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Approach to acute agitation in the pediatric emergency department. 儿科急诊室处理急性躁动的方法。
IF 3.6 3区 医学 Q1 Medicine Pub Date : 2024-06-01 Epub Date: 2024-01-31 DOI: 10.1097/MOP.0000000000001337
Ashley A Foster, Mohsen Saidinejad, Joyce Li

Purpose of review: The complexity of pediatric mental and behavioral health (MBH) complaints presenting to emergency departments (EDs) is increasing at an alarming rate. Children may present with agitation or develop agitation during the ED visit. This causes significant distress and may lead to injury of the child, caregivers, or medical staff. This review will focus on providing safe, patient-centered care to children with acute agitation in the ED.

Recent findings: Approaching a child with acute agitation in the ED requires elucidation on the cause and potential triggers of agitation for optimal management. The first step in a patient-centered approach is to use the least restrictive means with behavioral and environmental strategies. Restraint use (pharmacologic or physical restraint) should be reserved where these modifications do not result in adequate de-escalation. The provider should proceed with medications first, using the child's medication history as a guide. The use of physical restraint is a last resort to assure the safety concerns of the child, family, or staff, with a goal of minimizing restraint time.

Summary: Children are increasingly presenting to EDs with acute agitation. By focusing primarily on behavioral de-escalation and medication strategies, clinicians can provide safe, patient-centered care around these events.

审查目的:急诊科(ED)接诊的儿科精神和行为健康(MBH)主诉的复杂程度正在以惊人的速度增加。在急诊室就诊期间,儿童可能会出现躁动或产生躁动。这会造成严重的痛苦,并可能导致儿童、护理人员或医务人员受伤。本综述将重点讨论如何在急诊室为患有急性躁动的儿童提供安全、以患者为中心的护理:在急诊室接诊急性躁动患儿时,需要阐明躁动的原因和潜在诱因,以便进行最佳处理。以患者为中心的方法的第一步是使用限制性最小的行为和环境策略。如果这些方法不能充分缓解躁动,则应保留使用约束手段(药物或物理约束)。服务提供者应首先使用药物,并以儿童的用药史为指导。使用物理约束是确保儿童、家人或工作人员安全的最后手段,目的是最大限度地减少约束时间。通过主要关注行为降级和药物治疗策略,临床医生可以围绕这些事件提供以患者为中心的安全护理。
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引用次数: 0
Pediatric pulmonology: progress at the intersection of medicine and discovery. 小儿肺脏病学:医学与发现交汇的进展。
IF 2.2 3区 医学 Q2 PEDIATRICS Pub Date : 2024-06-01 Epub Date: 2024-05-01 DOI: 10.1097/MOP.0000000000001344
David N Cornfield
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引用次数: 0
Engaging caregivers to prevent substance use by at-risk adolescents in pediatric primary care. 在儿科初级保健中让护理人员参与预防高危青少年使用药物。
IF 3.6 3区 医学 Q1 Medicine Pub Date : 2024-04-15 DOI: 10.1097/MOP.0000000000001359
Jessica B. Calihan, Pamela Matson
PURPOSE OF REVIEWImproving adolescent substance use prevention and treatment is an urgent public health priority in the United States. Current intervention models do not address how adolescents with a history of caregiver substance use are at particular risk for problematic substance use. We, therefore, reviewed the evidence on adolescent substance use prevention programs integrating caregiver-focused components and propose opportunities to incorporate adaptations of existing programs into pediatric primary care to improve outcomes for at-risk adolescents exposed to caregiver substance use.RECENT FINDINGSThere are multiple evidence-based universal prevention programs that target adolescent substance use and incorporate caregivers; however, these programs do not address the specific concerns of caregivers with substance use. Caregiver-focused programs efficaciously address family and child risk factors for adolescent substance use but are not accessible to many families and have not been longitudinally studied to assess impact on adolescent substance use.SUMMARYAdaptation of existing prevention programs to pediatric primary care settings may open opportunities to improve engagement of families with caregiver substance use in targeted prevention strategies. Family Screening, Brief Intervention, and Referral to Treatment (F-SBIRT) is one model that can be incorporated into pediatric primary care to contextualize evidence-based practices to address substance use in a family-focused approach. To develop F-SBIRT, further research is needed to validate caregiver-focused screening tools, determine brief intervention (BI) best practices, and adapt existing evidence-based and caregiver-focused adolescent prevention programs for use with caregivers with substance use in pediatric primary care settings.
综述目的改善青少年药物使用的预防和治疗是美国公共卫生领域的当务之急。目前的干预模式并没有解决有照顾者药物使用史的青少年如何面临问题药物使用的特殊风险。因此,我们回顾了有关青少年药物使用预防计划的证据,其中包含了以照顾者为重点的内容,并提出了将现有计划调整纳入儿科初级保健的机会,以改善面临照顾者药物使用风险的青少年的治疗效果。以照顾者为重点的计划有效地解决了青少年药物使用的家庭和儿童风险因素,但许多家庭并不了解这些计划,也没有进行纵向研究以评估其对青少年药物使用的影响。家庭筛查、简单干预和转介治疗(F-SBIRT)是一种可纳入儿科初级保健的模式,可将基于证据的实践结合起来,以家庭为中心的方法解决药物使用问题。要开发 F-SBIRT,需要进一步研究验证以照顾者为重点的筛查工具,确定简短干预(BI)的最佳实践,并调整现有的以证据为基础、以照顾者为重点的青少年预防计划,以便在儿科初级保健环境中用于药物使用的照顾者。
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引用次数: 0
Disordered eating in adolescents with type 1 diabetes: risk factors and screening recommendations. 1 型糖尿病青少年的饮食紊乱:风险因素和筛查建议。
IF 3.6 3区 医学 Q1 Medicine Pub Date : 2024-04-15 DOI: 10.1097/MOP.0000000000001353
Emma Chad-Friedman, Lauren Clary, Grace Jhe
PURPOSE OF REVIEWAdolescents with Type 1 diabetes (T1D) are at significantly greater risk for disordered eating behaviors compared to their peers without T1D. Given that this is a dangerous and potentially lethal combination, this review aims to support pediatric medical providers in increasing competence in identification, assessment, and prevention of disordered eating behaviors in adolescents with T1D.RECENT FINDINGSThis review provides an up-to-date synthesis of unique risk factors for disordered eating behaviors in adolescents with T1D, including the daily diabetes management tasks, effects of insulin on weight and hunger, family conflict, and reinforcement from their environment for disordered behaviors. This review recommends two brief screening tools, the Diabetes Eating Problems Survey-Revised (DEPS-R) and Modified SCOFF (mSCOFF), to be used in busy practices; it also provides practical strategies for providersto use with patients in the form of effective, nonjudgmental language.SUMMARYA clear understanding of unique experiences impacting adolescents with T1D may increase use of evidence-based screening tools and identification of disordered eating behaviors among a high-risk population in clinic/practice. In addition, providers' intentional use of nonjudgmental and de-stigmatizing language may lead to more positive interactions for adolescents and willingness to engage in further treatment.
综述目的1 型糖尿病 (T1D) 青少年与非 T1D 青少年相比,发生饮食紊乱行为的风险明显更高。鉴于这是一种危险且可能致命的组合,本综述旨在支持儿科医疗服务提供者提高识别、评估和预防 T1D 青少年饮食失调行为的能力。最新发现本综述对 T1D 青少年饮食失调行为的独特风险因素进行了最新综述,包括日常糖尿病管理任务、胰岛素对体重和饥饿的影响、家庭冲突以及环境对失调行为的强化。本综述推荐了两种简短的筛查工具,即《糖尿病饮食问题调查-修订版》(DEPS-R)和《改良 SCOFF》(mSCOFF),可在繁忙的临床实践中使用;本综述还提供了实用的策略,供医疗服务提供者以有效、非评判性语言的形式用于患者。此外,医疗服务提供者有意识地使用非评判性和去污名化的语言可能会为青少年带来更积极的互动,并使他们愿意接受进一步的治疗。
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引用次数: 0
HIV preexposure prophylaxis in adolescents and young adults: an update. 青少年和年轻成年人的艾滋病毒暴露前预防:最新情况。
IF 3.6 3区 医学 Q1 Medicine Pub Date : 2024-04-11 DOI: 10.1097/MOP.0000000000001357
Caitlin Camfield, Yolanda N Evans, Raaka G Kumbhakar
PURPOSE OF REVIEWThis review provides an update of evidence for HIV preexposure prophylaxis (PrEP), including efficacy and safety of newly available medications. It discusses barriers to care that are unique to adolescents and young adults as well as interventions that may help increase uptake, adherence, and retention in care.RECENT FINDINGSTenofovir alafenamide-emtricitabine and cabotegravir are both newly approved medications for the prevention of HIV and are well tolerated and effective for adolescents. These medications, along with tenofovir disoproxil-emtricitabine, offer a variety of PrEP options to choose from.SUMMARYAdolescents and young adults have many options when it comes to HIV prevention, but barriers persist in terms of uptake and adherence to PrEP and retention in care. Technology-based interventions, provider education, navigation support, and multiple access options are all tools to help increase PrEP use in young people.
综述目的本综述提供了有关艾滋病暴露前预防(PrEP)的最新证据,包括新上市药物的疗效和安全性。本综述还讨论了青少年和年轻成年人在接受治疗时遇到的障碍,以及有助于提高接受率、依从性和保留率的干预措施。这些药物与替诺福韦酯-恩曲他滨一起提供了多种 PrEP 选择。摘要青少年和年轻成年人在预防 HIV 方面有很多选择,但在接受和坚持 PrEP 以及继续接受护理方面仍存在障碍。以技术为基础的干预措施、医疗服务提供者教育、导航支持和多种获取方式都是有助于提高 PrEP 在年轻人中使用率的工具。
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引用次数: 0
Genetic therapies and respiratory outcomes in patients with neuromuscular disease. 神经肌肉疾病患者的基因疗法和呼吸系统预后。
IF 3.6 3区 医学 Q1 Medicine Pub Date : 2024-04-09 DOI: 10.1097/MOP.0000000000001352
Diana Chen, Jeff Ni, MyMy Buu
PURPOSE OF REVIEWGenetic therapies made a significant impact to the clinical course of patients with spinal muscular atrophy and Duchenne muscular dystrophy. Clinicians and therapists who care for these patients want to know the changes in respiratory sequelae and implications for clinical care for treated patients.RECENT FINDINGSDifferent genetic therapy approaches have been developed to replace the deficient protein product in spinal muscular atrophy and Duchenne muscular dystrophy. The natural history of these conditions needed to be understood in order to design clinical trials. Respiratory parameters were not the primary outcome measures for the clinical trials. The impact of these therapies is described in subsequent clinical trial reports or real-world data.SUMMARYGenetic therapies are able to stabilize or improve the respiratory sequelae in patients with spinal muscular atrophy and Duchenne muscular dystrophy. Standardized reporting of these outcomes is needed to help inform the future revisions of clinical standards of care and practice guidelines.
综述目的基因疗法对脊髓性肌萎缩症和杜氏肌营养不良症患者的临床病程产生了重大影响。护理这些患者的临床医生和治疗师希望了解呼吸系统后遗症的变化以及对治疗患者临床护理的影响。为了设计临床试验,需要了解这些疾病的自然病史。呼吸参数并非临床试验的主要结果指标。摘要基因疗法能够稳定或改善脊髓性肌萎缩症和杜氏肌营养不良症患者的呼吸系统后遗症。需要对这些结果进行标准化报告,以便为今后修订临床治疗标准和实践指南提供参考。
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引用次数: 0
Practical guidelines for eating disorder risk mitigation in patients undergoing obesity treatment for the pediatric provider. 为接受肥胖症治疗的患者提供减轻饮食失调风险的实用指南。
IF 3.6 3区 医学 Q1 Medicine Pub Date : 2024-04-08 DOI: 10.1097/MOP.0000000000001356
Katelyn Gordon, Abigail Matthews, M. Zeller, Jessica Lin
PURPOSE OF REVIEWPediatric obesity is a growing concern globally. Patients with a history of overweight/obesity often experience stigmatization, especially in the healthcare setting, and are at increased risk of developing psychological comorbidities including eating disorders. This review appraises the most recent studies evaluating eating disorder risk in youth undergoing treatment for obesity, identifies gaps in the literature, and offers practical guidelines to pediatric providers regarding the management of this population.RECENT FINDINGSRecent studies suggest that structured weight management programs may decrease the risk of and/or improve symptoms of certain eating disorders such as binge eating disorder and bulimia nervosa. There is a paucity of research on some components of obesity management such as obesity pharmacotherapeutics and eating disorder risk.SUMMARYChildren and adolescents with obesity are a psychologically vulnerable population with increased risk for the development of eating disorders. Further study is needed to evaluate general risk in the setting of specialized and primary care obesity interventions and develop appropriate screening and mitigation tools. Some evidence-based strategies can aid pediatric providers in both weight management and eating disorder prevention and risk assessment.
综述目的 儿童肥胖症是全球日益关注的问题。有超重/肥胖病史的患者往往会受到鄙视,尤其是在医疗环境中,而且患上包括饮食失调在内的心理并发症的风险也会增加。本综述评估了最近对接受肥胖症治疗的青少年饮食失调风险进行评估的研究,指出了文献中的不足之处,并为儿科医疗人员提供了有关这类人群管理的实用指南。最近的研究结果表明,有组织的体重管理计划可降低罹患某些饮食失调症(如暴饮暴食症和神经性贪食症)的风险和/或改善其症状。有关肥胖症管理的某些内容,如肥胖症药物治疗和饮食失调风险的研究还很少。需要进行进一步研究,以评估肥胖症专科和初级保健干预环境下的一般风险,并开发适当的筛查和缓解工具。一些循证策略可以帮助儿科医疗人员进行体重管理、饮食失调预防和风险评估。
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引用次数: 0
Emerging therapies for childhood-onset movement disorders. 治疗儿童期运动障碍的新兴疗法。
IF 3.6 3区 医学 Q1 Medicine Pub Date : 2024-04-05 DOI: 10.1097/MOP.0000000000001354
Lindsey Vogt, Vicente Quiroz, D. Ebrahimi‐Fakhari
PURPOSE OF REVIEWWe highlight novel and emerging therapies in the treatment of childhood-onset movement disorders. We structured this review by therapeutic entity (small molecule drugs, RNA-targeted therapeutics, gene replacement therapy, and neuromodulation), recognizing that there are two main approaches to treatment: symptomatic (based on phenomenology) and molecular mechanism-based therapy or 'precision medicine' (which is disease-modifying).RECENT FINDINGSWe highlight reports of new small molecule drugs for Tourette syndrome, Friedreich's ataxia and Rett syndrome. We also discuss developments in gene therapy for aromatic l-amino acid decarboxylase deficiency and hereditary spastic paraplegia, as well as current work exploring optimization of deep brain stimulation and lesioning with focused ultrasound.SUMMARYChildhood-onset movement disorders have traditionally been treated symptomatically based on phenomenology, but focus has recently shifted toward targeted molecular mechanism-based therapeutics. The development of precision therapies is driven by increasing capabilities for genetic testing and a better delineation of the underlying disease mechanisms. We highlight novel and exciting approaches to the treatment of genetic childhood-onset movement disorders while also discussing general challenges in therapy development for rare diseases. We provide a framework for molecular mechanism-based treatment approaches, a summary of specific treatments for various movement disorders, and a clinical trial readiness framework.
综述目的我们重点介绍了治疗儿童期运动障碍的新型疗法和新兴疗法。我们按照治疗实体(小分子药物、RNA 靶向疗法、基因替代疗法和神经调节)来组织本综述,并认识到治疗有两种主要方法:对症疗法(基于现象学)和基于分子机制的疗法或 "精准医学"(可改变疾病)。我们还讨论了芳香族 l- 氨基酸脱羧酶缺乏症和遗传性痉挛性截瘫的基因治疗进展,以及目前探索优化脑深部刺激和聚焦超声病变的工作。摘要儿童发病型运动障碍症传统上是根据现象进行对症治疗,但最近的重点已转向基于分子机制的靶向治疗。基因检测能力的不断提高以及对潜在疾病机理的深入研究推动了精准疗法的发展。我们重点介绍了治疗遗传性儿童期运动障碍的新颖而令人兴奋的方法,同时还讨论了罕见病疗法开发中的一般挑战。我们提供了基于分子机制的治疗方法框架、各种运动障碍的具体治疗方法摘要以及临床试验准备框架。
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引用次数: 0
Current progress in international pediatric emergency medicine. 国际儿科急诊医学的最新进展。
IF 3.6 3区 医学 Q1 Medicine Pub Date : 2024-04-05 DOI: 10.1097/MOP.0000000000001355
Camilo E Gutiérrez, Rodrick Lim, Simon Chu
PURPOSE OF REVIEWOver the past four decades, pediatric emergency Medicine (PEM) has witnessed significant global development, with a notable increase in training programs and official recognition by regulatory bodies. However, disparities persist in the recognition of PEM as an independent subspecialty, availability of training programs on a global scale, academic recognition, and the ability to provide high-quality care to children worldwide. There is paucity of published literature regarding development of PEM globally. This review explores the current trends and challenges in international pediatric emergency medicine.RECENT FINDINGSCurrent trends in international pediatric emergency medicine encompass the provision of training in pediatric-focused emergency and acute care, increased propagation of evidence-based guidelines specific to the care of children, the growth of collaborative research networks and interest groups within national and international societies. Simultaneously, the field continues to face challenges such as the lack of recognition, inequities in access, and a lack of dissemination of global PEM initiatives.SUMMARYWhile recent advancements have significantly enhanced the state of international pediatric emergency medicine, including pediatric specific research networks and training programs, barriers still hinder its overall quality. Many of these obstacles are not unique to pediatric emergency medicine but are directly affected by financial disparities and lack of governmental and public recognition of the essential role of pediatric emergency care.
综述目的在过去的四十年里,儿科急诊医学(PEM)在全球范围内得到了长足的发展,培训项目显著增加,并得到了监管机构的正式认可。然而,在承认儿科急诊医学是一个独立的亚专科、在全球范围内提供培训项目、学术认可以及为全球儿童提供高质量医疗服务的能力方面,差距依然存在。目前,有关全球 PEM 发展的公开文献还很少。本综述探讨了当前国际儿科急诊医学的发展趋势和挑战。当前国际儿科急诊医学的发展趋势包括:提供以儿科为重点的急诊和急性病护理培训、加强宣传以证据为基础的儿童护理指南、在国家和国际学会内发展合作研究网络和兴趣小组。同时,该领域仍面临着一些挑战,如缺乏认可、就医机会不平等以及缺乏对全球儿科急诊医学计划的宣传等。摘要尽管最近的进步极大地提升了国际儿科急诊医学的水平,包括儿科特定的研究网络和培训计划,但仍有一些障碍阻碍了其整体质量的提高。其中许多障碍并非儿科急诊医学所独有,而是直接受到了财政差距以及政府和公众对儿科急诊重要作用认识不足的影响。
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引用次数: 0
Revisiting dexamethasone use in the pediatric emergency department. 重新审视地塞米松在儿科急诊中的使用。
IF 3.6 3区 医学 Q1 Medicine Pub Date : 2024-04-02 DOI: 10.1097/MOP.0000000000001351
Rebecca Weinstein, Catherine E Naber, Kristina Brumme
PURPOSE OF REVIEWDexamethasone is an essential treatment for common pediatric inflammatory, airway, and respiratory conditions. We aim to provide up-to-date recommendations for treatment of anaphylaxis, croup, coronavirus disease, multisystem inflammatory syndrome in children, and asthma with dexamethasone for use in the pediatric emergency department.RECENT FINDINGSLiterature largely continues to support the use of dexamethasone in most of the above conditions, however, recommendations for dosing and duration are evolving.SUMMARYThe findings discussed in this review will enable pediatric emergency medicine providers to use dexamethasone effectively as treatment of common pediatric conditions and minimize the occurrence of side-effects caused by gratuitous corticosteroid use.
综述目的地塞米松是治疗常见儿科炎症、气道和呼吸道疾病的基本药物。我们旨在为儿科急诊使用地塞米松治疗过敏性休克、咳嗽、冠状病毒病、儿童多系统炎症综合征和哮喘提供最新建议。摘要本综述中讨论的研究结果将使儿科急诊医生能够有效地使用地塞米松治疗常见的儿科疾病,并最大限度地减少因无偿使用皮质类固醇而导致的副作用。
{"title":"Revisiting dexamethasone use in the pediatric emergency department.","authors":"Rebecca Weinstein, Catherine E Naber, Kristina Brumme","doi":"10.1097/MOP.0000000000001351","DOIUrl":"https://doi.org/10.1097/MOP.0000000000001351","url":null,"abstract":"PURPOSE OF REVIEW\u0000Dexamethasone is an essential treatment for common pediatric inflammatory, airway, and respiratory conditions. We aim to provide up-to-date recommendations for treatment of anaphylaxis, croup, coronavirus disease, multisystem inflammatory syndrome in children, and asthma with dexamethasone for use in the pediatric emergency department.\u0000\u0000\u0000RECENT FINDINGS\u0000Literature largely continues to support the use of dexamethasone in most of the above conditions, however, recommendations for dosing and duration are evolving.\u0000\u0000\u0000SUMMARY\u0000The findings discussed in this review will enable pediatric emergency medicine providers to use dexamethasone effectively as treatment of common pediatric conditions and minimize the occurrence of side-effects caused by gratuitous corticosteroid use.","PeriodicalId":10985,"journal":{"name":"Current opinion in pediatrics","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140755398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Current opinion in pediatrics
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