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Criticism of psychiatric treatment 对精神病治疗的批评
Pub Date : 2019-05-01 DOI: 10.1093/MED/9780198807254.003.0007
A. Huda
Criticisms of psychiatric treatment often involve comparison to idealized depictions of general medical treatment. Psychiatric treatments are described as not reversing diseases but many treatments in general medicine also do not reverse disease and some have unknown mechanisms. It is stated that psychiatrists prescribe medication to reverse hypothesized mechanisms, but a survey found they usually prescribed a medication in a clinical situation because research had shown it to be effective, even though the mechanism of action was unclear. Antidepressants are said to be ineffective because of a small overall effect averaged over groups of participants but this ignores evidence that some people will derive a significant clinical benefit. Antipsychotics are effective in preventing relapse of psychosis in research studies; for a variety of reasons, withdrawal-induced psychosis is unlikely to explain enough of this advantage to prove the claim that antipsychotics are ineffective. Although lithium research trials are imperfect, including reporting high rates of lithium withdrawal-induced mania, there is still some evidence of benefit in acute mania and of modest benefit in preventing relapse of bipolar disorder in those who can continue lithium for two years or more. Questions comparing psychiatric and general medical treatments were generated.
对精神病治疗的批评常常涉及将其与一般医学治疗的理想化描述相比较。精神病学治疗被描述为不能逆转疾病,但普通医学中的许多治疗也不能逆转疾病,有些治疗机制尚不清楚。据说,精神科医生开药是为了逆转假设的机制,但一项调查发现,他们通常在临床情况下开药,因为研究表明它是有效的,即使作用机制尚不清楚。据说抗抑郁药是无效的,因为在一组参与者中平均效果很小,但这忽略了一些人将获得显著临床益处的证据。研究表明抗精神病药物对预防精神病复发有效;由于种种原因,戒断性精神病不太可能充分解释这种优势,以证明抗精神病药物无效的说法。尽管锂的研究试验并不完善,包括报道锂戒断引起的躁狂的高发率,但仍有一些证据表明,在急性躁狂和预防双相情感障碍复发方面,锂可以持续两年或更长时间。产生了比较精神病学和一般医学治疗的问题。
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引用次数: 0
Treatments in psychiatry compared to general medicine 精神病学治疗与普通医学的比较
Pub Date : 2019-05-01 DOI: 10.1093/MED/9780198807254.003.0015
A. Huda
There is clear overlap in effectiveness between psychiatric treatments and general medicine medications. Both psychiatric treatments and general medicine medications can be harmful. Mechanisms of action of psychiatric treatments are often obscure or unknown. This is less common in general medicine medication but some of the most commonly prescribed drugs used in general medicine do not cure or act directly on disease mechanisms. Evidence-based psychotherapy is an effective treatment for many mental health conditions; its relative effectiveness compared to psychiatric medication varies depending on the condition. If the client is willing and able to participate in bona fide psychotherapy with evidence of effectiveness, it may be preferable to psychiatric medication as it seems to have less serious adverse effects although more research is needed on harmful adverse effects. Psychotherapy combined with medication is often more effective than either used alone and both types of treatment are complementary, even synergistic, in achieving treatment objectives. Access to psychotherapy is often less easy than access to medication as it is labour intensive, and using medication allows doctors to see many more patients (see Chapter 5). For some conditions and situations, for example, for those unable to participate in psychotherapy, psychiatric treatments are still preferred.
在精神科治疗和普通医学药物的有效性上有明显的重叠。精神科治疗和普通药物治疗都可能有害。精神病治疗的作用机制往往是模糊的或未知的。这在普通医学治疗中不太常见,但普通医学中使用的一些最常用的处方药不能治愈或直接作用于疾病机制。循证心理治疗是许多心理健康状况的有效治疗方法;与精神科药物相比,它的相对有效性因病情而异。如果来访者愿意并能够参与真正的心理治疗,并有证据表明其有效,那么它可能比精神科药物更可取,因为它似乎没有那么严重的副作用,尽管需要更多的有害副作用研究。心理治疗与药物治疗相结合通常比单独使用更有效,在实现治疗目标方面,这两种治疗是互补的,甚至是协同的。获得心理治疗通常比获得药物治疗更不容易,因为它是劳动密集型的,并且使用药物可以让医生看到更多的病人(见第5章)。对于某些条件和情况,例如,对于那些无法参加心理治疗的人,精神治疗仍然是首选。
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引用次数: 0
Variability of clinical picture 临床表现的可变性
Pub Date : 2019-05-01 DOI: 10.1093/MED/9780198807254.003.0010
A. Huda
Psychiatric diagnostic constructs produce highly variable clinical pictures in patients. Amongst the reasons for this are high rates of co-occurrence of different diagnostic constructs, which themselves are often polythetic in nature. People who meet criteria for a diagnostic construct may have little or even no clinical features in common. These diagnostic constructs rely on people meeting the diagnostic criteria having similar qualities to their condition such as similar likelihoods of outcomes/responses to treatments. These highly variable clinical pictures are seen even when clear disease is involved, such as the dementias. General medical diagnostic constructs can also display highly variable clinical pictures even when clear disease processes have been identified. Polythetic diagnostic criteria decided upon by expert committees are also used for general medical diagnostic constructs which can also result in people meeting the same diagnostic criteria having little in common in their clinical pictures. Co-occurrence is also common in general medicine. Psychological formulation does not have to address the issue of variable clinical pictures. Both symptom-based and dimensional classifications can depict variable clinical pictures more accurately than diagnostic constructs but there are pragmatic issues such as suitability for brief appointments or emergency work.
精神病学诊断结构在患者中产生高度可变的临床图像。其中的原因是不同的诊断结构的发生率很高,这本身往往是合成的性质。符合诊断结构标准的人可能很少或甚至没有共同的临床特征。这些诊断结构依赖于符合诊断标准的人具有与其病情相似的品质,例如对治疗结果/反应的相似可能性。即使有明确的疾病,如痴呆,也能看到这些高度可变的临床图像。一般的医学诊断结构也可以显示高度可变的临床图像,即使明确的疾病过程已经确定。由专家委员会决定的综合诊断标准也用于一般医学诊断结构,这也可能导致满足相同诊断标准的人在其临床图片中几乎没有共同点。共同发生在普通医学中也很常见。心理学公式不必解决可变临床图像的问题。基于症状和维度的分类都可以比诊断结构更准确地描述可变的临床图像,但存在实用问题,例如简短预约或紧急工作的适用性。
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引用次数: 0
Spectrums of health 健康谱
Pub Date : 2019-05-01 DOI: 10.1093/MED/9780198807254.003.0009
A. Huda
Many conditions in psychiatry cannot be separated from normality/healthy states (e.g. depression) but even these broad diagnostic constructs may include syndromes like melancholia. There is still a debate as to whether psychotic-like experiences in the community are on a continuum with psychotic symptoms in those meeting diagnostic criteria for psychosis diagnostic constructs. Schizophrenia may exist on a continuum with related conditions (e.g. schizotypal personality disorder). There are differences between people meeting criteria for schizophrenia and healthy controls but none that can be used as a diagnostic test to separate the two, with the possible exception of anomalous self-experiences differentiating schizophrenia spectrum conditions from healthy controls and other diagnostic constructs. Several general medical conditions also exist on a continuum with health with no zones of rarity (e.g. hypertension and type 2 diabetes). Thresholds to meet criteria for these diagnostic constructs are chosen by expert committees often based on risk of developing complications (e.g. myocardial infarctions) and/or whether medical intervention may be beneficial. Even reasonably objective investigations can give abnormal results in healthy people. Concerns about whether thresholds are too low, leading to over-diagnosis, unnecessary treatment, and iatrogenic harm, also exist in general medicine. Other classifications in mental health will need to use thresholds in order to fulfil functions such as administration, research, or access to services. Dimensional classifications are good at representing the many spectrums of mental health.
精神病学中的许多情况不能与正常/健康状态(例如抑郁症)分开,但即使是这些广泛的诊断结构也可能包括像抑郁症这样的综合征。对于那些符合精神病诊断结构诊断标准的人,社区中类似精神病的经历是否与精神病症状是一个连续体,仍然存在争议。精神分裂症可能与相关疾病(如分裂型人格障碍)持续存在。符合精神分裂症标准的人和健康对照者之间存在差异,但没有任何差异可以用作区分两者的诊断测试,可能除了将精神分裂症谱系条件与健康对照者和其他诊断结构区分开来的异常自我体验。若干一般医疗条件也与健康连续存在,没有罕见区(如高血压和2型糖尿病)。满足这些诊断结构标准的阈值通常由专家委员会根据发生并发症的风险(如心肌梗死)和/或医疗干预是否有益来选择。即使是合理客观的调查也会给健康人带来不正常的结果。对于阈值是否过低、导致过度诊断、不必要治疗和医源性伤害的担忧,在普通医学中也存在。精神卫生的其他分类将需要使用阈值,以便履行管理、研究或获得服务等职能。维度分类很好地代表了心理健康的许多领域。
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引用次数: 0
Final conclusions 最终结论
Pub Date : 2019-05-01 DOI: 10.1093/med/9780198807254.003.0016
A. Huda
The medical model in mental health uses diagnostic constructs with attached useful information (e.g. on prognosis or response to treatments) that often identifies areas of spectrums rather than diseases or syndromes. Diagnostic constructs in psychiatry and general medicine overlap for attributes such as clinical utility (e.g. predicting likely outcomes), validity (e.g. whether boundaries exist between different diagnostic constructs), and importance of social factors. There is an overlap in effectiveness between psychiatric and general medicine treatments, and many general medicine medications do not reverse disease processes. Describing the nature of diagnostic constructs can be done by describing the basis of classification and nature of the classified condition. Different mental health classifications have particular strengths and weaknesses for clinical, research, and social functions. Research in mental health may need classifications other than diagnosis to improve understanding of causes and mechanisms and also to develop better diagnostic constructs. As doctors in all specialties will encounter mental health problems there will always be psychiatric diagnostic constructs compatible with their training. The medical model of mental health allows doctors to assess and offer effective treatments to large numbers of patients and provide emergency cover. Mental health research and service provision will always need to address psychosocial issues.
心理健康的医学模式使用附加有用信息(例如关于预后或对治疗的反应)的诊断结构,这些结构通常确定频谱的领域,而不是疾病或综合征。精神病学和普通医学的诊断结构在临床效用(如预测可能的结果)、有效性(如不同诊断结构之间是否存在边界)和社会因素的重要性等属性上重叠。精神科和普通医学治疗的有效性有重叠,而且许多普通医学药物不能逆转疾病进程。描述诊断构念的性质可以通过描述分类的基础和分类条件的性质来完成。不同的心理健康分类在临床、研究和社会功能方面有其独特的优势和劣势。心理健康研究可能需要分类而不是诊断,以提高对原因和机制的理解,并开发更好的诊断结构。由于所有专业的医生都会遇到精神健康问题,因此总会有与他们的培训相适应的精神病学诊断结构。心理健康的医学模式使医生能够对大量病人进行评估并提供有效的治疗,并提供紧急保险。精神卫生研究和服务的提供将始终需要解决社会心理问题。
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引用次数: 0
Criticism of psychiatric diagnosis 精神病诊断批评
Pub Date : 2019-05-01 DOI: 10.1093/MED/9780198807254.003.0006
A. Huda
Criticisms of psychiatric diagnostic constructs from a clinical/scientific view have been made on several points: reliability, such as how often two clinicians agree on the same diagnosis; validity, such as clear separation between diagnostic constructs or presence of objective validators; utility, such as predicting outcomes and treatment responses; implying an inaccurate conception of mental health problems as diseases that also minimizes the influence of social causative factors, high rates of co-occurrence, and association with negative consequences such as stigma. Many psychiatric diagnostic constructs lack validity but often have clinical utility. This clinical utility depends on how the clinician works therefore psychiatric diagnostic constructs are well suited to the medical model but may have little utility for other mental health professionals who work differently or for researchers testing hypotheses. Diagnostic constructs have utility for administrative purposes. The criticisms can be used to generate a set of questions to evaluate psychiatric diagnostic constructs. Psychiatric diagnostic constructs are best compared with general medical diagnostic constructs because they are used for similar purposes in clinical decision-making. A comparison will be made to see if there is no overlap, some overlap, or near total overlap between general medical and psychiatric diagnostic constructs.
从临床/科学的角度对精神病学诊断结构提出了几点批评:可靠性,例如两名临床医生在同一诊断上达成一致的频率;效度,如诊断构念之间的明确分离或客观验证者的存在;效用,如预测结果和治疗反应;这意味着将精神健康问题视为疾病的概念不准确,同时也将社会致病因素的影响降到最低,发病率很高,并与污名化等负面后果有关。许多精神病学诊断结构缺乏有效性,但往往具有临床用途。这种临床效用取决于临床医生如何工作,因此精神病学诊断结构非常适合医学模型,但对于其他工作方式不同的精神卫生专业人员或研究人员测试假设可能没有什么效用。诊断构造用于管理目的。这些批评可以用来产生一组问题来评估精神诊断结构。精神病学诊断构念最好与一般医学诊断构念进行比较,因为它们在临床决策中用于相似的目的。比较一般医学和精神病学诊断结构之间是否没有重叠,有些重叠,或几乎完全重叠。
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引用次数: 3
Explanation of basic concepts of medical terminology 医学术语基本概念的解释
Pub Date : 2019-05-01 DOI: 10.1093/MED/9780198807254.003.0001
A. Huda
People often compare general medicine to psychiatry using false assumptions or incomplete comparative information. Doctors’ role in healthcare relies in part on their sapiental authority, i.e. their knowledge. This sapiental authority relies on developing a medical model to learn and use information. The medical model relies on standardized terminology to aid communication and learning. The medical model allows them to identify problems and recall information on outcomes and treatments. The medical model may also allow explanation of how problems occur and the biopsychosocial model is preferred. Other models of explanation and intervention may also be used and may be superior for certain functions or explanations. The concepts of disease, illness, and health are not clear-cut and often require professional judgements—influenced by culture—based on distress or risk of adverse outcomes to identify examples of, e.g. disease. Condition may be used instead for states that may require medical attention.
人们经常用错误的假设或不完整的比较信息来比较普通医学和精神病学。医生在医疗保健中的作用部分依赖于他们的智力权威,即他们的知识。这种智力权威依赖于开发一种医学模式来学习和使用信息。医学模式依赖于标准化的术语来帮助交流和学习。医学模型允许他们识别问题并回忆有关结果和治疗的信息。医学模型也可以解释问题是如何发生的,生物心理社会模型是首选。其他的解释和干预模式也可以使用,并且对于某些功能或解释可能更优越。疾病、疾病和健康的概念并不明确,往往需要受文化影响,根据痛苦或不良后果风险进行专业判断,以确定疾病等例子。Condition可用于可能需要医疗照顾的状态。
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引用次数: 0
The clinical picture, creating diagnostic constructs, and causation 临床图像,创建诊断结构和因果关系
Pub Date : 2019-05-01 DOI: 10.1093/MED/9780198807254.003.0004
A. Huda
The clinical picture is the doctor’s interpretation based on what has happened to the patient and symptoms, signs, and results of investigations that are available to her. It is created by the interaction of causative factors as well as multiple cultural, interactive, and individual factors. The doctor matches the patient’s clinical picture with the diagnostic construct and the most common elements of an attached clinical picture. Diagnostic constructs based on similarity with the clinical picture may have clinical utility by accumulating information about likely outcomes and responses to treatments. Diagnostic constructs based on common mechanisms (such as changes in structure or processes) and/or causes have greater scientific validity and allow more reliable diagnostic investigations and better prospects of developing superior treatments. Most medical conditions are caused by a combination of causative factors. Proving a factor is causative is complex. One of the best known methods is Austen Hill’s framework. Conditions occur due to combinations of causes, characteristics, and contexts.
临床图景是医生根据患者的情况、症状、体征和可获得的检查结果作出的解释。它是由致病因素的相互作用以及多种文化、互动和个体因素共同作用而产生的。医生将患者的临床图像与诊断结构和附加的临床图像的最常见元素相匹配。基于与临床图像相似性的诊断结构可以通过积累有关可能结果和治疗反应的信息而具有临床效用。基于共同机制(如结构或过程的变化)和/或原因的诊断结构具有更大的科学有效性,并允许更可靠的诊断调查和更好的发展更好的治疗前景。大多数疾病是由多种致病因素共同引起的。证明一个因素是因果关系是很复杂的。最著名的方法之一是奥斯汀·希尔的框架。条件的发生是由于各种原因、特征和环境的综合作用。
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引用次数: 0
Social factors and health 社会因素与健康
Pub Date : 2019-05-01 DOI: 10.1093/MED/9780198807254.003.0013
A. Huda
There is increased risk caused by social difficulties and/or childhood trauma for developing both general medical and mental health conditions, with overlap in similarity of magnitude of some increased risks, although intermediary mechanisms may differ. Social factors are the most important determinants of health status. Reducing social adversity and childhood trauma would improve the physical and mental health of the population. Life events and stresses/hassles are a more specific risk factor for mental health problems. Social factors are often inadequate to explain the nature and severity of people’s mental health problems without taking into account psychobiological factors. Given the greater effect of culture on how mental health conditions are expressed, there is some overlap between psychiatric and general medical diagnostic constructs rather than near total overlap. Mental health conditions do seem associated with greater stigma (some of this seems related to the categorical nature of diagnostic constructs) and also with greater use of coercion than for general medical conditions, but this also occurs for general medical conditions hence the conclusion of some overlap.
社会困难和/或童年创伤造成的一般医疗和精神健康状况的风险增加,有些风险增加的程度相似,但中间机制可能有所不同。社会因素是健康状况的最重要决定因素。减少社会逆境和童年创伤将改善人口的身心健康。生活事件和压力/麻烦是心理健康问题的一个更具体的风险因素。如果不考虑心理生物学因素,社会因素往往不足以解释人们心理健康问题的性质和严重程度。鉴于文化对心理健康状况如何表达的影响更大,精神病学和一般医学诊断结构之间存在一些重叠,而不是几乎完全重叠。精神健康状况似乎确实与更大的耻辱有关(其中一些似乎与诊断结构的分类性质有关),而且与一般医疗状况相比,也与更多地使用胁迫有关,但这种情况也发生在一般医疗状况中,因此得出一些重叠的结论。
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引用次数: 0
Clinical utility of diagnosis 诊断的临床应用
Pub Date : 2019-05-01 DOI: 10.1093/MED/9780198807254.003.0014
A. Huda
There is evidence of overlap between psychiatric and general medical constructs for clinical utility particularly for variability of outcomes; use of diagnostic criteria decided by committees of experts and use of clinical information apart from the diagnosis. For psychiatric diagnostic constructs there is evidence of some differences in outcomes and responses to treatments between different diagnostic constructs. On the other hand, it is easier to directly measure variables relevant for clinical purposes in general medicine. Therefore, for all the questions the conclusion of some (not near total overlap) seems fairest. Psychiatric diagnostic constructs can have clinical utility if there is useful information attached e.g. on likely range of outcomes or likely responses to treatments. Psychological formulation has utility but is unlikely to be helpful in all clinical scenarios or ways of working. Dimension or symptom based classification may have greater validity, still involve categorical choices and have limitations in clinical utility. Alternative classifications have compatibility problems with the healthcare system for collective administrative data, statistics or for other social functions such as access to benefits.
有证据表明,精神病学和一般医学结构在临床应用方面存在重叠,特别是在结果的可变性方面;使用由专家委员会决定的诊断标准和使用除诊断外的临床信息。对于精神病学诊断构念,有证据表明不同诊断构念之间的结果和治疗反应存在一些差异。另一方面,在普通医学中更容易直接测量与临床目的相关的变量。因此,对于所有的问题,一些结论(不是完全重叠)似乎是最公平的。如果附加了有用的信息,例如关于可能的结果范围或对治疗的可能反应,精神病学诊断结构可以具有临床效用。心理学公式具有实用性,但不太可能对所有临床情景或工作方式都有帮助。基于维度或症状的分类可能更有效,但仍涉及分类选择,在临床应用中有局限性。替代分类在集体行政数据、统计数据或其他社会功能(如获得福利)方面与医疗保健系统存在兼容性问题。
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引用次数: 0
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The Medical Model in Mental Health
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