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Thermometry: A simple objective method for burn depth assessment 测温法:一种简单客观的烧伤深度评估方法
Pub Date : 2018-01-01 DOI: 10.4103/ijb.ijb_19_18
P. Agarwal, D. Sharma, Sudesh Wankhede, Lokesh Kumar Patel
Introduction: Accurate assessment of burn wound depth is important because it determines the choice of treatment and prognosis. Clinical evaluation remains the most commonly used modality with its accuracy varies from 50% to 70%. This study was conducted to assess the accuracy and feasibility of burn wound depth using noninvasive noncontact technique using infrared thermometry. Materials and Methods: Fifteen patients' burn wounds depth was classified clinically into full-thickness, deep partial-thickness, or superficial partial-thickness burns. Thermometry was performed on 3rd day of burn injury using the handheld infrared thermometer. A punch biopsy was taken from all three areas (deep, deep-partial, and superficial-partial burns). A correlation between surface temperature and depth of burn by histopathology was done. Results: 12/15 patients total burn surface area (TBSA < 65%) survived and three patients (TBSA > 65%) died. In 11/12survivors, thermometry correctly predicted final burn depth. One of 12 burns superficial burn was wrongly assessed clinically as full thickness but was correctly classified by thermometry and healed within 21 days without surgery. 3/12 burns on clinical assessment thought to be superficial were deep; two were correctly predicted by thermometry. Conclusions: Handheld infrared thermometer can be used in conjunction with clinical examination to improve the efficacy of burn wound depth assessment.
准确评估烧伤创面深度非常重要,因为它决定了治疗的选择和预后。临床评估仍然是最常用的方式,其准确性从50%到70%不等。本研究旨在评估使用红外测温仪的无创非接触技术测量烧伤创面深度的准确性和可行性。材料与方法:将15例患者的烧伤创面深度临床分为全层烧伤、深部分厚度烧伤和浅部分厚度烧伤。烧伤第3天采用手持式红外体温计测温。从所有三个区域(深度、深度部分和浅表部分烧伤)进行穿刺活检。组织病理学分析了烧伤表面温度与烧伤深度的关系。结果:12/15患者(TBSA < 65%)存活,3例(TBSA < 65%)死亡。在11/12幸存者中,测温准确地预测了最终的烧伤深度。在12例烧伤中,1例浅表烧伤在临床上被错误地评估为全厚度,但通过体温测量正确分类,并在21天内愈合,无需手术。3/12的烧伤经临床评估认为为浅表的为深度烧伤;其中两个是通过测温准确预测的。结论:手持式红外体温计可与临床检查相结合,提高烧伤创面深度评估的效果。
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引用次数: 4
Reconstruction of postburn crippled hands: A study of functional outcome 烧伤后残废手的重建:功能结果的研究
Pub Date : 2018-01-01 DOI: 10.4103/ijb.ijb_20_18
N. C. Hariharan, R. Sridhar, B. Sankari, V Valarmathy, Ebanesar Asirvatham, K. Geetha
Introduction: In postburn survivors, quality of life depends on the functional ability of one's hands. However, restoring useful function in crippled hands is a formidable challenge. Understandably in such cases, there are no standardized rules regarding the sequence of release, the type of skin cover, the duration of immobilization by K wires, and the intensity of hand therapy. Patients and Methods: We formulated a protocol and evaluated the outcome for cases of severe contractures with a total loss of hand function and distorted hand architecture. It is a cross-sectional study of 10 consecutive patients and 14 hands operated in our department from January 2014 to June 2017. The patients were operated in two stages. At the first stage, contractures of the wrist, dorsum, and thumb web space were released. Extension contractures of the fingers and thumb were also released. During the second stage, the contractures of the palm, volar aspect of the fingers, and web spaces were released. In both the stages, the fingers were maintained in released position for 3 weeks by K wires and the raw areas were covered with split skin graft/skin flap. Results: Patients were assessed for the improvement of hand function by the disabilities of the arm, shoulder and hand (DASH) scores of the 10 patients operated, four returned to the original employment/school. Four found meaningful employment. Conclusion: The aim in crippled hands is to restore useful function in the least number of stages rather than improving the range of movement in individual joints. Maintaining the release achieved by surgery with K wires, coupled with aggressive therapy, prevent the recurrence of the contractures.
在烧伤后幸存者中,生活质量取决于手的功能能力。然而,让残废的手恢复有用的功能是一项艰巨的挑战。可以理解的是,在这种情况下,关于释放的顺序、皮肤覆盖的类型、K针固定的持续时间和手部治疗的强度没有标准化的规则。患者和方法:我们制定了一项方案,并评估了严重挛缩伴手部功能完全丧失和手部结构扭曲的病例的结果。本研究是对2014年1月至2017年6月在我科连续手术的10例患者和14只手进行横断面研究。手术分两个阶段进行。在第一阶段,解除腕部、背部和拇指指蹼的挛缩。手指和拇指的伸展挛缩也得到了缓解。在第二阶段,手掌挛缩、手指掌侧和指蹼被解除。在这两个阶段,用K丝将手指保持在松开位置3周,并用裂开的皮肤移植物/皮瓣覆盖裸露区域。结果:通过10例手术患者的臂肩手残障(DASH)评分来评估患者手功能的改善情况,4例患者恢复到原来的工作/学校。其中四人找到了有意义的工作。结论:残废手的目的是在最少的阶段内恢复有用的功能,而不是提高单个关节的活动范围。通过K针手术保持松解,配合积极治疗,可防止挛缩复发。
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引用次数: 5
Exfoliative diseases of the integument and mucous membrane that mimic deep 2nd-degree burns with or without sepsis 类似深二度烧伤伴或不伴脓毒症的被膜和粘膜剥脱性疾病
Pub Date : 2018-01-01 DOI: 10.4103/ijb.ijb_28_18
K. Ramakrishnan, B. Ramachandran, K. Ravikumar, R. Ramkumar, V. Jayaraman, T. Mathivanan
Introduction: Exfoliative skin diseases in children can mimic burns in many ways and require early diagnosis and management. Here we enumerate the different skin conditions with four case based examples and their management. Clinical Presentation: Varying degrees of skin involvement may be seen with severe involvement in DRESS syndrome and milder involvement in Stevens-Johnson syndrome. Management: The management of this exfoliative lesion is the application of collagen membrane to the wound as we treat burns. Although systemic symptoms can produce mortality (e.g., dress), collagen dressing heals the wound well with good epithelialization. Early and appropriate antibiotic therapy is mandatory. Conclusion: Careful attention to correct diagnosis, early intervention and use of collagen dressing have improved outcome in these children.
儿童剥脱性皮肤病可以在许多方面模仿烧伤,需要早期诊断和治疗。在这里,我们列举了不同的皮肤状况与四个案例为基础的例子和他们的管理。临床表现:不同程度的皮肤受累,DRESS综合征受累严重,Stevens-Johnson综合征受累较轻。处理:这种剥脱性病变的处理是在我们治疗烧伤时将胶原膜应用于伤口。虽然全身性症状可导致死亡(例如,敷料),胶原蛋白敷料愈合伤口良好的上皮化。早期和适当的抗生素治疗是必须的。结论:注意正确诊断,早期干预和使用胶原蛋白敷料可改善患儿的预后。
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引用次数: 0
Oxidative stress in major thermal burns: Its implications and significance 重大热烧伤中的氧化应激:其含义和意义
Pub Date : 2018-01-01 DOI: 10.4103/ijb.ijb_37_17
R. Babu, M. Babu
Introduction: Thermal burns could prove dreadful to humankind. The morbidity and mortality is the interplay of intraneous and extraneous factors. Multidisciplinary approach plays a cardinal role in managing this catastrophe. This study is carried out to analyze the oxidative stress in thermal burns, its implications in management, and the significance it carries with it. Materials and Methods: This prospective study was carried out in 30 patients from January 2016 to December 2016. Quantitative analysis of oxidative stress and total antioxidant capacity was done on postburn day 3 and every 5 days thereafter. Results: The quantitative oxidative stress level was high, and antioxidant capacity was low in patients who had higher percentage total body surface area burn and predominant deep burn with temporal analysis. The patterns were strikingly different in patients who had mortality with patients who survived. Discussion: Thermal burn releases reactive oxygen species which causes profound changes in internal and external milieu. This alters the physiological response to treatment and impresses on the morbidity and mortality of the patient. Conclusion: Thereby, it could be construed that oxidative stress along with tailored intervention, timing of treatment, and recalcitrant attitude to treatment methodology has a significant role in determining the outcome of burn patients.
热烧伤对人类来说是可怕的。发病率和死亡率是内外因素的相互作用。多学科方法在管理这场灾难中起着重要作用。本研究旨在分析热烧伤中的氧化应激及其对管理的影响,以及它所带来的意义。材料与方法:本前瞻性研究于2016年1月至2016年12月在30例患者中进行。在燃烧后第3天及之后每5天定量分析氧化应激和总抗氧化能力。结果:时间分析显示,体表面积烧伤比例高、深度烧伤比例高的患者定量氧化应激水平高,抗氧化能力低。死亡患者和存活患者的模式明显不同。热烧伤释放活性氧,引起内外环境的深刻变化。这改变了对治疗的生理反应,并影响了患者的发病率和死亡率。结论:因此,氧化应激与针对性的干预、治疗时机和对治疗方法的顽固态度在决定烧伤患者的预后方面起着重要作用。
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引用次数: 8
Nanocrystalline silver gel versus conventional silver sulfadiazine cream as topical dressing for second-degree burn wound: A clinicopathological comparison 纳米晶银凝胶与传统磺胺嘧啶银乳膏作为二度烧伤创面外用敷料的临床病理比较
Pub Date : 2018-01-01 DOI: 10.4103/ijb.ijb_9_18
G. Dutta, Nandini Das, Abhishek Adhya, Kinkar Munian, B. Majumdar
Background: The use of topical chemotherapy is fundamental to prevent infections thereby reducing local inflammation, pain and early healing in superficial, and deep dermal burns. Among the whole gamut, choice of topical agents became an important decisive factor. Silver sulfadiazine (SSD) cream has been an important part of burns management for many years. The major complications attributed to silver compounds are due to the complex or anion sulfadiazine, not the silver itself. With better understanding of the physical and chemical properties, nanocrystalline silver particles have emerged as the most studied material for burn wound dressing recently. Having in mind the difficulties experienced, the aim of the present study is to compare SSD with nanosilver (nano-Ag) gel dressing to treat second-degree burn wounds. Materials and Methods: Over a period of 24 months, a total of 90 cases were studied. 45 patients randomly included in each group, further divided into two subgroups depending on depth (superficial and deep) and involvement of total body surface area (10%–20% and >20%–30%) to minimize bias. Clinical, microbiological, and histological parameters were analyzed. Results: In NS group, significantly less pain observed throughout the study period in both superficial and deep dermal burn patient. Pseudomonas was the predominant flora. Nano-Ag gel was effective in controlling most of the microorganisms except Klebsiella and Proteus sp. Healthy granulation tissue appeared faster (P = 0.0009) in deep dermal burns in nano-Ag group and confirmed histologically. Overall wound healing was more satisfactory in nano-Ag group for both superficial and deep dermal wounds, clinically as well as by histological examination. Conclusions: Clinical and histological studies showed that nano-Ag gel has a positive impact on overall healing process of the patients and proved more beneficial for the management of partial thickness burn as compared to SSD.
背景:使用局部化疗是预防感染的基础,从而减少局部炎症,疼痛和早期愈合浅表和深层皮肤烧伤。在整个范围内,外用药物的选择成为一个重要的决定性因素。磺胺嘧啶银乳膏多年来一直是烧伤治疗的重要组成部分。主要的并发症归因于银化合物是由于络合物或阴离子磺胺嘧啶,而不是银本身。随着人们对纳米晶银的物理和化学性质的深入了解,纳米晶银已成为近年来研究最多的烧伤创面敷料材料。考虑到所经历的困难,本研究的目的是比较SSD与纳米银(纳米银)凝胶敷料治疗二度烧伤创面。材料与方法:在24个月的时间里,共对90例患者进行研究。每组随机纳入45例患者,根据深度(浅表和深部)和累及全身表面积(10%-20%和> 20%-30%)进一步分为两个亚组,以尽量减少偏倚。分析临床、微生物学和组织学参数。结果:在整个研究期间,NS组在浅表和深部皮肤烧伤患者中观察到的疼痛明显减轻。假单胞菌是主要菌群。纳米银凝胶能有效控制除克雷伯菌和变形杆菌外的大部分微生物,纳米银组在皮肤深部烧伤中出现健康肉芽组织的速度更快(P = 0.0009),并在组织学上得到证实。纳米银组对皮肤浅层和深层创面的临床和组织学检查均较满意。结论:临床和组织学研究表明,纳米银凝胶对患者的整体愈合过程有积极的影响,与SSD相比,纳米银凝胶对部分厚度烧伤的治疗更有利。
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引用次数: 2
Can removal of epidermis delay rejection of cadaveric dermis-only allograft? A proof of concept study 切除表皮能否延缓尸体纯真皮同种异体移植物的排斥反应?概念验证研究
Pub Date : 2018-01-01 DOI: 10.4103/ijb.ijb_14_18
P. Agarwal, D. Sharma, A. Agarwal, L. Patel
Background: Skin allograft, used as a biological dressing, is usually rejected after 2 weeks. Epidermis contains immunogenic cells and its removal reduces antigenicity of allograft and delays its rejection. Materials and Methods: This proof of concept observational study was conducted in 50 patients of deep burns and posttraumatic wounds to evaluate the biological response of cadaveric glycerol-preserved dermis-only allograft. The epidermis was removed surgically, and the endpoints of healing or graft rejection were compared with historical controls of full-thickness allografts. Results: Dermis-only allograft take was seen in 82% patients at 20 days; in 34% patients at 4 weeks and in 16% patients at 8 weeks. Conclusion: Surgical removal of epidermis from cadaver allograft reduces its antigenicity and enables its longer survival.
背景:同种异体皮肤移植用作生物敷料,通常在2周后发生排斥反应。表皮含有免疫原性细胞,其去除可降低同种异体移植物的抗原性,延缓其排斥反应。材料和方法:在50例深度烧伤和创伤后伤口患者中进行了概念验证性观察研究,以评估尸体甘油保存的纯真皮同种异体移植物的生物学反应。手术切除表皮,并将愈合终点或移植物排斥反应与全层同种异体移植物的历史对照进行比较。结果:82%的患者在20天内出现纯真皮同种异体移植物;34%的患者在4周,16%的患者在8周。结论:手术切除尸体同种异体移植物表皮可降低其抗原性,延长其存活时间。
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引用次数: 2
Burns management in India: The way ahead 印度烧伤管理:未来之路
Pub Date : 2018-01-01 DOI: 10.4103/IJB.IJB_2_19
A. Singh
The problems of data collection in a country like ours are many: a. Multiplicity of treatment providers – Wide array of persons from plastic surgeons, surgeons, dermatologists, alternative medicine practitioners to Quacks are providing treatment to mild and moderate burns b. Absence of a robust health information system (HIS): Underdeveloped and developing countries often do not have the resources to invest in data collection and analysis.
在像我们这样的国家,数据收集的问题有很多:a.治疗提供者的多样性——从整形外科医生、外科医生、皮肤科医生、替代医学从业者到江湖郎中,各种各样的人都在为轻度和中度烧伤提供治疗。b.缺乏健全的卫生信息系统(HIS):不发达国家和发展中国家往往没有资源来投资于数据收集和分析。
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引用次数: 4
The impact of first-day levels of serum proteins and lipids and their subsequent trends as prognostic indicators of burn mortality 第一天血清蛋白和脂质水平及其随后趋势作为烧伤死亡率预后指标的影响
Pub Date : 2018-01-01 DOI: 10.4103/ijb.ijb_4_18
Shobhit Gupta, S. Bhattacharya, P. Goyal
Introduction: In severe burns, there is a profound systemic response that persists till the wounds heal. Since these physiological and metabolic derangements are dynamic over the clinical course of burns, it is expected that both trend of change and absolute values of the protein and lipid levels, to have a bearing on the prognosis and the ultimate outcome. Hence, this study was envisaged evaluate the prognostic value of these metabolic variables in burn patients. Materials and Methods: The study conducted on 100 adult patients of thermal burn (20% and 60% total body surface area). Serum albumin, globulin, total proteins, cholesterol and triglycerides (TGs) were estimated on alternate days starting from day till discharge or death. The 1st-day value and the trend of serial values throughout the clinical course were compared among nonsurvivors and survivors. Results: Mean serum values of albumin, globulin, and total protein on first-day of burns in survivor group were higher. Serum albumin levels of ≤2.1 g/dl at day one was a poor prognostic factor. The trend in the serum values of albumin, globulin, total protein, and cholesterol in survivor group was significantly positive and negative in nonsurvivors. Serum TGs, however, showed a nonsignificant negative trend in the survivors. Among the biochemical markers evaluated, most significant prognostic parameter was serum albumin, with maximum sensitivity and specificity. Conclusion: The cutoff values of proteins and trend of subsequent serial values can guide metabolic manipulations, albumin infusion, and dietary intake. In addition, these biochemical parameters merit inclusion in burn prognostic index scales.
在严重烧伤中,有一种深刻的全身反应持续到伤口愈合。由于这些生理和代谢紊乱在烧伤的临床过程中是动态的,因此预计蛋白质和脂质水平的变化趋势和绝对值都与预后和最终结果有关。因此,本研究旨在评估这些代谢变量在烧伤患者中的预后价值。材料与方法:对100例成人热烧伤患者(体表面积20%和60%)进行研究。血清白蛋白、球蛋白、总蛋白、胆固醇和甘油三酯(TGs)从第一天到出院或死亡每隔一天测定一次。比较非幸存者和幸存者的第1天值和整个临床过程中序列值的趋势。结果:存活组烧伤第1天血清白蛋白、球蛋白、总蛋白的平均值较高。第一天血清白蛋白水平≤2.1 g/dl是不良预后因素。血清白蛋白、球蛋白、总蛋白、胆固醇在存活组呈显著阳性,在非存活组呈显著阴性。然而,幸存者血清TGs呈不显著的阴性趋势。在评价的生化指标中,最重要的预后参数是血清白蛋白,具有最大的敏感性和特异性。结论:蛋白质截断值及后续序列值趋势可指导代谢操作、白蛋白输注及膳食摄入。此外,这些生化参数值得纳入烧伤预后指数量表。
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引用次数: 1
Correlation of burn injury and family history of burns among patients hospitalized at a public hospital in Nairobi, Kenya: A case–control study 肯尼亚内罗毕一家公立医院住院患者烧伤损伤与烧伤家族史的相关性:一项病例对照研究
Pub Date : 2018-01-01 DOI: 10.4103/ijb.ijb_8_18
J. Wanjeri, M. Kinoti, T. Olewe
Introduction: Burn injuries are physically and psychologically devastating types of trauma and are common among children especially in the home environment. They are more prevalent and are a public health problem in developing countries principally because of poor socioeconomic conditions. Effective prevention programs should be tailored for specific geographic locations and guided by the results of well-designed studies aimed at investigating local risk factors for burns. Studies targeting households can result in the identification of risk factors operating within family setups. Study Objective: To determine the association between occurrence of burn injury and family history of burns among patients hospitalized at a large hospital in a developing country in Africa. Methodology: This was age- and gender-matched case–control study comprising 202 patients admitted with burns (cases) and 202 nonsurgical patients (controls) admitted into the pediatric and medical wards. The study site was Kenyatta National Hospital, an 1800-bed national referral and teaching hospital in Kenya. The dependent variable was burn injury whereas the independent variables were family history of burn injury, history of hospitalization, and presence of a burn injury scar in the burnt family member. History of hospitalization following burn injury was termed as an indicator of severe burn injury having been sustained. Data Analytical Methods: The Chi-square test was used to identify the differences between the cases and control group variables, and logistic regression analysis and odds ratio were done to determine the relationship between the dependent and independent variables. Results: The male:female ratio was found to be 1:1, and burn injuries were found to be most common in the 0–4 years age bracket (n = 86, 42.6%), with the second most common age bracket being 20–40 years (n = 78, 38.6%). The injuries were mainly sustained in homes (n = 161, 80.9%) and the remainder at work (n = 15, 7.5%) and other places (n = 23, 11.6%). There was no significant difference between the two groups with regard to family history of burns (odds ratio [OR] = 0.689, 95% confidence interval [CI]: 0.443–1.073, P = 0.062) and presence of a burn scar in previously burnt family members (OR = 1.083, 95% CI: 0.308–3.805, P = 1.0). There was, however, a statistically significant higher incidence of postburn injury hospitalizations among the cases than the controls (OR = 2.354, 95% CI: 1.064–5.208, P = 0.033). Conclusion: Family history of burn injury with hospitalization of those affected is an indicator of households at a higher risk for burn injuries. More of the cases had history of hospitalization for burn injury among their family members, indicating that they had more risk factors operating within their environment, or their practices made them more prone to burn injuries. Identification of the specific risk factors involved is key in the prevention of burn injuries in homes.
引言:烧伤是身体和心理上毁灭性的创伤类型,在儿童中很常见,特别是在家庭环境中。它们在发展中国家更为普遍,是一个公共卫生问题,主要原因是社会经济条件差。有效的预防计划应该针对特定的地理位置,并以精心设计的研究结果为指导,旨在调查当地烧伤的危险因素。针对家庭的研究可以确定在家庭环境中起作用的风险因素。研究目的:了解非洲某发展中国家某大型医院住院患者烧伤发生与烧伤家族史的关系。方法:这是一项年龄和性别匹配的病例对照研究,包括202例住院的烧伤患者(病例)和202例住院的儿科和内科病房的非手术患者(对照组)。研究地点是肯尼亚肯雅塔国家医院,这是一家拥有1800张床位的国家转诊和教学医院。因变量为烧伤,自变量为烧伤家族史、住院史和烧伤家庭成员是否有烧伤疤痕。烧伤后住院史被认为是严重烧伤的一个指标。数据分析方法:病例与对照组变量间差异采用卡方检验,因变量与自变量间关系采用logistic回归分析和比值比分析。结果:男女比例为1:1,0 ~ 4岁年龄组烧伤发生率最高(n = 86, 42.6%), 20 ~ 40岁年龄组次之(n = 78, 38.6%)。主要发生在家中(n = 161, 80.9%),其余发生在工作场所(n = 15, 7.5%)和其他场所(n = 23, 11.6%)。两组患者在烧伤家族史(优势比[OR] = 0.689, 95%可信区间[CI]: 0.443-1.073, P = 0.062)和既往烧伤家庭成员存在烧伤疤痕(OR = 1.083, 95% CI: 0.308-3.805, P = 1.0)方面无显著差异。然而,病例中烧伤后住院的发生率高于对照组(OR = 2.354, 95% CI: 1.064-5.208, P = 0.033)。结论:住院患者有烧伤家族史是家庭发生烧伤风险较高的一个指标。更多病例的家庭成员有烧伤住院史,这表明他们的环境中有更多的危险因素,或者他们的做法使他们更容易发生烧伤。确定所涉及的具体风险因素是预防家庭烧伤的关键。
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引用次数: 2
Prevention of microstomia in patients having perioral burns 口腔周围烧伤患者小口畸形的预防
Pub Date : 2018-01-01 DOI: 10.4103/0971-653X.206702
V. Puri, R. Shrotriya, Nikhil Ghubade, S. Kumail, S. Mayekar, Deepak Patil
Facial burns are a common cause of morbidity in burn patients. Deep burns over lip and oral commissures heal with scarring resulting in microstomia which leads to eating difficulties, hygiene problems, and facial disfigurement frequently requiring surgical correction. Hence, the prevention of microstomia becomes an important part of management of perioral burns. Here, the authors discuss their experience in the prevention of microstomia in burn patients with perioral involvement.
面部烧伤是烧伤患者发病的常见原因。嘴唇和口腔交界处的深度烧伤愈合后留下疤痕,导致小口畸形,导致饮食困难,卫生问题和面部畸形,经常需要手术矫正。因此,预防小口形成成为口腔周围烧伤治疗的重要组成部分。在这里,作者讨论他们的经验,预防小口在烧伤患者的口腔周围受损伤。
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引用次数: 1
期刊
Indian journal of burns
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