Pub Date : 2022-01-01DOI: 10.1358/dof.2022.47.9.3440036
B. G. Santani, B. Leblanc, R. Thakare
{"title":"Cefepime/taniborbactam. Fixed-dose combination, Cephalosporin beta-lactam antibiotic/beta-lactamase inhibitor, Treatment of complicated urinary tract infection","authors":"B. G. Santani, B. Leblanc, R. Thakare","doi":"10.1358/dof.2022.47.9.3440036","DOIUrl":"https://doi.org/10.1358/dof.2022.47.9.3440036","url":null,"abstract":"","PeriodicalId":11366,"journal":{"name":"Drugs of The Future","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66445538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.1358/dof.2022.47.5.3400574
R. Orlandi, A. Gajofatto
{"title":"Tolebrutinib. Bruton tyrosine kinase (BTK) inhibitor, Treatment of multiple sclerosis","authors":"R. Orlandi, A. Gajofatto","doi":"10.1358/dof.2022.47.5.3400574","DOIUrl":"https://doi.org/10.1358/dof.2022.47.5.3400574","url":null,"abstract":"","PeriodicalId":11366,"journal":{"name":"Drugs of The Future","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66444215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.1358/dof.2022.47.10.3487258
P. Sudha
{"title":"Alzheimer's Association International Conference (AAIC) 2022. San Diego - July 31-August 4, 2022","authors":"P. Sudha","doi":"10.1358/dof.2022.47.10.3487258","DOIUrl":"https://doi.org/10.1358/dof.2022.47.10.3487258","url":null,"abstract":"","PeriodicalId":11366,"journal":{"name":"Drugs of The Future","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66441054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.1358/dof.2022.47.11.3509748
L. Fernández Bertolín
{"title":"Pipeline on the Move - November 2022","authors":"L. Fernández Bertolín","doi":"10.1358/dof.2022.47.11.3509748","DOIUrl":"https://doi.org/10.1358/dof.2022.47.11.3509748","url":null,"abstract":"","PeriodicalId":11366,"journal":{"name":"Drugs of The Future","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66441670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.1358/dof.2022.47.2.3335977
C. Asadov, G. Aliyeva, A. Shirinova, Z. Alimirzoyeva
{"title":"Rationale of ferroportin inhibition for beta-thalassemia management","authors":"C. Asadov, G. Aliyeva, A. Shirinova, Z. Alimirzoyeva","doi":"10.1358/dof.2022.47.2.3335977","DOIUrl":"https://doi.org/10.1358/dof.2022.47.2.3335977","url":null,"abstract":"","PeriodicalId":11366,"journal":{"name":"Drugs of The Future","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66442317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.1358/dof.2022.47.3.3360407
M. Rickmann
{"title":"Relacorilant. Glucocorticoid receptor antagonist, Treatment of Cushing syndrome, Treatment of prostate cancer, Treatment of ovarian cancer","authors":"M. Rickmann","doi":"10.1358/dof.2022.47.3.3360407","DOIUrl":"https://doi.org/10.1358/dof.2022.47.3.3360407","url":null,"abstract":"","PeriodicalId":11366,"journal":{"name":"Drugs of The Future","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66443017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.1358/dof.2022.47.5.3433515
E. Cruces
{"title":"BIO-Europe Spring Digital 2022 - 16th Annual Partnering Conference. Virtual - March 28-31, 2022","authors":"E. Cruces","doi":"10.1358/dof.2022.47.5.3433515","DOIUrl":"https://doi.org/10.1358/dof.2022.47.5.3433515","url":null,"abstract":"","PeriodicalId":11366,"journal":{"name":"Drugs of The Future","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66443826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.1358/dof.2022.47.7.3447440
R. Bandari
{"title":"Association for Cancer Immunotherapy (CIMT) - 19th Annual Meeting. Mainz/Virtual - May 10-12, 2022","authors":"R. Bandari","doi":"10.1358/dof.2022.47.7.3447440","DOIUrl":"https://doi.org/10.1358/dof.2022.47.7.3447440","url":null,"abstract":"","PeriodicalId":11366,"journal":{"name":"Drugs of The Future","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66445196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.1358/dof.2022.47.1.3393242
D. Fernández-Forner
The Royal Chemistry Society/Society of Chemistry Industry (RSC/SCI) Medicinal Chemistry Symposium is a key symposium in the field of medicinal chemistry that takes place every 2 years at the University of Cambridge, U.K., under the auspices of the RSC and the SCI. This year, in its 21st edition, it was run as a hybrid event, simultaneously attended by both in-person and virtual attendees. Its theme was 'Improving Success', and 25 orals and 30 posters were presented. The scientific program covered recent medicinal chemistry achievements in major therapeutic areas, with a few first-time structure disclosure presentations and particular emphasis on emerging early-stage drug discovery and lead optimization strategies, including reports of successful case studies illustrating fragment-based screening and phenotypic target engagement approaches. Applications of artificial intelligence (AI), mass spectrometry and photochemistry in drug design and discovery were also highlighted. This report will cover some of the medicinal chemistry presentations delivered at the meeting.
{"title":"21st RSC/SCI Medicinal Chemistry Symposium. Cambridge/Virtual - September 13-15, 2021","authors":"D. Fernández-Forner","doi":"10.1358/dof.2022.47.1.3393242","DOIUrl":"https://doi.org/10.1358/dof.2022.47.1.3393242","url":null,"abstract":"The Royal Chemistry Society/Society of Chemistry Industry (RSC/SCI) Medicinal Chemistry Symposium is a key symposium in the field of medicinal chemistry that takes place every 2 years at the University of Cambridge, U.K., under the auspices of the RSC and the SCI. This year, in its 21st edition, it was run as a hybrid event, simultaneously attended by both in-person and virtual attendees. Its theme was 'Improving Success', and 25 orals and 30 posters were presented. The scientific program covered recent medicinal chemistry achievements in major therapeutic areas, with a few first-time structure disclosure presentations and particular emphasis on emerging early-stage drug discovery and lead optimization strategies, including reports of successful case studies illustrating fragment-based screening and phenotypic target engagement approaches. Applications of artificial intelligence (AI), mass spectrometry and photochemistry in drug design and discovery were also highlighted. This report will cover some of the medicinal chemistry presentations delivered at the meeting.","PeriodicalId":11366,"journal":{"name":"Drugs of The Future","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66440415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.1358/dof.2022.47.1.3393251
E. R. Domenech, P. Cole, X. Bofill
The 2021 AACR-NCI-EORTC Molecular Targets and Cancer Therapeutics meeting, organized by the European Organization for Research and Treatment of Cancer (EORTC), the National Cancer Institute (NCI) and the American Association for Cancer Research (AACR), was held in a virtual format due to the ongoing COVID-19 pandemic. Historically, 1,500 to 2,500 academics, scientists and pharmaceutical industry representatives come together at this meeting to deliver the latest updates on drug discovery, target selection, cellular and molecular biology, and early clinical trials. This year presentations were delivered both live and on-demand in oral and poster sessions. This report highlights some of the important research presented throughout the meeting.
{"title":"AACR-NCI-EORTC - 33rd International Symposium on Molecular Targets and Cancer Therapeutics. Virtual - October 7-10, 2021","authors":"E. R. Domenech, P. Cole, X. Bofill","doi":"10.1358/dof.2022.47.1.3393251","DOIUrl":"https://doi.org/10.1358/dof.2022.47.1.3393251","url":null,"abstract":"The 2021 AACR-NCI-EORTC Molecular Targets and Cancer Therapeutics meeting, organized by the European Organization for Research and Treatment of Cancer (EORTC), the National Cancer Institute (NCI) and the American Association for Cancer Research (AACR), was held in a virtual format due to the ongoing COVID-19 pandemic. Historically, 1,500 to 2,500 academics, scientists and pharmaceutical industry representatives come together at this meeting to deliver the latest updates on drug discovery, target selection, cellular and molecular biology, and early clinical trials. This year presentations were delivered both live and on-demand in oral and poster sessions. This report highlights some of the important research presented throughout the meeting.","PeriodicalId":11366,"journal":{"name":"Drugs of The Future","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66440470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}