Aim/introduction: This study aims to investigate the prevalence and characteristics of diabetic symmetric sensorimotor polyneuropathy (DSPN) in patients with type 2 diabetes registered in the Japan Diabetes Complication and its Prevention Prospective (JDCP) study.
Materials and methods: In the study, 6338 patients with diabetes who had been treated by diabetes specialists were registered in 2007-2009. Of these, patients with type 2 diabetes who could be evaluated for DSPN were analyzed using t test, chi-square test, and logistic regression analyses. DSPN was diagnosed using the Simple Diagnostic Criteria for Diabetic Polyneuropathy proposed by the Diabetic Neuropathy Study Group in Japan.
Results: Of the total participants, 5451 patients (mean age 61.4 years old and duration of diabetes 10.8 years) were analyzed. Based on the criteria, 35.8% of patients were diagnosed with DSPN. The prevalence of sensory symptoms was 25.8%. The following factors increased risk for DSPN: age [odds ratio (OR) 1.57, 95% confidence intervals (CI) 1.42-1.73], duration of diabetes (OR 1.32, 95% CI 1.21-1.43), body mass index (OR 1.19, 95% CI 1.09-1.30), systolic blood pressure (OR 1.06, 95% CI 1.01-1.10), hemoglobin A1c (OR 1.15, 95% CI 1.09-1.22), biguanides (OR 1.22, 95% CI 1.06-1.39), and insulin therapy (OR 1.59, 95% CI 1.36-1.84). The following factors decreased risk for DSPN: total cholesterol (OR 0.98, 95% CI 0.96-1.00) and exercise therapy (OR 0.85, 95% CI 0.73-0.98).
Conclusions: The baseline survey clarified the prevalence and characteristics of DSPN in Japanese patients with type 2 diabetes. The survey also revealed the risk factors of DSPN.
目的/简介：本研究旨在调查在日本糖尿病并发症及其预防前瞻性研究（JDCP）中登记的2型糖尿病患者中糖尿病对称性感觉运动多发性神经病（DSPN）的患病率和特征：在这项研究中，登记了 6338 名在 2007-2009 年期间接受过糖尿病专科医生治疗的糖尿病患者。采用t检验、卡方检验和逻辑回归分析法对其中可评估为DSPN的2型糖尿病患者进行了分析。DSPN 的诊断采用日本糖尿病神经病变研究小组提出的糖尿病多发性神经病变简易诊断标准：在所有参与者中，对 5451 名患者（平均年龄 61.4 岁，糖尿病病程 10.8 年）进行了分析。根据标准，35.8% 的患者被诊断为 DSPN。感觉症状的发病率为 25.8%。以下因素增加了罹患 DSPN 的风险：年龄[几率比（OR）1.57，95% 置信区间（CI）1.42-1.73]、糖尿病病程（OR 1.32，95% CI 1.21-1.43）、体重指数（OR 1.19，95% CI 1.09-1.30）、收缩压（OR 1.06，95% CI 1.01-1.10）、血红蛋白 A1c（OR 1.15，95% CI 1.09-1.22）、双胍类药物（OR 1.22，95% CI 1.06-1.39）和胰岛素治疗（OR 1.59，95% CI 1.36-1.84）。以下因素降低了 DSPN 的风险：总胆固醇（OR 0.98，95% CI 0.96-1.00）和运动疗法（OR 0.85，95% CI 0.73-0.98）：基线调查明确了日本 2 型糖尿病患者中 DSPN 的患病率和特征。结论：基线调查明确了日本 2 型糖尿病患者中 DSPN 的患病率和特征，还揭示了 DSPN 的风险因素。
{"title":"Prevalence and characteristics of diabetic symmetric sensorimotor polyneuropathy in Japanese patients with type 2 diabetes: the Japan Diabetes Complication and its Prevention Prospective study (JDCP study 10).","authors":"Hideki Kamiya, Tatsuhito Himeno, Atsuko Watarai, Masayuki Baba, Rimei Nishimura, Naoko Tajima, Jiro Nakamura","doi":"10.1007/s13340-023-00678-2","DOIUrl":"10.1007/s13340-023-00678-2","url":null,"abstract":"<p><strong>Aim/introduction: </strong>This study aims to investigate the prevalence and characteristics of diabetic symmetric sensorimotor polyneuropathy (DSPN) in patients with type 2 diabetes registered in the Japan Diabetes Complication and its Prevention Prospective (JDCP) study.</p><p><strong>Materials and methods: </strong>In the study, 6338 patients with diabetes who had been treated by diabetes specialists were registered in 2007-2009. Of these, patients with type 2 diabetes who could be evaluated for DSPN were analyzed using <i>t</i> test, chi-square test, and logistic regression analyses. DSPN was diagnosed using the Simple Diagnostic Criteria for Diabetic Polyneuropathy proposed by the Diabetic Neuropathy Study Group in Japan.</p><p><strong>Results: </strong>Of the total participants, 5451 patients (mean age 61.4 years old and duration of diabetes 10.8 years) were analyzed. Based on the criteria, 35.8% of patients were diagnosed with DSPN. The prevalence of sensory symptoms was 25.8%. The following factors increased risk for DSPN: age [odds ratio (OR) 1.57, 95% confidence intervals (CI) 1.42-1.73], duration of diabetes (OR 1.32, 95% CI 1.21-1.43), body mass index (OR 1.19, 95% CI 1.09-1.30), systolic blood pressure (OR 1.06, 95% CI 1.01-1.10), hemoglobin A1c (OR 1.15, 95% CI 1.09-1.22), biguanides (OR 1.22, 95% CI 1.06-1.39), and insulin therapy (OR 1.59, 95% CI 1.36-1.84). The following factors decreased risk for DSPN: total cholesterol (OR 0.98, 95% CI 0.96-1.00) and exercise therapy (OR 0.85, 95% CI 0.73-0.98).</p><p><strong>Conclusions: </strong>The baseline survey clarified the prevalence and characteristics of DSPN in Japanese patients with type 2 diabetes. The survey also revealed the risk factors of DSPN.</p>","PeriodicalId":11340,"journal":{"name":"Diabetology International","volume":"15 1","pages":"19-27"},"PeriodicalIF":1.3,"publicationDate":"2024-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10800318/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139541853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-08DOI: 10.1007/s13340-023-00681-7
J. Oya, Tomoko Nakagami, Y. Hasegawa, Yuichiro Kondo, Akihiko Katamine, Mika Shimizu, Ryo Kubota, Rika Suda, T. Babazono
{"title":"Effectiveness of insulin degludec/liraglutide versus insulin degludec/insulin aspart in Japanese patients with type 2 diabetes","authors":"J. Oya, Tomoko Nakagami, Y. Hasegawa, Yuichiro Kondo, Akihiko Katamine, Mika Shimizu, Ryo Kubota, Rika Suda, T. Babazono","doi":"10.1007/s13340-023-00681-7","DOIUrl":"https://doi.org/10.1007/s13340-023-00681-7","url":null,"abstract":"","PeriodicalId":11340,"journal":{"name":"Diabetology International","volume":"11 10","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139446940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-08DOI: 10.1007/s13340-023-00684-4
Hae Hyuk Jung
{"title":"Glycemic control and dementia risk in patients aged above and below 75 years","authors":"Hae Hyuk Jung","doi":"10.1007/s13340-023-00684-4","DOIUrl":"https://doi.org/10.1007/s13340-023-00684-4","url":null,"abstract":"","PeriodicalId":11340,"journal":{"name":"Diabetology International","volume":"57 13","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139447241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-19DOI: 10.1007/s13340-023-00680-8
Tamsheel F. Roohi, S. Mehdi, Sadaf Aarfi, K. L. Krishna, Suman Pathak, Seikh Mohammad Suhail, Syed Faizan
{"title":"Biomarkers and signaling pathways of diabetic nephropathy and peripheral neuropathy: possible therapeutic intervention of rutin and quercetin","authors":"Tamsheel F. Roohi, S. Mehdi, Sadaf Aarfi, K. L. Krishna, Suman Pathak, Seikh Mohammad Suhail, Syed Faizan","doi":"10.1007/s13340-023-00680-8","DOIUrl":"https://doi.org/10.1007/s13340-023-00680-8","url":null,"abstract":"","PeriodicalId":11340,"journal":{"name":"Diabetology International","volume":" December","pages":""},"PeriodicalIF":2.2,"publicationDate":"2023-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138960480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-18DOI: 10.1007/s13340-023-00676-4
Masaji Sakaguchi
{"title":"Adipose Tissue Plasticity and Insulin Signaling in the Pathogenesis of Type 2 Diabetes","authors":"Masaji Sakaguchi","doi":"10.1007/s13340-023-00676-4","DOIUrl":"https://doi.org/10.1007/s13340-023-00676-4","url":null,"abstract":"","PeriodicalId":11340,"journal":{"name":"Diabetology International","volume":"139 4","pages":""},"PeriodicalIF":2.2,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138995392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-16DOI: 10.1007/s13340-023-00673-7
Shubham Ranjan, R. Thakur
{"title":"Gender differential in the pattern and severity of perceived symptoms among diabetes patients in India","authors":"Shubham Ranjan, R. Thakur","doi":"10.1007/s13340-023-00673-7","DOIUrl":"https://doi.org/10.1007/s13340-023-00673-7","url":null,"abstract":"","PeriodicalId":11340,"journal":{"name":"Diabetology International","volume":"34 9","pages":""},"PeriodicalIF":2.2,"publicationDate":"2023-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138967245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-12DOI: 10.1007/s13340-023-00685-3
Hiroshi Takahashi, Yuka Suganuma, Takayuki Ohno, R. Nishimura
{"title":"Correction: Trends in clinical characteristics and factors associated with initial prescription of SGLT2 inhibitors in Japanese patients with type 2 diabetes mellitus","authors":"Hiroshi Takahashi, Yuka Suganuma, Takayuki Ohno, R. Nishimura","doi":"10.1007/s13340-023-00685-3","DOIUrl":"https://doi.org/10.1007/s13340-023-00685-3","url":null,"abstract":"","PeriodicalId":11340,"journal":{"name":"Diabetology International","volume":"76 7","pages":""},"PeriodicalIF":2.2,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139008135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Influence of diet and body weight in treatment-resistant acquired partial lipodystrophy after hematopoietic stem cell transplantation and its potential for metabolic improvement","authors":"Emi Ishida, Kazuhiko Horiguchi, Shunichi Matsumoto, Atsushi Ozawa, Sho Sekiguchi, Eijiro Yamada","doi":"10.1007/s13340-023-00674-6","DOIUrl":"https://doi.org/10.1007/s13340-023-00674-6","url":null,"abstract":"","PeriodicalId":11340,"journal":{"name":"Diabetology International","volume":"12 5","pages":""},"PeriodicalIF":2.2,"publicationDate":"2023-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138979252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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