Pub Date : 2024-12-01DOI: 10.1016/j.eprac.2024.08.010
Jennifer A. Sipos MD
The rapid evolution of ultrasound (US) technology has dramatically changed the medical field. Ideally suited for evaluation of anatomic disorders of the thyroid, coupled with its ease of use at the bedside, US has become an essential tool for endocrinologists over the last 50 years. This noninvasive technology provides a sensitive and specific instrument for malignancy risk prediction of thyroid nodules, surveillance for recurrent thyroid cancer, and diagnosis of autoimmune thyroid disorders. While US has proven invaluable for such diagnostic purposes, its extensive use also has resulted in important negative consequences. This review will discuss the evolution of US equipment for the evaluation of thyroid disorders, its use in interventional procedures, and the unintended outcomes from the widespread adoption of this technology. Finally, this article will explore the potential future applications for US technology and its related advancements.
超声（US）技术的飞速发展极大地改变了医学领域。US 非常适合评估甲状腺解剖疾病，而且在床边使用方便，在过去的 50 年里已成为内分泌科医生的必备工具。这种无创技术为甲状腺结节的恶性风险预测、复发性甲状腺癌的监测以及自身免疫性甲状腺疾病的诊断提供了灵敏而特异的工具。尽管 US 已被证明对这些诊断目的具有重要价值，但它的广泛应用也带来了重要的负面影响。本综述将讨论用于评估甲状腺疾病的 US 设备的演变、其在介入手术中的应用以及广泛采用该技术所带来的意外后果。最后，本文将探讨 US 技术未来的潜在应用及其相关进展。
{"title":"The History of Thyroid Ultrasound: Past, Present, and Future Directions","authors":"Jennifer A. Sipos MD","doi":"10.1016/j.eprac.2024.08.010","DOIUrl":"10.1016/j.eprac.2024.08.010","url":null,"abstract":"<div><div>The rapid evolution of ultrasound (US) technology has dramatically changed the medical field. Ideally suited for evaluation of anatomic disorders of the thyroid, coupled with its ease of use at the bedside, US has become an essential tool for endocrinologists over the last 50 years. This noninvasive technology provides a sensitive and specific instrument for malignancy risk prediction of thyroid nodules, surveillance for recurrent thyroid cancer, and diagnosis of autoimmune thyroid disorders. While US has proven invaluable for such diagnostic purposes, its extensive use also has resulted in important negative consequences. This review will discuss the evolution of US equipment for the evaluation of thyroid disorders, its use in interventional procedures, and the unintended outcomes from the widespread adoption of this technology. Finally, this article will explore the potential future applications for US technology and its related advancements.</div></div>","PeriodicalId":11682,"journal":{"name":"Endocrine Practice","volume":"30 12","pages":"Pages 1220-1226"},"PeriodicalIF":3.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142139660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-01DOI: 10.1016/j.eprac.2024.09.006
David A. Goodkin MD
{"title":"Adrenocortical Carcinoma and the Mitotane Morass: A Physician/Patient Perspective","authors":"David A. Goodkin MD","doi":"10.1016/j.eprac.2024.09.006","DOIUrl":"10.1016/j.eprac.2024.09.006","url":null,"abstract":"","PeriodicalId":11682,"journal":{"name":"Endocrine Practice","volume":"30 12","pages":"Pages 1242-1243"},"PeriodicalIF":3.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142264363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-01DOI: 10.1016/j.eprac.2024.09.007
Pranav Gupta MD , Luisa Marin Cunha , Daniela Diego MD , Vin Tangpricha MD, PhD
Objective
Gender-affirming hormone therapy (GAHT) is often used by transgender and gender-diverse individuals to align their physical appearance with their gender identity. Discontinuation rates and factors leading to discontinuation of GAHT are not fully understood. We aimed to assess the continuation and discontinuation rates of GAHT and the factors leading to discontinuation of GAHT in a systematic review of the literature.
Methods
We searched PubMed from 2009 until April 01, 2024, for all published studies that described initiation, discontinuation, and reasons for discontinuation of GAHT. Studies were screened by 2 authors independently. We included 6 studies that met the inclusion and exclusion criteria published between 2021 and 2024.
Results
Five studies reported GAHT discontinuation rates under 10%, whereas 1 study reported a discontinuation/lost to follow-up rate of 30.8%. Only 1 study was prospective, whereas all other studies were retrospective. Reasons for discontinuation of GAHT were described in only 2 studies. One study reported GAHT discontinuation primarily from external factors, whereas the other study suggested that GAHT discontinuation occurred due to change in gender identity.
Conclusion
Current data on discontinuation of GAHT show that the rates of GAHT discontinuation appear to be low and the reasons include both external pressures and internal change of gender identity. A better understanding of the internal and external pressures that impact the decision to continue GAHT is needed in future studies.
{"title":"Continuation of Gender-Affirming Hormone Therapy in Transgender and Gender-Diverse Individuals: A Systematic Review","authors":"Pranav Gupta MD , Luisa Marin Cunha , Daniela Diego MD , Vin Tangpricha MD, PhD","doi":"10.1016/j.eprac.2024.09.007","DOIUrl":"10.1016/j.eprac.2024.09.007","url":null,"abstract":"<div><h3>Objective</h3><div>Gender-affirming hormone therapy (GAHT) is often used by transgender and gender-diverse individuals to align their physical appearance with their gender identity. Discontinuation rates and factors leading to discontinuation of GAHT are not fully understood. We aimed to assess the continuation and discontinuation rates of GAHT and the factors leading to discontinuation of GAHT in a systematic review of the literature.</div></div><div><h3>Methods</h3><div>We searched PubMed from 2009 until April 01, 2024, for all published studies that described initiation, discontinuation, and reasons for discontinuation of GAHT. Studies were screened by 2 authors independently. We included 6 studies that met the inclusion and exclusion criteria published between 2021 and 2024.</div></div><div><h3>Results</h3><div>Five studies reported GAHT discontinuation rates under 10%, whereas 1 study reported a discontinuation/lost to follow-up rate of 30.8%. Only 1 study was prospective, whereas all other studies were retrospective. Reasons for discontinuation of GAHT were described in only 2 studies. One study reported GAHT discontinuation primarily from external factors, whereas the other study suggested that GAHT discontinuation occurred due to change in gender identity.</div></div><div><h3>Conclusion</h3><div>Current data on discontinuation of GAHT show that the rates of GAHT discontinuation appear to be low and the reasons include both external pressures and internal change of gender identity. A better understanding of the internal and external pressures that impact the decision to continue GAHT is needed in future studies.</div></div>","PeriodicalId":11682,"journal":{"name":"Endocrine Practice","volume":"30 12","pages":"Pages 1206-1211"},"PeriodicalIF":3.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142282250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-30DOI: 10.1016/j.eprac.2024.11.010
Omorogieva Ojo, Joshua Boateng, Rosana Pacella, Ann Hanrahan, Ryan Essex, Lesley Dibley
Objective: The objective of this scoping review is to explore the experiences of patients' and healthcare practitioners on the factors that influence the care and management of diabetes-related foot ulcers (DFUs).
Methods: Levac et al's 6-stage framework and the Preferred Reporting Items for Systematic Review and Meta-analysis extension for scoping reviews, guided the review. The SPIDER tool was used to define key elements of the review question. Searches for relevant articles were conducted in electronic databases (PUBMED, CINAHL, AMED, Embase, Cochrane Database of Systematic Reviews, and PsycINFO), Google Scholar, and hand searches of reference lists.
Results: Eight articles met the inclusion criteria and were included in the review. Three themes were identified: Communication and Education about DFUs; Challenges of managing DFUs; and Barriers to treatment and management. The themes are presented as a narrative synthesis.
Conclusion: Inadequate knowledge of diabetic foot care by patients and inconsistent communication by healthcare professionals were primary factors affecting the effective management of diabetes-related foot ulcers. Consistent, patient-focused education that is supported by knowledgeable health care professionals should form the foundation of effective diabetic foot ulcer care.
目的：本综述的目的是探讨影响糖尿病相关足溃疡（DFUs）的护理和管理因素的患者和医疗保健从业人员的经验。方法：Levac等提出的六阶段框架，以及系统评价的首选报告项目和范围评价的元分析扩展，对综述进行指导。使用SPIDER工具定义审查问题的关键要素。在电子数据库（PUBMED、CINAHL、AMED、Embase、Cochrane Database of Systematic Reviews、PsycINFO）、谷歌Scholar和参考文献手工检索中检索相关文章。结果：8篇文章符合纳入标准，被纳入综述。确定了三个主题：关于dfu的交流和教育；管理dfu的挑战；治疗和管理方面的障碍。这些主题是作为一种叙事综合来呈现的。结论：患者对糖尿病足部护理知识的缺乏和医护人员沟通的不一致是影响糖尿病足部溃疡有效管理的主要因素。在知识渊博的卫生保健专业人员的支持下，一致的、以患者为中心的教育应该成为有效的糖尿病足溃疡护理的基础。
{"title":"Factors Influencing the Care and Management of Diabetic Foot Ulcers: A Scoping Review.","authors":"Omorogieva Ojo, Joshua Boateng, Rosana Pacella, Ann Hanrahan, Ryan Essex, Lesley Dibley","doi":"10.1016/j.eprac.2024.11.010","DOIUrl":"10.1016/j.eprac.2024.11.010","url":null,"abstract":"<p><strong>Objective: </strong>The objective of this scoping review is to explore the experiences of patients' and healthcare practitioners on the factors that influence the care and management of diabetes-related foot ulcers (DFUs).</p><p><strong>Methods: </strong>Levac et al's 6-stage framework and the Preferred Reporting Items for Systematic Review and Meta-analysis extension for scoping reviews, guided the review. The SPIDER tool was used to define key elements of the review question. Searches for relevant articles were conducted in electronic databases (PUBMED, CINAHL, AMED, Embase, Cochrane Database of Systematic Reviews, and PsycINFO), Google Scholar, and hand searches of reference lists.</p><p><strong>Results: </strong>Eight articles met the inclusion criteria and were included in the review. Three themes were identified: Communication and Education about DFUs; Challenges of managing DFUs; and Barriers to treatment and management. The themes are presented as a narrative synthesis.</p><p><strong>Conclusion: </strong>Inadequate knowledge of diabetic foot care by patients and inconsistent communication by healthcare professionals were primary factors affecting the effective management of diabetes-related foot ulcers. Consistent, patient-focused education that is supported by knowledgeable health care professionals should form the foundation of effective diabetic foot ulcer care.</p>","PeriodicalId":11682,"journal":{"name":"Endocrine Practice","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142767085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-19DOI: 10.1016/j.eprac.2024.09.098
Sumerah Jabeen FCPS, Nimra Siddiqui, Saba Akhtar
{"title":"Abstract #1913275 A Case Series of Rare Mayer-Rokitansky-Kuster-Hauser Syndrome Variants: Navigating the Uncharted Waters","authors":"Sumerah Jabeen FCPS, Nimra Siddiqui, Saba Akhtar","doi":"10.1016/j.eprac.2024.09.098","DOIUrl":"10.1016/j.eprac.2024.09.098","url":null,"abstract":"","PeriodicalId":11682,"journal":{"name":"Endocrine Practice","volume":"30 12","pages":"Page S35"},"PeriodicalIF":3.7,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142697631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-19DOI: 10.1016/j.eprac.2024.09.086
Sadeem Aldawas, Aishah Ekhzaimy, Muhammad Mujammami
{"title":"Abstract #1902456 Clinical Case of Insulin Autoimmune Syndrome in a 44-Year-Old Saudi Woman","authors":"Sadeem Aldawas, Aishah Ekhzaimy, Muhammad Mujammami","doi":"10.1016/j.eprac.2024.09.086","DOIUrl":"10.1016/j.eprac.2024.09.086","url":null,"abstract":"","PeriodicalId":11682,"journal":{"name":"Endocrine Practice","volume":"30 12","pages":"Pages S29-S30"},"PeriodicalIF":3.7,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142703955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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