Pub Date : 2022-11-21DOI: 10.1080/08916152.2022.2145528
Unal Akdag, Melike Yukselturk, Hakan Palancioglu, S. Çalışkan
{"title":"Heat transfer enhancement in a square channel with a set of triangular prisms: an experimental study","authors":"Unal Akdag, Melike Yukselturk, Hakan Palancioglu, S. Çalışkan","doi":"10.1080/08916152.2022.2145528","DOIUrl":"https://doi.org/10.1080/08916152.2022.2145528","url":null,"abstract":"","PeriodicalId":12091,"journal":{"name":"Experimental Heat Transfer","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2022-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45242953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-11-11DOI: 10.1080/08916152.2022.2142703
K. Yogi, S. Krishnan, S. Prabhu
{"title":"Effect of metal foam thickness on the conduction and convection heat transfer for a flat plate with metal foam impinged by multiple jets","authors":"K. Yogi, S. Krishnan, S. Prabhu","doi":"10.1080/08916152.2022.2142703","DOIUrl":"https://doi.org/10.1080/08916152.2022.2142703","url":null,"abstract":"","PeriodicalId":12091,"journal":{"name":"Experimental Heat Transfer","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2022-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43787386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-11-09DOI: 10.1080/08916152.2022.2139024
Karmveer, N. Kumar Gupta, Tabish Alam, Himanshu Singh
{"title":"An Experimental Study of Thermohydraulic Performance of Solar Air Heater Having Multiple Open Trapezoidal Rib Roughnesses","authors":"Karmveer, N. Kumar Gupta, Tabish Alam, Himanshu Singh","doi":"10.1080/08916152.2022.2139024","DOIUrl":"https://doi.org/10.1080/08916152.2022.2139024","url":null,"abstract":"","PeriodicalId":12091,"journal":{"name":"Experimental Heat Transfer","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2022-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46684190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-11-06DOI: 10.1080/08916152.2022.2142701
Reda A. khalaf-allah, E. Eid, Abd-El Hamid A. Ellithy, A. Easa
{"title":"Experimental Investigation of The Influence of Modifying the Inner Tube Outer Surface on Free Convection in A Concentrated Double Pipe","authors":"Reda A. khalaf-allah, E. Eid, Abd-El Hamid A. Ellithy, A. Easa","doi":"10.1080/08916152.2022.2142701","DOIUrl":"https://doi.org/10.1080/08916152.2022.2142701","url":null,"abstract":"","PeriodicalId":12091,"journal":{"name":"Experimental Heat Transfer","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2022-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44346215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-11-03DOI: 10.1080/08916152.2022.2142702
Siva K. Bathina, S. Siddapureddy
{"title":"Experimental investigation of flame height and air entrainment of n-heptane double open pool fires","authors":"Siva K. Bathina, S. Siddapureddy","doi":"10.1080/08916152.2022.2142702","DOIUrl":"https://doi.org/10.1080/08916152.2022.2142702","url":null,"abstract":"","PeriodicalId":12091,"journal":{"name":"Experimental Heat Transfer","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2022-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49359660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-10-20DOI: 10.1080/08916152.2022.2136284
T. O. Scott, D. Ewim, A. Eloka‐Eboka
{"title":"Experimental investigation of natural convection Al2O3-MWCNT/water hybrid nanofluids inside a square cavity","authors":"T. O. Scott, D. Ewim, A. Eloka‐Eboka","doi":"10.1080/08916152.2022.2136284","DOIUrl":"https://doi.org/10.1080/08916152.2022.2136284","url":null,"abstract":"","PeriodicalId":12091,"journal":{"name":"Experimental Heat Transfer","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2022-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43458210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-26eCollection Date: 2022-09-01DOI: 10.36519/idcm.2022.139
İsmail Çelik, Ezgi Gülten, Arzu Onay-Beşikci, Güle Çınar, İrem Akdemir-Kalkan, Gülgün Kılcıgil, K Osman Memikoğlu, M Serhat Birengel, Alpay Azap
Objective: Highly contagious character of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the lack of specific drugs have led many scientists worldwide to re-evaluate the molecules currently in use for other diseases/viruses. Thus, high-throughput screening with docking studies has the rationale to identify potential therapeutics from existing drug molecules. Conflicting results of the studies, including SARS-CoV-2 and human immunodeficiency virus (HIV) coinfected population, suggested a possible preventive effect of antiretroviral regimens they have been receiving.
Materials and methods: Interactions between the widely used antiretroviral molecules, in particular; abacavir, cobicistat, dolutegravir, elvitegravir, emtricitabine, lamivudine, raltegravir, and tenofovir, and the main proteins on SARS-CoV-2 that may be targeted for SARS-CoV-2 infection were analyzed using molecular docking studies.
Results: Analysis of the compounds strikingly revealed that not the antiretroviral drugs but cobicistat and ritonavir, the inhibitors of cytochrome P450, had strong interactions with the main protease active site and RNA polymerase on SARS-CoV-2, as well as the active site of angiotensin-converting-enzyme 2, the protein that enables the entry of the virus into human cells.
Conclusion: Our results suggest cobicistat and ritonavir may be used to prevent SARS-CoV-2 infection.
{"title":"SARS-CoV-2 Infection may be Prevented with Cytochrome Inhibitors: Cobicistat and Ritonavir.","authors":"İsmail Çelik, Ezgi Gülten, Arzu Onay-Beşikci, Güle Çınar, İrem Akdemir-Kalkan, Gülgün Kılcıgil, K Osman Memikoğlu, M Serhat Birengel, Alpay Azap","doi":"10.36519/idcm.2022.139","DOIUrl":"10.36519/idcm.2022.139","url":null,"abstract":"<p><strong>Objective: </strong>Highly contagious character of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the lack of specific drugs have led many scientists worldwide to re-evaluate the molecules currently in use for other diseases/viruses. Thus, high-throughput screening with docking studies has the rationale to identify potential therapeutics from existing drug molecules. Conflicting results of the studies, including SARS-CoV-2 and human immunodeficiency virus (HIV) coinfected population, suggested a possible preventive effect of antiretroviral regimens they have been receiving.</p><p><strong>Materials and methods: </strong>Interactions between the widely used antiretroviral molecules, in particular; abacavir, cobicistat, dolutegravir, elvitegravir, emtricitabine, lamivudine, raltegravir, and tenofovir, and the main proteins on SARS-CoV-2 that may be targeted for SARS-CoV-2 infection were analyzed using molecular docking studies.</p><p><strong>Results: </strong>Analysis of the compounds strikingly revealed that not the antiretroviral drugs but cobicistat and ritonavir, the inhibitors of cytochrome P450, had strong interactions with the main protease active site and RNA polymerase on SARS-CoV-2, as well as the active site of angiotensin-converting-enzyme 2, the protein that enables the entry of the virus into human cells.</p><p><strong>Conclusion: </strong>Our results suggest cobicistat and ritonavir may be used to prevent SARS-CoV-2 infection.</p>","PeriodicalId":12091,"journal":{"name":"Experimental Heat Transfer","volume":"18 1","pages":"185-191"},"PeriodicalIF":0.0,"publicationDate":"2022-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10986712/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81496940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-22DOI: 10.1080/08916152.2022.2126031
A. Singh, Kuldeep Singh, Dushyant Singh, N. Sahoo
{"title":"Experimental and numerical analysis of film cooling performance of a corrugated surface","authors":"A. Singh, Kuldeep Singh, Dushyant Singh, N. Sahoo","doi":"10.1080/08916152.2022.2126031","DOIUrl":"https://doi.org/10.1080/08916152.2022.2126031","url":null,"abstract":"","PeriodicalId":12091,"journal":{"name":"Experimental Heat Transfer","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2022-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44967149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-19DOI: 10.1080/08916152.2022.2126029
Gorasiya A.V., Vedula R.P
{"title":"Heat transfer characteristics of jet impingement onto the concave surface of a cone","authors":"Gorasiya A.V., Vedula R.P","doi":"10.1080/08916152.2022.2126029","DOIUrl":"https://doi.org/10.1080/08916152.2022.2126029","url":null,"abstract":"","PeriodicalId":12091,"journal":{"name":"Experimental Heat Transfer","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2022-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41863022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-07DOI: 10.1080/08916152.2022.2121875
W. Fan, Feng-quan Zhong
{"title":"Experimental study on flow and heat transfer of Al-kerosene nanofuels for regenerative cooling application","authors":"W. Fan, Feng-quan Zhong","doi":"10.1080/08916152.2022.2121875","DOIUrl":"https://doi.org/10.1080/08916152.2022.2121875","url":null,"abstract":"","PeriodicalId":12091,"journal":{"name":"Experimental Heat Transfer","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2022-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48282220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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