Background: Mental disorders are a major and evolving contributor to morbidity among women of child-bearing age (WCBA). However, long-term trends, geographic inequalities, and the future burden in this population remain incompletely characterised. We quantified the burden of mental disorders among WCBA (15-49 years) from 1990 to 2021 and projected trends to 2050.
Methods: We assessed the burden of 10 mental disorder categories among WCBA aged 15-49 years in 204 countries and territories using GBD 2021, including 9 specified mental disorders and a residual category ("other mental disorders"). We analysed prevalence and disability-adjusted life-years (DALYs) as numbers and age-standardised rates (ASPR and ASDR). A Bayesian age-period-cohort model was used to generate projections through 2050.
Results: Overall, ASPR and ASDR declined from 1990 to 2019; compared with the pre-pandemic baseline in 2019, both indicators were higher in 2020-2021. Age-specific prevalence generally increased with age and peaked at 40-44 years, although patterns differed by disorder category. At the national level, Greenland and Portugal had the highest ASPR and ASDR, whereas Vietnam had the lowest prevalence and North Korea had the lowest DALYs. Across the 21 GBD regions, higher SDI was associated with higher ASPR and ASDR, with marked regional heterogeneity. Projections suggested that the burden of mental disorders among WCBA will increase through 2050, largely driven by anxiety and depressive disorders.
Conclusions: The burden of mental disorders among WCBA remains substantial and is projected to rise through 2050, with increases during 2020-2021 relative to the 2019 baseline. These findings underscore the need for context-specific strategies that strengthen surveillance and expand accessible prevention and care-particularly for anxiety and depressive disorders-across diverse sociodemographic settings.
扫码关注我们
求助内容:
应助结果提醒方式:
