首页 > 最新文献

Frontiers in Biology最新文献

英文 中文
Biosynthesis of polyhydroxyalkanoates from styrene by Enterobacter spp. isolated from polluted environment 污染环境中分离的肠杆菌以苯乙烯为原料合成聚羟基烷酸酯的研究
Frontiers in Biology
Pub Date : 2017-06-19 DOI: 10.1007/s11515-017-1446-2
A. Arshad, Bisma Ashraf, I. Ali, N. Jamil
{"title":"Biosynthesis of polyhydroxyalkanoates from styrene by Enterobacter spp. isolated from polluted environment","authors":"A. Arshad, Bisma Ashraf, I. Ali, N. Jamil","doi":"10.1007/s11515-017-1446-2","DOIUrl":"https://doi.org/10.1007/s11515-017-1446-2","url":null,"abstract":"","PeriodicalId":12454,"journal":{"name":"Frontiers in Biology","volume":"12 1","pages":"210-218"},"PeriodicalIF":0.0,"publicationDate":"2017-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s11515-017-1446-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43778343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
How to manage rheumatoid arthritis according to classic biomarkers and polymorphisms? 如何根据经典的生物标志物和多态性来管理类风湿性关节炎？
Frontiers in Biology
Pub Date : 2017-06-19 DOI: 10.1007/s11515-017-1452-4
K. Mowla, M. Saki, M. Jalali, Z. Zayeri
{"title":"How to manage rheumatoid arthritis according to classic biomarkers and polymorphisms?","authors":"K. Mowla, M. Saki, M. Jalali, Z. Zayeri","doi":"10.1007/s11515-017-1452-4","DOIUrl":"https://doi.org/10.1007/s11515-017-1452-4","url":null,"abstract":"","PeriodicalId":12454,"journal":{"name":"Frontiers in Biology","volume":"12 1","pages":"183-191"},"PeriodicalIF":0.0,"publicationDate":"2017-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s11515-017-1452-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43304491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
Effect of psychological preparation on anxiety level before colonoscopy in outpatients referred to Golestan Hospital in Ahvaz 心理准备对阿瓦士戈列斯坦医院门诊患者结肠镜检查前焦虑水平的影响
Frontiers in Biology
Pub Date : 2017-06-19 DOI: 10.1007/s11515-017-1451-5
H. Boustani, S. Pakseresht, M. Haghdoust, Saeid Qanbari, Hadis Mehregan-Nasab
{"title":"Effect of psychological preparation on anxiety level before colonoscopy in outpatients referred to Golestan Hospital in Ahvaz","authors":"H. Boustani, S. Pakseresht, M. Haghdoust, Saeid Qanbari, Hadis Mehregan-Nasab","doi":"10.1007/s11515-017-1451-5","DOIUrl":"https://doi.org/10.1007/s11515-017-1451-5","url":null,"abstract":"","PeriodicalId":12454,"journal":{"name":"Frontiers in Biology","volume":"12 1","pages":"235-239"},"PeriodicalIF":0.0,"publicationDate":"2017-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s11515-017-1451-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42659914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Succinate dehydrogenase in Parkinson’s disease 帕金森病的琥珀酸脱氢酶
Frontiers in Biology
Pub Date : 2017-06-19 DOI: 10.1007/s11515-017-1450-6
Mohammad Jodeiri Farshbaf
{"title":"Succinate dehydrogenase in Parkinson’s disease","authors":"Mohammad Jodeiri Farshbaf","doi":"10.1007/s11515-017-1450-6","DOIUrl":"https://doi.org/10.1007/s11515-017-1450-6","url":null,"abstract":"","PeriodicalId":12454,"journal":{"name":"Frontiers in Biology","volume":"12 1","pages":"175-182"},"PeriodicalIF":0.0,"publicationDate":"2017-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s11515-017-1450-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46602056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Analysis of curcumin interaction with human serum albumin using spectroscopic studies with molecular simulation 姜黄素与人血清白蛋白相互作用的分子模拟光谱分析
Frontiers in Biology
Pub Date : 2017-06-19 DOI: 10.1007/s11515-017-1449-z
T. Kar, P. Basak, S. Sen, R. Ghosh, M. Bhattacharyya
{"title":"Analysis of curcumin interaction with human serum albumin using spectroscopic studies with molecular simulation","authors":"T. Kar, P. Basak, S. Sen, R. Ghosh, M. Bhattacharyya","doi":"10.1007/s11515-017-1449-z","DOIUrl":"https://doi.org/10.1007/s11515-017-1449-z","url":null,"abstract":"","PeriodicalId":12454,"journal":{"name":"Frontiers in Biology","volume":"12 1","pages":"199-209"},"PeriodicalIF":0.0,"publicationDate":"2017-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s11515-017-1449-z","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43246346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 27
Inhibition and attenuation of pathogenicity of Porphyromonas gingivalis by leupeptin: A review 亮肽对牙龈卟啉单胞菌致病性的抑制和减弱作用
Frontiers in Biology
Pub Date : 2017-06-19 DOI: 10.1007/s11515-017-1442-6
H. Jain
{"title":"Inhibition and attenuation of pathogenicity of Porphyromonas gingivalis by leupeptin: A review","authors":"H. Jain","doi":"10.1007/s11515-017-1442-6","DOIUrl":"https://doi.org/10.1007/s11515-017-1442-6","url":null,"abstract":"","PeriodicalId":12454,"journal":{"name":"Frontiers in Biology","volume":"12 1","pages":"192-198"},"PeriodicalIF":0.0,"publicationDate":"2017-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s11515-017-1442-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48001661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
In vitro and in silico studies on fibrinolytic activity of nattokinase: A clot buster from Bacillus sp. 胞芽孢杆菌抗凝血剂纳豆激酶纤溶活性的体外和计算机研究。
Frontiers in Biology
Pub Date : 2017-06-07 DOI: 10.1007/s11515-017-1453-3
V. Mohanasrinivasan, A. Mohanapriya, S. Potdar, S. Chatterji, S. Konne, S. Kumari, S. M. Keziah, C. Subathra Devi
{"title":"In vitro and in silico studies on fibrinolytic activity of nattokinase: A clot buster from Bacillus sp.","authors":"V. Mohanasrinivasan, A. Mohanapriya, S. Potdar, S. Chatterji, S. Konne, S. Kumari, S. M. Keziah, C. Subathra Devi","doi":"10.1007/s11515-017-1453-3","DOIUrl":"https://doi.org/10.1007/s11515-017-1453-3","url":null,"abstract":"","PeriodicalId":12454,"journal":{"name":"Frontiers in Biology","volume":"12 1","pages":"219-225"},"PeriodicalIF":0.0,"publicationDate":"2017-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s11515-017-1453-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45503372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
PTEN at the interface of immune tolerance and tumor suppression. PTEN在免疫耐受和肿瘤抑制的界面。
Frontiers in Biology
Pub Date : 2017-06-01 Epub Date: 2017-03-04 DOI: 10.1007/s11515-017-1443-5
Andrew Brandmaier, Sheng-Qi Hou, Sandra Demaria, Silvia C Formenti, Wen H Shen

Background: PTEN is well known to function as a tumor suppressor that antagonizes oncogenic signaling and maintains genomic stability. The PTEN gene is frequently deleted or mutated in human cancers and the wide cancer spectrum associated with PTEN deficiency has been recapitulated in a variety of mouse models of Pten deletion or mutation. Pten mutations are highly penetrant in causing various types of spontaneous tumors that often exhibit resistance to anticancer therapies including immunotherapy. Recent studies demonstrate that PTEN also regulates immune functionality.

Objective: To understand the multifaceted functions of PTEN as both a tumor suppressor and an immune regulator.

Methods: This review will summarize the emerging knowledge of PTEN function in cancer immunoediting. In addition, the mechanisms underlying functional integration of various PTEN pathways in regulating cancer evolution and tumor immunity will be highlighted.

Results: Recent preclinical and clinical studies revealed the essential role of PTEN in maintaining immune homeostasis, which significantly expands the repertoire of PTEN functions. Mechanistically, aberrant PTEN signaling alters the interplay between the immune system and tumors, leading to immunosuppression and tumor escape.

Conclusion: Rational design of personalized anti-cancer treatment requires mechanistic understanding of diverse PTEN signaling pathways in modulation of the crosstalk between tumor and immune cells.

背景:PTEN被认为是一种肿瘤抑制因子，可拮抗致癌信号传导并维持基因组稳定性。PTEN基因在人类癌症中经常缺失或突变，与PTEN缺失相关的广泛癌症谱已经在各种PTEN缺失或突变的小鼠模型中得到了概括。Pten突变在引起各种类型的自发肿瘤中具有高度渗透性，这些自发肿瘤通常对包括免疫治疗在内的抗癌治疗具有耐药性。最近的研究表明，PTEN也调节免疫功能。目的:了解PTEN作为肿瘤抑制因子和免疫调节因子的多重功能。方法:本文将对PTEN在肿瘤免疫编辑中的作用进行综述。此外，各种PTEN通路在调节癌症进化和肿瘤免疫中的功能整合机制将被强调。结果:最近的临床前和临床研究揭示了PTEN在维持免疫稳态中的重要作用，这大大扩展了PTEN的功能范围。从机制上讲，异常的PTEN信号改变了免疫系统和肿瘤之间的相互作用，导致免疫抑制和肿瘤逃逸。结论:合理设计个体化抗癌治疗方案，需要了解多种PTEN信号通路调控肿瘤与免疫细胞间串扰的机制。
{"title":"PTEN at the interface of immune tolerance and tumor suppression.","authors":"Andrew Brandmaier,&nbsp;Sheng-Qi Hou,&nbsp;Sandra Demaria,&nbsp;Silvia C Formenti,&nbsp;Wen H Shen","doi":"10.1007/s11515-017-1443-5","DOIUrl":"https://doi.org/10.1007/s11515-017-1443-5","url":null,"abstract":"<p><strong>Background: </strong>PTEN is well known to function as a tumor suppressor that antagonizes oncogenic signaling and maintains genomic stability. The <i>PTEN</i> gene is frequently deleted or mutated in human cancers and the wide cancer spectrum associated with PTEN deficiency has been recapitulated in a variety of mouse models of <i>Pten</i> deletion or mutation. <i>Pten</i> mutations are highly penetrant in causing various types of spontaneous tumors that often exhibit resistance to anticancer therapies including immunotherapy. Recent studies demonstrate that PTEN also regulates immune functionality.</p><p><strong>Objective: </strong>To understand the multifaceted functions of PTEN as both a tumor suppressor and an immune regulator.</p><p><strong>Methods: </strong>This review will summarize the emerging knowledge of PTEN function in cancer immunoediting. In addition, the mechanisms underlying functional integration of various PTEN pathways in regulating cancer evolution and tumor immunity will be highlighted.</p><p><strong>Results: </strong>Recent preclinical and clinical studies revealed the essential role of PTEN in maintaining immune homeostasis, which significantly expands the repertoire of PTEN functions. Mechanistically, aberrant PTEN signaling alters the interplay between the immune system and tumors, leading to immunosuppression and tumor escape.</p><p><strong>Conclusion: </strong>Rational design of personalized anti-cancer treatment requires mechanistic understanding of diverse PTEN signaling pathways in modulation of the crosstalk between tumor and immune cells.</p>","PeriodicalId":12454,"journal":{"name":"Frontiers in Biology","volume":"12 3","pages":"163-174"},"PeriodicalIF":0.0,"publicationDate":"2017-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s11515-017-1443-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35901839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 17
Cationic antimicrobial peptide: LL-37 and its role in periodontitis 阳离子抗菌肽:LL-37及其在牙周炎中的作用
Frontiers in Biology
Pub Date : 2017-04-14 DOI: 10.1007/s11515-017-1432-8
H. Jain
{"title":"Cationic antimicrobial peptide: LL-37 and its role in periodontitis","authors":"H. Jain","doi":"10.1007/s11515-017-1432-8","DOIUrl":"https://doi.org/10.1007/s11515-017-1432-8","url":null,"abstract":"","PeriodicalId":12454,"journal":{"name":"Frontiers in Biology","volume":"12 1","pages":"116-123"},"PeriodicalIF":0.0,"publicationDate":"2017-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s11515-017-1432-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45183527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Tcf1 at the crossroads of CD4+ and CD8+ T cell identity Tcf1在CD4+和CD8+T细胞身份的十字路口
Frontiers in Biology
Pub Date : 2017-04-14 DOI: 10.1007/s11515-017-1445-3
Jodi A. Gullicksrud, Q. Shan, Hai-hui Xue
{"title":"Tcf1 at the crossroads of CD4+ and CD8+ T cell identity","authors":"Jodi A. Gullicksrud, Q. Shan, Hai-hui Xue","doi":"10.1007/s11515-017-1445-3","DOIUrl":"https://doi.org/10.1007/s11515-017-1445-3","url":null,"abstract":"","PeriodicalId":12454,"journal":{"name":"Frontiers in Biology","volume":"12 1","pages":"83-93"},"PeriodicalIF":0.0,"publicationDate":"2017-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s11515-017-1445-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47750726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
首页 上一页 下一页 尾页
类型
全部 化学•材料 生命科学 医学 物理 工程技术 环境•农林 材料科学 地球科学 法学 管理学 化学 环境科学与生态学 计算机科学 教育学 经济学 农林科学 人文科学 生物学 数学 物理与天体物理 心理学 综合性期刊 其他 工业工程 理学 历史学 农学 文学 信息工程
数据库
全部 ACS Publications Elsevier ieeexplore Springer The Royal Society of Chemistry Wiley
期刊
Frontiers in Biology
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
﹀
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们：info@booksci.cn
Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1