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Awareness of childhood pneumonia in Benin City, Nigeria 尼日利亚贝宁市对儿童肺炎的认识
Q4 Medicine Pub Date : 2016-06-28 DOI: 10.4314/EAMJ.V93I5
D. Nwaneri, A. Sadoh, Bc Ogboghodo, O. Famuyiwa, C. Eregie, O. Oviawe
Background : Mortality from pneumonia can be prevented by prompt recognition of symptoms of pneumonia by caregivers at home and appropriate seeking for medical care in a health facility. Active participation in pneumonia control by caregivers is dependent on the extent to which the members of the community are aware of  features of pneumonia and recognising that the child needs medical attention. Objective : To document the knowledge of community members about pneumonia using traders (market women and men in a popular market in Benin City, Nigeria). Design : A descriptive cross-sectional study. Setting : Edaiken market, Benin City, Nigeria. Subjects : All traders, women and men in Edaiken market Benin City Nigeria. Results : Of the 1374 respondents, 1220(88.8%) about pneumonia. Of these 1220, 57.9% correctly identified that pneumonia affects the lungs and exposure to breeze was the risk factor of pneumonia (86.7% of respondents). Knowledge score for  pneumonia was generally low with most respondents 1140(93.5%) scoring < 10 (Poor); and 79(6.5%) had scores 10 – 14 (Fair). Only one person (0.1%) had a score ≥ 15 (Good knowledge). Married individuals were five times more likely to have fair knowledge of pneumonia when compared to the unmarried individuals (OR = 5.0, p = 0.01). Also statistical significant proportion of respondents with presence of an under-five year old in the household had fair knowledge of childhood pneumonia when compared with household with no child younger than five years (p = 0.00). Conclusion : General knowledge of the traders in Benin City about childhood pneumonia was poor. There is need for improved public awareness on childhood pneumonia in this community.
背景:家中护理人员及时识别肺炎症状,并在卫生机构适当寻求医疗护理,可预防肺炎死亡。护理人员对肺炎控制的积极参与取决于社区成员对肺炎特征的了解程度和认识到儿童需要医疗照顾的程度。目的:记录社区成员使用商贩(尼日利亚贝宁市一个热门市场的商贩男女)的肺炎知识。设计:描述性横断面研究。地点:尼日利亚贝宁市Edaiken市场研究对象:尼日利亚贝宁市Edaiken市场的所有商人,男女。结果:1374名应答者中,肺炎应答者1220人(88.8%)。在这1220人中,57.9%正确地识别出肺炎影响肺部,暴露在微风中是肺炎的危险因素(86.7%的受访者)。肺炎知识得分普遍较低,1140分(93.5%)得分< 10分(较差);得分10 ~ 14分(一般)的79个(6.5%)。只有1人(0.1%)得分≥15分(良好知识)。已婚人群对肺炎的了解程度是未婚人群的5倍(OR = 5.0, p = 0.01)。与没有5岁以下儿童的家庭相比,家庭中有5岁以下儿童的受访者对儿童肺炎的了解程度也有统计学意义(p = 0.00)。结论:贝宁市商贩对儿童肺炎的认知程度较差。有必要提高这个社区公众对儿童肺炎的认识。
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引用次数: 0
OCCURENCE OF PORPHYROMONAS GINGIVALIS AND AGGREGATIBACTER ACTINOMYCETEMCOMITANS IN SUBGINGIVAL PLAQUE AMONG PATIENTS WITH PERIODONTAL DISEASE AT THE UNIVERSITY OF NAIROBI DENTAL HOSPITAL 内罗毕大学牙科医院牙周病患者龈下菌斑中牙龈卟啉单胞菌和放线菌聚集菌的发生率
Q4 Medicine Pub Date : 2016-05-31 DOI: 10.4314/EAMJ.V93I4
Jethro J. C. Wambugu, N. Matu, T. Mulli, L. Gathece
Objectives: To determine the occurrence of Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans in patients with periodontal disease using polymerase Chain Reaction. Design: A descriptive cross-sectional study. Setting: The University of Nairobi Dental Hospital. Subjects: Patients presenting at the Oral Diagnosis and Periodontology clinics during the period of the study. The patients had periodontal examination done followed by subgingival plaque collection from selected teeth. DNA extraction from the plaque samples was then done followed by PCR based on Taqman probes using commercially available kits. Results: A total of 92 participants were recruited in the study. Aggregatibacter actinomycetemcomitans ( A.a ) was found in 14 (15.20%) while Porphyromonas gingivalis ( P.g ) was present in 16 (17.40%) of the study participants. Based on independent sample t-test, statistically significant positive associations were found between detection frequency of Porphyromonas gingivalis and plaque score (t= 2.47, p= 0.015), gingival index (t= 3.24, p= 0.022), but not with clinical attachment loss (t= 1.90, p= 0.061). Chi square test revealed a positive association between detection rate of P.g and periodontal disease severity (X 2 = 6.34, p= 0.042). Similar association was also found between detection rate of Aggregatibacter actinomycetemcomitans and increasing age (t=2.19, p= 0.031), clinical attachment loss (t= 4.61, p<0.001) and periodontal disease severity (X 2 =11.23, p= 0.004). Conclusion: The multiplex polymerase chain reaction technique utilised in this study enabled detection of target bacteria in the same reaction mixture as opposed to other periodontal microbiological techniques that require each bacteria to be investigated individually therefore PCR should be considered as an alternative to other methods of periodontal microbiology investigation. The association between periopathogenic microorganisms, A.a and P.g with occurrence and severity of periodontal disease were also confirmed in this study.
目的:应用聚合酶链反应测定牙周病患者牙龈卟啉单胞菌和放线菌聚集菌的发生情况。设计:描述性横断面研究。环境:内罗毕大学牙科医院。研究对象:研究期间在口腔诊断和牙周病诊所就诊的患者。患者进行牙周检查,然后从选定的牙齿上收集龈下菌斑。然后从斑块样本中提取DNA,然后使用市售试剂盒进行基于Taqman探针的PCR。结果:研究共招募了92名参与者。在14例(15.20%)研究参与者中发现放线菌聚集菌(A.a),而在16例(17.40%)研究参与者中发现牙龈卟啉单胞菌(P.g)。经独立样本t检验,牙龈卟啉单胞菌检出率与菌斑评分(t= 2.47, p= 0.015)、牙龈指数(t= 3.24, p= 0.022)呈正相关,与临床附着丧失无显著正相关(t= 1.90, p= 0.061)。卡方检验显示P.g检出率与牙周病严重程度呈正相关(x2 = 6.34, p= 0.042)。放线菌聚集杆菌的检出率与年龄增长(t=2.19, p= 0.031)、临床附着丧失(t= 4.61, p<0.001)和牙周病严重程度(x2 =11.23, p= 0.004)也存在类似的相关性。结论:本研究中使用的多重聚合酶链反应技术能够在相同的反应混合物中检测目标细菌,而不是其他牙周微生物学技术,需要单独调查每种细菌,因此PCR应被视为其他牙周微生物学调查方法的替代方法。本研究也证实了牙周病微生物、A.a和P.g与牙周病的发生和严重程度之间的关系。
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引用次数: 0
A national survey of oxytocin use during caesarean section in Zimbabwe 津巴布韦剖宫产术中催产素使用的全国调查
Q4 Medicine Pub Date : 2016-03-11 DOI: 10.4314/EAMJ.V93I1
F. Madzimbamuto, E. Chikumba, H. Lonnée, L. Kashiri, NS Dube, S. Shumbairerwa
Background: Post-partum haemorrhage is the leading cause of mortality for labouring women in Zimbabwe. Current literature supports the use of low dose oxytocin to prevent bleeding during Caesarean section. Internationally, clinical practice has been slow to change and the use of potentially harmful, higher than recommended dose is common. Objective: To describe the current clinical practice in Zimbabwe. Design: A self-administered questionnaire survey. Descriptive statistics were used to report the study results. Setting: In 2013 a national survey was conducted on the use of oxytocin by different types of clinicians, who provide either anaesthesia or surgery for Caesarean section. Results: Of a total of 221 (61%) questionnaires returned, 170 (80%) were completed fully. Only 23% of respondents would give an intravenous dose of 5.0 IU or less of oxytocin for elective Caesarean section. The majority of clinicians (77%) would administer more than 5.0 IU of oxytocin at elective. A significant number of nurse anaesthetists 16/59 (27%), and a non-negligible number of specialist anaesthetists 3/48 (6%) would even give 20 IU of oxytocin in elective cases rising to 30% and 13% respectively for emergency cases. In case of persistent bleeding due to uterine atony, oxytocin was more likely to be repeated (45%), rather than using misoprostol (25%) or ergometrine (19%). Conclusion: Most clinicians in Zimbabwe use oxytocin doses well above current internationally recommended. This illustrates the urgent need for updated national guidelines for the prevention of post-partum haemorrhage during Caesarean section.
背景:产后出血是津巴布韦劳动妇女死亡的主要原因。目前的文献支持使用低剂量催产素预防剖宫产出血。在国际上,临床实践变化缓慢,使用可能有害的、高于推荐剂量的剂量很常见。目的:描述目前在津巴布韦的临床实践。设计:自我管理的问卷调查。采用描述性统计方法报道研究结果。背景:2013年,一项关于不同类型的临床医生使用催产素的全国性调查进行了,这些临床医生为剖宫产提供麻醉或手术。结果:共发放问卷221份(61%),完整填写170份(80%)。只有23%的应答者会在择期剖宫产时给予静脉注射5.0 IU或更少的催产素。大多数临床医生(77%)会选择性地给予超过5.0 IU的催产素。相当数量的护士麻醉师16/59(27%)和不可忽略的专科麻醉师3/48(6%)甚至会在选择性病例中给予20 IU的催产素,分别上升到30%和13%的急诊病例。对于由于子宫张力引起的持续出血,重复使用催产素的可能性更大(45%),而不是使用米索前列醇(25%)或麦角新碱(19%)。结论:津巴布韦大多数临床医生使用的催产素剂量远高于目前国际推荐的剂量。这说明迫切需要更新预防剖腹产期间产后出血的国家指南。
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引用次数: 1
Ogilvie’s syndrome: case report of spontaneous rupture of the ceacum following caesarean section 奥吉维氏综合征:剖宫产术后自发性空腔破裂1例
Q4 Medicine Pub Date : 2016-01-01 DOI: 10.4314/EAMJ.V93I12
Omondi-Ogutu Omondi-Ogutu, J. Adwok, N. Nganga, E. Rogena, P. Olang
Objective: To provide data on nutritional status and risk factors affecting the population aged 45 years and above for health policy development and program planning.Design: A cross sectional studySetting: Dagoretti sub-County of Nairobi County.Subjects: Two hundred and eighty nine (289) purposefully selected households (29.8%males and 70.2%females) aged 45 years and above.Main outcome measures: Quantitative household data were collected using a semistructured questionnaire. In-depth interviews and focus group discussions were used to collect qualitative data. Information on selected demographic and socio-economic household characteristics, health and food security was documented. Nutritional status was assessed using body mass index (BMI) and mid-upper arm circumference (MUAC).Results: The study established that majority of this population faced many nutrition risks including lack of access to finances 161(58.5%), ill health 70(25.5%), rejection by community and relatives 26(9.5%) and taking care of grandchildren 10(3.6%) abandoned or orphaned by HIV/AIDS. Malnutrition using MUAC was 18.8% while by BMI was 11.4%. Of the population assessed, 46.4% had normal nutritional status while 40.9% were overweight, and 12.7% underweight, with more females (48.0%) than males (25.9%) being overweight.Conclusion: Under nutrition and obesity are problems facing this population group aged 45 years and above in Nairobi. There is need for policy makers and programme managers to develop interventions aimed at minimising the effects of risks faced by this population in order to improve their well being.
急性结肠假性梗阻(ACPO)表现为无器质性障碍的结肠扩张(内源性或外源性肠壁障碍)。这就成为了一个可能导致病人死亡的终极狂喜的潜在场所。本文报告一位母亲在剖宫产后5天发生自发性盲肠狂喜的病例。在剖腹手术中证实了腹腔破裂,并进行了结肠造口术。术后2天患者在重症监护病房死亡。
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引用次数: 2
Spatial distribution and habitat characterisation of mosquito species in the lake and land habitats of western Kenya 肯尼亚西部湖泊和陆地生境蚊种空间分布及生境特征
Q4 Medicine Pub Date : 2016-01-01 DOI: 10.4314/EAMJ.V93I3
S. Adoka, G. Dida, D. Anyona, A. Matano, D. Othero, C. Kanangire
Background : Infections with mosquito-borne parasites are common in human populations inhabiting tropical regions of the world. Malaria is endemic along Kenyan Lake Victoria basin and its vectors are fresh water breeders. However, much less is known about the current spatial distribution and habitat characterisation of mosquitoes including vectors of malaria in the lake waters and adjacent terrestrial aquatic habitats. Objectives : To characterise mosquito larval habitats and to determine the spatial distribution of mosquito species in lake and land habitats, measure aquatic habitats’ (water) physic-chemical parameters, enumerate the number of phytoplankton, zooplankton and fish species and determine their effects on the abundance of mosquitoes. This could allow larval control to be more effectively targeted at specific sites which in its turn could reduce malaria transmission in the area. Design : Cross-sectional study. Setting : The Kenyan Lake Victoria Basin. Results : Anopheles and Culex species of mosquitoes were absent in different locations in the lake, but abundant in different aquatic habitats in different locations on land. There was heterogeneity in the relative abundance of Anopheles and Culex species in the aquatic habitats in different locations on land, p 0.05 (Pearsons correlation coefficiency). Also, there was no significant correlation between abundance of Anopheles mosquitoes and phytoplanktons, (P>0.05). Significant correlation was however, observed with Dinoflagellates on land, P=0.014.  Clarias gariepinus were more insectivorous compared to Oreochromis niloticus , which mostly fed on zooplankton and food remains. The most abundant mosquitoes in the lake were Mansonia followed by Aedes species of mosquitoes. Conclusion : Anopheles species of mosquitoes do not breed in deep permanent lake waters even if it is heavily infested by water hyacinth and other aquatic weeds. However, they breed in temporary or seasonal aquatic land habitats such as pools and swamps, more so when infested by aquatic and other vegetations. We recommend that, focus of malaria vector control should concentrate on land sites. Health education and awareness programs should be scaled up to inform the local communities on mosquito species ecology in relation to transmission of malaria and other mosquito- borne diseases. There is need to introduce certain fish species ( Clarias gariepinus ) for biological control of mosquitoes breeding in the aquatic habitats near human habitats.
背景:蚊媒寄生虫感染在生活在世界热带地区的人群中很常见。疟疾沿肯尼亚维多利亚湖盆地流行,其病媒是淡水繁殖者。然而,目前对湖泊水域和邻近陆生水生生境中包括疟疾媒介在内的蚊子的空间分布和生境特征知之甚少。目的:研究蚊幼虫栖息地特征,确定湖泊和陆地生境蚊种空间分布,测定水生生境(水)理化参数,枚举浮游植物、浮游动物和鱼类种类数量,确定其对蚊类丰度的影响。这可以使幼虫控制更有效地针对特定地点,这反过来又可以减少该地区的疟疾传播。设计:横断面研究。环境:肯尼亚维多利亚湖盆地。结果:湖上不同地点蚊种均为按蚊和库蚊,陆地上不同地点的不同水生生境蚊种均较多。陆地不同地点水生生境中按蚊和库蚊的相对丰度存在异质性,pearson相关系数p < 0.05。按蚊的丰度与浮游植物的丰度无显著相关(P < 0.05)。与陆地上的鞭毛藻有显著的相关性,P=0.014。与主要以浮游动物和食物残渣为食的nilochromis相比,Clarias gariepinus更倾向于食虫。湖中蚊种最多的是曼蚊,其次是伊蚊。结论:在深固湖水体中,即使被水葫芦等水草严重侵染,按蚊类也不能孳生。然而,它们在池塘和沼泽等临时或季节性的水生陆地栖息地繁殖,当被水生植物和其他植物侵染时更是如此。我们建议,疟疾病媒控制的重点应集中在陆地上。应扩大健康教育和宣传计划,向当地社区通报与疟疾和其他蚊媒疾病传播有关的蚊子物种生态学。有必要引进某些鱼类(如gariepinclarias gariepinus),以生物防治蚊虫在人类生境附近的水生生境孳生。
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引用次数: 1
Premature ovarian failure in twins: case report 双胞胎卵巢早衰1例报告
Q4 Medicine Pub Date : 2016-01-01 DOI: 10.4314/EAMJ.V93I6
J. Wanyoike-Gichuhi, R. Parkar, B. Kihara, D. Ondieki
Premature ovarian failure (POF)is a serious life-changing condition that affects young women, remains an enigma and the researchers’ challenge. POF, premature ovarian insufficiency (POI), premature menopause, premature dysfunction (POD), or hypergonadotropic hypogonadism is one of the most perplexing disorders with aheterogeneous origin. Infertility, social and psychological stress are common consequences of this entity. This paper presents a rare condition where both twins had presented with POF.
卵巢早衰(POF)是影响年轻女性的一种严重的改变生活的疾病,仍然是一个谜,也是研究人员面临的挑战。POF,卵巢功能不全(POI),过早绝经,过早功能障碍(POD),或促性腺功能低下是最复杂的疾病之一,具有异质起源。不育,社会和心理压力是这种实体的常见后果。这篇论文提出了一个罕见的条件,双胞胎都提出了POF。
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引用次数: 0
Endometriosis in unicornuate uterus with non-communicating rudimentary horn 单角形子宫的子宫内膜异位症
Q4 Medicine Pub Date : 2015-12-09 DOI: 10.4314/EAMJ.V92I10
J. Gichuhi, R. Parkar, D. Ondieki
Endometriosis, defined as the presence of endometrial tissue outside the uterine cavity, is itself an enigmatic  and multifaceted pathology, a puzzle whose manifold piece remain largely disconnected despite some decades  of investigation. Its medical history and clinical presentation is heterogeneous. Endometriosis affects  approximately 10% of women of reproductive age, given its high prevalence and that women with endometriosis may have severe pelvic pain and infertility, endometriosis poses a significant health problem.  Evaluating and understanding the pathogenesis, clinical presentation, diagnosis of the endometriosis is critical  in the management of this debilitating disease. A rare case of endometriosis in a patient with congenital  anomaly-Unicornuate uterus with one unconnected rudimentary horn is presented.
子宫内膜异位症被定义为子宫腔外存在子宫内膜组织,它本身就是一个谜,是一个多方面的病理,尽管几十年的研究,其多方面的部分仍然在很大程度上没有联系。其病史和临床表现各不相同。子宫内膜异位症影响约10%的育龄妇女,鉴于其高患病率,并且患有子宫内膜异位症的妇女可能患有严重的盆腔疼痛和不孕症,子宫内膜异位症造成了严重的健康问题。评估和了解子宫内膜异位症的发病机制、临床表现和诊断对治疗这种使人衰弱的疾病至关重要。一个罕见的病例子宫内膜异位症患者先天性异常-独角状子宫与一个未连接的基本角提出。
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引用次数: 2
SCALING UP NON-COMMUNICABLE DISEASE CONTROL: LESSONS TO BE LEARNT FROM THE INFECTIOUS DISEASE PARADIGM IN KENYA. 加强非传染性疾病控制:从肯尼亚传染病范例汲取的经验教训。
Q4 Medicine Pub Date : 2015-12-01
A Njoroge, K E Munene

Non-communicable diseases (NCD) are emerging as the leading cause of morbidity & mortality globally, with the greatest rise in incidence of cardiovascular disease cases observed in Sub-Saharan Africa. This is in addition to the heavy burden of infectious diseases already present in this setting. Describing the cross-cutting epidemiology of NCDs and infectious diseases with focus on the interaction between tuberculosis and diabetes mellitus, HIV and cardiovascular disease, HIV and cervical cancer as well as assessing the disparities in funding and service delivery systems between NCDs and infectious diseases; we review this rising double burden of infectious and non-infectious diseases and propose four lessons that can be learnt from the HIV response and adapted to inform the scale up of NCD control in Kenya which are also applicable in other African countries.

非传染性疾病正在成为全球发病率和死亡率的主要原因,撒哈拉以南非洲的心血管疾病发病率上升幅度最大。这是在这种情况下已经存在的传染病的沉重负担之外发生的。描述非传染性疾病和传染病的交叉流行病学,重点是结核病和糖尿病、艾滋病毒和心血管疾病、艾滋病毒和宫颈癌之间的相互作用,以及评估非传染性疾病和传染病之间在资金和服务提供系统方面的差异;我们审查了传染病和非传染病这一不断上升的双重负担,并提出了可以从艾滋病毒应对中吸取的四条经验教训,并加以调整,为肯尼亚扩大非传染性疾病控制提供信息,这些教训也适用于其他非洲国家。
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引用次数: 0
Uterine Rupture in a Primigravida with Mullerian Anomaly at 27 Weeks Gestation 妊娠27周伴有缪勒管异常的初产妇子宫破裂
Q4 Medicine Pub Date : 2015-10-01 DOI: 10.4314/EAMJ.V92I5
K. Kunuthia, A. Kihara, RJ Kosgei, AN Bosire
Mullerian anomalies are rare and are often associated with infertility, chronic pelvic pain and pregnancy  wastage. This is a case report of a primigravida at 27 weeks gestation, who presented in shock. Intra- operatively, a mullerian anomaly with a ruptured left horn was found and excised. She made remarkable  recovery and was discharged home. Uterine anomalies should be ruled out in the evaluation of pregnancy  wastage. When present, management should be individualized based on the clinical history, presentation, anatomical aberration and the patient’s future fertility desire.
苗勒管异常是罕见的,通常与不孕,慢性盆腔疼痛和妊娠浪费有关。这是一个病例报告初产妇在妊娠27周,谁提出了休克。术中发现一例伴有左角破裂的苗勒管畸形并切除。她恢复得很好,出院回家了。在评估妊娠浪费时应排除子宫异常。当出现时,应根据临床病史、表现、解剖畸变和患者未来的生育愿望进行个体化治疗。
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引用次数: 3
Dual omental flap in obliterating post-pneumonectomy bronchopleural fistulae 双网膜瓣在肺切除术后支气管胸膜瘘封堵中的应用
Q4 Medicine Pub Date : 2015-06-01 DOI: 10.4314/EAMJ.V92I7
HI Magale, I. Kassim, S. Odera, MJ Omolo, W. Jaoko, P. E. Jolly
Background : Post-pneumonectomy bronchopleural fistulae is associated with high mortality and  morbidity. The omental flap has been widely used to manage this condition either through laparoscopic or open surgery with varied degrees of success. We present a modification of the omental flap by using two flaps of the omentum in obliterating the bronchopleural fistulae. Objective : To evaluate the effectiveness of dual omental flap in obliteration of postpneumonectomy bronchopleural fistulae D esign: A prospective clinical study. Setting : The cardiothoracic unit at the Kenyatta National Hospital between January 2010 and December 2013 . Subjects : Five patients with post-pneumonectomy bronchopleural fistulae managed in a period of four years. Results : Pneumonectomy were due to cancer of the lungs in two patients and tuberculosis in three  patients. All the patients had previously attempted repair with a pleural patch without success. Dual omental flap was utilised to repair the fistulae. All patients had successful repair of the fistula and no recurrence was noted at one year of follow up. Conclusion : Dual omental flap offers an alternative technique in obliterating postpneumonectomy fistula. The two flap technique allows for one flap to completely seal the fistula while the second flap provides an additional airtight closure over the first flap and hence prevents any leakages. This ensures higher success rate with few recurrences.
背景:肺切除术后支气管胸膜瘘死亡率和发病率高。网膜瓣已被广泛用于通过腹腔镜或开放手术治疗这种疾病,并取得了不同程度的成功。我们提出了一种网膜瓣的修改,使用两个网膜瓣来消除支气管胸膜瘘。目的:探讨双网膜瓣在肺切除术后支气管胸膜瘘封堵中的应用价值。背景:2010年1月至2013年12月,肯雅塔国立医院心胸科。研究对象:对5例肺切除术后支气管胸膜瘘患者进行了4年的治疗。结果:2例因肺癌切除全肺,3例因肺结核切除全肺。所有患者之前都曾尝试胸膜贴片修复,但均未成功。采用双网膜瓣修复瘘管。所有患者都成功修复了瘘管,随访一年无复发。结论:双网膜瓣是消除肺切除术后瘘管的一种新方法。双瓣技术允许一个瓣完全密封瘘管,而第二个瓣在第一个瓣的基础上提供额外的密封,从而防止任何泄漏。这确保了更高的成功率和更少的重复。
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引用次数: 15
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East African medical journal
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