Pub Date : 2017-12-01Epub Date: 2017-10-22DOI: 10.1136/ebmed-2017-110828
Liangzhi Xu, Xiaoyong Qiao
{"title":"Acupuncture is not as effective as infertility treatment in women with PCOS.","authors":"Liangzhi Xu, Xiaoyong Qiao","doi":"10.1136/ebmed-2017-110828","DOIUrl":"10.1136/ebmed-2017-110828","url":null,"abstract":"","PeriodicalId":12182,"journal":{"name":"Evidence-Based Medicine","volume":" ","pages":"229-230"},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/7a/be/ebmed-2017-110828.PMC5750408.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35535242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-12-01Epub Date: 2017-11-10DOI: 10.1136/ebmed-2017-110759
Roderick C N van den Bergh, Marie-Anne van Stam
Context Many patients with prostate cancer are diagnosed with low-risk disease only, for whom the benefit of surgery or radiation on life expectancy may be very limited, while still bringing the risk of side effects. 2 Therefore, patients with low-risk prostate cancer are currently offered the option of active surveillance. This strategy delays therapy with curative intent until progression occurs, or it may completely avoid radical treatment. As a result, in the treatment decision-making process of patients newly diagnosed with prostate cancer, up-to-date and preferably personalised information about the possible positive and negative effects of the treatment options is vital.
{"title":"In patients with localised prostate cancer, active surveillance is associated with better sexual function, urinary symptoms and bowel symptoms.","authors":"Roderick C N van den Bergh, Marie-Anne van Stam","doi":"10.1136/ebmed-2017-110759","DOIUrl":"https://doi.org/10.1136/ebmed-2017-110759","url":null,"abstract":"Context Many patients with prostate cancer are diagnosed with low-risk disease only, for whom the benefit of surgery or radiation on life expectancy may be very limited, while still bringing the risk of side effects. 2 Therefore, patients with low-risk prostate cancer are currently offered the option of active surveillance. This strategy delays therapy with curative intent until progression occurs, or it may completely avoid radical treatment. As a result, in the treatment decision-making process of patients newly diagnosed with prostate cancer, up-to-date and preferably personalised information about the possible positive and negative effects of the treatment options is vital.","PeriodicalId":12182,"journal":{"name":"Evidence-Based Medicine","volume":" ","pages":"217-218"},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/ebmed-2017-110759","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35543510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-12-01Epub Date: 2017-10-25DOI: 10.1136/ebmed-2017-110725
Nick Daneman
Commentary on: Freedberg DE, Salmasian H, Cohen B, et al . Receipt of antibiotics in hospitalized patients and risk for Clostridium difficile infection in subsequent patients who occupy the same bed . JAMA Intern Med 2016;176:1801–8. Patients are at heightened risk of Clostridium difficile- associated disease when they are exposed to both the organism and to antibiotic treatments, which deplete their normal, diverse, protective gastrointestinal flora. Both of these factors are prevalent in healthcare facilities, and thus C. difficile is the most common and most burdensome hospital-acquired pathogen.1 The hazards of antibiotic use may extend beyond the individual patient. As ward-level antibiotic use increases, so too does an individual patient’s risk of C. difficile infection, even when he or she has not directly received antibiotics.2 In this study, Freedberg et al aim to provide perhaps the most direct evidence of the indirect hazards of antibiotic use on the risk of C. difficile —by testing whether antibiotic receipt by a …
{"title":"Prescribing antibiotics to hospitalised patients increases the risk of <i>Clostridium difficile</i> infection for the next bed occupant.","authors":"Nick Daneman","doi":"10.1136/ebmed-2017-110725","DOIUrl":"https://doi.org/10.1136/ebmed-2017-110725","url":null,"abstract":"Commentary on: Freedberg DE, Salmasian H, Cohen B, et al . Receipt of antibiotics in hospitalized patients and risk for Clostridium difficile infection in subsequent patients who occupy the same bed . JAMA Intern Med 2016;176:1801–8.\u0000\u0000Patients are at heightened risk of Clostridium difficile- associated disease when they are exposed to both the organism and to antibiotic treatments, which deplete their normal, diverse, protective gastrointestinal flora. Both of these factors are prevalent in healthcare facilities, and thus C. difficile is the most common and most burdensome hospital-acquired pathogen.1 The hazards of antibiotic use may extend beyond the individual patient. As ward-level antibiotic use increases, so too does an individual patient’s risk of C. difficile infection, even when he or she has not directly received antibiotics.2 In this study, Freedberg et al aim to provide perhaps the most direct evidence of the indirect hazards of antibiotic use on the risk of C. difficile —by testing whether antibiotic receipt by a …","PeriodicalId":12182,"journal":{"name":"Evidence-Based Medicine","volume":" ","pages":"212"},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/ebmed-2017-110725","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35543619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-12-01Epub Date: 2017-11-23DOI: 10.1136/ebmed-2017-110848
Carlos Collet, Patrick W Serruys
{"title":"Early invasive strategy should be performed within 72 hours in high-risk patients with non-ST-elevation myocardial infarction.","authors":"Carlos Collet, Patrick W Serruys","doi":"10.1136/ebmed-2017-110848","DOIUrl":"10.1136/ebmed-2017-110848","url":null,"abstract":"","PeriodicalId":12182,"journal":{"name":"Evidence-Based Medicine","volume":" ","pages":"227"},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35634300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-12-01Epub Date: 2017-11-02DOI: 10.1136/ebmed-2017-110745
Muhammad Zaman Khan Assir, Fraz Ahmad
{"title":"Prophylactic platelet transfusion does not reduce risk of clinical bleeding in adults with dengue and thrombocytopaenia.","authors":"Muhammad Zaman Khan Assir, Fraz Ahmad","doi":"10.1136/ebmed-2017-110745","DOIUrl":"10.1136/ebmed-2017-110745","url":null,"abstract":"","PeriodicalId":12182,"journal":{"name":"Evidence-Based Medicine","volume":" ","pages":"225"},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35219005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-12-01Epub Date: 2017-11-10DOI: 10.1136/ebmed-2017-110796
Loren G Miller
{"title":"Cephalexin plus trimethoprim-sulfamethoxazole was not superior to cephalexin alone for the treatment of outpatient non-purulent cellulitis.","authors":"Loren G Miller","doi":"10.1136/ebmed-2017-110796","DOIUrl":"10.1136/ebmed-2017-110796","url":null,"abstract":"","PeriodicalId":12182,"journal":{"name":"Evidence-Based Medicine","volume":" ","pages":"213"},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35543507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-12-01Epub Date: 2017-09-18DOI: 10.1136/ebmed-2017-110812
Martin J Holzmann
Commentary on: Pickering JW, Than P, Cullen L, et al . Rapid rule-out of acute myocardial infarction with a single high-sensitivity cardiac troponin T measurement below the limit of detection. Ann Intern Med 2017;166:715–24. Historically, it has been regarded that at least two measurements of cardiac biomarkers, with 6 hours in between, are needed in order to rule out acute myocardial infarction (AMI). With the introduction of high-sensitivity cardiac troponin (hs-cTn) assays, the time it takes to detect signs of myocyte necrosis has shortened considerably.1 In an observational cohort study published in 2014, it was found that the risk of AMI within 30 days was 0.2% if the first high-sensitivity cardiac troponin T (hs-cTnT) measurement was <5 ng/L.2 The authors suggested that it was safe to discharge all patients with chest pain with a non-ischaemic ECG, if the first …
{"title":"Acute myocardial infarction can be ruled out with a single high-sensitivity cardiac troponin T level.","authors":"Martin J Holzmann","doi":"10.1136/ebmed-2017-110812","DOIUrl":"https://doi.org/10.1136/ebmed-2017-110812","url":null,"abstract":"Commentary on: Pickering JW, Than P, Cullen L, et al . Rapid rule-out of acute myocardial infarction with a single high-sensitivity cardiac troponin T measurement below the limit of detection. Ann Intern Med 2017;166:715–24.\u0000\u0000Historically, it has been regarded that at least two measurements of cardiac biomarkers, with 6 hours in between, are needed in order to rule out acute myocardial infarction (AMI). With the introduction of high-sensitivity cardiac troponin (hs-cTn) assays, the time it takes to detect signs of myocyte necrosis has shortened considerably.1 In an observational cohort study published in 2014, it was found that the risk of AMI within 30 days was 0.2% if the first high-sensitivity cardiac troponin T (hs-cTnT) measurement was <5 ng/L.2 The authors suggested that it was safe to discharge all patients with chest pain with a non-ischaemic ECG, if the first …","PeriodicalId":12182,"journal":{"name":"Evidence-Based Medicine","volume":" ","pages":"226"},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/ebmed-2017-110812","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35421719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-12-01Epub Date: 2017-11-18DOI: 10.1136/ebmed-2017-110835
Yüksel Peker, Patrick J Strollo
{"title":"A meta-analysis of positive airway pressure treatment for cardiovascular prevention: why mix apples and pears?","authors":"Yüksel Peker, Patrick J Strollo","doi":"10.1136/ebmed-2017-110835","DOIUrl":"10.1136/ebmed-2017-110835","url":null,"abstract":"","PeriodicalId":12182,"journal":{"name":"Evidence-Based Medicine","volume":" ","pages":"218-219"},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/49/13/ebmed-2017-110835.PMC5750407.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35259175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-10-01Epub Date: 2017-08-16DOI: 10.1136/ebmed-2017-110787
Sabine Rohrmann, Jakob Linseisen
Commentary on: Etemadi, A, Sinha R, Ward MH, et al. Mortality from different causes associated with meat, heme iron, nitrates, and nitrites in the NIH-AARP Diet and Health Study: population based cohort study. BMJ 2017;357:j1957. The International Agency for Research on Cancer categorised processed meat as carcinogenic to humans in 2015.1 High red and processed meat consumption is positively associated with risk of cardiovascular disease and type 2 diabetes as well as overall mortality.2 Usually the intake of processed red meat is found to be more strongly associated with disease outcomes than unprocessed red meat, which is thought to be due to preservation methods such as salting, curing and smoking, increasing the concentration of potentially hazardous substances in meat.3 In the US National Institutes of Health-American Association of Retired Persons (NIH-AARP) …
{"title":"Haem iron and nitrate/nitrite account for much of the mortality increase associated with red meat consumption.","authors":"Sabine Rohrmann, Jakob Linseisen","doi":"10.1136/ebmed-2017-110787","DOIUrl":"https://doi.org/10.1136/ebmed-2017-110787","url":null,"abstract":"Commentary on: Etemadi, A, Sinha R, Ward MH, et al. Mortality from different causes associated with meat, heme iron, nitrates, and nitrites in the NIH-AARP Diet and Health Study: population based cohort study. BMJ 2017;357:j1957.\u0000\u0000The International Agency for Research on Cancer categorised processed meat as carcinogenic to humans in 2015.1 High red and processed meat consumption is positively associated with risk of cardiovascular disease and type 2 diabetes as well as overall mortality.2 Usually the intake of processed red meat is found to be more strongly associated with disease outcomes than unprocessed red meat, which is thought to be due to preservation methods such as salting, curing and smoking, increasing the concentration of potentially hazardous substances in meat.3 \u0000\u0000In the US National Institutes of Health-American Association of Retired Persons (NIH-AARP) …","PeriodicalId":12182,"journal":{"name":"Evidence-Based Medicine","volume":"22 5","pages":"179"},"PeriodicalIF":0.0,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/ebmed-2017-110787","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35328649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-10-01Epub Date: 2017-08-29DOI: 10.1136/ebmed-2017-110802
Andrea Messori, Sabrina Trippoli, Claudio Marinai
We recently surveyed the literature on the effectiveness of three classes of implantable devices: (1) stents for carotid artery stenosis, (2) endovascular clips or coils for unruptured intracranial aneurysms and (3) prostheses for endovascular treatment of ruptured abdominal aneurysms. These three device-based interventions were selected because, at our Regional Health System, we were requested to undertake a series of competitive tenders for the procurement of these devices. To synthetise the clinical literature on these topics, we adopted the empirical criterion of identifying—by expert consensus—the ‘best’ single meta-analysis …
{"title":"Effectiveness of interventions based on implantable devices: meta-analyses or systematic reviews that fail to indicate which device brands were used.","authors":"Andrea Messori, Sabrina Trippoli, Claudio Marinai","doi":"10.1136/ebmed-2017-110802","DOIUrl":"https://doi.org/10.1136/ebmed-2017-110802","url":null,"abstract":"We recently surveyed the literature on the effectiveness of three classes of implantable devices: (1) stents for carotid artery stenosis, (2) endovascular clips or coils for unruptured intracranial aneurysms and (3) prostheses for endovascular treatment of ruptured abdominal aneurysms. These three device-based interventions were selected because, at our Regional Health System, we were requested to undertake a series of competitive tenders for the procurement of these devices.\u0000\u0000To synthetise the clinical literature on these topics, we adopted the empirical criterion of identifying—by expert consensus—the ‘best’ single meta-analysis …","PeriodicalId":12182,"journal":{"name":"Evidence-Based Medicine","volume":"22 5","pages":"195"},"PeriodicalIF":0.0,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/ebmed-2017-110802","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35455834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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