首页 > 最新文献

Gaceta Médica de Caracas最新文献

英文 中文
Anatomical studies at Universidad Central de Venezuela during 1763-1963 1763-1963年委内瑞拉中央大学解剖研究
Pub Date : 2023-09-16 DOI: 10.47307/gmc.2023.131.3.26
Rafael Romero-Reverón
In Venezuela, Medical studies began in 1763 at Real and Pontifical University of Caracas, conducted by Lorenzo Campins y Ballester. Afterward, José María Vargas, as the first rector of the successive University of Caracas, 1827 reformed the studies of Medicine, Surgery, and Anatomy. He gave lectures and performed anatomical dissections for 25 years. Vargas wrote Curso de Lecciones y demostraciones Anatómicas in 1838. Even under precarious conditions for medical education, a saga of anatomists managed to persist in anatomical studies in Venezuela. In the 20th century, a progressive development in anatomical studies began, led by Luis Razetti and extended by José Izquierdo. Subsequently, these improvements were promoted and developed in both medical schools of the Central University of Venezuela by Jesús Yerena, founder of the Anatomical Museum, and by Francisco Montbrun, founder of “José María Vargas” Medical School and its chair of human anatomy.
在委内瑞拉,医学研究始于1763年在加拉加斯的皇家和教皇大学,由洛伦佐·坎平斯·巴列斯特领导。之后,1827年,jos María Vargas作为加拉加斯大学的第一任校长,改革了医学、外科和解剖学的研究。他做了25年的讲座和解剖手术。巴尔加斯在1838年写了《民主论》Anatómicas。即使在不稳定的医学教育条件下,一群解剖学家在委内瑞拉设法坚持解剖研究。在20世纪,解剖学研究开始逐步发展,由Luis Razetti领导,由jos Izquierdo扩展。随后,解剖博物馆的创始人Jesús Yerena和joses María Vargas医学院的创始人兼人体解剖学主席Francisco Montbrun在委内瑞拉中央大学的两所医学院促进和发展了这些改进。
{"title":"Anatomical studies at Universidad Central de Venezuela during 1763-1963","authors":"Rafael Romero-Reverón","doi":"10.47307/gmc.2023.131.3.26","DOIUrl":"https://doi.org/10.47307/gmc.2023.131.3.26","url":null,"abstract":"In Venezuela, Medical studies began in 1763 at Real and Pontifical University of Caracas, conducted by Lorenzo Campins y Ballester. Afterward, José María Vargas, as the first rector of the successive University of Caracas, 1827 reformed the studies of Medicine, Surgery, and Anatomy. He gave lectures and performed anatomical dissections for 25 years. Vargas wrote Curso de Lecciones y demostraciones Anatómicas in 1838. Even under precarious conditions for medical education, a saga of anatomists managed to persist in anatomical studies in Venezuela. In the 20th century, a progressive development in anatomical studies began, led by Luis Razetti and extended by José Izquierdo. Subsequently, these improvements were promoted and developed in both medical schools of the Central University of Venezuela by Jesús Yerena, founder of the Anatomical Museum, and by Francisco Montbrun, founder of “José María Vargas” Medical School and its chair of human anatomy.","PeriodicalId":12577,"journal":{"name":"Gaceta Médica de Caracas","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135308657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Estandarización de la técnica PCR anidada para la detección de las translocaciones PML/RARα, RUNX1/RUNX1T1 y BCR/ABL en pacientes con leucemia mieloide aguda remitidos a la Unidad de Diagnóstico Molecular de la Fundación Jacinto Convit Jacinto Convit基金会分子诊断单位急性髓系白血病患者PML/RARα、RUNX1/RUNX1T1和BCR/ABL易位检测嵌套PCR技术的标准化
Pub Date : 2023-09-16 DOI: 10.47307/gmc.2023.131.3.9
Thais Rivodó
La detección de alteraciones genéticas en pacientes con leucemia mieloide aguda (LMA) permite un mejor pronóstico de la enfermedad y de la respuesta clínica de los pacientes. A través de la técnica de reacción en cadena de la polimerasa con transcripción reversa (RT-PCR, por sus siglas en inglés) anidada, es posible detectar hasta 1 célula mutada/10-6 células sanas, de las translocaciones cromosómicas más frecuentes en pacientes con LMA: t(15;17), t(8;21) y t(9;22). La sensibilidad y eficacia de esta técnica depende fundamentalmente del diseño de los cebadores utilizados en la reacción.
在急性髓系白血病(aml)患者中检测遗传改变可以更好地预后疾病和患者的临床反应。通过嵌套逆转录聚合酶链反应(RT-PCR)技术,可以检测到多达1个突变细胞/10-6个健康细胞,在aml患者中最常见的染色体易位:t(15;17), t(8;21)和t(9;22)。该技术的灵敏度和有效性主要取决于反应中使用的引物的设计。
{"title":"Estandarización de la técnica PCR anidada para la detección de las translocaciones PML/RARα, RUNX1/RUNX1T1 y BCR/ABL en pacientes con leucemia mieloide aguda remitidos a la Unidad de Diagnóstico Molecular de la Fundación Jacinto Convit","authors":"Thais Rivodó","doi":"10.47307/gmc.2023.131.3.9","DOIUrl":"https://doi.org/10.47307/gmc.2023.131.3.9","url":null,"abstract":"La detección de alteraciones genéticas en pacientes con leucemia mieloide aguda (LMA) permite un mejor pronóstico de la enfermedad y de la respuesta clínica de los pacientes. A través de la técnica de reacción en cadena de la polimerasa con transcripción reversa (RT-PCR, por sus siglas en inglés) anidada, es posible detectar hasta 1 célula mutada/10-6 células sanas, de las translocaciones cromosómicas más frecuentes en pacientes con LMA: t(15;17), t(8;21) y t(9;22). La sensibilidad y eficacia de esta técnica depende fundamentalmente del diseño de los cebadores utilizados en la reacción.","PeriodicalId":12577,"journal":{"name":"Gaceta Médica de Caracas","volume":"83 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135308668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Estudio piloto de la prevalencia del consumo de cigarrillos en adultos jóvenes en Maracaibo, Venezuela 委内瑞拉马拉开波年轻人吸烟流行率的初步研究
Pub Date : 2023-09-16 DOI: 10.47307/gmc.2023.131.3.11
Carlos Silva Paredes
Introducción: El tabaquismo se asocia con el desarrollo de enfermedades pulmonares crónicas, enfermedades cardiovasculares y distintos tipos de canceres. Los cigarrillos electrónicos son productos que se han considerados como una alternativa segura a los cigarrillos convencionales y, promocionados como menos dañinos. Estos dispositivos se han asociado a enfermedades pulmonares graves llamado EVALI. Objetivo: determinar la prevalencia del consumo de cigarrillos electrónicos y convencionales en la población de adultos jóvenes. Materiales y métodos: Se realizó un estudio piloto de tipo no experimental, transversal y descriptivo en 225 individuos seleccionados mediante un muestreo no probabilístico, de ambos sexos con edades comprendidas entre los 17 y 25 años de la ciudad de Maracaibo, Venezuela.
简介:吸烟与慢性肺病、心血管疾病和各种癌症的发展有关。电子烟被认为是传统香烟的安全替代品,并被宣传为危害较小。这些设备与被称为EVALI的严重肺部疾病有关。目的:确定电子烟和传统烟在年轻人中的流行程度。材料和方法:对委内瑞拉马拉开波市的225名年龄在17 - 25岁之间的男女进行了非实验性、横断面和描述性的初步研究。
{"title":"Estudio piloto de la prevalencia del consumo de cigarrillos en adultos jóvenes en Maracaibo, Venezuela","authors":"Carlos Silva Paredes","doi":"10.47307/gmc.2023.131.3.11","DOIUrl":"https://doi.org/10.47307/gmc.2023.131.3.11","url":null,"abstract":"Introducción: El tabaquismo se asocia con el desarrollo de enfermedades pulmonares crónicas, enfermedades cardiovasculares y distintos tipos de canceres. Los cigarrillos electrónicos son productos que se han considerados como una alternativa segura a los cigarrillos convencionales y, promocionados como menos dañinos. Estos dispositivos se han asociado a enfermedades pulmonares graves llamado EVALI. Objetivo: determinar la prevalencia del consumo de cigarrillos electrónicos y convencionales en la población de adultos jóvenes. Materiales y métodos: Se realizó un estudio piloto de tipo no experimental, transversal y descriptivo en 225 individuos seleccionados mediante un muestreo no probabilístico, de ambos sexos con edades comprendidas entre los 17 y 25 años de la ciudad de Maracaibo, Venezuela.","PeriodicalId":12577,"journal":{"name":"Gaceta Médica de Caracas","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135308672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endoscopic dacryocystorhinostomy as treatment for lacrimal pathway obstructions: Serial case reports 内镜下泪囊鼻腔造口术治疗泪道阻塞:系列病例报告
Pub Date : 2023-09-16 DOI: 10.47307/gmc.2023.131.3.23
Muhammad Fadjar Perkasa
Introduction: The lacrimal system is an important system for maintaining the normal condition of the ocular surface. Obstruction of the lacrimal duct can lead to inflammation and accumulation of debris and pathogens such as bacteria or fungi in the lacrimal sac and then cause dacryocystitis. This disease is often found in children or adults over 40 years of age, especially women with a peak incidence at the age of 60 to 70 years. Complaints usually include eye discomfort and redness accompanied by excessive tears. The diagnosis can be made based on physical examination, staining tests, and imaging photographs, such as dacryocystography, computed tomography (CT), and magnetic resonance imaging (MRI). Management of dacryocystitis is conservative, supportive, and surgical with an open or endonasal approach.
泪道系统是维持眼表正常状态的重要系统。泪道阻塞可导致泪囊内的炎症和碎屑及细菌、真菌等病原体的积聚,进而引起泪囊炎。本病常见于40岁以上的儿童或成人,尤其是妇女,60 ~ 70岁为发病高峰。主诉通常包括眼睛不适和红肿,并伴有过多的泪水。诊断可基于体格检查、染色试验和成像照片,如泪囊造影术、计算机断层扫描(CT)和磁共振成像(MRI)。泪囊炎的治疗是保守的,支持性的,手术和开放或鼻内入路。
{"title":"Endoscopic dacryocystorhinostomy as treatment for lacrimal pathway obstructions: Serial case reports","authors":"Muhammad Fadjar Perkasa","doi":"10.47307/gmc.2023.131.3.23","DOIUrl":"https://doi.org/10.47307/gmc.2023.131.3.23","url":null,"abstract":"Introduction: The lacrimal system is an important system for maintaining the normal condition of the ocular surface. Obstruction of the lacrimal duct can lead to inflammation and accumulation of debris and pathogens such as bacteria or fungi in the lacrimal sac and then cause dacryocystitis. This disease is often found in children or adults over 40 years of age, especially women with a peak incidence at the age of 60 to 70 years. Complaints usually include eye discomfort and redness accompanied by excessive tears. The diagnosis can be made based on physical examination, staining tests, and imaging photographs, such as dacryocystography, computed tomography (CT), and magnetic resonance imaging (MRI). Management of dacryocystitis is conservative, supportive, and surgical with an open or endonasal approach.","PeriodicalId":12577,"journal":{"name":"Gaceta Médica de Caracas","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135308658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Urogenital disease morbidity among the adult and child population of the Osh Region for the period from 2010 to 2019 2010 - 2019年奥什地区成人和儿童泌尿生殖系统疾病发病率
Pub Date : 2023-09-16 DOI: 10.47307/gmc.2023.131.3.17
Isabek Tazhidinovich Gulamov
It is presented the results of a study on the prevalence, structure, and trends in urogenital diseases in the adult population of the Osh Region of Kyrgyzstan for the period between 2010 and 2019. Official statistics on morbidity provided by the National Statistical Committee of the Kyrgyz Republic are used as materials for the study. Information on the main indices characterizing adult morbidity is selected and summarized, and dynamic statistical analysis of the data is performed. The data analysis demonstrates that the highest morbidity of urogenital diseases in the Osh Region was registered in 2017, and the lowest – in 2019.
本文介绍了2010年至2019年期间吉尔吉斯斯坦奥什地区成年人口中泌尿生殖系统疾病的患病率、结构和趋势的研究结果。本研究使用吉尔吉斯共和国国家统计委员会提供的关于发病率的官方统计数字作为材料。选取和总结表征成人发病率的主要指标信息,并对数据进行动态统计分析。数据分析表明,2017年奥什地区泌尿生殖系统疾病发病率最高,2019年最低。
{"title":"Urogenital disease morbidity among the adult and child population of the Osh Region for the period from 2010 to 2019","authors":"Isabek Tazhidinovich Gulamov","doi":"10.47307/gmc.2023.131.3.17","DOIUrl":"https://doi.org/10.47307/gmc.2023.131.3.17","url":null,"abstract":"It is presented the results of a study on the prevalence, structure, and trends in urogenital diseases in the adult population of the Osh Region of Kyrgyzstan for the period between 2010 and 2019. Official statistics on morbidity provided by the National Statistical Committee of the Kyrgyz Republic are used as materials for the study. Information on the main indices characterizing adult morbidity is selected and summarized, and dynamic statistical analysis of the data is performed. The data analysis demonstrates that the highest morbidity of urogenital diseases in the Osh Region was registered in 2017, and the lowest – in 2019.","PeriodicalId":12577,"journal":{"name":"Gaceta Médica de Caracas","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135308670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
COVID-19: Hematological and laboratory parameters in patients hospitalized during the second and third epidemic wave (2021-2022) at a private hospital in Caracas, Venezuela COVID-19:委内瑞拉加拉加斯一家私立医院第二波和第三波(2021-2022年)住院患者的血液学和实验室参数
Pub Date : 2023-09-16 DOI: 10.47307/gmc.2023.131.3.15
Aixa Müller
The first wave of COVID-19 in Venezuela began in March 2020 and had a maximum of cases in August 2020. New outbreaks occurred in 2021 and 2022, during which we studied 603 hospitalized cases at the Clinica El Avila de Caracas: 370 (61.35 %) male and 233 (38.14 %) female. The average age was 65 years (range: 18-99 years). The hematological and laboratory studies were similar to those reported in 2020other studies outside of Venezuela. One hundred two (102) patients were transferred to the Intensive Care Unit (ICU). 80 % of these patients had not been vaccinated or did not receive the full vaccination schedule against COVID-19. The overall mortality of the 603 patients was 11.27 %.
委内瑞拉的第一波COVID-19始于2020年3月,到2020年8月病例最多。2021年和2022年发生了新的疫情,在此期间,我们研究了加拉加斯诊所的603例住院病例:370例(61.35%)男性和233例(38.14%)女性。平均年龄65岁(18-99岁)。血液学和实验室研究与2020年委内瑞拉以外的其他研究报告相似。102例患者转至重症监护室(ICU)。这些患者中有80%没有接种疫苗或没有接受针对COVID-19的完整疫苗接种计划。603例患者的总死亡率为11.27%。
{"title":"COVID-19: Hematological and laboratory parameters in patients hospitalized during the second and third epidemic wave (2021-2022) at a private hospital in Caracas, Venezuela","authors":"Aixa Müller","doi":"10.47307/gmc.2023.131.3.15","DOIUrl":"https://doi.org/10.47307/gmc.2023.131.3.15","url":null,"abstract":"The first wave of COVID-19 in Venezuela began in March 2020 and had a maximum of cases in August 2020. New outbreaks occurred in 2021 and 2022, during which we studied 603 hospitalized cases at the Clinica El Avila de Caracas: 370 (61.35 %) male and 233 (38.14 %) female. The average age was 65 years (range: 18-99 years). The hematological and laboratory studies were similar to those reported in 2020other studies outside of Venezuela. One hundred two (102) patients were transferred to the Intensive Care Unit (ICU). 80 % of these patients had not been vaccinated or did not receive the full vaccination schedule against COVID-19. The overall mortality of the 603 patients was 11.27 %.","PeriodicalId":12577,"journal":{"name":"Gaceta Médica de Caracas","volume":"199 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135308651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Conceptos actuales del diagnóstico y tratamiento de la artritis psoriásica 银屑病关节炎的诊断和治疗的当前概念
Pub Date : 2023-09-16 DOI: 10.47307/gmc.2023.131.3.19
Juan Camilo Santacruz
La artritis psoriásica (APs) es una enfermedad autoinmune sistémica asociada a la psoriasis, conocida ahora dentro de un único espectro llamado enfermedad psoriásica, y otras comorbilidades como lo son enfermedad cardiovascular, síndrome metabólico, inflamación intestinal subclínica, trastornos del estado de ánimo, mayor riesgo de infecciones crónicas y fibromialgia. El compromiso articular en esta enfermedad es de presentación heterogénea, incluyendo tanto las articulaciones periféricas como axiales, acompañadas de otras manifestaciones clínicas como lo son la presencia de entesitis, dactilitis y el compromiso ungueal. Gracias a los avances en el entendimiento de su fisiopatología se ha logrado desarrollar en los últimos años un arsenal terapéutico suficiente para controlar la mayoría de sus dominios clínicos.
psoriásica关节炎(APs)是一种自身免疫性疾病相关的系统性牛皮癣,即现在在单称为光谱psoriásica,和其他疾病是心血管疾病、代谢综合征、肠道炎症临床,情绪障碍,慢性感染和风险最高。该病的关节受累表现异质性,包括外周关节和轴向关节,并伴有肠炎、手指炎和指甲受累等其他临床表现。由于对其病理生理学理解的进步,近年来已设法发展了一个治疗武器,足以控制其大多数临床领域。
{"title":"Conceptos actuales del diagnóstico y tratamiento de la artritis psoriásica","authors":"Juan Camilo Santacruz","doi":"10.47307/gmc.2023.131.3.19","DOIUrl":"https://doi.org/10.47307/gmc.2023.131.3.19","url":null,"abstract":"La artritis psoriásica (APs) es una enfermedad autoinmune sistémica asociada a la psoriasis, conocida ahora dentro de un único espectro llamado enfermedad psoriásica, y otras comorbilidades como lo son enfermedad cardiovascular, síndrome metabólico, inflamación intestinal subclínica, trastornos del estado de ánimo, mayor riesgo de infecciones crónicas y fibromialgia. El compromiso articular en esta enfermedad es de presentación heterogénea, incluyendo tanto las articulaciones periféricas como axiales, acompañadas de otras manifestaciones clínicas como lo son la presencia de entesitis, dactilitis y el compromiso ungueal. Gracias a los avances en el entendimiento de su fisiopatología se ha logrado desarrollar en los últimos años un arsenal terapéutico suficiente para controlar la mayoría de sus dominios clínicos.","PeriodicalId":12577,"journal":{"name":"Gaceta Médica de Caracas","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135308660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efectos de la inyección subdérmica de pentoxifilina en la integración de los injertos cutáneos de espesor total en un modelo animal 在动物模型中,己酮可可碱皮下注射对全厚皮肤移植整合的影响
Pub Date : 2023-09-16 DOI: 10.47307/gmc.2023.131.3.6
Linda Rincón-Rubio
Los injertos cutáneos son una herramienta ampliamente utilizada en el campo de la cirugía plástica y reconstructiva, por lo que es de gran importancia la búsqueda de técnicas que permitan una optimización de la integración de los mismos. Este estudio evaluó los efectos macro y microscópicos de la administración subdérmica de pentoxifilina (PTX) en la integración de los injertos cutáneos de espesor total. En un modelo experimental, controlado, aleatorizado, en 8 ratas, distribuidas en 2 grupos, 2 para control y 6 del ensayo experimental.
皮肤移植是一种广泛应用于整形和重建外科领域的工具,因此寻找能够优化其整合的技术是非常重要的。本研究的目的是评估皮下注射己酮茶碱(PTX)对全厚度皮肤移植整合的微观和微观影响。在实验模型中,8只大鼠随机对照,分为2组,2组为对照,6组为试验。
{"title":"Efectos de la inyección subdérmica de pentoxifilina en la integración de los injertos cutáneos de espesor total en un modelo animal","authors":"Linda Rincón-Rubio","doi":"10.47307/gmc.2023.131.3.6","DOIUrl":"https://doi.org/10.47307/gmc.2023.131.3.6","url":null,"abstract":"Los injertos cutáneos son una herramienta ampliamente utilizada en el campo de la cirugía plástica y reconstructiva, por lo que es de gran importancia la búsqueda de técnicas que permitan una optimización de la integración de los mismos. Este estudio evaluó los efectos macro y microscópicos de la administración subdérmica de pentoxifilina (PTX) en la integración de los injertos cutáneos de espesor total. En un modelo experimental, controlado, aleatorizado, en 8 ratas, distribuidas en 2 grupos, 2 para control y 6 del ensayo experimental.","PeriodicalId":12577,"journal":{"name":"Gaceta Médica de Caracas","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135307174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical features of patients with cancer of thoracic esophagus and results of their surgical treatment 胸段食管癌患者的临床特点及手术治疗效果
Pub Date : 2023-09-16 DOI: 10.47307/gmc.2023.131.3.7
Fariz Jamalov
Esophageal cancer takes one of the first places in the structure of morbidity and mortality among malignant diseases. The development of anesthesiology and thoracic resuscitation provided the evolution of the surgical method. Resections of the esophagus with locally-disseminated and complicated forms of cancer have become possible. But even today, the long-term results of surgical treatment don’t satisfy clinicians. Often this is due to the dissemination of the tumor process in most patients at the time of treatment. For this purpose, an analysis of clinical material was carried out, including 89 patients with cancer of thoracic part of esophagus, who underwent reconstructive surgeries (extirpation of the thoracic part of esophagus with simultaneous retromediastinal plasty by stomach tube) in the surgical unit of Republican Clinical Hospital (RCH), n.a. academic M.A.Mir-Gasimov, Baku city. Interventions on the esophagus were performed either of two approaches – upper median laparotomy and left-sided cervicotomy (76 patients – 85,4%) or from three-with the addition of a right sided lateral thoracotomy in the fifth intercostal space (13 patients – 14,6%). There were no deaths due to surgical complications. The fundamental possibility and reasonableness of performing expanded radical interventions has been detected, taking into account the technical resectability of the tumor, which is especially important in working with a group of patients with “late” esophageal cancer criteria, such as the age of the patient, the size of the primary tumors, its local dissemination are not a contraindication to radical surgery.
食管癌在恶性疾病的发病率和死亡率结构中居首位。麻醉学和胸腔复苏的发展促进了手术方法的发展。局部播散和复杂形式的食道癌切除术已经成为可能。但即使在今天,手术治疗的长期效果也不能让临床医生满意。这通常是由于大多数患者在治疗时肿瘤的扩散过程。为此,我们对89例在巴库市M.A.Mir-Gasimov共和国临床医院(RCH)外科接受重建手术(切除胸段食道并同时经胃管后纵隔成形术)的胸段食管癌患者的临床资料进行了分析。对食道进行干预的方法有两种,一种是上正中剖腹手术,另一种是左侧颈切开术(76例患者- 85,4%),另一种是在第五肋间隙加右侧外侧开胸术(13例患者- 14.6%)。没有因手术并发症而死亡。考虑到肿瘤的技术可切除性,已经发现了进行扩大根治性干预的基本可能性和合理性,这在治疗“晚期”食管癌患者时尤其重要,如患者的年龄、原发肿瘤的大小、其局部扩散不是根治性手术的禁忌症。
{"title":"Clinical features of patients with cancer of thoracic esophagus and results of their surgical treatment","authors":"Fariz Jamalov","doi":"10.47307/gmc.2023.131.3.7","DOIUrl":"https://doi.org/10.47307/gmc.2023.131.3.7","url":null,"abstract":"Esophageal cancer takes one of the first places in the structure of morbidity and mortality among malignant diseases. The development of anesthesiology and thoracic resuscitation provided the evolution of the surgical method. Resections of the esophagus with locally-disseminated and complicated forms of cancer have become possible. But even today, the long-term results of surgical treatment don’t satisfy clinicians. Often this is due to the dissemination of the tumor process in most patients at the time of treatment. For this purpose, an analysis of clinical material was carried out, including 89 patients with cancer of thoracic part of esophagus, who underwent reconstructive surgeries (extirpation of the thoracic part of esophagus with simultaneous retromediastinal plasty by stomach tube) in the surgical unit of Republican Clinical Hospital (RCH), n.a. academic M.A.Mir-Gasimov, Baku city. Interventions on the esophagus were performed either of two approaches – upper median laparotomy and left-sided cervicotomy (76 patients – 85,4%) or from three-with the addition of a right sided lateral thoracotomy in the fifth intercostal space (13 patients – 14,6%). There were no deaths due to surgical complications. The fundamental possibility and reasonableness of performing expanded radical interventions has been detected, taking into account the technical resectability of the tumor, which is especially important in working with a group of patients with “late” esophageal cancer criteria, such as the age of the patient, the size of the primary tumors, its local dissemination are not a contraindication to radical surgery.","PeriodicalId":12577,"journal":{"name":"Gaceta Médica de Caracas","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135307171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Eficacia de la citología, colposcopia y microcolpohisteroscopia en el diagnóstico de lesiones intraepiteliales de cuello uterino 细胞学、阴道镜和显微阴道宫腔镜诊断宫颈上皮内病变的有效性
Pub Date : 2023-09-16 DOI: 10.47307/gmc.2023.131.3.8
Claudia Leal Diaz
Introducción: La identificación temprana de lesiones preinvasoras de cuello uterino es fundamental y se realiza a través de procedimientos no invasivos. Objetivo: Evaluar la eficacia de la citología, colposcopia y microcolpohisteroscopia en el diagnóstico de lesiones intraepiteliales de cuello uterino. Método: Se realizó una investigación de carácter descriptivo observacional y transversal. Con población de 185 pacientes, mediante la elección de criterios de inclusión y de exclusión, se realizó selección intencional de la muestra que estuvo representada por 17 pacientes, los procedimientos se realizaron en cuatro fases en orden de citología, colposcopia, microcolpohisteroscopia para observar las características de las células en vivo y biopsia.
本文的目的是探讨宫颈癌的治疗方法,并探讨宫颈癌的治疗方法。宫颈上皮内病变的诊断是基于宫颈细胞学、阴道镜和显微阴道宫腔镜。方法:采用描述性、观察性和横断面研究方法。与人口185个病人,通过列入的标准选择和排斥,故意选择了显示程序是由17个病人,分四个阶段进行细胞学、colposcopia顺序、microcolpohisteroscopia去观察活细胞和活检的特点。
{"title":"Eficacia de la citología, colposcopia y microcolpohisteroscopia en el diagnóstico de lesiones intraepiteliales de cuello uterino","authors":"Claudia Leal Diaz","doi":"10.47307/gmc.2023.131.3.8","DOIUrl":"https://doi.org/10.47307/gmc.2023.131.3.8","url":null,"abstract":"Introducción: La identificación temprana de lesiones preinvasoras de cuello uterino es fundamental y se realiza a través de procedimientos no invasivos. Objetivo: Evaluar la eficacia de la citología, colposcopia y microcolpohisteroscopia en el diagnóstico de lesiones intraepiteliales de cuello uterino. Método: Se realizó una investigación de carácter descriptivo observacional y transversal. Con población de 185 pacientes, mediante la elección de criterios de inclusión y de exclusión, se realizó selección intencional de la muestra que estuvo representada por 17 pacientes, los procedimientos se realizaron en cuatro fases en orden de citología, colposcopia, microcolpohisteroscopia para observar las características de las células en vivo y biopsia.","PeriodicalId":12577,"journal":{"name":"Gaceta Médica de Caracas","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135308652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Gaceta Médica de Caracas
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1