Pub Date : 2023-07-19DOI: 10.1007/s12609-023-00499-x
Aishwarya Shah, N. Gerber
{"title":"Radiation Management of DCIS and Elimination of RT in Low-risk Disease","authors":"Aishwarya Shah, N. Gerber","doi":"10.1007/s12609-023-00499-x","DOIUrl":"https://doi.org/10.1007/s12609-023-00499-x","url":null,"abstract":"","PeriodicalId":10769,"journal":{"name":"Current Breast Cancer Reports","volume":"15 1","pages":"175 - 184"},"PeriodicalIF":0.9,"publicationDate":"2023-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48483463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-15DOI: 10.1007/s12609-023-00498-y
C. Hui, F. Dirbas, K. Horst
{"title":"Management of Local–Regional Recurrence of Breast Cancer","authors":"C. Hui, F. Dirbas, K. Horst","doi":"10.1007/s12609-023-00498-y","DOIUrl":"https://doi.org/10.1007/s12609-023-00498-y","url":null,"abstract":"","PeriodicalId":10769,"journal":{"name":"Current Breast Cancer Reports","volume":"15 1","pages":"185 - 195"},"PeriodicalIF":0.9,"publicationDate":"2023-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49078044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-12DOI: 10.1007/s12609-023-00500-7
Sarah J Wood, Devon Foster, J. Meisel
{"title":"Optimizing the Treatment for Pregnancy-Associated Breast Cancer: a Case Example and Review of the Literature","authors":"Sarah J Wood, Devon Foster, J. Meisel","doi":"10.1007/s12609-023-00500-7","DOIUrl":"https://doi.org/10.1007/s12609-023-00500-7","url":null,"abstract":"","PeriodicalId":10769,"journal":{"name":"Current Breast Cancer Reports","volume":"15 1","pages":"153 - 159"},"PeriodicalIF":0.9,"publicationDate":"2023-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43399680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-05DOI: 10.1007/s12609-023-00497-z
Brian Figueroa, F. Vicini, C. Shah
{"title":"Partial Breast Radiation","authors":"Brian Figueroa, F. Vicini, C. Shah","doi":"10.1007/s12609-023-00497-z","DOIUrl":"https://doi.org/10.1007/s12609-023-00497-z","url":null,"abstract":"","PeriodicalId":10769,"journal":{"name":"Current Breast Cancer Reports","volume":"15 1","pages":"168 - 174"},"PeriodicalIF":0.9,"publicationDate":"2023-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44110914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-03DOI: 10.1007/s12609-023-00495-1
G. Freedman
{"title":"Fractionation Approaches in Whole Breast RT","authors":"G. Freedman","doi":"10.1007/s12609-023-00495-1","DOIUrl":"https://doi.org/10.1007/s12609-023-00495-1","url":null,"abstract":"","PeriodicalId":10769,"journal":{"name":"Current Breast Cancer Reports","volume":"15 1","pages":"160 - 167"},"PeriodicalIF":0.9,"publicationDate":"2023-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45924129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-29DOI: 10.1007/s12609-023-00492-4
M. Matossian, Nan Chen, R. Nanda
{"title":"Exploiting Therapeutic Vulnerabilities in Triple-Negative Breast Cancer: Successes, Challenges, and Opportunities","authors":"M. Matossian, Nan Chen, R. Nanda","doi":"10.1007/s12609-023-00492-4","DOIUrl":"https://doi.org/10.1007/s12609-023-00492-4","url":null,"abstract":"","PeriodicalId":10769,"journal":{"name":"Current Breast Cancer Reports","volume":"15 1","pages":"266 - 278"},"PeriodicalIF":0.9,"publicationDate":"2023-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43806669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-24DOI: 10.1007/s12609-023-00494-2
Quratulain Sabih, Kristin Lupinacci, E. Diego
{"title":"Current Recommendations and Role of Breast Conservation Surgery for Multifocal or Multicentric Breast Cancer","authors":"Quratulain Sabih, Kristin Lupinacci, E. Diego","doi":"10.1007/s12609-023-00494-2","DOIUrl":"https://doi.org/10.1007/s12609-023-00494-2","url":null,"abstract":"","PeriodicalId":10769,"journal":{"name":"Current Breast Cancer Reports","volume":"15 1","pages":"279 - 287"},"PeriodicalIF":0.9,"publicationDate":"2023-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41634296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-17DOI: 10.1007/s12609-023-00493-3
Xiaojie Zhang, K. Yeung
{"title":"Metastatic Triple-Negative Breast Cancer","authors":"Xiaojie Zhang, K. Yeung","doi":"10.1007/s12609-023-00493-3","DOIUrl":"https://doi.org/10.1007/s12609-023-00493-3","url":null,"abstract":"","PeriodicalId":10769,"journal":{"name":"Current Breast Cancer Reports","volume":"15 1","pages":"288 - 297"},"PeriodicalIF":0.9,"publicationDate":"2023-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42126405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-01DOI: 10.1007/s12609-023-00491-5
Stav Brown, Adana C Campbell, Kevin Kuonqui, Ananta Sarker, Hyeung Ju Park, Jinyeon Shin, Raghu P Kataru, Michelle Coriddi, Joseph H Dayan, Babak J Mehrara
Purpose of review: This review aims to summarize the current knowledge regarding the pharmacological interventions studied in both experimental and clinical trials for secondary lymphedema.
Recent findings: Lymphedema is a progressive disease that results in tissue swelling, pain, and functional disability. The most common cause of secondary lymphedema in developed countries is an iatrogenic injury to the lymphatic system during cancer treatment. Despite its high incidence and severe sequelae, lymphedema is usually treated with palliative options such as compression and physical therapy. However, recent studies on the pathophysiology of lymphedema have explored pharmacological treatments in preclinical and early phase clinical trials.
Summary: Many potential treatment options for lymphedema have been explored throughout the past two decades including systemic agents and topical approaches to decrease the potential toxicity of systemic treatment. Treatment strategies including lymphangiogenic factors, anti-inflammatory agents, and anti-fibrotic therapies may be used independently or in conjunction with surgical approaches.
{"title":"The Future of Lymphedema: Potential Therapeutic Targets for Treatment.","authors":"Stav Brown, Adana C Campbell, Kevin Kuonqui, Ananta Sarker, Hyeung Ju Park, Jinyeon Shin, Raghu P Kataru, Michelle Coriddi, Joseph H Dayan, Babak J Mehrara","doi":"10.1007/s12609-023-00491-5","DOIUrl":"10.1007/s12609-023-00491-5","url":null,"abstract":"<p><strong>Purpose of review: </strong>This review aims to summarize the current knowledge regarding the pharmacological interventions studied in both experimental and clinical trials for secondary lymphedema.</p><p><strong>Recent findings: </strong>Lymphedema is a progressive disease that results in tissue swelling, pain, and functional disability. The most common cause of secondary lymphedema in developed countries is an iatrogenic injury to the lymphatic system during cancer treatment. Despite its high incidence and severe sequelae, lymphedema is usually treated with palliative options such as compression and physical therapy. However, recent studies on the pathophysiology of lymphedema have explored pharmacological treatments in preclinical and early phase clinical trials.</p><p><strong>Summary: </strong>Many potential treatment options for lymphedema have been explored throughout the past two decades including systemic agents and topical approaches to decrease the potential toxicity of systemic treatment. Treatment strategies including lymphangiogenic factors, anti-inflammatory agents, and anti-fibrotic therapies may be used independently or in conjunction with surgical approaches.</p>","PeriodicalId":10769,"journal":{"name":"Current Breast Cancer Reports","volume":" ","pages":"1-9"},"PeriodicalIF":0.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233555/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9717185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-24DOI: 10.1007/s12609-023-00488-0
D. Das, M. Iyer, E. T. Roussos Torres, F. Chow, J. Neman
{"title":"Breast-to-Brain Metastasis: from Microenvironment to Plasticity","authors":"D. Das, M. Iyer, E. T. Roussos Torres, F. Chow, J. Neman","doi":"10.1007/s12609-023-00488-0","DOIUrl":"https://doi.org/10.1007/s12609-023-00488-0","url":null,"abstract":"","PeriodicalId":10769,"journal":{"name":"Current Breast Cancer Reports","volume":"15 1","pages":"142 - 151"},"PeriodicalIF":0.9,"publicationDate":"2023-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42793281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}