Pub Date : 1900-01-01DOI: 10.4018/978-1-7998-2094-9.ch007
K. Mustafa, J. Kanwal, Samia Khakwani, Sara Musaddiq
Extensive research suggests that a number of plant-derived chemicals and traditional Oriental herbal remedies possess cognition-enhancing properties. Widely used current treatments for dementia include extracts of Ginkgo biloba and several alkaloidal, and therefore toxic, plant-derived cholinergic agents. Several non-toxic, European herbal species have pan-cultural traditions as treatments for cognitive deficits, including those associated with aging. Acute administration has also been found to reliably improve mnemonic performance in healthy young and elderly cohorts, whilst a chronic regime has been shown to attenuate cognitive declines in sufferers from Alzheimer's disease. The present chapter looks at the ethnobotanical and pharmacological importance of various plants cognitive enhancing and other neuroprotective abilities.
{"title":"Cognitive Enhancement and Neuroprotective Abilities of Plants","authors":"K. Mustafa, J. Kanwal, Samia Khakwani, Sara Musaddiq","doi":"10.4018/978-1-7998-2094-9.ch007","DOIUrl":"https://doi.org/10.4018/978-1-7998-2094-9.ch007","url":null,"abstract":"Extensive research suggests that a number of plant-derived chemicals and traditional Oriental herbal remedies possess cognition-enhancing properties. Widely used current treatments for dementia include extracts of Ginkgo biloba and several alkaloidal, and therefore toxic, plant-derived cholinergic agents. Several non-toxic, European herbal species have pan-cultural traditions as treatments for cognitive deficits, including those associated with aging. Acute administration has also been found to reliably improve mnemonic performance in healthy young and elderly cohorts, whilst a chronic regime has been shown to attenuate cognitive declines in sufferers from Alzheimer's disease. The present chapter looks at the ethnobotanical and pharmacological importance of various plants cognitive enhancing and other neuroprotective abilities.","PeriodicalId":126615,"journal":{"name":"Advanced Pharmacological Uses of Medicinal Plants and Natural Products","volume":"112 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127560931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.4018/978-1-7998-2094-9.ch016
R. Satpathy
Traditionally, the gum resin produced from the Boswellia serrata plant has been used in as a therapeutical compound. The gum that contains a chemical known as boswellic acid, AKBA (3-O-acetyl-11 keto-β-boswellic acid), and widely in ayurvedic medicines. This is used to treat the disease like reduction in various inflammatory conditions of the skin, eye, as well as respiratory disorders such as asthma, bronchitis, and laryngitis. The boswellic acids were also found capable to inhibit both hemolysis and chemotaxis of leukocytes and were shown to work by inhibiting C3-convertase, a key enzyme of the classical complementary pathway. In addition to this, the compound shows beneficial effects in various pharmacological properties like immunomodulation activity, polyarthritis, activity against Hepatitis C-virus and other harmful microbes, Colitis and Crohn's disease, and so on. The boswellic acid is also used to treat patients with memory disorders. In this chapter, the chemical nature and isolation of boswellic acid and its therapeutic importance have been highlighted.
{"title":"Therapeutic Importance and Application of Boswellic Acid From the Plant Boswellia serrata","authors":"R. Satpathy","doi":"10.4018/978-1-7998-2094-9.ch016","DOIUrl":"https://doi.org/10.4018/978-1-7998-2094-9.ch016","url":null,"abstract":"Traditionally, the gum resin produced from the Boswellia serrata plant has been used in as a therapeutical compound. The gum that contains a chemical known as boswellic acid, AKBA (3-O-acetyl-11 keto-β-boswellic acid), and widely in ayurvedic medicines. This is used to treat the disease like reduction in various inflammatory conditions of the skin, eye, as well as respiratory disorders such as asthma, bronchitis, and laryngitis. The boswellic acids were also found capable to inhibit both hemolysis and chemotaxis of leukocytes and were shown to work by inhibiting C3-convertase, a key enzyme of the classical complementary pathway. In addition to this, the compound shows beneficial effects in various pharmacological properties like immunomodulation activity, polyarthritis, activity against Hepatitis C-virus and other harmful microbes, Colitis and Crohn's disease, and so on. The boswellic acid is also used to treat patients with memory disorders. In this chapter, the chemical nature and isolation of boswellic acid and its therapeutic importance have been highlighted.","PeriodicalId":126615,"journal":{"name":"Advanced Pharmacological Uses of Medicinal Plants and Natural Products","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116438745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.4018/978-1-7998-2094-9.ch009
N. Babu, Ajeet Singh, Navneet
Medicinal plants have been necessary to conventional and non-customary types of prescriptions dating back to somewhere around 5000 years ago. Researchers progressively depend on current logical techniques and proof-based medication to demonstrate the viability of herbal medicines and spotlight on a better comprehension of the systems of their activity. Notwithstanding, data concerning quantitative human health advantages on natural remedies is yet uncommon, constraining their legitimate valuation. Traditional medicines are regularly utilized for the wound-healing process covering a wide zone of various skin-related infections. This chapter will give information about the wound-healing capability of plants that are useful for the advancement of new wound-healing formulations.
{"title":"Traditional Herbs With Potential Wound Healing Properties","authors":"N. Babu, Ajeet Singh, Navneet","doi":"10.4018/978-1-7998-2094-9.ch009","DOIUrl":"https://doi.org/10.4018/978-1-7998-2094-9.ch009","url":null,"abstract":"Medicinal plants have been necessary to conventional and non-customary types of prescriptions dating back to somewhere around 5000 years ago. Researchers progressively depend on current logical techniques and proof-based medication to demonstrate the viability of herbal medicines and spotlight on a better comprehension of the systems of their activity. Notwithstanding, data concerning quantitative human health advantages on natural remedies is yet uncommon, constraining their legitimate valuation. Traditional medicines are regularly utilized for the wound-healing process covering a wide zone of various skin-related infections. This chapter will give information about the wound-healing capability of plants that are useful for the advancement of new wound-healing formulations.","PeriodicalId":126615,"journal":{"name":"Advanced Pharmacological Uses of Medicinal Plants and Natural Products","volume":"84 5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127982836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.4018/978-1-7998-2094-9.ch002
Manish Singh Sansi, Daraksha Iram, K. Narayan, Sandeep Kumar, O. Prakash, D. Misra
Diabetes mellitus (DM) is a chronic disease caused by inherited or acquired deficiency in insulin secretion and by decreased insulin secretion by the organ. Insulin deficiency causes the DM. Synthetic drugs are widely used in the treatment of diabetes, but they have some side effects. The antihyperglycemic and antihyperlipedemic effects of the plants are related to their ability to maintain pancreatic function. Medicinal plants constituents such as glycosides, alkaloids, terpenoids, and flavonoids mitigate DM. B. ciliata inhibits the α-glucosidase and α-amylase. Cinnamon extracts improve insulin receptor function by activating insulin receptor kinase and inhibiting insulin receptor phosphatase, which lead to an increase in insulin sensitivity. Morinda lucida also had the highest antioxidant activity, and it also inhibited the α-glucosidase. Many plants have also been shown to antihyperlipedemic effects. Finally, it can be concluded that medicinal plants have that ability to treat or prevent DM.
{"title":"Antidiabetic Activity (Anti-Hyperglycemic Activity, Anti-Hyperlipidemic Activity)/Agents From Medicinal Plants","authors":"Manish Singh Sansi, Daraksha Iram, K. Narayan, Sandeep Kumar, O. Prakash, D. Misra","doi":"10.4018/978-1-7998-2094-9.ch002","DOIUrl":"https://doi.org/10.4018/978-1-7998-2094-9.ch002","url":null,"abstract":"Diabetes mellitus (DM) is a chronic disease caused by inherited or acquired deficiency in insulin secretion and by decreased insulin secretion by the organ. Insulin deficiency causes the DM. Synthetic drugs are widely used in the treatment of diabetes, but they have some side effects. The antihyperglycemic and antihyperlipedemic effects of the plants are related to their ability to maintain pancreatic function. Medicinal plants constituents such as glycosides, alkaloids, terpenoids, and flavonoids mitigate DM. B. ciliata inhibits the α-glucosidase and α-amylase. Cinnamon extracts improve insulin receptor function by activating insulin receptor kinase and inhibiting insulin receptor phosphatase, which lead to an increase in insulin sensitivity. Morinda lucida also had the highest antioxidant activity, and it also inhibited the α-glucosidase. Many plants have also been shown to antihyperlipedemic effects. Finally, it can be concluded that medicinal plants have that ability to treat or prevent DM.","PeriodicalId":126615,"journal":{"name":"Advanced Pharmacological Uses of Medicinal Plants and Natural Products","volume":"91 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124692356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.4018/978-1-7998-2094-9.ch012
Anuradha Singh
Curcumin, the polyphenol natural product, is a constituent of the traditional medicine known as turmeric. Extensive research over the last 50 years has indicated that this polyphenol displays potent pharmacological effects by targeting many critical cellular factors through a diverse array of mechanisms of action. However, there are some obstacles that prevent this wonder molecule to be effective in clinical settings and limit its use to topical applications only. Curcumin has recently been classified as both PAINS (panassay interference compounds) and an IMPS (invalid metabolic panaceas) candidate. Due to likely false activity of curcumin in vitro and in vivo has resulted unsuccessful clinical trial of curcumin against several disease. The chapter will review the essential medicinal chemistry of curcumin as well as envisage a compilation and discussion on the poor bioavailability of curcumin.
{"title":"Pharmacological Properties of Curcumin","authors":"Anuradha Singh","doi":"10.4018/978-1-7998-2094-9.ch012","DOIUrl":"https://doi.org/10.4018/978-1-7998-2094-9.ch012","url":null,"abstract":"Curcumin, the polyphenol natural product, is a constituent of the traditional medicine known as turmeric. Extensive research over the last 50 years has indicated that this polyphenol displays potent pharmacological effects by targeting many critical cellular factors through a diverse array of mechanisms of action. However, there are some obstacles that prevent this wonder molecule to be effective in clinical settings and limit its use to topical applications only. Curcumin has recently been classified as both PAINS (panassay interference compounds) and an IMPS (invalid metabolic panaceas) candidate. Due to likely false activity of curcumin in vitro and in vivo has resulted unsuccessful clinical trial of curcumin against several disease. The chapter will review the essential medicinal chemistry of curcumin as well as envisage a compilation and discussion on the poor bioavailability of curcumin.","PeriodicalId":126615,"journal":{"name":"Advanced Pharmacological Uses of Medicinal Plants and Natural Products","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129747397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.4018/978-1-7998-2094-9.ch003
K. Mustafa, J. Kanwal, Sara Musaddiq, Samia Khakwani
The primary aim of this study is to access the salient herbal plants with the active constituent of potentially anti-hair fall activities. It also presents the various reasons behind hair loss ailments. As part of this study, a focus is placed on active phytochemicals within these medicinal plants or natural products in terms of various hair fall disease treatments. As natural products have a beneficial effect to minimize hair loss and have promoted the potential for new hair growth, it presents the medicinal values of natural plants in reference to safety and effectiveness for health.
{"title":"Ethnobotanical and Pharmacological Importance of the Herbal Plants With Anti-Hair Fall and Hair Growth Activities","authors":"K. Mustafa, J. Kanwal, Sara Musaddiq, Samia Khakwani","doi":"10.4018/978-1-7998-2094-9.ch003","DOIUrl":"https://doi.org/10.4018/978-1-7998-2094-9.ch003","url":null,"abstract":"The primary aim of this study is to access the salient herbal plants with the active constituent of potentially anti-hair fall activities. It also presents the various reasons behind hair loss ailments. As part of this study, a focus is placed on active phytochemicals within these medicinal plants or natural products in terms of various hair fall disease treatments. As natural products have a beneficial effect to minimize hair loss and have promoted the potential for new hair growth, it presents the medicinal values of natural plants in reference to safety and effectiveness for health.","PeriodicalId":126615,"journal":{"name":"Advanced Pharmacological Uses of Medicinal Plants and Natural Products","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125491005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.4018/978-1-7998-2094-9.ch004
A. Bhat, H. Sharma
Medicines of plant origin have been used for treating humans and animals without any adverse effects. New medicinal plants are searched to develop more effective and cheaper drugs in place of synthetics drugs. Plants represent a large natural source of compounds that might serve for the development of novel drugs. Currently medicinal herbs are researched for diuretic properties, and several medicinal herbs are used as diuretics. Currently various synthetic medicines are available for this purpose; however, natural resource medicines are still an important choice because of their higher efficiency and better safety. Further, some herbs are also important sources of antioxidants, which protect the body from the effects of free radicals produced in the body. Antioxidants are required by our body due to increase in the likely exposure of the body to harmful pollutants, radiation, UV lights, etc. These have the ability to delay the oxidation, and plant-derived products are of great interest due to the adverse effect of antibiotics.
{"title":"Medicinal Plants","authors":"A. Bhat, H. Sharma","doi":"10.4018/978-1-7998-2094-9.ch004","DOIUrl":"https://doi.org/10.4018/978-1-7998-2094-9.ch004","url":null,"abstract":"Medicines of plant origin have been used for treating humans and animals without any adverse effects. New medicinal plants are searched to develop more effective and cheaper drugs in place of synthetics drugs. Plants represent a large natural source of compounds that might serve for the development of novel drugs. Currently medicinal herbs are researched for diuretic properties, and several medicinal herbs are used as diuretics. Currently various synthetic medicines are available for this purpose; however, natural resource medicines are still an important choice because of their higher efficiency and better safety. Further, some herbs are also important sources of antioxidants, which protect the body from the effects of free radicals produced in the body. Antioxidants are required by our body due to increase in the likely exposure of the body to harmful pollutants, radiation, UV lights, etc. These have the ability to delay the oxidation, and plant-derived products are of great interest due to the adverse effect of antibiotics.","PeriodicalId":126615,"journal":{"name":"Advanced Pharmacological Uses of Medicinal Plants and Natural Products","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115987338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.4018/978-1-7998-2094-9.ch013
Sandeep Kumar, A. Hussain, Manish Singh Sansi, Daraksha Iram, Priyanka, A. Vats
The medicinal plants have been used by humans since ancient times, and the great civilizations of the world in ancient times were well aware of the benefits brought by the use of medicinal plants. This chapter provides important information regarding medicinal plants that have a wide variety of antioxidative agents ranging from bitter compounds that stimulate digestion system, phenolic compounds for antioxidant and numerous other pharmacological properties, antibacterial, and antifungal to tannins that act as natural antibiotics, diuretic substances, alkaloids, and so forth.
{"title":"Antioxidative Agents From Medicinal Plants","authors":"Sandeep Kumar, A. Hussain, Manish Singh Sansi, Daraksha Iram, Priyanka, A. Vats","doi":"10.4018/978-1-7998-2094-9.ch013","DOIUrl":"https://doi.org/10.4018/978-1-7998-2094-9.ch013","url":null,"abstract":"The medicinal plants have been used by humans since ancient times, and the great civilizations of the world in ancient times were well aware of the benefits brought by the use of medicinal plants. This chapter provides important information regarding medicinal plants that have a wide variety of antioxidative agents ranging from bitter compounds that stimulate digestion system, phenolic compounds for antioxidant and numerous other pharmacological properties, antibacterial, and antifungal to tannins that act as natural antibiotics, diuretic substances, alkaloids, and so forth.","PeriodicalId":126615,"journal":{"name":"Advanced Pharmacological Uses of Medicinal Plants and Natural Products","volume":"282 2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121117948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.4018/978-1-7998-2094-9.ch017
A. Gautam
Phytochemicals have recently been studied in vivo for their unmatched interactions in curing lethal diseases that can't be cured by allopathic medical intervention without any adverse effect on the patient health. These methods were being used in ancient India, where Jamun and Giloy have been used to decrease hormonal imbalance and pathological disorders. Signaling pathways of the active components of Tinospora cordifolia thus enable effective disease targeting. With so much to offer to the scientific world of medicine, the plant Tinospora truly acts as an incredible source as it deals with seasonal fever like Dengue, Malaria, Chickengunia, and anticancer and anti-HIV (research undergoing). Whereas the Syzygium cumini (Jamun) fruit and seed hold worth in treating various diet-related malfunctions, especially hyperglycemia. In the current research, Jamun seed and fruit extracts have been proved effective in the regulation of blood glucose and insulin parameters.
{"title":"Therapeutic Properties of Syzygium cumini (Jamun) and Tinospora cordifolia (Giloy) Against Various Lethal Diseases","authors":"A. Gautam","doi":"10.4018/978-1-7998-2094-9.ch017","DOIUrl":"https://doi.org/10.4018/978-1-7998-2094-9.ch017","url":null,"abstract":"Phytochemicals have recently been studied in vivo for their unmatched interactions in curing lethal diseases that can't be cured by allopathic medical intervention without any adverse effect on the patient health. These methods were being used in ancient India, where Jamun and Giloy have been used to decrease hormonal imbalance and pathological disorders. Signaling pathways of the active components of Tinospora cordifolia thus enable effective disease targeting. With so much to offer to the scientific world of medicine, the plant Tinospora truly acts as an incredible source as it deals with seasonal fever like Dengue, Malaria, Chickengunia, and anticancer and anti-HIV (research undergoing). Whereas the Syzygium cumini (Jamun) fruit and seed hold worth in treating various diet-related malfunctions, especially hyperglycemia. In the current research, Jamun seed and fruit extracts have been proved effective in the regulation of blood glucose and insulin parameters.","PeriodicalId":126615,"journal":{"name":"Advanced Pharmacological Uses of Medicinal Plants and Natural Products","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114187033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.4018/978-1-7998-2094-9.ch008
M. Dwivedi, P. Singh
Malaria is a life-threatening infectious disease caused by a protozoan parasite of the genus Plasmodium. It is transmitted through the bites of infected female Anopheles mosquitoes. The global burden is estimated to be around 219 million cases in 87 countries. Natural compounds have been used primarily in the traditional medicine for thousands of years. For the treatment of malaria, natural products were used until the development of synthetic drugs, and most of the currently available anti-malarial drugs have been derived based on the compounds from these traditional medicinal plants. The current chapter tries to briefly indicate the emerging resistance against anti-malarial drugs and to discuss the recent research on natural products that have been evaluated for anti-malarial activity. Rigorous evaluation of the efficacy and safety of traditional medicines is required along with identification of active constituents in order to develop new drugs with novel mechanisms of action.
{"title":"Anti-Malarial Drug Resistance","authors":"M. Dwivedi, P. Singh","doi":"10.4018/978-1-7998-2094-9.ch008","DOIUrl":"https://doi.org/10.4018/978-1-7998-2094-9.ch008","url":null,"abstract":"Malaria is a life-threatening infectious disease caused by a protozoan parasite of the genus Plasmodium. It is transmitted through the bites of infected female Anopheles mosquitoes. The global burden is estimated to be around 219 million cases in 87 countries. Natural compounds have been used primarily in the traditional medicine for thousands of years. For the treatment of malaria, natural products were used until the development of synthetic drugs, and most of the currently available anti-malarial drugs have been derived based on the compounds from these traditional medicinal plants. The current chapter tries to briefly indicate the emerging resistance against anti-malarial drugs and to discuss the recent research on natural products that have been evaluated for anti-malarial activity. Rigorous evaluation of the efficacy and safety of traditional medicines is required along with identification of active constituents in order to develop new drugs with novel mechanisms of action.","PeriodicalId":126615,"journal":{"name":"Advanced Pharmacological Uses of Medicinal Plants and Natural Products","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115213076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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