Pub Date : 2021-12-04DOI: 10.1007/978-3-030-51519-5_51-1
A. Talevi, C. Bellera
{"title":"Free Drug Theory","authors":"A. Talevi, C. Bellera","doi":"10.1007/978-3-030-51519-5_51-1","DOIUrl":"https://doi.org/10.1007/978-3-030-51519-5_51-1","url":null,"abstract":"","PeriodicalId":105001,"journal":{"name":"The ADME Encyclopedia","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120959657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The fraction of the treatment dose reaches the systemic circulation; is the ratio of the amount of drug in the system after administration of a test formulation divided by the drug in the system after IV administration.
治疗剂量到达体循环的部分;是给药后系统中的药物量与静脉给药后系统中的药物量之比。
{"title":"Absolute Bioavailability","authors":"P. Quiroga","doi":"10.32388/dt4eb9","DOIUrl":"https://doi.org/10.32388/dt4eb9","url":null,"abstract":"The fraction of the treatment dose reaches the systemic circulation; is the ratio of the amount of drug in the system after administration of a test formulation divided by the drug in the system after IV administration.","PeriodicalId":105001,"journal":{"name":"The ADME Encyclopedia","volume":"77 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133315073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.1007/978-3-030-51519-5_66-1
A. Talevi, C. Bellera
{"title":"Phase 0 and Phase III Transport","authors":"A. Talevi, C. Bellera","doi":"10.1007/978-3-030-51519-5_66-1","DOIUrl":"https://doi.org/10.1007/978-3-030-51519-5_66-1","url":null,"abstract":"","PeriodicalId":105001,"journal":{"name":"The ADME Encyclopedia","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125080881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.1007/978-3-030-51519-5_77-1
Liam M. Koehn
{"title":"ABC Transporters: Drug Transfer Across Cellular Interfaces","authors":"Liam M. Koehn","doi":"10.1007/978-3-030-51519-5_77-1","DOIUrl":"https://doi.org/10.1007/978-3-030-51519-5_77-1","url":null,"abstract":"","PeriodicalId":105001,"journal":{"name":"The ADME Encyclopedia","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126831284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.1007/978-3-030-51519-5_161-1
M. Vázquez, R. Eiraldi, C. Maldonado
{"title":"Rhythms in Pharmacokinetics: Absorption and Disposition","authors":"M. Vázquez, R. Eiraldi, C. Maldonado","doi":"10.1007/978-3-030-51519-5_161-1","DOIUrl":"https://doi.org/10.1007/978-3-030-51519-5_161-1","url":null,"abstract":"","PeriodicalId":105001,"journal":{"name":"The ADME Encyclopedia","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129087242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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