编辑的信:基于证据的情境判断测试评估(重温)。
IF 4.4 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-01-01 Epub Date: 2024-01-28 DOI: 10.1016/j.clinme.2024.100020
Gurvinder Sahota, John McLachlan, Fiona Patterson, Paul Tiffin
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引用次数: 0
A complex case of dysphagia with dual aetiology. 一个具有双重病因的复杂吞咽困难病例。
IF 4.4 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-01-01 Epub Date: 2024-02-14 DOI: 10.1016/j.clinme.2023.100010
Catherine Sykes, Matthew Banks, Humayra Dervin, Andres Vales, Rami Sweis

A woman in her early 60s was referred with dysphagia and chest pain to a tertiary referral centre specialising in oesophageal disorders. Cardiac symptom origin and sinister oesophageal pathology had been excluded at her local hospital in NHS Scotland. Under multidisciplinary team oversight, reinvestigation of mucosal pathology and oesophageal motility ultimately uncovered both Type III achalasia and eosinophilic oesophagitis. This case demonstrates the benefit of including provocative testing during high-resolution manometry to reproduce relevant dysphagia and the importance of stopping proton-pump inhibitors long enough to uncover excessive eosinophils which could otherwise be masked. Ultimately, tailored management for both conditions separately was required to achieve symptoms resolution.

一名 60 多岁的妇女因吞咽困难和胸痛被转诊到一家专门治疗食道疾病的三级转诊中心。她在苏格兰国家医疗服务体系的当地医院排除了心脏症状和食道病变的可能性。在多学科团队的监督下,对粘膜病理和食管运动的重新调查最终发现了 III 型贲门失弛缓症和嗜酸性粒细胞性食管炎。该病例表明,在高分辨率测压过程中进行挑衅性测试以重现相关吞咽困难是有好处的,而且停用质子泵抑制剂足够长的时间以发现过多的嗜酸性粒细胞也很重要,否则可能会被掩盖。最终,需要对这两种情况分别进行量身定制的治疗,才能使症状得到缓解。
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引用次数: 0
Sleep measures and cardiovascular disease in type 2 diabetes mellitus. 致编辑的信:2型糖尿病患者的睡眠质量与心血管疾病。
IF 4.4 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-01-01 Epub Date: 2024-01-28 DOI: 10.1016/j.clinme.2024.100021
M Engin
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引用次数: 0
Patients with cancer and sepsis trials: an unfair representation? 癌症患者与败血症试验:不公平的代表性?
IF 4.4 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-12-08 DOI: 10.7861/clinmed.2023-0408
Elizabeth Nelmes, Luke Edwards, Shaman Jhanji, David B Antcliffe, Kate C Tatham

Approximately 20% of sepsis cases are thought to occur in patients with cancer. Thus, such patients are an important cohort to be represented and characterised among sepsis trials. However, patients with cancer are commonly excluded from sepsis trials, although the extent to which is unknown. In this opinion article, we discuss our findings that suggest that patients with cancer are being under-represented in sepsis trials, often with an unclear rationale. We question the validity of generalising results from sepsis trials to heterogenous cancer populations and call for wider inclusion of patients with cancer to bridge this knowledge gap in sepsis management.

据认为,大约 20% 的败血症病例发生在癌症患者身上。因此,在败血症试验中,癌症患者是一个重要的群体。然而,癌症患者通常被排除在败血症试验之外,尽管其程度尚不清楚。在这篇观点文章中,我们讨论了我们的研究结果,这些结果表明癌症患者在败血症试验中的代表性不足,而且往往理由不明。我们质疑将脓毒症试验结果归纳到异质性癌症人群的有效性,并呼吁更广泛地纳入癌症患者,以弥补脓毒症管理方面的知识差距。
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引用次数: 0
Time to treat the climate and nature crisis as one indivisible global health emergency. 是时候将气候和自然危机视为一个不可分割的全球卫生紧急事件了。
IF 4.4 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-12-08 DOI: 10.7861/clinmed.ed.23.6.2
Kamran Abbasi, Parveen Ali, Virginia Barbour, Thomas Benfield, Kirsten Bibbins-Domingo, Stephen Hancocks, Richard Horton, Laurie Laybourn-Langton, Robert Mash, Peush Sahni, Wadeia Mohammad Sharief, Paul Yonga, Chris Zielinski
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引用次数: 0
Research activity among physicians in the United Kingdom: results from the Royal College of Physicians Census 2022. 英国医生的研究活动:英国皇家内科学院 2022 年普查结果。
IF 4.4 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-12-08 DOI: 10.7861/clinmed.2023-0388
Subashini Chandrapalan, Chris Phillips, Nina Newbery, Sarah Logan, Ramesh Arasaradnam

We present the results of the 2022 Census of the Federation of Royal Colleges of Physicians of Edinburgh, Glasgow and London on whether physicians undertake research and the barriers they have encountered. 40% of physicians reported that they undertook research alongside their clinical work. Multivariate analysis of the responses showed that men were 1.6 times more likely to say they undertake research than women. The main barriers to undertaking research were having enough time, organisational factors and a lack of confidence. In this opinion piece we discuss some of the challenges and how they could be addressed.

我们介绍了爱丁堡、格拉斯哥和伦敦皇家医学院联合会 2022 年的普查结果,内容涉及医生是否从事研究以及他们遇到的障碍。40%的医生表示,他们在从事临床工作的同时还进行研究。对回答进行的多变量分析表明,男性说自己从事研究的可能性是女性的 1.6 倍。开展研究的主要障碍是没有足够的时间、组织因素和缺乏自信。在这篇观点文章中,我们将讨论其中的一些挑战以及如何应对这些挑战。
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引用次数: 0
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Clinical Medicine
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