Purpose. Ovarian cancer in the early stage requires a complete surgical staging, including radical lymphadenectomy, implying subsequent risk of morbidity and complications. Sentinel lymph node (SLN) mapping is a procedure that attempts to reduce radical lymphadenectomy-related complications and morbidities. Our study evaluates the feasibility of SLN mapping in patients with ovarian tumors by the use of intraoperative Technetium-99m-Phytate (Tc-99m-Phytate) and postoperative lymphoscintigraphy using tomographic (single-photon emission computed tomography/computed tomography (SPECT/CT)) acquisition. Materials and Methods. Thirty-two patients with ovarian mass participated in this study. Intraoperative injection of the radiopharmaceutical was performed just after laparotomy and before the removal of tumor in utero-ovarian and suspensory ligaments of the ovary just beneath the peritoneum. Subsequently, pelvic and para-aortic lymphadenectomy was performed for malignant masses, and the presence of tumor in the lymph nodes was assessed through histopathological examination. Conversely, lymphadenectomy was not performed in patients with benign lesions or borderline ovarian tumors. Lymphoscintigraphy was performed within 24 hr using tomographic acquisition (SPECT/CT) of the abdomen and pelvis. Results. Final pathological examination showed 19 patients with benign pathology, 5 with borderline tumors, and 6 with malignant ovarian tumors. SPECT/CT identified SLNs in para-aortic-only areas in 6 (20%), pelvic/para-aortic areas in 14 (47%), and pelvic-only areas in 7 (23%) cases. Notably, additional unusual SLN locations were revealed in perirenal, intergluteal, and posterior to psoas muscle regions in three patients. We were not able to calculate the false negative rate due to the absence of patients with involved lymph nodes. Conclusion. SLN mapping using intraoperative injection of radiotracers is safe and feasible. Larger studies with more malignant cases are needed to better evaluate the sensitivity of this method for lymphatic staging of ovarian malignancies.
{"title":"Sentinel Node Mapping in Ovarian Tumors: A Study Using Lymphoscintigraphy and SPECT/CT","authors":"Saeideh Ataei Nakhaei, Ramin Sadeghi, Sayyed Mostafa Mostafavi, Giorgio Treglia, Malihe Hassanzadeh, Maryam Esmaeilpour, Negar Sadat Taheri, Marjaneh Farazestanian","doi":"10.1155/2024/5453692","DOIUrl":"10.1155/2024/5453692","url":null,"abstract":"<p><i>Purpose</i>. Ovarian cancer in the early stage requires a complete surgical staging, including radical lymphadenectomy, implying subsequent risk of morbidity and complications. Sentinel lymph node (SLN) mapping is a procedure that attempts to reduce radical lymphadenectomy-related complications and morbidities. Our study evaluates the feasibility of SLN mapping in patients with ovarian tumors by the use of intraoperative Technetium-99m-Phytate (Tc-99m-Phytate) and postoperative lymphoscintigraphy using tomographic (single-photon emission computed tomography/computed tomography (SPECT/CT)) acquisition. <i>Materials and Methods</i>. Thirty-two patients with ovarian mass participated in this study. Intraoperative injection of the radiopharmaceutical was performed just after laparotomy and before the removal of tumor in utero-ovarian and suspensory ligaments of the ovary just beneath the peritoneum. Subsequently, pelvic and para-aortic lymphadenectomy was performed for malignant masses, and the presence of tumor in the lymph nodes was assessed through histopathological examination. Conversely, lymphadenectomy was not performed in patients with benign lesions or borderline ovarian tumors. Lymphoscintigraphy was performed within 24 hr using tomographic acquisition (SPECT/CT) of the abdomen and pelvis. <i>Results</i>. Final pathological examination showed 19 patients with benign pathology, 5 with borderline tumors, and 6 with malignant ovarian tumors. SPECT/CT identified SLNs in para-aortic-only areas in 6 (20%), pelvic/para-aortic areas in 14 (47%), and pelvic-only areas in 7 (23%) cases. Notably, additional unusual SLN locations were revealed in perirenal, intergluteal, and posterior to psoas muscle regions in three patients. We were not able to calculate the false negative rate due to the absence of patients with involved lymph nodes. <i>Conclusion</i>. SLN mapping using intraoperative injection of radiotracers is safe and feasible. Larger studies with more malignant cases are needed to better evaluate the sensitivity of this method for lymphatic staging of ovarian malignancies.</p>","PeriodicalId":10656,"journal":{"name":"Contrast media & molecular imaging","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139949508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-13eCollection Date: 2023-01-01DOI: 10.1155/2023/9830349
Contrast Media Molecular Imaging
[This retracts the article DOI: 10.1155/2022/5238941.].
[本文撤回了文章 DOI：10.1155/2022/5238941]。
{"title":"Retracted: Characteristics Scanning of Brain Structure and Function Changes in Patients with Different Degrees of Alzheimer's Disease.","authors":"Contrast Media Molecular Imaging","doi":"10.1155/2023/9830349","DOIUrl":"https://doi.org/10.1155/2023/9830349","url":null,"abstract":"<p><p>[This retracts the article DOI: 10.1155/2022/5238941.].</p>","PeriodicalId":10656,"journal":{"name":"Contrast media & molecular imaging","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10733008/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138828599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-13eCollection Date: 2023-01-01DOI: 10.1155/2023/9791810
Contrast Media Molecular Imaging
[This retracts the article DOI: 10.1155/2022/8521051.].
[本文撤回文章 DOI：10.1155/2022/8521051.]。
{"title":"Retracted: Effects of Stress on Osteoblast Proliferation and Differentiation Based on Endoplasmic Reticulum Stress and Wnt<i>β</i>-Catenin Signaling Pathway.","authors":"Contrast Media Molecular Imaging","doi":"10.1155/2023/9791810","DOIUrl":"https://doi.org/10.1155/2023/9791810","url":null,"abstract":"<p><p>[This retracts the article DOI: 10.1155/2022/8521051.].</p>","PeriodicalId":10656,"journal":{"name":"Contrast media & molecular imaging","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10732788/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138828600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-13eCollection Date: 2023-01-01DOI: 10.1155/2023/9761084
Contrast Media Molecular Imaging
[This retracts the article DOI: 10.1155/2022/6128845.].
[本文撤消了文章 DOI：10.1155/2022/6128845]。
{"title":"Retracted: Analysis of the Performance of Gadoxetic Acid Disodium MRI in Predicting Microvascular Invasion of Hepatocellular Carcinoma.","authors":"Contrast Media Molecular Imaging","doi":"10.1155/2023/9761084","DOIUrl":"https://doi.org/10.1155/2023/9761084","url":null,"abstract":"<p><p>[This retracts the article DOI: 10.1155/2022/6128845.].</p>","PeriodicalId":10656,"journal":{"name":"Contrast media & molecular imaging","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10732902/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138828598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-29eCollection Date: 2023-01-01DOI: 10.1155/2023/9797605
Contrast Media Molecular Imaging
[This retracts the article DOI: 10.1155/2022/6716324.].
[此文撤稿，DOI: 10.1155/2022/6716324.]。
{"title":"Retracted: Bioinformatic Deconstruction of Differentially Expressed Sequence Tags in Hepatocellular Carcinoma Based on Artificial Neural Network.","authors":"Contrast Media Molecular Imaging","doi":"10.1155/2023/9797605","DOIUrl":"https://doi.org/10.1155/2023/9797605","url":null,"abstract":"<p><p>[This retracts the article DOI: 10.1155/2022/6716324.].</p>","PeriodicalId":10656,"journal":{"name":"Contrast media & molecular imaging","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10700921/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138798828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-29eCollection Date: 2023-01-01DOI: 10.1155/2023/9795808
Contrast Media Molecular Imaging
[This retracts the article DOI: 10.1155/2022/6120337.].
[本文撤回了文章 DOI：10.1155/2022/6120337]。
{"title":"Retracted: Clinical Value of PET.CT Based on Big Data in Colorectal and Peritoneal Metastatic Cancer.","authors":"Contrast Media Molecular Imaging","doi":"10.1155/2023/9795808","DOIUrl":"https://doi.org/10.1155/2023/9795808","url":null,"abstract":"<p><p>[This retracts the article DOI: 10.1155/2022/6120337.].</p>","PeriodicalId":10656,"journal":{"name":"Contrast media & molecular imaging","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10700775/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138798848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-29eCollection Date: 2023-01-01DOI: 10.1155/2023/9823903
Contrast Media Molecular Imaging
[This retracts the article DOI: 10.1155/2022/7146978.].
[本文撤回文章 DOI：10.1155/2022/7146978]。
{"title":"Retracted: Deconstruction of Clinical Treatment of Pneumonia and Respiratory Tract Infection Based on MRI Molecular Imaging.","authors":"Contrast Media Molecular Imaging","doi":"10.1155/2023/9823903","DOIUrl":"https://doi.org/10.1155/2023/9823903","url":null,"abstract":"<p><p>[This retracts the article DOI: 10.1155/2022/7146978.].</p>","PeriodicalId":10656,"journal":{"name":"Contrast media & molecular imaging","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10701028/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138798864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-29eCollection Date: 2023-01-01DOI: 10.1155/2023/9754521
Contrast Media Molecular Imaging
[This retracts the article DOI: 10.1155/2022/5820707.].
[本文撤回了文章 DOI：10.1155/2022/5820707]。
{"title":"Retracted: Analysis of Nursing Effect of Comprehensive Nursing Intervention on Hemodialysis Patients with Uremia.","authors":"Contrast Media Molecular Imaging","doi":"10.1155/2023/9754521","DOIUrl":"https://doi.org/10.1155/2023/9754521","url":null,"abstract":"<p><p>[This retracts the article DOI: 10.1155/2022/5820707.].</p>","PeriodicalId":10656,"journal":{"name":"Contrast media & molecular imaging","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10700895/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138798783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-29eCollection Date: 2023-01-01DOI: 10.1155/2023/9847843
Contrast Media Molecular Imaging
[This retracts the article DOI: 10.1155/2022/3176134.].
[本文撤回文章 DOI：10.1155/2022/3176134.]。
{"title":"Retracted: Automatic Detection and Classification of Epileptic Seizures in Patients with Liver Cirrhosis and Overlapping Hev Infection Based on Deep Multimodal Fusion Technology.","authors":"Contrast Media Molecular Imaging","doi":"10.1155/2023/9847843","DOIUrl":"https://doi.org/10.1155/2023/9847843","url":null,"abstract":"<p><p>[This retracts the article DOI: 10.1155/2022/3176134.].</p>","PeriodicalId":10656,"journal":{"name":"Contrast media & molecular imaging","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10700892/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138798788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-29eCollection Date: 2023-01-01DOI: 10.1155/2023/9793546
Contrast Media Molecular Imaging
[This retracts the article DOI: 10.1155/2022/5785025.].
[此文撤稿，DOI: 10.1155/2022/5785025.]。
{"title":"Retracted: Mechanism of Anti-Inflammatory Drugs in the Early Treatment of Oral Gingival Mucosa and Soft Tissue Trauma.","authors":"Contrast Media Molecular Imaging","doi":"10.1155/2023/9793546","DOIUrl":"https://doi.org/10.1155/2023/9793546","url":null,"abstract":"<p><p>[This retracts the article DOI: 10.1155/2022/5785025.].</p>","PeriodicalId":10656,"journal":{"name":"Contrast media & molecular imaging","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10701037/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138799113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
扫码关注我们
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号