{"title":"1,6-dinitropyrene.","authors":"","doi":"10.32388/h5jg9k","DOIUrl":"https://doi.org/10.32388/h5jg9k","url":null,"abstract":"","PeriodicalId":13187,"journal":{"name":"IARC monographs on the evaluation of carcinogenic risks to humans","volume":"18 1","pages":"215-30"},"PeriodicalIF":0.0,"publicationDate":"2020-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83757053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Furan.","authors":"","doi":"10.32388/schiop","DOIUrl":"https://doi.org/10.32388/schiop","url":null,"abstract":"","PeriodicalId":13187,"journal":{"name":"IARC monographs on the evaluation of carcinogenic risks to humans","volume":"487 1","pages":"393-407"},"PeriodicalIF":0.0,"publicationDate":"2020-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77052031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Coumarin (1,2-benzopyrone) has a bitter-sweet odor, and is present in tonka beans, sweet clover, lavender and citrus oils, and several other plant species. It is widely used as a fragrance in perfumes, cosmetics, personal care, and other products. It has industrial uses in the electroplating and pharmaceutical industries, and is also used to mask odors in paints, printing inks, insecticides, plastics, and synthetic rubbers. Because of its industrial uses and its many uses as a fragrance in consumer products, workers in a variety of occupations and the general public are exposed to coumarin.
{"title":"Coumarin.","authors":"","doi":"10.32388/am52kf","DOIUrl":"https://doi.org/10.32388/am52kf","url":null,"abstract":"Coumarin (1,2-benzopyrone) has a bitter-sweet odor, and is present in tonka beans, sweet clover, lavender and citrus oils, and several other plant species. It is widely used as a fragrance in perfumes, cosmetics, personal care, and other products. It has industrial uses in the electroplating and pharmaceutical industries, and is also used to mask odors in paints, printing inks, insecticides, plastics, and synthetic rubbers. Because of its industrial uses and its many uses as a fragrance in consumer products, workers in a variety of occupations and the general public are exposed to coumarin.","PeriodicalId":13187,"journal":{"name":"IARC monographs on the evaluation of carcinogenic risks to humans","volume":"61 1","pages":"193-225"},"PeriodicalIF":0.0,"publicationDate":"2020-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83306951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"2-Nitroanisole.","authors":"","doi":"10.32388/i4x3s4","DOIUrl":"https://doi.org/10.32388/i4x3s4","url":null,"abstract":"","PeriodicalId":13187,"journal":{"name":"IARC monographs on the evaluation of carcinogenic risks to humans","volume":"32 3 1","pages":"369-80"},"PeriodicalIF":0.0,"publicationDate":"2020-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90535235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"6-nitrochrysene.","authors":"","doi":"10.32388/ehqq4r","DOIUrl":"https://doi.org/10.32388/ehqq4r","url":null,"abstract":"","PeriodicalId":13187,"journal":{"name":"IARC monographs on the evaluation of carcinogenic risks to humans","volume":"54 1","pages":"267-76"},"PeriodicalIF":0.0,"publicationDate":"2020-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72645423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A glucose-linked chloroethylnitrosourea with potential antineoplastic activity. Chlorozotocin alkylates DNA and proteins, induces the formation of interstrand DNA and DNA-protein crosslinks, and causes DNA strand breakage, thereby damaging DNA and resulting in cell death. This agent has been shown to exhibit antitumor and immunomodulatory effects in cell lines and animal models. Chlorozotocin is a mutagen and is less myelotoxic than other nitrosoureas. (NCI04)
{"title":"Chlorozotocin.","authors":"","doi":"10.32388/4cv3xn","DOIUrl":"https://doi.org/10.32388/4cv3xn","url":null,"abstract":"A glucose-linked chloroethylnitrosourea with potential antineoplastic activity. Chlorozotocin alkylates DNA and proteins, induces the formation of interstrand DNA and DNA-protein crosslinks, and causes DNA strand breakage, thereby damaging DNA and resulting in cell death. This agent has been shown to exhibit antitumor and immunomodulatory effects in cell lines and animal models. Chlorozotocin is a mutagen and is less myelotoxic than other nitrosoureas. (NCI04)","PeriodicalId":13187,"journal":{"name":"IARC monographs on the evaluation of carcinogenic risks to humans","volume":"28 1","pages":"65-75"},"PeriodicalIF":0.0,"publicationDate":"2020-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79377708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-27DOI: 10.1007/978-3-642-41714-6_32615
S. Kawatra
{"title":"Coal dust.","authors":"S. Kawatra","doi":"10.1007/978-3-642-41714-6_32615","DOIUrl":"https://doi.org/10.1007/978-3-642-41714-6_32615","url":null,"abstract":"","PeriodicalId":13187,"journal":{"name":"IARC monographs on the evaluation of carcinogenic risks to humans","volume":"2 1","pages":"337-406"},"PeriodicalIF":0.0,"publicationDate":"2020-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86263528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-17DOI: 10.1201/9780203735398-53
{"title":"Cyclohexanone.","authors":"","doi":"10.1201/9780203735398-53","DOIUrl":"https://doi.org/10.1201/9780203735398-53","url":null,"abstract":"","PeriodicalId":13187,"journal":{"name":"IARC monographs on the evaluation of carcinogenic risks to humans","volume":"18 1","pages":"157-69"},"PeriodicalIF":0.0,"publicationDate":"2019-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73641551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
At room temperature methyl bromide is a colourless gas, and in low concentrations odourless. It is used as a reaction gas in ionization chambers, for defatting wool and for extracting fats and ethereal oils from nuts, seeds and flowers. It is mainly used, however, as a fumigant in the production, improvement, storage and transport of foodstuffs; such fumigation is prescribed for export of the goods to various countries (e.g. the USA) (see GefStoffV 2003, § 15d). Another important application is in the disinfection of soil. Its use as a fire-extinguishing agent is obsolete (Budavari 1989, Hallier 1996).
{"title":"Methyl bromide.","authors":"Methyl Bromide, A. Cepted","doi":"10.1201/b10505-107","DOIUrl":"https://doi.org/10.1201/b10505-107","url":null,"abstract":"At room temperature methyl bromide is a colourless gas, and in low concentrations odourless. It is used as a reaction gas in ionization chambers, for defatting wool and for extracting fats and ethereal oils from nuts, seeds and flowers. It is mainly used, however, as a fumigant in the production, improvement, storage and transport of foodstuffs; such fumigation is prescribed for export of the goods to various countries (e.g. the USA) (see GefStoffV 2003, § 15d). Another important application is in the disinfection of soil. Its use as a fire-extinguishing agent is obsolete (Budavari 1989, Hallier 1996).","PeriodicalId":13187,"journal":{"name":"IARC monographs on the evaluation of carcinogenic risks to humans","volume":"62 1","pages":"721-35"},"PeriodicalIF":0.0,"publicationDate":"2019-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77588646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-17DOI: 10.1201/9780203735398-70
{"title":"Dimethylformamide.","authors":"","doi":"10.1201/9780203735398-70","DOIUrl":"https://doi.org/10.1201/9780203735398-70","url":null,"abstract":"","PeriodicalId":13187,"journal":{"name":"IARC monographs on the evaluation of carcinogenic risks to humans","volume":"10 1","pages":"545-74"},"PeriodicalIF":0.0,"publicationDate":"2019-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76239902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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