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Spinal tumours 脊柱肿瘤
Pub Date : 2019-09-01 DOI: 10.1093/med/9780198746706.003.0063
J. Brecknell, Quah Boon Leong
Spinal tumours in adults, although usually presenting with pain and neurological dysfunction, are often incidental findings. For the spinal neurosurgeon, the range of pathologies, clinical presentations, and required surgical techniques included within the management of spinal neoplasia is vast, from benign lesions unchanged over a decade of observation to malignant disease that progresses over a few hours to paraplegia, and from the finest microsurgery to instrumentation over multiple spinal segments. Surgery has a key role to play in the management of many of these, both to decompress the neurological elements of the spine and, when necessary, to reconstruct the mechanical integrity of the spine. This chapter highlights some of the challenges facing the contemporary spinal tumour surgeon.
成人脊柱肿瘤,虽然通常表现为疼痛和神经功能障碍,但往往是偶然发现的。对于脊髓神经外科医生来说,脊髓瘤的病理、临床表现和所需的手术技术的范围是巨大的,从十年观察不变的良性病变到几个小时发展到截瘫的恶性疾病,从最精细的显微手术到多节段的内固定。手术在许多此类疾病的治疗中起着关键作用,既可以对脊柱的神经系统进行减压,也可以在必要时重建脊柱的机械完整性。本章重点介绍了当代脊柱肿瘤外科医生面临的一些挑战。
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引用次数: 0
Pineal tumours 松果体肿瘤
Pub Date : 2019-09-01 DOI: 10.1093/med/9780198746706.003.0036
M. Waqar, S. Mills, C. Mallucci, M. Jenkinson
Tumours of the pineal are very rare, tend to be more common in children and while there are a wide variety of pathologies the majority are germ cell tumours and pineal parenchymal tumours. These tumours usually present with hydrocephalus and endoscopic third ventriculostomy is the operation of choice. It is important to test for tumour markers in the blood and cerebrospinal fluid, since the diagnosis of a secreting germ cell tumour precludes the need for surgery. Surgical biopsy can be performed by endoscopy or with frame-based stereotaxy. For germ cell tumours chemotherapy and radiotherapy are the mainstay of treatment, but surgery has a role in the management of residual disease. For primary parenchymal tumours, maximum surgical resection is the first-line treatment and can be curative for pineocytoma. Pineoblastoma require adjuvant radiotherapy and for intermediate grade pineal tumours the role of radiotherapy is still being evaluated.
松果体肿瘤是非常罕见的,往往更常见于儿童,虽然有各种各样的病理,大多数是生殖细胞肿瘤和松果体实质肿瘤。这些肿瘤通常伴有脑积水,内镜下第三脑室造口术是首选手术。检测血液和脑脊液中的肿瘤标志物是很重要的,因为分泌性生殖细胞肿瘤的诊断排除了手术的需要。手术活检可以通过内窥镜或框架立体定位进行。对于生殖细胞肿瘤,化疗和放疗是主要的治疗方法,但手术在残余疾病的管理中也有作用。对于原发性实质肿瘤,最大限度的手术切除是一线治疗,可以治愈松果体细胞瘤。松果体母细胞瘤需要辅助放疗,对于中度松果体肿瘤,放疗的作用仍在评估中。
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引用次数: 0
Complications of head injury 头部损伤并发症
Pub Date : 2019-09-01 DOI: 10.1093/med/9780198746706.003.0044
F. Afshari, Antonio Belli, Peter C. Whitfield
Traumatic brain injury is a potentially devastating condition that affects many young adults and is increasingly seen in older people. In addition to initial insult to the neuronal tissue at the time injury, patients with traumatic brain injury may suffer from many physical and psychological complications. These complications further protract the path of recovery and pose challenges in treatment of this group of patients. In this chapter we aim to discuss early and late phase complications following traumatic brain injury and summarize the role of neurorehabilitation in the care of patients with head injury, with the understanding that classification by timing is an inexact science and there is considerable overlap between early and late complications.
创伤性脑损伤是一种潜在的破坏性疾病,影响许多年轻人,并且越来越多地出现在老年人身上。创伤性脑损伤患者除了在损伤时对神经组织的初始损伤外,还可能出现许多生理和心理并发症。这些并发症进一步延长了康复的道路,并对这组患者的治疗提出了挑战。在本章中,我们的目的是讨论创伤性脑损伤后的早期和晚期并发症,并总结神经康复在脑损伤患者护理中的作用,理解按时间分类是一门不精确的科学,早期和晚期并发症之间存在相当大的重叠。
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引用次数: 37
Surgical management of pineal region lesions 松果体区病变的外科治疗
Pub Date : 2019-09-01 DOI: 10.1093/med/9780198746706.003.0037
C. Woernle, R. Bernays, N. Tribolet
Lesions in the pineal region are topographically located in the centre of the brain in the diencephalic-epithalamic region. An area where the brain is bounded ventrally by the quadrigeminal plate, midbrain tectum, and in-between the left and right superior colliculi, dorsally by the splenium of the corpus callosum, caudally by the cerebellar vermis and rostrally by the posterior aspects of the third ventricle. Major anatomical and surgical challenges are the vein of Galen located dorsally, the precentral cerebellar vein caudally, the internal cerebral veins anteriorly and the basal vein of Rosenthal laterally. Most pineal region tumours can be safely removed by both approaches depending on the surgeon’s experience: the occipital transtentorial approach is recommended in presence of associated hydrocephalus or a steep straight sinus and low location of the tumour and the supracerebellar infratentorial approach for posterior third ventricle tumours.
松果体区域的病变在地形上位于大脑中心的间脑-上皮区。脑区大脑在腹侧由四叉肌板、中脑顶盖和左右上丘之间连接的区域,背侧由胼胝体的脾部连接,尾端由小脑蚓部连接,背侧由第三脑室的后部连接主要的解剖和手术难点是位于背侧的盖伦静脉、位于尾侧的小脑中央前静脉、位于前侧的脑内静脉和位于外侧的罗森塔尔基静脉。根据外科医生的经验,大多数松果体区域肿瘤可通过两种入路安全切除:当存在脑积水或肿瘤位置较低且呈陡峭直窦时,建议采用枕部经小脑幕下入路;对于后第三脑室肿瘤,建议采用小脑上小脑幕下入路。
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引用次数: 0
Spinal infection 脊髓感染
Pub Date : 2019-09-01 DOI: 10.1093/med/9780198746706.003.0099
N. Haden, E. White
This chapter provides a comprehensive review of the presentation, investigation, and management of patients presenting with a spinal infection. Particular attention is given to discitis and osteomyelitis (collectively referred to as spondylodiscitis), spinal epidural abscesses, and postoperative infections following spine surgery, although in practice there is considerable overlap between these conditions. These forms of spinal infection are rare, but are associated with significant morbidity and mortality, often due to diagnostic delays related to their non-specific presenting symptoms. The relevant literature is reviewed and summarized to provide guidance on the prompt diagnosis and management of these conditions in clinical medical practice.
本章提供了一个全面的审查的介绍,调查和管理的病人提出了脊柱感染。特别关注椎间盘炎和骨髓炎(统称为脊椎椎间盘炎)、脊髓硬膜外脓肿和脊柱手术后感染,尽管在实践中这些情况有相当大的重叠。这些形式的脊髓感染是罕见的,但与显著的发病率和死亡率相关,通常是由于与非特异性表现症状相关的诊断延迟。本文对相关文献进行回顾和总结,为临床医学实践中及时诊断和处理这些疾病提供指导。
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引用次数: 0
Surgical management of anterolateral skull base lesions 颅底前外侧病变的外科治疗
Pub Date : 2019-09-01 DOI: 10.1093/med/9780198746706.003.0021
M. Cusimano, Michael P. Meier
The following section outlines major considerations in the treatment of anterolateral skull base lesions. The essential anatomy, including the nasosinal region as well as the anterior fossa, is presented and the related challenge of defining the appropriate surgical approach is highlighted. We report on our principles of preoperative investigations and demonstrate the cornerstones of the perisurgical treatment for patients with lesions of the anterolateral skull base in our department. The chapter focuses on surgical decision-making and surgical techniques, it covers the most relevant approaches in managing anterolateral lesions. Detailed descriptions of the anterior interhemispheric approach, the supraorbital craniotomy, and minicraniotomy, the extended endoscopic endonasal approach, the orbitozygomatic approach, and the Fisch approaches are provided. Finally, we present and discuss the surgically relevant nuances of four selected cases to highlight and discuss the controversies for and against the choice of a particular approach.
以下部分概述了治疗前外侧颅底病变的主要考虑因素。基本解剖,包括鼻鼻区和前窝,提出了确定适当手术入路的相关挑战。我们报告了我们的术前调查原则,并展示了我们科前外侧颅底病变患者围手术治疗的基石。本章侧重于手术决策和手术技术,它涵盖了管理前外侧病变最相关的方法。详细描述了前半球间入路、眶上开颅术、小颅骨开颅术、扩展内窥镜鼻内入路、眶颧入路和Fisch入路。最后,我们提出并讨论四个选定病例的外科相关细微差别,以突出和讨论支持和反对选择特定方法的争议。
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引用次数: 0
Surgical approaches to posterior fossa tumours 后窝肿瘤的手术入路
Pub Date : 2019-09-01 DOI: 10.1093/med/9780198746706.003.0031
J. Morcos, O. Khan, Ashish H. Shah
Lesions of the fourth ventricle and foramen magnum can be difficult to manage surgically due to their proximity to critical brainstem structures. Understanding the anatomy of the fourth ventricle, lower cranial nerves, and basilar cisterns remains paramount for deciding surgical approaches to this location. Detailed preoperative workup and planning are necessary to minimize surgical morbidity and maximize tumour resection. This chapter provides an overview of the relevant anatomy and surgical techniques for lesions in the posterior fossa, specifically the fourth ventricle the foramen magnum. We will split this chapter into two main sections: microsurgical approaches to the fourth ventricle and skull base approaches to the foramen magnum.
由于第四脑室和枕骨大孔靠近关键的脑干结构,因此很难通过手术治疗。了解第四脑室、下颅神经和基底池的解剖结构对于确定该部位的手术入路至关重要。详细的术前检查和计划是必要的,以尽量减少手术发病率和最大限度地切除肿瘤。本章概述了后窝病变的相关解剖和手术技术,特别是第四脑室和枕骨大孔病变。我们将把这一章分成两个主要部分:第四脑室的显微手术入路和枕骨大孔的颅底入路。
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引用次数: 0
Shunt technology and endoscopic ventricular surgery 分流技术和内窥镜心室手术
Pub Date : 2019-09-01 DOI: 10.1093/med/9780198746706.003.0093
I. Pople, W. Singleton
The management of cerebrospinal fluid (CSF) disorders via CSF diversion is now a complex clinical science, requiring a detailed understanding of CSF physiology in both the normal and diseased brain. Successful treatment of this group of disorders requires a comprehensive knowledge of all the available shunt types, their similarities, differences, and idiosyncrasies. The rapid development of endoscopic neurosurgical techniques makes treating this group of patients without a shunt often a real possibility, and arguably is now a core neurosurgical skill. In this chapter we will summarize the CSF physiology in the normal state, and explain the principles of CSF diversion before going on to describe the various shunt types available. A section will be devoted to endoscopic CSF diversion techniques, including a detailed explanation of third ventriculostomy.
通过脑脊液分流治疗脑脊液紊乱是一门复杂的临床科学,需要详细了解正常脑和病变脑的脑脊液生理学。成功治疗这类疾病需要全面了解所有可用的分流类型,它们的异同和特质。内窥镜神经外科技术的快速发展使得无需分流术治疗这类患者成为可能,并且可以说现在是一项核心神经外科技术。在本章中,我们将总结正常状态下的脑脊液生理学,并在继续描述各种可用的分流类型之前解释脑脊液分流的原理。一节将专门介绍内窥镜脑脊液转移技术,包括第三脑室造口术的详细解释。
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引用次数: 0
Spasticity 痉挛状态
Pub Date : 2019-09-01 DOI: 10.1093/med/9780198746706.003.0077
J. Goodden, C. Hernon, B. Scott
This chapter reviews the aetiology, pathophysiology, assessment, and treatment of spasticity in adults and children. We present an overview of the medical management options as well as the multidisciplinary input and rehabilitation required. Surgical interventions are then outlined with more sections on neurosurgery, plastic surgery, and orthopaedic surgery. The mainstay of neurosurgical treatment has traditionally involved intrathecal baclofen, however, there is now a renewed focus on the role of selective dorsal rhizotomy for the more mobile children. Both these surgical techniques are explained and discussed. Plastic surgery intervention with selective peripheral neurotomy and splinting is then described. In addition, orthopaedic surgery (single event multilevel surgery and bone/joint reconstruction) is discussed in outline. Finally, a brief overview of current controversies is also presented. Carefully planned and coordinated multidisciplinary team care is vital to ensure patients have appropriately-tailored treatment to maximize their potential and limit the deleterious effects of spasticity.
本章回顾了成人和儿童痉挛的病因、病理生理学、评估和治疗。我们提出的医疗管理方案的概述,以及多学科的投入和康复所需。手术干预,然后概述了更多的章节神经外科,整形外科和矫形外科。传统上,神经外科治疗的主要方法是鞘内注射巴氯芬,然而,现在人们重新关注选择性背根切开术对活动能力更强的儿童的作用。这两种手术技术都进行了解释和讨论。然后描述了选择性周围神经切开术和夹板的整形手术干预。此外,骨科手术(单事件多节段手术和骨/关节重建)进行了概要讨论。最后,简要概述了当前的争议。精心计划和协调的多学科团队护理是至关重要的,以确保患者有适当的量身定制的治疗,以最大限度地发挥他们的潜力,并限制痉挛的有害影响。
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引用次数: 0
Cervical spinal disease 颈椎病
Pub Date : 2019-09-01 DOI: 10.1093/med/9780198746706.003.0060
N. Furtado, G. Tsermoulas, A. Silva
Degenerative cervical spinal disease refers to neck pain, myelopathy, and/or radiculopathy. It is a common problem with increased prevalence above the age of 55 years. Understanding the natural history and pathophysiology is crucial in selecting patients for surgery. The degenerative pathological processes that can occur in the cervical spine include degenerative disc disease, degenerative cervical myelopathy, ossification of the posterior longitudinal ligament (OPLL) and ossification of the ligamentum flavum (OLF). There are also systemic diseases affecting the cervical spine and these include rheumatoid disease, sero-negative spondyloarthropathies and diffuse idiopathic skeletal hyperostosis (DISH). This section describes the pathology of cervical spinal disease, the clinical management, surgical approaches, and controversies in the field.
退行性颈椎疾病是指颈部疼痛、脊髓病和/或神经根病。这是一种常见的问题,55岁以上的患病率增加。了解自然病史和病理生理学是选择手术患者的关键。可发生在颈椎的退行性病理过程包括退行性椎间盘病、退行性颈脊髓病、后纵韧带骨化(OPLL)和黄韧带骨化(OLF)。还有影响颈椎的全身性疾病,包括类风湿病、血清阴性的脊椎关节病和弥漫性特发性骨骼肥大症(DISH)。本节描述了颈椎疾病的病理,临床管理,手术方法,并在该领域的争议。
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引用次数: 0
期刊
Oxford Textbook of Neurological Surgery
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