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Impact of epicardial adipose tissue on coronary arteries thrombus burden and early outcomes in STEMI patients 心外膜脂肪组织对STEMI患者冠状动脉血栓负荷和早期结局的影响
4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-09-01 DOI: 10.1093/eurheartjsupp/suad113.009
Gehan Magdy Yousef, Mahmoud Muhamed Hassanein, Aly Alsaid Zidan, Diaaaldin Taha Zahran
Abstract Aim Evaluation the relationship between the epicardial adipose tissue thickness (EAT), the coronary arteries thrombus burden and the early major adverse cardiovascular events (MACE) in patients presented with STEMI undergoing primary percutaneous coronary intervention. Method The study was prospective and included patients (n = 80) who were referred to the cardiology department in Alexandria University Hospitals with STEMI between the 1st of March 2021 and the last day of August 2022. Patient clinical, laboratory, angiographic and echocardiographic data were described. Patients were put under observation to detect the occurrence of any major adverse cardiovascular events either in hospital or during a period of 30 days follow up. Special concerns for measuring EAT as an echo free space between the myocardium and visceral epicardial and measured perpendicular to the free wall of the right ventricle in parasternal long and short axis views at end diastole and angiographic assessment of thrombus burden was scored as follows: 0 (no thrombus), 1 (possible thrombus), 2 (definite thrombus < 0.5× reference vessel diameter), 3 (definite thrombus 0.5–2× reference vessel diameter), 4 (definite thrombus >2× reference vessel diameter), and 5 (complete vessel occlusion). According to thrombus grade the patients were grouped as low thrombus burden (grades 0–3) and high thrombus burden (grades 4 and 5). Results 25 subjects were in the low thrombus burden group and 55 in the high thrombus burden group. There were no differences in the two groups for age, sex, smoking and drug addiction status, family history of coronary artery disease, diabetes mellitus, hypertension, and total cholesterol, triglyceride, LDL-C and HDL-C, The mean Wall motion score and Wall motion score index. The means levels of high sensitivity troponin I and Creatine Kinase MB are measured higher in the low thrombus burden group with statistically significant difference (P = 0.025) and (P = 0.032). Balloon predilation was statistically significant difference between the two groups (P = 0.006). Thrombus’ aspiration, balloon post dilation of the culprit vessel, GpIIb/IIIa inhibitors, and one stent only were insignificant difference between the two groups. The receiver operating characteristic curve analysis was undergone to determine the cutoff value of EAT to predict the presence of high thrombus burden setting a significance level at P < 0.05. The thickness of 2.48 mm for EAT has 74.55% sensitivity and 72.0% specificity for prediction of the high thrombus burden. The predictors of the high thrombus burden were analyzed by univariate analysis shows EAT, the waist circumference, Wight, the body mass index, and balloon predilation were found as an independent predictors of high thrombus burden. The multivariate analysis shows EAT and balloon predilation were found as an independent predictors of high thrombus burden. The overall MACE at 30 day follows up has statistic
【摘要】目的探讨经皮冠状动脉介入治疗STEMI患者心外膜脂肪组织厚度(EAT)、冠状动脉血栓负荷与早期主要心血管不良事件(MACE)的关系。方法前瞻性研究纳入了2021年3月1日至2022年8月最后一天在亚历山大大学医院心内科转诊的STEMI患者(n = 80)。对患者的临床、实验室、血管造影和超声心动图资料进行了描述。观察患者在医院或30天随访期间是否发生任何重大心血管不良事件。特别需要注意的是,在舒张末期胸骨旁长、短轴位上垂直于右心室自由壁测量EAT作为心肌和脏心外膜之间的无回声空间,以及血栓负荷的血管造影评估,评分如下:0(无血栓),1(可能有血栓),2(明确有血栓);0.5×参考血管直径),3(明确血栓0.5 ~ 2x参考血管直径),4(明确血栓±2x参考血管直径),5(血管完全闭塞)。根据血栓分级将患者分为低血栓负担组(0 ~ 3级)和高血栓负担组(4、5级)。结果低血栓负担组25例,高血栓负担组55例。两组在年龄、性别、吸烟和药物依赖状况、冠心病家族史、糖尿病、高血压、总胆固醇、甘油三酯、LDL-C和HDL-C、平均壁运动评分和壁运动评分指数等方面均无差异。高敏感性肌钙蛋白I和肌酸激酶MB平均水平在血栓负荷低组较高,差异有统计学意义(P = 0.025)和(P = 0.032)。两组间球囊预扩张率差异有统计学意义(P = 0.006)。两组间血栓吸入、罪魁祸首血管球囊扩张、GpIIb/IIIa抑制剂和仅一个支架的差异不显著。进行受试者工作特征曲线分析,确定EAT的截止值,以预测是否存在高血栓负荷,并在P <0.05. 厚度为2.48 mm的EAT预测高血栓负荷的敏感性为74.55%,特异性为72.0%。通过单变量分析分析高血栓负荷的预测因子,发现EAT、腰围、体重、体重指数和球囊预扩张是高血栓负荷的独立预测因子。多变量分析显示EAT和球囊预扩张是高血栓负荷的独立预测因子。血栓负荷低组与血栓负荷高组随访30天总MACE差异无统计学意义。根据心外膜脂肪组织厚度,MACE患者与非MACE患者之间的差异无统计学意义。结论EAT是STEMI患者冠状动脉血栓负荷的独立预测因子。一个作者的视频,伴随着这个摘要可在https://academic.oup.com/eurheartjsupp。请点击“更多内容”旁边的箭头,然后点击“作者视频”。
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引用次数: 0
Immediate, short-term, and long-term effects of balloon mitral valvuloplasty on the left atrial global longitudinal strain and its correlation to the outcomes in patients with severe rheumatic mitral stenosis 球囊二尖瓣成形术对严重风湿性二尖瓣狭窄患者左心房总纵应变的即时、短期和长期影响及其与预后的相关性
4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-09-01 DOI: 10.1093/eurheartjsupp/suad113.008
Amr Setouhi, Hesham Boshra, Hany Askalany, Hazem M A Farrag
Abstract Background Global longitudinal left atrial strain (GLS) has been used as a new assessment tool for left atrial function. Aim To investigate the effect of balloon mitral valvuloplasty (BMV) in patients with severe rheumatic mitral stenosis on GLS and its relation to the mitral valve area achieved after the procedure. Methods The study included 95 patients with severe mitral stenosis who fulfilled the criteria for BMV (case group) and 80 normal healthy subjects (control group). All included participants underwent complete echocardiographic examinations. For the case group, GLS was assessed by 2D speckle-tracking Echocardiography before valvuloplasty, immediately after, within 24 h, at 6 months, and at 12 months, and the results were compared. Results The impaired left-atrium strain in patients with severe mitral stenosis was improved immediately after BMV, and the improvement continued at 6 and 12 months post-BMV (23.1% ± 4.2 vs. 36.0 % ± 4.9, 36.2% ± 4.5, and 40.1% ± 9.5, respectively P &lt; 0.01). After BMV, there was a significant decrease in left atrial volume (76.3 ± 12.4 mL/m2 vs. 68.6 ± 10.4 mL/m2, P &lt; 0.01) and a significant increase in the area occupied by the mitral valve (1.02 ± 0.18 cm2 vs. 1.60 ± 0.31 cm, P &lt; 0.01).The immediate GLS and the mitral valve area were positively correlated (r = 0.64, P &lt; 0.01). Furthermore, the immediate GLS was associated with significantly improved function class (P &lt; 0.01). Conclusion GLS can indicate left atrial function (mainly reservoir function). The improvement observed in patients after BMV may indicate that GLS can be used to evaluate the progress after BMV. Additional Content An author video to accompany this abstract is available on https://academic.oup.com/eurheartjsupp. Please click on the arrow next to ‘More Content’ and then click on ‘Author videos’.
背景全局纵向左心房应变(GLS)是一种评价左心房功能的新方法。目的探讨重度风湿性二尖瓣狭窄患者球囊二尖瓣成形术(BMV)对GLS的影响及其与术后二尖瓣面积的关系。方法选取符合BMV标准的重度二尖瓣狭窄患者95例(病例组)和正常健康者80例(对照组)。所有纳入的参与者都进行了完整的超声心动图检查。对于病例组,在瓣膜成形术前、术后立即、24小时内、6个月和12个月时通过二维斑点跟踪超声心动图评估GLS,并对结果进行比较。结果重度二尖瓣狭窄患者左心房应变受损在BMV后立即得到改善,并在BMV后6个月和12个月持续改善(分别为23.1%±4.2∶36.0%±4.9、36.2%±4.5和40.1%±9.5);0.01)。BMV后左房容积显著降低(76.3±12.4 mL/m2 vs. 68.6±10.4 mL/m2), P <0.01),二尖瓣占用面积显著增加(1.02±0.18 cm2 vs. 1.60±0.31 cm, P <0.01)。即时GLS与二尖瓣面积呈正相关(r = 0.64, P <0.01)。此外,即时GLS与显著改善的功能等级(P <0.01)。结论GLS能反映左心房功能(主要是左心房储血功能)。患者在BMV后观察到的改善可能表明GLS可用于评估BMV后的进展。一个作者的视频,伴随着这个摘要可在https://academic.oup.com/eurheartjsupp。请点击“更多内容”旁边的箭头,然后点击“作者视频”。
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引用次数: 0
Assessment of cardiac functions using two-dimensional transthoracic and speckle tracking echocardiography after treatment with SGLT2 inhibitors in Patients with HFrEF 在HFrEF患者接受SGLT2抑制剂治疗后,使用二维经胸和斑点跟踪超声心动图评估心功能
4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-09-01 DOI: 10.1093/eurheartjsupp/suad113.002
Amr Setouhi, Ashraf Radi, Hany Taha Asklany, Hazem M A Farrag
Abstract Background & objective Recently, the antidiabetic drug sodium-glucose cotransporter type 2 inhibitor (SGLT2i) has been approved among the drugs that reduce mortality in patients with HFrEF. The impact of SGLT2i inhibitors on the left ventricle longitudinal myocardial function in heart failure (HF) patients remained vague. The effect of SGLT2i on left ventricular remodeling and function in patients with HFrEF was studied using STE and traditional echocardiography. Objectives Studying the effects of SGLT2i on left ventricular remodeling and function in HFrEF patients using STE and traditional echocardiography. Methods 300 patients with HFrEF were included.Study design: This prospective observational study involves 300 patients with HFrEF-administered SGLT2i (Empagliflozin & Dapagliflozin) in addition to the classical treatment of heart failure. Then the patients were followed up 2, 4 & 6 months after treatment with laboratory investigations of HbA1C and eGFR, in addition to 2D echo & STE studies. Results Regarding Demographic data, the mean age was 50 ± 9.2 for males and females. The mean weight, height, and body mass index (BMI) were 85.6 ± 8.8 kg, 178.6 ± 7.2 cm, and 26.6 ± 2.9, respectively. The systolic blood pressure (SBP) and diastolic blood pressure (DBP) were 115.3 ± 5.1 and 75.4 ± 4.5, respectively. The mean heart rate was 79.9 ± 10.2. The mean respiratory rate was15 ± 2.2. Regarding functional NYHA class, 1 (0.2%), 54(12%), 392 (87.1%), and 3 (0.7%) patients were class I, II, III, and IV, respectively. The lab investigations at first presentation were: mean HbA1C was 4.2 ± 0.6, and the mean of eGFR was 66.4 ± 9.3. Concerning Echocardiography data of patients LVEF by 2D echo show significant improvement from 34.73 ± 2.9 at baseline to 34.91 ± 1.2, 35.42 ± 3.5 & 36.54 ± 3.6 at 2, 4 & 6 months (P = 0.001) also GLS A4 showed significant improvement from −15.67 ± 2.74 to −16.5 ± 3.19, −17.32 ± 3.21, −18.03 ± 3.05at 2, 4 & 6 months (P = 0.001), and from −15.66 ± 2.65 to −16.50 ± 3.31, −17.41 ± 3.23 & −17.93 ± 3.32 (P = 0.001) by GLS A2 Regarding dapagliflozin LVEF by 2D echo show significant improvement from 34.87 ± 2.86 at baseline to 34.87 ± 2.86, 35.05 ± 3.01& 37.53 ± 4.1 at 2, 4 & 6 months (P = 0.001) also GLS A2 showed significant improvement from −15.67 ± 2.74 to −16.50 ± 3.31 −17.41 ± 3.23 −17.93 ± 3.32 at 2, 4 & 6 months (P = 0.001), and from −15.54 ± 2.77 to −16.84 ± 3.49, −18.48 ± 2.23 & −19.61 ± 2.98 (P = 0.001) by GLS A4, also E/e′ significantly reduced from 11.2 ± 2.7 to 9.1 ± 2.3 cm/s after administration of empagliflozin and dapagliflozin within 6 months (P = 0.01) also LAVI (ml/m2) improved from 45.6 ± 15.3 to 37.5 ± 6.5 (P = 0.001) after 6 month The results revealed a significant increase of ejection fraction at 4 and 6 months follow-up and a significant improvement of global longitudinal strain at 2, 4 & 6 months follow-up in patients given SGLT2i. Conclusion SGLT2i
背景&最近,降糖药钠-葡萄糖共转运蛋白2型抑制剂(SGLT2i)被批准为降低HFrEF患者死亡率的药物之一。SGLT2i抑制剂对心力衰竭(HF)患者左心室纵向心肌功能的影响尚不清楚。应用STE和传统超声心动图研究SGLT2i对HFrEF患者左室重构和功能的影响。目的应用超声心动图和超声心动图研究SGLT2i对HFrEF患者左室重构和功能的影响。方法对300例HFrEF患者进行分析。研究设计:这项前瞻性观察性研究纳入了300例hfref给药的SGLT2i(恩格列净;达格列净(Dapagliflozin))是治疗心衰的经典方法之一。然后对患者进行随访2,4 &治疗后6个月,实验室检查HbA1C和eGFR,并进行二维超声检查;STE的研究。结果人口统计学方面,男女平均年龄为50±9.2岁。平均体重(85.6±8.8 kg)、平均身高(178.6±7.2 cm)、平均体重指数(BMI)(26.6±2.9)。收缩压(SBP)为115.3±5.1,舒张压(DBP)为75.4±4.5。平均心率为79.9±10.2。平均呼吸频率为15±2.2。在功能性NYHA分类中,I、II、III、IV类患者分别为1例(0.2%)、54例(12%)、392例(87.1%)和3例(0.7%)。首次就诊时的实验室检查结果为:平均HbA1C为4.2±0.6,平均eGFR为66.4±9.3。患者LVEF二维超声心动图数据由基线时的34.73±2.9改善为34.91±1.2,35.42±3.5;36.54±3.6 at 2,4 &6个月(P = 0.001) GLS A4也有显著改善,从- 15.67±2.74到- 16.5±3.19,- 17.32±3.21,- 18.03±3.05at 2,4 &;6个月(P = 0.001),从−15.66±2.65到−16.50±3.31,−17.41±3.23;2D回声显示,达格列净LVEF由基线时的34.87±2.86显著改善至34.87±2.86,35.05±3.01;37.53±4.1 at 2,4 &6个月(P = 0.001), GLS A2在2,4 &时也从- 15.67±2.74显著改善到- 16.50±3.31 - 17.41±3.23 - 17.93±3.32;6个月(P = 0.001),从−15.54±2.77到−16.84±3.49,−18.48±2.23;在给药后6个月内,E/ E′从11.2±2.7降低到9.1±2.3 cm/s (P = 0.01), LAVI (ml/m2)从45.6±15.3提高到37.5±6.5 (P = 0.001)。结果显示,在随访4和6个月时,射血分数显著增加,在2、4和amp时,全球纵向应变显著改善;SGLT2i患者随访6个月。结论SGLT2i可改善左室纵向心肌功能,进一步改善左室舒张功能。SGLT2i与EF和LV纵向心肌功能增加有关。一个作者的视频,伴随着这个摘要可在https://academic.oup.com/eurheartjsupp。请点击“更多内容”旁边的箭头,然后点击“作者视频”。
{"title":"Assessment of cardiac functions using two-dimensional transthoracic and speckle tracking echocardiography after treatment with SGLT2 inhibitors in Patients with HFrEF","authors":"Amr Setouhi, Ashraf Radi, Hany Taha Asklany, Hazem M A Farrag","doi":"10.1093/eurheartjsupp/suad113.002","DOIUrl":"https://doi.org/10.1093/eurheartjsupp/suad113.002","url":null,"abstract":"Abstract Background &amp; objective Recently, the antidiabetic drug sodium-glucose cotransporter type 2 inhibitor (SGLT2i) has been approved among the drugs that reduce mortality in patients with HFrEF. The impact of SGLT2i inhibitors on the left ventricle longitudinal myocardial function in heart failure (HF) patients remained vague. The effect of SGLT2i on left ventricular remodeling and function in patients with HFrEF was studied using STE and traditional echocardiography. Objectives Studying the effects of SGLT2i on left ventricular remodeling and function in HFrEF patients using STE and traditional echocardiography. Methods 300 patients with HFrEF were included.Study design: This prospective observational study involves 300 patients with HFrEF-administered SGLT2i (Empagliflozin &amp; Dapagliflozin) in addition to the classical treatment of heart failure. Then the patients were followed up 2, 4 &amp; 6 months after treatment with laboratory investigations of HbA1C and eGFR, in addition to 2D echo &amp; STE studies. Results Regarding Demographic data, the mean age was 50 ± 9.2 for males and females. The mean weight, height, and body mass index (BMI) were 85.6 ± 8.8 kg, 178.6 ± 7.2 cm, and 26.6 ± 2.9, respectively. The systolic blood pressure (SBP) and diastolic blood pressure (DBP) were 115.3 ± 5.1 and 75.4 ± 4.5, respectively. The mean heart rate was 79.9 ± 10.2. The mean respiratory rate was15 ± 2.2. Regarding functional NYHA class, 1 (0.2%), 54(12%), 392 (87.1%), and 3 (0.7%) patients were class I, II, III, and IV, respectively. The lab investigations at first presentation were: mean HbA1C was 4.2 ± 0.6, and the mean of eGFR was 66.4 ± 9.3. Concerning Echocardiography data of patients LVEF by 2D echo show significant improvement from 34.73 ± 2.9 at baseline to 34.91 ± 1.2, 35.42 ± 3.5 &amp; 36.54 ± 3.6 at 2, 4 &amp; 6 months (P = 0.001) also GLS A4 showed significant improvement from −15.67 ± 2.74 to −16.5 ± 3.19, −17.32 ± 3.21, −18.03 ± 3.05at 2, 4 &amp; 6 months (P = 0.001), and from −15.66 ± 2.65 to −16.50 ± 3.31, −17.41 ± 3.23 &amp; −17.93 ± 3.32 (P = 0.001) by GLS A2 Regarding dapagliflozin LVEF by 2D echo show significant improvement from 34.87 ± 2.86 at baseline to 34.87 ± 2.86, 35.05 ± 3.01&amp; 37.53 ± 4.1 at 2, 4 &amp; 6 months (P = 0.001) also GLS A2 showed significant improvement from −15.67 ± 2.74 to −16.50 ± 3.31 −17.41 ± 3.23 −17.93 ± 3.32 at 2, 4 &amp; 6 months (P = 0.001), and from −15.54 ± 2.77 to −16.84 ± 3.49, −18.48 ± 2.23 &amp; −19.61 ± 2.98 (P = 0.001) by GLS A4, also E/e′ significantly reduced from 11.2 ± 2.7 to 9.1 ± 2.3 cm/s after administration of empagliflozin and dapagliflozin within 6 months (P = 0.01) also LAVI (ml/m2) improved from 45.6 ± 15.3 to 37.5 ± 6.5 (P = 0.001) after 6 month The results revealed a significant increase of ejection fraction at 4 and 6 months follow-up and a significant improvement of global longitudinal strain at 2, 4 &amp; 6 months follow-up in patients given SGLT2i. Conclusion SGLT2i ","PeriodicalId":11956,"journal":{"name":"European Heart Journal Supplements","volume":"89 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135299069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Deferred Stenting for Side Branch in STEMI Patients Presented by Bifurcation Culprit Lesion 以分叉罪魁病变为表现的STEMI患者侧支延期支架术
4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-09-01 DOI: 10.1093/eurheartjsupp/suad113.018
Mahmoud Tantawy, Sherif Hussien, Sameh Mosaad
Abstract Background True bifurcation lesions are challenging in some special populations like patients with heavily calcified vessels, unprotected left main, and thrombus-containing lesions. Multiple inflations are known to increase the incidence of no-reflow/slow-flow (NR/SL) during primary PCI. The ideal bifurcation stenting strategy during primary PCI is still obscure. Some studies have shown some benefits for deferred stenting in primary PCI but still this area needs more evidence. In our study, we compared deferred stenting for the side branch during primary PCI versus the complete bifurcation stenting strategy during primary PCI. Methods This is prospective observational study included patients who presented with STEMI due to true bifurcation culprit lesion amenable for two stents technique. Group one included patients with provisional stenting and deferred side branch stenting before hospital discharge. Group two included patients with complete two stents bifurcation technique during primary PCI. The technique used was according to operator discretion while patients with immediate indications for two stents strategy during the primary setting were excluded from our study. The primary outcome was MACE till hospital discharge. Secondary outcomes included angiographic outcomes by the end of the bifurcation technique. Results A total of 60 patients met our inclusion criteria, mean age (58.69±9.61), 31.2% women. Twenty-six patients received deferred stenting for side branch, and 34 received complete two stents bifurcation strategy at the primary PCI setting. MACE to hospital discharge was lower in the deferred stenting group without significant difference (21.62% vs 23.64%, P&gt;0.01] compared with the two-stenting approach during primary PCI. Group I (deferred stenting) had significantly superior angiographic outcomes than group II. As regards TIMI II-III flow, 86.2% of patients achieved it in both main vessel and side branch versus 51.1% in group II, CTFC was 8.1 versus 9.6, and in group I, 78% of patients achieved TMPG II-III, compared to 56.7% in group II. Conclusion Deferred stenting for side branch in primary PCI achieved superior angiographic outcomes in the treatment of true bifurcation lesions. However, there was no significant difference in MACE between both strategies.
在一些特殊人群中,如血管严重钙化、左主干未受保护和含血栓病变的患者,真正的分叉病变是具有挑战性的。多次充气已知会增加初次PCI期间无回流/慢流(NR/SL)的发生率。理想的分岔支架术在初级PCI仍然是模糊的策略。一些研究显示延迟支架置入术在初次PCI中有一些益处,但这一领域仍需要更多的证据。在我们的研究中,我们比较了初次PCI期间侧支延期支架置入与初次PCI期间完全分岔支架置入策略。方法:这是一项前瞻性观察性研究,纳入了因真分叉罪魁祸首病变可适用双支架技术而出现STEMI的患者。第一组包括出院前行临时支架术和延期侧支支架术的患者。第二组包括在初次PCI中采用完全双支架分岔技术的患者。所使用的技术是根据操作者的判断,而在最初设置时立即有两个支架策略指征的患者被排除在我们的研究之外。出院前主要观察指标为MACE。次要结果包括分岔技术结束时的血管造影结果。结果共60例患者符合纳入标准,平均年龄(58.69±9.61)岁,女性31.2%。26例患者接受了侧支延期支架术,34例患者在初次PCI设置时接受了完整的双支架术。初次PCI时延期支架置入组与双支架置入组相比,MACE较低,但无显著差异(21.62% vs 23.64%, P>0.01)。I组(延期支架置入术)的血管造影结果明显优于II组。关于TIMI II- iii型血流,86.2%的患者在主血管和侧支均达到,而II组为51.1%,CTFC为8.1比9.6,在I组中,78%的患者达到TMPG II- iii型,而II组为56.7%。结论原发性PCI侧支延期支架术治疗真分叉病变具有较好的血管造影效果。然而,两种策略间的MACE无显著差异。
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引用次数: 0
Study of mitral valve remodling in patients with atrial functional mitral valve regurgitation using three-dimensional echocardiography 心房功能性二尖瓣反流患者二尖瓣重构的三维超声心动图研究
4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-09-01 DOI: 10.1093/eurheartjsupp/suad113.015
Kawkab Khedr, Eman Elsharkawy, Hoda Shehata, Bassant Mowafy
Abstract Background The global burden of atrial fibrillation (AF) is enormous for healthcare systems. AF is typically classified into five distinct patterns depending on the onset, progression, and resolution of AF episodes, first diagnosed AF, paroxysmal AF, persistent AF, long-standing persistent AF& permanent AF. Atrial structural remodeling or exacerbation of atrial cardiomyopathy are generally defining features of the transition from paroxysmal to non-paroxysmal AF. The duration of rhythm monitoring and the presence of a substrate are both important factors in determining the rate of AF development. In the existence of a structurally normal valve, functional MR develops when there is a mismatch between the tethering forces exerted by the heart & the closing forces exerted by the heart. In the context of functional MR annular dilation alone, can constitute a separate etiology of MR (atrial functional MR). TEE provides supplementary imaging, particularly if TTE windows are technically challenging, making it a useful tool even if TTE is the primary technique for assessing and quantifying mitral valve disease. 3DE data sets can be acquired from either TTE or TEE approach, allowing real-time visualization of the cardiac structures, it is superior to 2DE in quantification of cardiac chamber volumes and function, assessment of the mechanisms and severity of heart valve diseases, evaluation of cardiac complex anatomy. Aim of the work To study mitral valve apparatus remodeling in patients with atrial functional mitral valve regurgitation using three-dimensional echocardiography. Methods This study included a total of 30 patients with diagnosis of atrial fibrillation divided in to two groups, 15 patients having no/ mild mitral regurgitation while 15 patients having moderate/severe mitral regurgitation, they were subjected to 2D and 3D TEE echocardiographic assessment of MR degree, LA volumes, mitral leaflets and mitral annulus parameters. Results There was statistically significant difference between the two groups as regard the posterior leaflet area as larger area was estimated in (Mod/severe MR) group compared to (No/ mild MR) group, with mean posterior leaflet area in group I was (8.96 ± 2.60) and (7.30 ± 2.17) in group II with (P value = 0.029) as well as there was statistically significant difference between the two groups as regard total leaflet area/Mitral annular area ratio as smaller ratio was estimated in (Mod/severe MR) group as compared to (No/mild MR) group, with the mean total leaflet area /mitral annular area ratio in group I was (1.22 ± 0.04) and (1.26 ± 0.04) in group II with (P value = 0.008). Conclusion Isolated annular dilatation can cause significant functional atrial mitral regurgitation while mitral leaflet area increases in AF as the annulus dilates, but this adaptation may plateau at larger annular areas, with the resulting leaflet deficiency causing functional atrial mitral regurgitation. Additional Content An author
背景房颤(AF)的全球负担是巨大的医疗保健系统。根据AF发作的发生、进展和消退,AF通常分为五种不同的类型:首次诊断AF、阵发性AF、持续性AF、长期持续性AF;永久性房颤。心房结构重构或心房心肌病加重通常是阵发性房颤向非阵发性房颤过渡的决定性特征。心律监测的持续时间和底物的存在都是决定房颤发展速度的重要因素。在结构正常的瓣膜存在的情况下,当心脏施加的栓系力之间存在不匹配时,功能性磁共振就会发展。心脏闭合力:由心脏施加的闭合力在功能性MR的背景下,单独的环形扩张可以构成单独的MR病因(心房功能性MR)。TEE提供了补充成像,特别是当TTE窗口在技术上具有挑战性时,即使TTE是评估和量化二尖瓣疾病的主要技术,TEE也是一种有用的工具。3DE数据集可以通过TTE或TEE方法获得,可以实时可视化心脏结构,在量化心腔容量和功能,评估心脏瓣膜疾病的机制和严重程度,评估心脏复杂解剖结构方面优于2DE。目的应用三维超声心动图研究心房功能性二尖瓣反流患者二尖瓣器官重构。方法将30例诊断为房颤的患者分为无/轻度二尖瓣反流患者15例和中度/重度二尖瓣反流患者15例,分别行二维和三维TEE超声心动图评估MR度、LA容积、二尖瓣小叶和二尖瓣环参数。结果两组后叶面积比较差异有统计学意义,(Mod/重度MR)组后叶面积较(No/轻度MR)组大;面积意味着后传单在我组(8.96±2.60)和(7.30±2.17)在第二组(P值= 0.029)以及在两组之间有显著差异,认为传单总面积/二尖瓣环面积比规模较小的比率估计(Mod)先生/严重组(无/轻度先生)组相比,平均传单总面积/二尖瓣环面积比在我组(1.22±0.04)和(1.26±0.04)在第二组(P值= 0.008)。结论孤立心房环扩张可引起心房二尖瓣明显的功能性返流,心房环扩张时二尖瓣小叶面积增加,但这种适应可能在心房环扩大时趋于平稳,导致小叶不足导致心房二尖瓣功能性返流。一个作者的视频,伴随着这个摘要可在https://academic.oup.com/eurheartjsupp。请点击“更多内容”旁边的箭头,然后点击“作者视频”。
{"title":"Study of mitral valve remodling in patients with atrial functional mitral valve regurgitation using three-dimensional echocardiography","authors":"Kawkab Khedr, Eman Elsharkawy, Hoda Shehata, Bassant Mowafy","doi":"10.1093/eurheartjsupp/suad113.015","DOIUrl":"https://doi.org/10.1093/eurheartjsupp/suad113.015","url":null,"abstract":"Abstract Background The global burden of atrial fibrillation (AF) is enormous for healthcare systems. AF is typically classified into five distinct patterns depending on the onset, progression, and resolution of AF episodes, first diagnosed AF, paroxysmal AF, persistent AF, long-standing persistent AF&amp; permanent AF. Atrial structural remodeling or exacerbation of atrial cardiomyopathy are generally defining features of the transition from paroxysmal to non-paroxysmal AF. The duration of rhythm monitoring and the presence of a substrate are both important factors in determining the rate of AF development. In the existence of a structurally normal valve, functional MR develops when there is a mismatch between the tethering forces exerted by the heart &amp; the closing forces exerted by the heart. In the context of functional MR annular dilation alone, can constitute a separate etiology of MR (atrial functional MR). TEE provides supplementary imaging, particularly if TTE windows are technically challenging, making it a useful tool even if TTE is the primary technique for assessing and quantifying mitral valve disease. 3DE data sets can be acquired from either TTE or TEE approach, allowing real-time visualization of the cardiac structures, it is superior to 2DE in quantification of cardiac chamber volumes and function, assessment of the mechanisms and severity of heart valve diseases, evaluation of cardiac complex anatomy. Aim of the work To study mitral valve apparatus remodeling in patients with atrial functional mitral valve regurgitation using three-dimensional echocardiography. Methods This study included a total of 30 patients with diagnosis of atrial fibrillation divided in to two groups, 15 patients having no/ mild mitral regurgitation while 15 patients having moderate/severe mitral regurgitation, they were subjected to 2D and 3D TEE echocardiographic assessment of MR degree, LA volumes, mitral leaflets and mitral annulus parameters. Results There was statistically significant difference between the two groups as regard the posterior leaflet area as larger area was estimated in (Mod/severe MR) group compared to (No/ mild MR) group, with mean posterior leaflet area in group I was (8.96 ± 2.60) and (7.30 ± 2.17) in group II with (P value = 0.029) as well as there was statistically significant difference between the two groups as regard total leaflet area/Mitral annular area ratio as smaller ratio was estimated in (Mod/severe MR) group as compared to (No/mild MR) group, with the mean total leaflet area /mitral annular area ratio in group I was (1.22 ± 0.04) and (1.26 ± 0.04) in group II with (P value = 0.008). Conclusion Isolated annular dilatation can cause significant functional atrial mitral regurgitation while mitral leaflet area increases in AF as the annulus dilates, but this adaptation may plateau at larger annular areas, with the resulting leaflet deficiency causing functional atrial mitral regurgitation. Additional Content An author","PeriodicalId":11956,"journal":{"name":"European Heart Journal Supplements","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135298358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pattern of cardiovascular admission diagnoses during the month of Ramadan: a single center experience 斋月期间心血管入院诊断模式:单一中心经验
4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-09-01 DOI: 10.1093/eurheartjsupp/suad113.012
Hesham S Taha, Ghada Youssef, Mirna M Shaker, Mohamed Ghalab, Hadeer G Sayed, Suzan H Abdullah, Mohamed A Thabet, Amir Mostafa
Abstract Background Fasting Ramadan has been linked to favorable health profile, yet some unhealthy behaviors were shown to affect the progression of cardiovascular diseases during the holy month. Purpose To detect the prevalent diagnoses of cardiovascular admissions during the month of Ramadan and to compare them to the admission diagnoses during the rest of the year. Methods This retrospective observational study included all patients who were admitted to the Cardiology department and the Coronary Care Unit from April 2019 to May 2022, with 4 Ramadan months included. The median number of specific cardiac admission diagnoses during Ramadan months were compared to the median number of similar admission diagnoses during the other months of the year. Results The number of patients admitted during the 4 year-study period were 8170 patients, 14.6% of them (n = 1194 patients) were admitted during the 4 Ramadan months. All cardiovascular diagnoses were comparable during Ramadan admissions as compared to the rest of the year, Table. There was a trend towards higher cardiovascular admission rates during Ramadan in almost all diagnoses except for unstable angina, infective endocarditis and pericardial diseases. Conclusions The pattern of specific cardiovascular disease admission during Ramadan was not different from the pattern of admission during the rest of the year. Yet, there were numerically higher cardiovascular admissions during the 4 Ramadan months. Table Comparison of the median number of admission diagnoses in the 4 Ramadan months and the monthly average of the 4 years Ramadan months Median (range) Monthly average of the 4 years Median (range) P value IHD 145.5 (63) 106 (74) 0.486 * CCS 39.5 (35) 17 (11) 0.057 * ACS 107.5 (71) 89 (83) 0.686 - STEMI 49.5 (34) 39 (24) 0.343 - NSTEMI 41 (46) 39.5 (56) 1.0 - UA 8.5 (8) 10 (4) 0.686 ADHF & cardiogenic shock 113.5 (111) 56 (37) 0.486 Arrhythmia 43.5 (39) 34 (10) 0.343 - AF 18.5 (22) 22.5 (5) 0.686 - SVT 9.5 (15) 6 (9) 0.486 - AFL 6 (12) 2.5 (2) 0.2 - CHB 4 (5) 3.5 (3) 0.686 IE 10.5 (7) 14 (6) 0.2 PE 3 (11) 2.5 (1) 0.686 Pericardial disease 2 (6) 6 (11) 0.2 Hypertensive urgency & emergency 12 (23) 9.5 (7) 1.0 IHD, ischemic heart disease; CCS, chronic coronary syndrome; ACS, acute coronary syndrome; STEMI, ST elevation myocardial infarction; NSTEMI, non-ST elevation myocardial infarction; UA, unstable angina; ADHF, acute decompensated heart failure; AF, atrial fibrillation; SVT, supraventricular tachycardia; AFL, atrial flutter; CHD, complete heart block; IE, infective endocarditis; PE, pulmonary embolism. Additional Content An author video to accompany this abstract is available on https://academic.oup.com/eurheartjsupp. Please click on the arrow next to ‘More Content’ and then click on ‘Author videos’.
斋月与良好的健康状况有关,但一些不健康的行为被证明会影响斋月期间心血管疾病的进展。目的了解斋月期间心血管住院的流行诊断率,并将其与全年其他时间的住院诊断率进行比较。方法回顾性观察性研究纳入2019年4月至2022年5月在心内科和冠状动脉监护室住院的所有患者,其中包括4个斋月。将斋月期间特定心脏入院诊断的中位数与一年中其他月份类似入院诊断的中位数进行比较。结果4年研究期间入院患者8170例,其中14.6%(1194例)在斋月期间入院。所有心血管诊断在斋月入院期间与一年中其他时间相比具有可比性,表。除了不稳定型心绞痛、感染性心内膜炎和心包疾病外,斋月期间几乎所有诊断的心血管入院率都有上升趋势。结论斋月期间特定心血管疾病的住院模式与其他时间的住院模式无明显差异。然而,在4个斋月期间,心血管入院人数更高。表斋月4个月入院诊断数中位数与斋月4年月平均诊断数中位数(范围)4年月平均诊断数中位数(范围)P值IHD 145.5 (63) 106 (74) 0.486 * CCS 39.5 (35) 17 (11) 0.057 * ACS 107.5 (71) 89 (83) 0.686 - STEMI 49.5 (34) 39 (24) 0.343 - NSTEMI 41 (46) 39.5 (56) 1.0 - UA 8.5 (8) 10 (4) 0.686 ADHF &心源性休克113.5(111)56(37)0.486心律失常43.5 (39)34 (10)0.343 - AF 18.5 (22) 22.5 (5) 0.686 - SVT 9.5 (15) 6 (9) 0.486 - AFL 6 (12) 2.5 (2) 0.2 - chb4 (5) 3.5 (3) 0.686 IE 10.5 (7) 14 (6) 0.2 PE 3(11) 2.5(1) 0.686心包疾病2(6)6(11)0.2高血压急症&急诊12 (23)9.5 (7)1.0 IHD,缺血性心脏病;慢性冠状动脉综合征;ACS,急性冠脉综合征;STEMI, ST段抬高型心肌梗死;NSTEMI,非st段抬高型心肌梗死;UA,不稳定型心绞痛;ADHF,急性失代偿性心力衰竭;AF,心房颤动;SVT,室上性心动过速;AFL,心房扑动;CHD,完全性心脏传导阻滞;IE,感染性心内膜炎;PE,肺栓塞。一个作者的视频,伴随着这个摘要可在https://academic.oup.com/eurheartjsupp。请点击“更多内容”旁边的箭头,然后点击“作者视频”。
{"title":"Pattern of cardiovascular admission diagnoses during the month of Ramadan: a single center experience","authors":"Hesham S Taha, Ghada Youssef, Mirna M Shaker, Mohamed Ghalab, Hadeer G Sayed, Suzan H Abdullah, Mohamed A Thabet, Amir Mostafa","doi":"10.1093/eurheartjsupp/suad113.012","DOIUrl":"https://doi.org/10.1093/eurheartjsupp/suad113.012","url":null,"abstract":"Abstract Background Fasting Ramadan has been linked to favorable health profile, yet some unhealthy behaviors were shown to affect the progression of cardiovascular diseases during the holy month. Purpose To detect the prevalent diagnoses of cardiovascular admissions during the month of Ramadan and to compare them to the admission diagnoses during the rest of the year. Methods This retrospective observational study included all patients who were admitted to the Cardiology department and the Coronary Care Unit from April 2019 to May 2022, with 4 Ramadan months included. The median number of specific cardiac admission diagnoses during Ramadan months were compared to the median number of similar admission diagnoses during the other months of the year. Results The number of patients admitted during the 4 year-study period were 8170 patients, 14.6% of them (n = 1194 patients) were admitted during the 4 Ramadan months. All cardiovascular diagnoses were comparable during Ramadan admissions as compared to the rest of the year, Table. There was a trend towards higher cardiovascular admission rates during Ramadan in almost all diagnoses except for unstable angina, infective endocarditis and pericardial diseases. Conclusions The pattern of specific cardiovascular disease admission during Ramadan was not different from the pattern of admission during the rest of the year. Yet, there were numerically higher cardiovascular admissions during the 4 Ramadan months. Table Comparison of the median number of admission diagnoses in the 4 Ramadan months and the monthly average of the 4 years Ramadan months Median (range) Monthly average of the 4 years Median (range) P value IHD 145.5 (63) 106 (74) 0.486 * CCS 39.5 (35) 17 (11) 0.057 * ACS 107.5 (71) 89 (83) 0.686 - STEMI 49.5 (34) 39 (24) 0.343 - NSTEMI 41 (46) 39.5 (56) 1.0 - UA 8.5 (8) 10 (4) 0.686 ADHF &amp; cardiogenic shock 113.5 (111) 56 (37) 0.486 Arrhythmia 43.5 (39) 34 (10) 0.343 - AF 18.5 (22) 22.5 (5) 0.686 - SVT 9.5 (15) 6 (9) 0.486 - AFL 6 (12) 2.5 (2) 0.2 - CHB 4 (5) 3.5 (3) 0.686 IE 10.5 (7) 14 (6) 0.2 PE 3 (11) 2.5 (1) 0.686 Pericardial disease 2 (6) 6 (11) 0.2 Hypertensive urgency &amp; emergency 12 (23) 9.5 (7) 1.0 IHD, ischemic heart disease; CCS, chronic coronary syndrome; ACS, acute coronary syndrome; STEMI, ST elevation myocardial infarction; NSTEMI, non-ST elevation myocardial infarction; UA, unstable angina; ADHF, acute decompensated heart failure; AF, atrial fibrillation; SVT, supraventricular tachycardia; AFL, atrial flutter; CHD, complete heart block; IE, infective endocarditis; PE, pulmonary embolism. Additional Content An author video to accompany this abstract is available on https://academic.oup.com/eurheartjsupp. Please click on the arrow next to ‘More Content’ and then click on ‘Author videos’.","PeriodicalId":11956,"journal":{"name":"European Heart Journal Supplements","volume":"77 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135298841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Determinants of left atrial stiffness by reservoir strain using 2D speckle tracking echocardiography in structurally normal heart 在结构正常的心脏中,用二维斑点跟踪超声心动图判断左心房僵硬度的决定因素
4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-09-01 DOI: 10.1093/eurheartjsupp/suad113.003
Aya Tarek Elsayegh, Osama Mohameden Mohamed Asous, Ahmed Mohamed El misiri
Abstract Introduction The left atrium (LA)’s essential function is modulating left ventricular (LV) filling via its different reservoir, conduit, and contractile functions. This could be accurately achieved now by dedicated speckle-tracking echocardiography software. Methodology We included in this prospective cohort study 200 subjects with structurally normal hearts, who present for elective echocardiography, routine echocardiography was performed in addition to left atrial strain analysis by 2D speckle tracking echocardiography. Aim of work To study the effect of different variables on left atrial reservoir strain. Results The study population consisted of 134 males and 66 females, age range between 20 and 69 years of age. linear regression analysis was performed to examine the contributions of different variables as predictors in explaining the variance. S-R (strain reservoir) was significantly affected by age in a negative correlation with P = 0.032. Body weight, height, BMI (body mass index), lipid profile and HbA1C (glycosylated hemoglobin) had no significant impact on S-R left atrial function. All echocardiographic parameters of diastolic function including E/A ratio, Septal E′, Lateral E′, E/E′ and TR jet velocity had no significant impact on S-R left atrial function. Maximum and minimum indexed left atrial volumes, indexed LV systolic and diastolic volumes measured by Simpson’s method had no significant effect on S-R left atrial function. Conclusion Left atrial stiffness increases with age. Obesity, dyslipidemia, impaired glucose tolerance and diastolic dysfunction have no significant effect on the S-R of the left atrium. Additional Content An author video to accompany this abstract is available on https://academic.oup.com/eurheartjsupp. Please click on the arrow next to ‘More Content’ and then click on ‘Author videos’.
左心房(LA)的基本功能是通过其不同的储血功能、传导功能和收缩功能来调节左心室(LV)充盈。这可以通过专门的斑点跟踪超声心动图软件准确地实现。本前瞻性队列研究纳入了200例心脏结构正常的患者,他们接受了选择性超声心动图检查,常规超声心动图检查以及二维斑点跟踪超声心动图左心房应变分析。研究不同变量对左心房贮液应变的影响。结果研究人群男性134人,女性66人,年龄在20 ~ 69岁之间。采用线性回归分析检验不同变量作为预测因子对解释方差的贡献。S-R(菌株库)受年龄影响显著,呈负相关(P = 0.032)。体重、身高、BMI(身体质量指数)、血脂和糖化血红蛋白(HbA1C)对S-R左房功能无显著影响。舒张功能超声心动图参数E/A比、室间隔E′、侧位E′、E/E′、TR射流速度对S-R左房功能无显著影响。辛普森法测定的最大、最小左房指数化容积、左室收缩、舒张指数化容积对S-R左房功能无显著影响。结论左心房僵硬度随年龄增长而增加。肥胖、血脂异常、糖耐量降低、舒张功能不全对左心房S-R无显著影响。一个作者的视频,伴随着这个摘要可在https://academic.oup.com/eurheartjsupp。请点击“更多内容”旁边的箭头,然后点击“作者视频”。
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引用次数: 0
Logistic regression vs. linear regression in exploring the importance of health literacy for the quality of life of patients with heart failure Logistic回归与线性回归探讨健康素养对心力衰竭患者生活质量的重要性
4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-09-01 DOI: 10.1093/eurheartjsupp/suad113.010
Reham M Nagaty, Mona Hassan Ahmed, Amany M Seddik, Ahmed Abdelaty, Laila Mohamed Hamed Nofal
Abstract Methods A cross sectional study was conducted among 200 heart failure patients selected from two hospitals in Alexandria governate. The HLS-EU-Q16 survey to assess HL, SF-12 health survey questionnaire to assess QoL, record review, and interviewing the patients were used to collect the required data. Linear and logistic regression models were used to explore the relation between health literacy and the QoL then comparing between the two models. Results Forty-six and half percent of HF patients had sufficient HL while 53.5% had insufficient HL. Patients showed low mean score of 34.16 ± 10.43 for the physical dimension of the SF-12 questionnaire (PCS-12), while the mental dimension (MCS-12) displayed good mean score of 41.87 ± 14.34. For the linear regression regarding PCS-12, HL was statistically significant and an independent predictor of PCS-12 in patients with HF, both before and after adjustment for the personal and clinical characteristics. Concerning MCS-12, we found that HL was statistically significant and an independent predictor of MCS-12 only before adjustment. While in logistic regression, considering PCS-12, analysis revealed that HL was not statistically significant predictor of the median-split dichotomized PCS-12 in both before and after adjustments for covariates. Regarding MCS-12, it was found that HL was statistically significant and an independent predictor of the median-split dichotomized MCS-12 only before adjustment for personal and clinical characteristics. The correct prediction percent in the logistic model of PCS-12 (70%) was higher than the linear model (53.5%). Similarly, the correct prediction percent in the logistic model of MCS-12 (68.5%) was higher than the linear model (57.5%). Conclusion It has been explained that HL is a statistically significant independent predictor of only the PCS-12 of SF-12 in the linear regression model but not for MCS-12, while it was not statistically significant predictor in the logistic models for the two dimensions of SF-12. However, each of the two models, linear regression model and logistic regression model, has its advantages and disadvantages.
方法对亚历山大省两家医院的200例心力衰竭患者进行横断面研究。采用HLS-EU-Q16问卷评估HL, SF-12健康调查问卷评估生活质量,记录回顾和患者访谈收集所需数据。采用线性和逻辑回归模型探讨健康素养与生活质量的关系,并对两种模型进行比较。结果46.5%的HF患者有足够的HL, 53.5%的HF患者有不足的HL。SF-12问卷(PCS-12)生理维度得分较低,平均为34.16±10.43分;心理维度得分较好,平均为41.87±14.34分。对于PCS-12的线性回归,在调整个人和临床特征前后,HL均具有统计学意义,是HF患者PCS-12的独立预测因子。对于MCS-12,我们发现HL仅在调整前具有统计学意义,是MCS-12的独立预测因子。而在logistic回归中,考虑到PCS-12,分析显示HL在协变量调整前后均不是中位数分裂二分化PCS-12的统计学显著预测因子。对于MCS-12,我们发现HL仅在调整个人和临床特征之前具有统计学意义,并且是MCS-12中位数分裂二分的独立预测因子。PCS-12 logistic模型的预测正确率(70%)高于线性模型(53.5%)。同样,MCS-12 logistic模型的预测正确率(68.5%)高于线性模型(57.5%)。结论HL在线性回归模型中仅是SF-12的PCS-12的独立预测因子,而对MCS-12的独立预测因子无统计学意义,而在SF-12的两个维度的logistic模型中无统计学意义。然而,线性回归模型和逻辑回归模型这两种模型各有优缺点。
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引用次数: 0
Stenting the unprotected left main coronary artery- mid-term outcomes of the observational registry 无保护的左冠状动脉主干支架术——观察登记的中期结果
4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-09-01 DOI: 10.1093/eurheartjsupp/suad113.013
Samir Rafla, Amr Zaki, Mohamed Loutfi, Mohamed Ahmed Sadaka, Moataz Shebl
Abstract Background New imaging modalities such as IVUS had improved results of Stenting of the unprotected left main coronary artery (UPLM). The results of stenting UPLM without these new modalities but with meticulous care need to be studied more. Methods This prospective and retrospective study was performed in multiple local centers. The local ethics committee approved the study, and the patients signed informed consent. In addition, the local heart team, including a cardiac surgeon, was consulted for a joint decision agreement. In the last five years, one hundred twenty patients with left main disease &gt;50% were subjected to stenting with drug- eluted stents.All patients were subjected to detailed history taking with particular emphasis on acute coronary syndrome, angina duration, class, previous coronary interventions, and medications. In addition, 12 lead ECGs were revised with an evaluation of ST/T changes and any old infarction. An echocardiographic examination was done on all patients. Relevant laboratory tests were done.Risk assessment was calculated for every patient, including Euro SCORE and Syntax score. Patient selection: Consecutive patients arriving for primary Stenting or acute coronary episode were included. Medications: All patients received clopidogrel and aspirin before the planned procedure. Anticoagulation with unfractionated heparin in a dose of 10000 IU was given at the beginning of the PCI. Post PCI, all patients received B blockers, ACE inhibitors, statins, and dual antiplatelets in the guidelines recommended doses. Calcification was assessed by angiographic imaging only. We estimated the vessel diameter as 2/3 diameter of the branches. PCI technique: A steerable guidewire was advanced in LAD, followed by PCI with pre-dilatation or direct Stenting according to the operator’s discretion. One or two stent strategy was utilized according to the situation of the lesions. Results 92 patients (77.3%) presented with ACS, of which 65 patients (54.6%) had no Previous Intervention, and 27 patients (22.7%) had a previous PCI. Left ventricular ejection fraction significantly correlates with the complication at six months follow-up; all 16 patients with reported complications (100%) had baseline LVEF of &lt;40% (P-value = 0.023). Syntax score 11 patients (55%) with a high score of more than 32 had adverse events, P = 0.004. Residual syntax shows a less significant correlation with a mean value of 7.3 in the complication group vs. 4.9 in the other group (P = 0.016). Final kissing balloon inflation shows no statistically significant difference. Conclusions PCI in UPLM is a safe, feasible option with a high technical success rate and acceptable outcome at follow-up, even without the utilization of IVUS
背景IVUS等新的成像方式改善了无保护的冠状动脉左主干(UPLM)支架术的效果。在没有这些新模式的情况下,在精心护理的情况下支架置入UPLM的结果需要更多的研究。方法在多个地方中心进行前瞻性和回顾性研究。当地伦理委员会批准了这项研究,患者签署了知情同意书。此外,还咨询了当地的心脏小组,包括一名心脏外科医生,以达成共同决定协议。在过去的五年中,120例左主干疾病患者(50%)接受了药物洗脱支架置入术。所有患者都有详细的病史,特别强调急性冠状动脉综合征、心绞痛持续时间、类别、既往冠状动脉介入治疗和药物治疗。此外,对12例导联心电图进行修改,评估ST/T变化和任何旧梗死。所有患者均行超声心动图检查。进行了相关的实验室测试。对每位患者进行风险评估,包括Euro SCORE和Syntax评分。患者选择:连续接受支架置入术或急性冠状动脉发作的患者被纳入。药物治疗:所有患者在计划手术前都接受了氯吡格雷和阿司匹林。在PCI开始时给予10000 IU的肝素抗凝治疗。PCI后,所有患者均接受指南推荐剂量的B受体阻滞剂、ACE抑制剂、他汀类药物和双重抗血小板药物治疗。钙化仅通过血管造影评估。我们估计血管直径为分支直径的2/3。PCI技术:在LAD中使用可操纵导丝,然后根据操作者的判断进行PCI预扩张或直接支架置入。根据病变情况采用一种或两种支架置入策略。结果92例(77.3%)患者出现ACS,其中65例(54.6%)患者既往无干预,27例(22.7%)患者既往行PCI。随访6个月时左室射血分数与并发症显著相关;所有16例报告并发症的患者(100%)基线LVEF为40% (p值= 0.023)。句法评分较高的患者有11例(55%)出现不良事件,评分超过32分,P = 0.004。残差语法的相关性不太显著,并发症组的平均值为7.3,而另一组为4.9 (P = 0.016)。最终接吻气球膨胀没有统计学上的显著差异。结论PCI是一种安全可行的选择,技术成功率高,随访结果可接受,即使不使用IVUS
{"title":"Stenting the unprotected left main coronary artery- mid-term outcomes of the observational registry","authors":"Samir Rafla, Amr Zaki, Mohamed Loutfi, Mohamed Ahmed Sadaka, Moataz Shebl","doi":"10.1093/eurheartjsupp/suad113.013","DOIUrl":"https://doi.org/10.1093/eurheartjsupp/suad113.013","url":null,"abstract":"Abstract Background New imaging modalities such as IVUS had improved results of Stenting of the unprotected left main coronary artery (UPLM). The results of stenting UPLM without these new modalities but with meticulous care need to be studied more. Methods This prospective and retrospective study was performed in multiple local centers. The local ethics committee approved the study, and the patients signed informed consent. In addition, the local heart team, including a cardiac surgeon, was consulted for a joint decision agreement. In the last five years, one hundred twenty patients with left main disease &amp;gt;50% were subjected to stenting with drug- eluted stents.All patients were subjected to detailed history taking with particular emphasis on acute coronary syndrome, angina duration, class, previous coronary interventions, and medications. In addition, 12 lead ECGs were revised with an evaluation of ST/T changes and any old infarction. An echocardiographic examination was done on all patients. Relevant laboratory tests were done.Risk assessment was calculated for every patient, including Euro SCORE and Syntax score. Patient selection: Consecutive patients arriving for primary Stenting or acute coronary episode were included. Medications: All patients received clopidogrel and aspirin before the planned procedure. Anticoagulation with unfractionated heparin in a dose of 10000 IU was given at the beginning of the PCI. Post PCI, all patients received B blockers, ACE inhibitors, statins, and dual antiplatelets in the guidelines recommended doses. Calcification was assessed by angiographic imaging only. We estimated the vessel diameter as 2/3 diameter of the branches. PCI technique: A steerable guidewire was advanced in LAD, followed by PCI with pre-dilatation or direct Stenting according to the operator’s discretion. One or two stent strategy was utilized according to the situation of the lesions. Results 92 patients (77.3%) presented with ACS, of which 65 patients (54.6%) had no Previous Intervention, and 27 patients (22.7%) had a previous PCI. Left ventricular ejection fraction significantly correlates with the complication at six months follow-up; all 16 patients with reported complications (100%) had baseline LVEF of &amp;lt;40% (P-value = 0.023). Syntax score 11 patients (55%) with a high score of more than 32 had adverse events, P = 0.004. Residual syntax shows a less significant correlation with a mean value of 7.3 in the complication group vs. 4.9 in the other group (P = 0.016). Final kissing balloon inflation shows no statistically significant difference. Conclusions PCI in UPLM is a safe, feasible option with a high technical success rate and acceptable outcome at follow-up, even without the utilization of IVUS","PeriodicalId":11956,"journal":{"name":"European Heart Journal Supplements","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135299051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of e-portfolios on developing professional awareness for cardiac nurses 电子档案对培养心内科护士专业意识的影响
4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-09-01 DOI: 10.1093/eurheartjsupp/suad113.006
Mohamed El-Khatib, Ibrahim Helmy
Abstract Introduction Professional electronic portfolios are becoming increasingly popular among nurses as a means of documenting their lifelong learning and self-reflection, as well as proving that they have fulfilled all of their licensure and certification criteria. An e-Portfolio can help nurses keep track of their renewal and registration paperwork in one location so that they can be updated and used in performance assessments and job applications. All nurses are obliged to participate in continuing professional development activities in order to maintain, update, and to improve their knowledge and practice. In addition, e-Portfolios allow nurses to assess their strengths and weaknesses. Also, establishing an e-Portfolio can help nurses develop a learning strategy to meet those needs. Aim To assess the nurses' feedback after developing their professional e-Portfolio. Process As part of their professional development, nurses at the Aswan Heart Centre were required to compile their professional development records. Even the most recent curriculum vitae (CV) was difficult for most nurses to locate.Using Google sites as the e-platform, the nursing education department established a method for generating the e-Portfolio in a systematic manner. The e-Portfolio contained all of the following dataset (Biography—CV—Nursing, leadership, or teaching philosophy—Teaching Perspective Inventory Result—Learning Style Result—Personality Type—Conflict Style—Strength, Weaknesses, Opportunities, and Threats (SWOT) Analysis—Learning Action Plan—Professional Certificates—Research Activities).A brief guide was developed to assist nurses in developing the e-Portfolio to the same criteria. In addition, short courses were designed to assist them in creating a SWOT analysis and learning action plan. Survey Result There were 130 nurses who joined the process, and 70 nurses filled out the survey. What was the best part of creating your e-Portfolio?The majority of the staff members responded that they do collect their professional development records.What was the worst part of creating your e-Portfolio?The staff's biggest challenge during the platform’s development was time. Data Analysis Participants responded that use of the e-portfolio was a way to keep track of their own professional growth and gain a better understanding of who they are as well as help develop their professional identity as lifelong learners by approximately 70%.According to the responses from the participants, using the e-portfolio was a technique to boost their level of creativity as well as their level of proficiency with computer skills by around 65%. Recommendations Building and maintaining an e-Portfolio can also provide nurses with the ability to assess their skills and determine areas in which they require additional training, as well as to create a lifelong learning plan to meet these needs. Additional Content An author video to accompany this abstract is available on https://academic.oup.c
专业电子档案在护士中越来越受欢迎,作为记录他们终身学习和自我反思的一种手段,以及证明他们已经完成了所有的执照和认证标准。电子档案可以帮助护士在一个地方跟踪他们的更新和注册文件,以便他们可以更新并用于绩效评估和工作申请。所有护士都有义务参加持续的专业发展活动,以保持、更新和提高他们的知识和实践。此外,电子档案使护士能够评估自己的优势和劣势。此外,建立电子档案可以帮助护士制定学习策略来满足这些需求。目的了解护士建立专业电子档案后的反馈情况。作为专业发展的一部分,阿斯旺心脏中心的护士需要编制专业发展记录。即使是最近的简历(CV)对大多数护士来说也很难找到。护理教育部门以Google网站为电子平台,建立了系统生成电子档案的方法。电子档案包含以下所有数据集(个人简介-简历-护理、领导或教学理念-教学观点调查结果-学习风格结果-性格类型-冲突风格-优势、劣势、机会和威胁(SWOT)分析-学习行动计划-专业证书-研究活动)。制定了一份简短指南,以帮助护士根据相同的标准开发电子档案。此外,短期课程旨在帮助他们创建SWOT分析和学习行动计划。有130名护士参与了调查过程,70名护士填写了调查问卷。创建你的电子作品集最好的部分是什么?大多数工作人员回答说,他们确实收集了他们的专业发展记录。创建电子文件夹最糟糕的部分是什么?在平台开发过程中,员工面临的最大挑战是时间。数据分析参与者回应说,使用电子档案是一种跟踪自己的专业发展,更好地了解自己的方式,并帮助他们发展终身学习者的职业身份,约占70%。根据参与者的反应,使用电子档案是一种提高创造力水平和计算机技能熟练程度的技术,提高了约65%。建立和维护电子档案还可以使护士有能力评估自己的技能,确定需要额外培训的领域,并制定终身学习计划以满足这些需求。一个作者的视频,伴随着这个摘要可在https://academic.oup.com/eurheartjsupp。请点击“更多内容”旁边的箭头,然后点击“作者视频”。
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European Heart Journal Supplements
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