Pub Date : 2025-01-01Epub Date: 2024-12-19DOI: 10.1055/a-2381-7937
{"title":"Author commentary on Carlos Fernandes et al.","authors":"","doi":"10.1055/a-2381-7937","DOIUrl":"https://doi.org/10.1055/a-2381-7937","url":null,"abstract":"","PeriodicalId":11516,"journal":{"name":"Endoscopy","volume":"57 1","pages":"v3"},"PeriodicalIF":11.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01Epub Date: 2024-09-03DOI: 10.1055/a-2382-5891
Yusuke Fujiyoshi, Kareem Khalaf, Daniel Tham, Mary Raina Angeli Fujiyoshi, Natalia C Calo, Jeffrey D Mosko, Gary R May, Christopher W Teshima
Background: Endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) are effective treatments for Barrett's neoplasia. However, little is known about recurrence rates following these techniques. We compared long-term neoplasia recurrence rates following EMR and ESD.
Methods: This study included patients with Barrett's neoplasia (high grade dysplasia/adenocarcinoma) treated between July 2019 and December 2023 at a tertiary referral center in Canada. Outcomes were residual neoplasia at first follow-up, complete remission of neoplasia (CRN), and neoplasia recurrence following CRN.
Results: 157 patients were included (87 EMR, 70 ESD). Compared with EMR, the ESD group had larger lesions (median 2 vs. 3 cm, P<0.05), more adenocarcinoma (85.1% vs. 94.3%, P = 0.07), and deeper submucosal invasion (T1a: 71.6% vs. 75.8%; T1b-SM1: 25.7% vs. 6.1%; T1b≥SM2: 2.7% vs. 18.2%; P<0.05). Among 124 patients with follow-up (71 EMR, 53 ESD), 84.9% of ESD-treated patients had curative resections (i.e. R0 resection with low risk for lymph node metastasis), whereas 94.4% of EMR-treated patients had deep margin R0 resection of low risk lesions. At first follow-up, residual neoplasia (14.1% vs. 11.3%) and CRN (97.2% vs. 100%) were similar in the EMR and ESD groups, but neoplasia recurrence following CRN was significantly higher with EMR (13% vs. 1.9%, P<0.05), with cumulative probability of recurrence at 3 years of 18.3% vs. 4.2%, respectively.
Conclusions: Neoplasia recurrence following CRN was significantly higher following EMR compared with ESD, suggesting that ESD may be superior to EMR in preventing neoplasia recurrence in Barrett's esophagus.
背景:内镜粘膜切除术(EMR)和内镜粘膜下剥离术(ESD)是治疗巴雷特瘤的有效方法。然而,人们对这些技术的复发率知之甚少。我们比较了 EMR 和 ESD 术后的长期肿瘤复发率:本研究纳入了2019年7月至2023年12月期间在加拿大一家三级转诊中心接受治疗的巴雷特肿瘤(高级别发育不良/腺癌)患者。结果为首次随访时肿瘤残留、肿瘤完全缓解(CRN)和CRN后肿瘤复发:共纳入 157 例患者(87 例 EMR,70 例 ESD)。与EMR相比,ESD组患者的病灶更大(中位2 cm vs. 3 cm,PP = 0.07),粘膜下浸润更深(T1a:71.6% vs. 75.8%;T1b-SM1:25.7% vs. 6.1%;T1b≥SM2:2.7% vs. 18.2%;PPConclusions:与ESD相比,EMR术后CRN的肿瘤复发率明显更高,这表明ESD在预防巴雷特食管肿瘤复发方面可能优于EMR。
{"title":"Recurrence following successful eradication of neoplasia with endoscopic mucosal resection compared with endoscopic submucosal dissection in Barrett's esophagus: a retrospective comparison.","authors":"Yusuke Fujiyoshi, Kareem Khalaf, Daniel Tham, Mary Raina Angeli Fujiyoshi, Natalia C Calo, Jeffrey D Mosko, Gary R May, Christopher W Teshima","doi":"10.1055/a-2382-5891","DOIUrl":"10.1055/a-2382-5891","url":null,"abstract":"<p><strong>Background: </strong>Endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) are effective treatments for Barrett's neoplasia. However, little is known about recurrence rates following these techniques. We compared long-term neoplasia recurrence rates following EMR and ESD.</p><p><strong>Methods: </strong>This study included patients with Barrett's neoplasia (high grade dysplasia/adenocarcinoma) treated between July 2019 and December 2023 at a tertiary referral center in Canada. Outcomes were residual neoplasia at first follow-up, complete remission of neoplasia (CRN), and neoplasia recurrence following CRN.</p><p><strong>Results: </strong>157 patients were included (87 EMR, 70 ESD). Compared with EMR, the ESD group had larger lesions (median 2 vs. 3 cm, <i>P</i><0.05), more adenocarcinoma (85.1% vs. 94.3%, <i>P</i> = 0.07), and deeper submucosal invasion (T1a: 71.6% vs. 75.8%; T1b-SM1: 25.7% vs. 6.1%; T1b≥SM2: 2.7% vs. 18.2%; <i>P</i><0.05). Among 124 patients with follow-up (71 EMR, 53 ESD), 84.9% of ESD-treated patients had curative resections (i.e. R0 resection with low risk for lymph node metastasis), whereas 94.4% of EMR-treated patients had deep margin R0 resection of low risk lesions. At first follow-up, residual neoplasia (14.1% vs. 11.3%) and CRN (97.2% vs. 100%) were similar in the EMR and ESD groups, but neoplasia recurrence following CRN was significantly higher with EMR (13% vs. 1.9%, <i>P</i><0.05), with cumulative probability of recurrence at 3 years of 18.3% vs. 4.2%, respectively.</p><p><strong>Conclusions: </strong>Neoplasia recurrence following CRN was significantly higher following EMR compared with ESD, suggesting that ESD may be superior to EMR in preventing neoplasia recurrence in Barrett's esophagus.</p>","PeriodicalId":11516,"journal":{"name":"Endoscopy","volume":" ","pages":"5-13"},"PeriodicalIF":11.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142125156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01Epub Date: 2024-12-19DOI: 10.1055/a-2388-6548
{"title":"Author commentary on Belén Martinez-Moreno et al.","authors":"","doi":"10.1055/a-2388-6548","DOIUrl":"https://doi.org/10.1055/a-2388-6548","url":null,"abstract":"","PeriodicalId":11516,"journal":{"name":"Endoscopy","volume":"57 1","pages":"v4"},"PeriodicalIF":11.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01Epub Date: 2024-12-19DOI: 10.1055/a-2386-9046
Andrea Sorge, Giulia Tosetti, Massimo Primignani, Gian Eugenio Tontini
{"title":"Band-on-band endoscopic variceal ligation and alternative treatment strategies: Reply to Hu et al.","authors":"Andrea Sorge, Giulia Tosetti, Massimo Primignani, Gian Eugenio Tontini","doi":"10.1055/a-2386-9046","DOIUrl":"https://doi.org/10.1055/a-2386-9046","url":null,"abstract":"","PeriodicalId":11516,"journal":{"name":"Endoscopy","volume":"57 1","pages":"90-91"},"PeriodicalIF":11.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01Epub Date: 2024-12-19DOI: 10.1055/a-2386-9001
Ye Hu, Yi Zhang, Leiming Xu
{"title":"Comments on \"Band-on-band endoscopic variceal ligation: a technique for the treatment of esophageal varices in case of band misplacement\".","authors":"Ye Hu, Yi Zhang, Leiming Xu","doi":"10.1055/a-2386-9001","DOIUrl":"https://doi.org/10.1055/a-2386-9001","url":null,"abstract":"","PeriodicalId":11516,"journal":{"name":"Endoscopy","volume":"57 1","pages":"90"},"PeriodicalIF":11.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01Epub Date: 2024-09-16DOI: 10.1055/a-2398-9277
Miguel Areia
{"title":"Post-endoscopy upper gastrointestinal cancer: how to move from the dark side.","authors":"Miguel Areia","doi":"10.1055/a-2398-9277","DOIUrl":"10.1055/a-2398-9277","url":null,"abstract":"","PeriodicalId":11516,"journal":{"name":"Endoscopy","volume":" ","pages":"29-30"},"PeriodicalIF":11.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142282155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01Epub Date: 2024-12-19DOI: 10.1055/a-2381-7867
{"title":"Author commentary on Alexander Waldthaler et al.","authors":"","doi":"10.1055/a-2381-7867","DOIUrl":"https://doi.org/10.1055/a-2381-7867","url":null,"abstract":"","PeriodicalId":11516,"journal":{"name":"Endoscopy","volume":"57 1","pages":"v1"},"PeriodicalIF":11.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}