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Preventing bacterial diseases in dairy cattle 预防奶牛细菌性疾病
Pub Date : 2021-07-20 DOI: 10.19103/as.2020.0086.16
S. Aly, Sarah Depenbrock
A paradigm shift in the management of bacterial diseases of food animals is needed; a shift from pharmacologic interventions to disease risk identification and mitigation. The interaction between disease and its risk factors follows the disease triangle, a conceptual model that incorporates host, pathogen, and environmental factors as a tool to understand different aspects that influence disease. A sustainable approach to bacterial disease mitigation in production settings includes a comprehensive assessment of host, pathogen, and environmental factors of disease to build a prevention platform for multiple syndromes of bacterial disease in cattle. Using bovine respiratory disease as a model, the current chapter will focus on the state of the art of disease prevention in dairy cattle, and investigations into interactions between the host, environment and pathogen which can provide robust information on which to build a prevention platform for multiple syndromes of bacterial disease in cattle.
需要转变管理食用动物细菌性疾病的模式;从药物干预转向疾病风险识别和减轻。疾病及其危险因素之间的相互作用遵循疾病三角理论,这是一个概念模型,将宿主、病原体和环境因素纳入其中,作为理解影响疾病的不同方面的工具。在生产环境中减轻细菌性疾病的可持续方法包括对疾病的宿主、病原体和环境因素进行综合评估,以建立一个预防牛多种细菌性疾病综合征的平台。以牛呼吸道疾病为模型,本章将重点介绍奶牛疾病预防的最新进展,并研究宿主、环境和病原体之间的相互作用,为建立牛多种细菌性疾病的预防平台提供可靠的信息。
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引用次数: 0
Key issues in dairy herd health management 奶牛群健康管理中的关键问题
Pub Date : 2021-07-20 DOI: 10.19103/as.2020.0086.01
J. Remnant, J. Breen, P. Down, C. Hudson, Martin I. Green
Dairy herd health management benefits dairy farmers, the environment, dairy cows and citizens. It is an important part of modern dairy farm veterinary care. Dairy herd health management is assessing, monitoring and improving the health of dairy cows at a population level. Good herd health management takes a holistic approach and is ongoing and cyclical. All members of the dairy farm team and their advisors are involved, decisions are informed by data generated by the herd. These data may come from numerous sources. The data are processed and analysed to monitor cow health, target investigations and evaluate progress. To make lasting change on farms, advisors must communicate appropriately with farm managers to understand behaviour and motivate change. This chapter reviews these aspects of dairy herd health management, giving practical suggestions on how to get started, how to incorporate herd health management into business models and how to maintain momentum.
奶牛群健康管理有利于奶农、环境、奶牛和市民。是现代奶牛场兽医护理的重要组成部分。奶牛群健康管理是在种群水平上评估、监测和改善奶牛的健康。良好的畜群健康管理采取整体方法,是持续的和周期性的。奶牛场团队的所有成员和他们的顾问都参与其中,决策是根据牛群产生的数据做出的。这些数据可能来自许多来源。对这些数据进行处理和分析,以监测奶牛健康、确定调查目标并评估进展。为了在农场上做出持久的改变,顾问必须与农场经理进行适当的沟通,以了解行为并激励变革。本章回顾了奶牛群健康管理的这些方面,就如何开始,如何将奶牛群健康管理纳入商业模式以及如何保持势头给出了实用的建议。
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引用次数: 0
Advances in understanding immune response in dairy cattle 奶牛免疫反应的研究进展
Pub Date : 2021-07-20 DOI: 10.19103/as.2020.0086.06
B. Mallard, M. Emam, S. Cartwright, T. Altvater-Hughes, Alexandra M. Livernois, Lauri Wagter-Lesperance, D. Hodgins, H. Atalla, B. Hine, J. Aleri, A. Fisher
From the beginning, cattle have made important contributions to the field of immunology, including the development of the first Mycobacterium bovis BCG vaccine for human tuberculosis in 1921. In 1981 the first report of a biosynthesized polypeptide vaccine against Foot and Mouth Disease Virus (FMDV) using the VP3 protein expressed in Escherichia coli (E. coli) was made for cattle. Cattle also possess a substantial proportion of T cells expressing the γδ T-cell receptor which helped to elucidate the role of these unique cells in host defence. More recently, it was discovered that cattle produce antibodies with ultra-long Complementarity Determining Region (CDR) - 3. This seminal finding has allowed the production of bovine therapeutic broadly neutralizing antibodies with ultra-long CDRs to passively treat various virial infections in humans and play a key role in protecting cattle. This chapter will review advances in bovine immunology, particularly as it relates to dairy cattle.
从一开始,牛就对免疫学领域作出了重要贡献,包括在1921年研制出第一种用于治疗人类结核病的牛分枝杆菌卡介苗。1981年,利用大肠杆菌(E. coli)中表达的VP3蛋白,首次报道了用于牛的口蹄疫病毒(FMDV)生物合成多肽疫苗。牛还具有相当比例的表达γδ T细胞受体的T细胞,这有助于阐明这些独特细胞在宿主防御中的作用。最近,人们发现牛能产生具有超长互补决定区(CDR) - 3的抗体。这一开创性的发现使得生产具有超长cdr的牛治疗性广泛中和抗体能够被动治疗人类的各种病毒感染,并在保护牛方面发挥关键作用。本章将回顾牛免疫学的进展,特别是与奶牛有关的进展。
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引用次数: 0
Managing replacement and culling in dairy herds 管理奶牛群的替换和扑杀
Pub Date : 2021-07-20 DOI: 10.19103/as.2020.0086.12
A. De Vries
Approximately one third of dairy cows are replaced every year. Replacement of dairy cattle is an important part of the cost of dairy production and an environmental sustainability concern. Primary culling reasons are reduced health and fertility. Reduced welfare often proceeds culling. This chapter focuses on factors that affect replacement and culling in dairy herds with a focus on cows. The act of culling is simple, but the risk factors and economic considerations are complex. The chapter first presents some data on culling risks and reasons, explores more in depth the effects of poor health on culling, and presents aspects of economic decision making regarding culling and replacement decisions.
每年大约有三分之一的奶牛被替换。更换奶牛是乳品生产成本的重要组成部分,也是环境可持续性问题。扑杀的主要原因是健康和生育率下降。福利减少往往会导致淘汰。本章主要讨论影响奶牛替代和淘汰的因素。扑杀行动很简单,但风险因素和经济考虑是复杂的。本章首先介绍了一些关于扑杀风险和原因的数据,更深入地探讨了健康状况不佳对扑杀的影响,并介绍了有关扑杀和替换决策的经济决策方面。
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引用次数: 0
Managing calves/youngstock to optimise dairy herd health 管理小牛/幼牛以优化奶牛群的健康
Pub Date : 2021-07-20 DOI: 10.19103/as.2020.0086.11
J. Mee
This chapter demonstrates that youngstock management can play a critical role in optimising dairy herd health. While the immediate impact of better calf management is visible to farmers in better youngstock health and growth, the long-term benefits in dairy herd productivity and survival need to be emphasised more by veterinarians and agricultural advisers. The most consistently reported management factors associated with reduced age at first calving (AFC), higher milk production and longer survival were feeding a larger volume of colostrum, offering a higher liquid feed volume preweaning, offering a higher solids milk replacer, offering whole milk and a higher average daily gain. The three health disorders most frequently associated with increased AFC, lower milk production and shorter survival were dystocia, calf diarrhoea and respiratory disease. These results have implications for producer perception and management of calfhood nutrition and health hazards and veterinary communication on calfhood disease sequelae with lag dynamics.
本章证明了幼畜管理可以在优化奶牛群健康方面发挥关键作用。虽然对农民来说,更好的小牛管理的直接影响是更好的幼牛健康和生长,但兽医和农业顾问需要更多地强调奶牛群生产力和生存的长期效益。与降低初产犊龄(AFC)、提高产奶量和延长生存期相关的最一致的管理因素是饲喂大量初乳、在断奶前提供更高的液体饲料量、提供更高的固体乳替代品、提供全脂牛奶和更高的平均日增重。与AFC增加、产奶量减少和生存期缩短最常相关的三种健康疾病是难产、小牛腹泻和呼吸道疾病。这些结果对生产者对犊牛营养和健康危害的认知和管理以及兽医对犊牛疾病后遗症的滞后动态沟通具有重要意义。
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引用次数: 1
Optimizing udder health in dairy cattle 优化奶牛的乳房健康
Pub Date : 2021-07-20 DOI: 10.19103/as.2020.0086.13
T. Lam, S. De Vliegher
In this chapter several aspects of udder health are discussed. Mastitis, inflammation of the mammary gland, which is generally caused by bacterial infections, is one of the most important and most studied diseases in dairy cattle. Diagnostic approaches are discussed with specific attention for the bacteriological causes of the disease. Subsequently immunological aspects of intramammary infections will be reviewed. Because treatment of mastitis in unavoidable at some point in time in most dairy herds, attention is given to treatment of mastitis with an emphasis on different types of antibiotics and antibiotic resistance. The most important part of udder health management, however, is the preventive management. From that perspective, breeding, housing and nutrition are shortly discussed, as are the milking machine and milking procedures. Finally attention is given to problem solving once mastitis has led to a herd level problem and some future trends are discussed.
本章讨论了乳腺健康的几个方面。乳腺炎是一种乳腺炎症,通常由细菌感染引起,是奶牛最重要和研究最多的疾病之一。讨论了诊断方法,特别注意疾病的细菌学原因。随后将审查乳腺内感染的免疫学方面。由于在大多数奶牛群中,乳腺炎的治疗在某些时间点是不可避免的,因此应注意乳腺炎的治疗,重点是不同类型的抗生素和抗生素耐药性。然而,乳房健康管理最重要的部分是预防性管理。从这个角度来看,育种、住房和营养,以及挤奶机和挤奶程序都将很快讨论。最后,当乳腺炎发展为群体性问题时,应注意如何解决问题,并讨论未来的发展趋势。
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引用次数: 0
Advances in techniques for health monitoring/disease detection in dairy cattle 奶牛健康监测/疾病检测技术的进展
Pub Date : 2021-07-20 DOI: 10.19103/as.2020.0086.04
M. Iwersen, M. Drillich
Livestock production has been characterized by the intensification and specialization of production leading to larger farms and, hence, to fewer farmers per animal. Thus, the animal-to-stockman ratio is increasing and the available time for monitoring an individual animal is reducing. In the same time period, the focus in the veterinary profession has shifted from treatment of acutely diseased animals to more proactive management, which includes the use of epidemiological tools to identify risk factors for animal health, welfare and production. As part of a modern herd management, reliable data on animal health are provided e.g. by routine and standardized testing of animals for the presence of disease. For this, traditional and increasingly sophisticated diagnostic tools are available. Recently, farmers have increasingly been using sensor technologies, allowing continuous and automated health monitoring of livestock. This aims in establishing an early warning system to optimize herd health management and fostering decision making.
畜牧业生产的特点是生产的集约化和专业化,导致农场规模更大,因此每头牲畜的农民数量更少。因此,动物与牲畜的比例正在增加,监测单个动物的可用时间正在减少。在同一时期,兽医专业的重点已从治疗急性患病动物转向更积极主动的管理,其中包括使用流行病学工具来确定影响动物健康、福利和生产的风险因素。作为现代畜群管理的一部分,提供了可靠的动物健康数据,例如通过对动物进行常规和标准化的疾病检测。为此,传统的和日益复杂的诊断工具是可用的。最近,农民越来越多地使用传感器技术,允许对牲畜进行连续和自动化的健康监测。其目的是建立早期预警系统,以优化畜群健康管理和促进决策。
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引用次数: 1
Dairy cattle welfare and health: an intimate partnership 奶牛福利与健康:亲密的伙伴关系
Pub Date : 2021-07-20 DOI: 10.19103/as.2020.0086.08
C. Phillips
This chapter discusses the intimate partnership between dairy cattle welfare and health. It begins by examining the welfare implications of common dairy cow diseases such as lameness, mastitis, metritis, acidosis, ketosis and other production-related diseases. It also addresses the impact of subclinical diseases as well. Stress and immune function is also discussed, followed by a review of how mental health can impact the welfare of dairy cattle. A case study on the health and welfare of cows in Indian shelters is also included.
本章讨论奶牛福利与健康之间的密切关系。它首先检查了常见奶牛疾病的福利影响,如跛行、乳腺炎、子宫炎、酸中毒、酮症和其他与生产有关的疾病。它也解决了亚临床疾病的影响。还讨论了压力和免疫功能,随后回顾了心理健康如何影响奶牛的福利。还包括一个关于印度收容所奶牛健康和福利的案例研究。
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引用次数: 0
Managing dry cow udder health 管理奶牛的乳房健康
Pub Date : 2021-07-20 DOI: 10.19103/as.2020.0086.10
P. Rajala-Schultz, T. Halasa
The dry period lays a foundation for a successful next lactation, especially from the udder health perspective. It is a high-risk period for acquiring new intramammary infections (IMI), but it also provides an excellent opportunity for eliminating existing subclinical infections. The way cows are dried off and milking is halted at the end of lactation impacts the involution process, mammary health and cow comfort. Antibiotic dry cow therapy (DCT) has played a crucial part in mastitis control, but due to global concerns about increasing antibiotic resistance, the approach to DCT is evolving. This chapter reviews the current knowledge about the impact of milk cessation methods (abrupt vs. gradual dry-off) on mammary involution, udder health and cow comfort. The importance of dry cow therapy is discussed, especially in the light of current global concerns related to antibiotic resistance.
干燥期为下一次泌乳的成功奠定了基础,特别是从乳房健康的角度来看。这是获得新的乳腺内感染(IMI)的高风险时期,但它也提供了消除现有亚临床感染的绝佳机会。奶牛在哺乳期结束时被晒干并停止挤奶的方式影响了复归过程、乳腺健康和奶牛的舒适度。抗生素干牛疗法(DCT)在乳腺炎控制中起着至关重要的作用,但由于全球对抗生素耐药性增加的担忧,DCT的方法正在发展。本章回顾了目前关于停乳方法(突然与逐渐停乳)对乳房复旧、乳房健康和奶牛舒适度的影响的知识。讨论了干牛治疗的重要性,特别是在当前全球关注的抗生素耐药性的情况下。
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引用次数: 0
Key issues and challenges in disease surveillance in dairy cattle 奶牛疾病监测中的关键问题和挑战
Pub Date : 2021-07-20 DOI: 10.19103/as.2020.0086.03
L. Hernández-Castellano, K. Ingvartsen, M. Krogh
This chapter provides an overview on the different aspects concerning disease surveillance programs. The chapter also describes a specific and conceptual framework related to disease surveillance of production diseases within the individual herd, including both animals and farmers. Regarding farmers, this chapter focus on the justification and purposes for doing disease surveillance as well as the possible decisions and actions they can take to enhance the efficiency of the disease surveillance programs. It also discusses some of the most novel biomarkers that can be potentially used to identify pre-clinical disease states, which will have the potential to minimize the negative effects of production diseases. Finally, the chapter looks into the future perspectives and possible challenges that future automated disease surveillance systems will need to face in order to keep an optimal animal health, performance and welfare within the individual herd.
本章概述了疾病监测项目的不同方面。本章还描述了与个体畜群(包括动物和农民)内生产疾病的疾病监测有关的具体和概念性框架。关于农民,本章重点讨论了进行疾病监测的理由和目的,以及他们可以采取的决策和行动,以提高疾病监测计划的效率。它还讨论了一些最新颖的生物标志物,可以潜在地用于识别临床前疾病状态,这将有可能最大限度地减少生产疾病的负面影响。最后,本章展望了未来的前景和可能面临的挑战,未来的自动化疾病监测系统将需要面对,以保持最佳的动物健康,性能和福利在单个畜群。
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引用次数: 0
期刊
Improving dairy herd health Improving
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