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A Case of Mosaic Down Syndrome 马赛克唐氏综合症一例
Pub Date : 2009-07-23 DOI: 10.3329/BJPATH.V24I1.2880
S. Habib
Cytogenetic analysis in 44 clinically suspected cases of Down syndrome (DS) was carried out using conventional Giemsa-trypsin-banding technique. Among them 43 cases were cytogenetically proved as DS. Forty-two individuals (97.7%) exhibited pure trisomy 21. The remaining child was a seven years old boy, the second-born of nonconsanguineous parents and had 46/47XY, +21 mosaicism. He also possessed most of the phenotypic characteristics of the classical trisomy 21.
采用常规giemsa -胰蛋白酶带带技术对44例临床疑似唐氏综合征(DS)患者进行细胞遗传学分析。其中43例细胞遗传学证实为退行性痴呆。纯种21三体42例(97.7%)。剩下的孩子是一个七岁的男孩,他是非近亲出生的第二个孩子,有46/47XY, +21马赛克。他还具有典型21三体的大部分表型特征。
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引用次数: 1
Cardio specific Troponin I in patients with Aortic stenosis 主动脉瓣狭窄患者的心肌特异性肌钙蛋白I
Pub Date : 2009-07-23 DOI: 10.3329/BJPATH.V24I1.2875
N. Nahar, B. Begum, Khaleque-uzzaman, S. Mashud, S. Parveen, R. Yeasmin
To evaluate the association of Cardio specific Troponin I (CTnI) and aortic stenosis. Cross sectional study was conducted among 20 aortic stenosis patients and 20 control groups. A structured questioner and checklist was used to collect data through face to face interview, Echocardiography findings, and laboratory estimation of cTnl. A total 20 patients and 20 healthy control subjects were investigated for cTnl. cTnl level was within normal physiological limits in all the control subjects. The mean value was 0.02±00. The mean cTnl level in Aortic stenosis patients were 0.67±0.81. EJection fraction of Aortic stenosis patients were normal, indicating that cases yet not develops complication (eg; Heart failure). The cTnl in control group and Aortic stenosis patients shows significant difference of mean (p < 0.001). cTnl level in Aortic stenosis patients increases in absence of heart failure indicating that it can expose cardiomyocyte injury prior to the development of over Left ventricular dysfunction. So that, serial monitoring of cTnl could help clinician to give definitive treatment before development of complications. Keywords: Cardiospecific Troporin I. Aortic Stenosis. doi: 10.3329/bjpath.v24i1.2875 Bangladesh J Pathol 24 (1) : 9-11
评价心肌特异性肌钙蛋白I (CTnI)与主动脉瓣狭窄的关系。对20例主动脉瓣狭窄患者和20例对照组进行横断面研究。采用结构化的提问者和检查表,通过面对面访谈、超声心动图结果和实验室估计cTnl来收集数据。共对20例患者和20例健康对照者进行cTnl检测。对照组cTnl水平均在正常生理范围内。平均值为0.02±00。主动脉瓣狭窄患者的平均cTnl水平为0.67±0.81。主动脉瓣狭窄患者射血分数正常,提示未发生并发症(如;心力衰竭)。对照组与主动脉瓣狭窄患者的cTnl均值差异有统计学意义(p < 0.001)。主动脉瓣狭窄患者的cTnl水平在无心力衰竭的情况下升高,表明它可以在左心室功能障碍发展之前暴露心肌细胞损伤。因此,对cTnl的连续监测可以帮助临床医生在并发症发生前给予明确的治疗。关键词:心脏特异性Troporin;主动脉瓣狭窄;doi: 10.3329/bjpath.v24i1.2875孟加拉国病理学杂志24 (1):9-11
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引用次数: 0
Safe Blood Transfusion: Past, Present And Future 安全输血:过去、现在和未来
Pub Date : 2009-07-23 DOI: 10.3329/BJPATH.V24I1.2873
T. Dipta, Tahminur Rahman
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引用次数: 5
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Bangladesh Journal of Pathology
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