Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6484
J. Bousamaki, A. Petersen, D. Bozzini, A. M. Arraut, H. H. Hansen, M. Feigh
{"title":"High-fat Diet Feeding Promotes More Severe and Durable Lung Fibrotic Injury in a Bleomycin-induced and Spirometry-confirmed Mouse Model of Idiopathic Pulmonary Fibrosis (IPF)","authors":"J. Bousamaki, A. Petersen, D. Bozzini, A. M. Arraut, H. H. Hansen, M. Feigh","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6484","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6484","url":null,"abstract":"","PeriodicalId":131392,"journal":{"name":"D29. TRANSLATIONAL RESEARCH IN IPF","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123586820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6473
N. Assadinia, A. Moran-Macdonald, K. Wu, K. Ikezoe, S. Ledoux, J. Cooper, J. Hogg, D. Vasilescu, T. Hackett
{"title":"Remodeling of Small Airways and Associated Arterial Vasculature Is a Hallmark of Idiopathic Pulmonary Fibrosis","authors":"N. Assadinia, A. Moran-Macdonald, K. Wu, K. Ikezoe, S. Ledoux, J. Cooper, J. Hogg, D. Vasilescu, T. Hackett","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6473","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6473","url":null,"abstract":"","PeriodicalId":131392,"journal":{"name":"D29. TRANSLATIONAL RESEARCH IN IPF","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115227264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6493
L. Bhat, S. Bhat, Marie-Claude Nault, M. Biernat, S. Labbé
{"title":"Brilaroxazine Efficacy in a Bleomycin-induced Rodent Model of Idiopathic Pulmonary Fibrosis","authors":"L. Bhat, S. Bhat, Marie-Claude Nault, M. Biernat, S. Labbé","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6493","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6493","url":null,"abstract":"","PeriodicalId":131392,"journal":{"name":"D29. TRANSLATIONAL RESEARCH IN IPF","volume":"102 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122816723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6472
M. Nizamoglu, F. Alleblas, T. Koster, J. Vonk, M. Thomas, E.S. White, W. Timens, C. K. Watson, K. E. El Kasmi, B. Melgert, I. Heijink, J. Burgess
{"title":"Primary Human Lung Fibroblasts Alter Collagen Fiber Structure in 3-D Lung Extracellular Matrix-derived Hydrogels in Response to a Fibrotic Microenvironment","authors":"M. Nizamoglu, F. Alleblas, T. Koster, J. Vonk, M. Thomas, E.S. White, W. Timens, C. K. Watson, K. E. El Kasmi, B. Melgert, I. Heijink, J. Burgess","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6472","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6472","url":null,"abstract":"","PeriodicalId":131392,"journal":{"name":"D29. TRANSLATIONAL RESEARCH IN IPF","volume":"159 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124715053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6477
P. Rajasekar, A. Lagan, J. Patel, B. Barksby, R. Burgoyne, J. MacIssac, D. Lin, S.T. May, M. Castellanos-Uribe, M. Kobor, T. Hackett, A. Halayko, A. Knox, A. Fisher, L. Borthwick, R. Clifford
{"title":"Distinct Idiopathic Pulmonary Fibrosis Associated Transcriptome and Methylome Changes in Airway and Parenchymal Fibroblasts","authors":"P. Rajasekar, A. Lagan, J. Patel, B. Barksby, R. Burgoyne, J. MacIssac, D. Lin, S.T. May, M. Castellanos-Uribe, M. Kobor, T. Hackett, A. Halayko, A. Knox, A. Fisher, L. Borthwick, R. Clifford","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6477","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6477","url":null,"abstract":"","PeriodicalId":131392,"journal":{"name":"D29. TRANSLATIONAL RESEARCH IN IPF","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125563532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6478
C. Prasad, A. Srinivasan, I. Sundar
{"title":"Potential Role of Circadian Clock Modulator in Bleomycin-induced Pulmonary Fibrosis","authors":"C. Prasad, A. Srinivasan, I. Sundar","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6478","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6478","url":null,"abstract":"","PeriodicalId":131392,"journal":{"name":"D29. TRANSLATIONAL RESEARCH IN IPF","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117254335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6476
K. Suzuki, F. Namai, N. Nomura, Y. Sato, A. Kotsugai, T. Shimosato, T. Sato
{"title":"Effect of Local Intratracheal Therapy Using Particleized Nintedanib in a Murine Model of Pulmonary Fibrosis","authors":"K. Suzuki, F. Namai, N. Nomura, Y. Sato, A. Kotsugai, T. Shimosato, T. Sato","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6476","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6476","url":null,"abstract":"","PeriodicalId":131392,"journal":{"name":"D29. TRANSLATIONAL RESEARCH IN IPF","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125261724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6482
M. Koloko Ngassie, B. Roos, A. Koenig-Kappes, C. Pabelick, R. Gosens, C. Brandsma, J. Burgess, Y. Prakash
{"title":"Endoplasmic Reticulum Stress Induces Cellular Senescence in Human Lung Fibroblasts","authors":"M. Koloko Ngassie, B. Roos, A. Koenig-Kappes, C. Pabelick, R. Gosens, C. Brandsma, J. Burgess, Y. Prakash","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6482","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6482","url":null,"abstract":"","PeriodicalId":131392,"journal":{"name":"D29. TRANSLATIONAL RESEARCH IN IPF","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114873729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6488
K. Kirov, M. Thillai, A. Ruggiero, H. Manners, F. Kanavati, F. Blé, K. Ostridge, T. M. Maher, P. Molyneaux
{"title":"Automated Image Analysis of Vascular and Fibrotic Lung Volumes Shows Association With IPF Mortality","authors":"K. Kirov, M. Thillai, A. Ruggiero, H. Manners, F. Kanavati, F. Blé, K. Ostridge, T. M. Maher, P. Molyneaux","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6488","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6488","url":null,"abstract":"","PeriodicalId":131392,"journal":{"name":"D29. TRANSLATIONAL RESEARCH IN IPF","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115161194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6481
A. Saxton, A. Chang, C. Cribbs, N. Franks, J. Valdoz, S. Garfield, D. Downs, H. Hepworth, M. Kobe, M. Scholand, G. Raghu, S. Narayanan, P. V. Van Ry
{"title":"Developing Decellularized Tissue Hydrogel as a Culture Supplement for Building a Pulmonary Fibrosis Organoid Model","authors":"A. Saxton, A. Chang, C. Cribbs, N. Franks, J. Valdoz, S. Garfield, D. Downs, H. Hepworth, M. Kobe, M. Scholand, G. Raghu, S. Narayanan, P. V. Van Ry","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6481","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6481","url":null,"abstract":"","PeriodicalId":131392,"journal":{"name":"D29. TRANSLATIONAL RESEARCH IN IPF","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116945689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}