Pub Date : 2024-07-10DOI: 10.5005/jp-journals-11007-0109
Govindaraj Vishnukanth, Sivaselvi Chellamuthu, Mahesh B Vemuri, Nachiappa G Rajesh
Giant cell tumors (GCT) of bone also referred to as osteoclastoma or myeloid sarcoma are usually benign tumors but have the potential for local recurrence and metastasis. Giant cell tumors mostly involves the long bones with the proximal tibia and distal femur sites. Giant cell tumors of the spine presenting above the level of the sacrum is relatively less common. We report a patient with GCT arising from dorsal vertebrae and presenting as a huge mediastinal mass. A 25-year-old female presented with bilateral lower limb weakness, breathlessness, and difficulty in speaking. Chest X-ray showed bilateral upper lobe mass. On further evaluation with contrast-enhanced computed tomography (CECT) of the thorax a large well defined heterogeneously enhancing posterior mediastinal lesion with necrotic areas within and bony infiltration was noted. Sequential chest X-ray was suggestive of rapid progression within 15 days. Ultrasound-guided biopsy of mass lesion revealed features of giant cell tumor with immunohistochemical markers strongly positive for CD68, negative for S100, and β -HCG. The patient was subsequently started on denosumab given unresectable pulmonary metastasis.
骨巨细胞瘤（GCT）又称破骨细胞瘤或骨髓肉瘤，通常是良性肿瘤，但有局部复发和转移的可能。巨细胞瘤主要累及胫骨近端和股骨远端的长骨。脊柱巨细胞瘤出现在骶骨水平以上的部位相对较少。我们报告了一名背椎巨细胞瘤患者，其表现为纵隔巨大肿块。一名 25 岁的女性患者出现双下肢无力、呼吸困难和说话困难。胸部 X 光片显示双侧上叶肿块。在使用对比增强计算机断层扫描（CECT）对胸部进行进一步评估时，发现一个界限清晰、异质性增强的巨大后纵隔病变，内部有坏死区和骨质浸润。连续胸部 X 光片显示，病变在 15 天内迅速发展。超声引导下的肿块活检显示出巨细胞瘤的特征，免疫组化标记物 CD68 强阳性，S100 和 β -HCG 阴性。由于肺转移无法切除，患者随后开始使用地诺单抗。
{"title":"Giant-cell Tumor of Dorsal Vertebra Presenting as a Posterior Mediastinal Mass: A Rare Case Report","authors":"Govindaraj Vishnukanth, Sivaselvi Chellamuthu, Mahesh B Vemuri, Nachiappa G Rajesh","doi":"10.5005/jp-journals-11007-0109","DOIUrl":"https://doi.org/10.5005/jp-journals-11007-0109","url":null,"abstract":"Giant cell tumors (GCT) of bone also referred to as osteoclastoma or myeloid sarcoma are usually benign tumors but have the potential for local recurrence and metastasis. Giant cell tumors mostly involves the long bones with the proximal tibia and distal femur sites. Giant cell tumors of the spine presenting above the level of the sacrum is relatively less common. We report a patient with GCT arising from dorsal vertebrae and presenting as a huge mediastinal mass. A 25-year-old female presented with bilateral lower limb weakness, breathlessness, and difficulty in speaking. Chest X-ray showed bilateral upper lobe mass. On further evaluation with contrast-enhanced computed tomography (CECT) of the thorax a large well defined heterogeneously enhancing posterior mediastinal lesion with necrotic areas within and bony infiltration was noted. Sequential chest X-ray was suggestive of rapid progression within 15 days. Ultrasound-guided biopsy of mass lesion revealed features of giant cell tumor with immunohistochemical markers strongly positive for CD68, negative for S100, and β -HCG. The patient was subsequently started on denosumab given unresectable pulmonary metastasis.","PeriodicalId":133412,"journal":{"name":"The Indian Journal of Chest Diseases and Allied Sciences","volume":"103 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141835663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-10DOI: 10.5005/jp-journals-11007-0112
M. Walia, Ruchika Bhagat
{"title":"Case of Cardio-vocal Syndrome with Dysphagia Aortica: A Rare Entity","authors":"M. Walia, Ruchika Bhagat","doi":"10.5005/jp-journals-11007-0112","DOIUrl":"https://doi.org/10.5005/jp-journals-11007-0112","url":null,"abstract":"","PeriodicalId":133412,"journal":{"name":"The Indian Journal of Chest Diseases and Allied Sciences","volume":"49 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141835369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-10DOI: 10.5005/jp-journals-11007-0117
Anand Jaiswal, B. Datta, Ashish Kumar Prakash, Roopanshi Jain
{"title":"Self Expectoration of a Forgotten Foreign Body","authors":"Anand Jaiswal, B. Datta, Ashish Kumar Prakash, Roopanshi Jain","doi":"10.5005/jp-journals-11007-0117","DOIUrl":"https://doi.org/10.5005/jp-journals-11007-0117","url":null,"abstract":"","PeriodicalId":133412,"journal":{"name":"The Indian Journal of Chest Diseases and Allied Sciences","volume":"52 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141835421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A 41-year-old female patient presented with a painful swelling in right breast for 6 months. Pus was aspirated and subjected to cartridge-based nucleic acid amplification test (CBNAAT) and line probe assay (LPA) which confirmed it as a case of multidrug-resistant tuberculosis. Isolates were resistant to rifampicin (R) and second-line injectables (SLI). The patient improved on bedaquiline (BDQ)-containing regimen.
{"title":"Primary Multidrug-resistant Tuberculosis of the Breast: A Rare Entity","authors":"Shubhra Jain, Vinod Joshi, Aditya Aggarwal, Jaanakhi Velayutham Muthu","doi":"10.5005/jp-journals-11007-0110","DOIUrl":"https://doi.org/10.5005/jp-journals-11007-0110","url":null,"abstract":"A 41-year-old female patient presented with a painful swelling in right breast for 6 months. Pus was aspirated and subjected to cartridge-based nucleic acid amplification test (CBNAAT) and line probe assay (LPA) which confirmed it as a case of multidrug-resistant tuberculosis. Isolates were resistant to rifampicin (R) and second-line injectables (SLI). The patient improved on bedaquiline (BDQ)-containing regimen.","PeriodicalId":133412,"journal":{"name":"The Indian Journal of Chest Diseases and Allied Sciences","volume":"35 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141835262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-10DOI: 10.5005/jp-journals-11007-0113
Mayank Mishra, G. Sindhwani, Saikat Banerjee, Vickey Panjiyar, Prakhar Sharma, Ganesh Sanjan, Y. Bahurupi, Narayan Joshi, R. Dua, LokeshKumar Saini
{"title":"Test-retest Repeatability and Minimal Detectable Change of 1-minute Sit-to-Stand Test for the Ability to Detect Exercise-induced Oxygen Desaturation in Patients with Interstitial Lung Diseases","authors":"Mayank Mishra, G. Sindhwani, Saikat Banerjee, Vickey Panjiyar, Prakhar Sharma, Ganesh Sanjan, Y. Bahurupi, Narayan Joshi, R. Dua, LokeshKumar Saini","doi":"10.5005/jp-journals-11007-0113","DOIUrl":"https://doi.org/10.5005/jp-journals-11007-0113","url":null,"abstract":"","PeriodicalId":133412,"journal":{"name":"The Indian Journal of Chest Diseases and Allied Sciences","volume":"80 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141835547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Physicians' Perspectives and Practice Patterns in India on the Diagnosis and Treatment of Interstitial Lung Disease (IN-ILD Survey)","authors":"Prashant Chhajed, Jaideep Gogtay, Sujeet K Rajan, Sushant Meshram, Monali Mehta, Meena Lopez","doi":"10.5005/jp-journals-11007-0116","DOIUrl":"https://doi.org/10.5005/jp-journals-11007-0116","url":null,"abstract":"","PeriodicalId":133412,"journal":{"name":"The Indian Journal of Chest Diseases and Allied Sciences","volume":"106 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141835539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-10DOI: 10.5005/jp-journals-11007-0115
Rohit Kumar, P. Ish, Nitesh Gupta, Sanchit Mohan
Superior vena cava syndrome (SVCS) can be associated with benign as well as malignant causes, NSCLC being the most common malignant cause and is rarely associated with adenocarcinoma of the lung. Symptoms may range from dyspnea to respiratory failure requiring urgent intervention. Endovascular stenting, radiotherapy, and treatment of underlying cancer are required to relieve symptoms. Balloon dilatation of SVC is usually done for SVC secondary to benign disease. We report a case of adenocarcinoma of the lung presenting with SVCS, which responded well to SVC dilatation and chemotherapy.
{"title":"Superior Vena Cava Syndrome in Pulmonary Adenocarcinoma: A Rare Clinical Presentation and a Different Course of Management","authors":"Rohit Kumar, P. Ish, Nitesh Gupta, Sanchit Mohan","doi":"10.5005/jp-journals-11007-0115","DOIUrl":"https://doi.org/10.5005/jp-journals-11007-0115","url":null,"abstract":"Superior vena cava syndrome (SVCS) can be associated with benign as well as malignant causes, NSCLC being the most common malignant cause and is rarely associated with adenocarcinoma of the lung. Symptoms may range from dyspnea to respiratory failure requiring urgent intervention. Endovascular stenting, radiotherapy, and treatment of underlying cancer are required to relieve symptoms. Balloon dilatation of SVC is usually done for SVC secondary to benign disease. We report a case of adenocarcinoma of the lung presenting with SVCS, which responded well to SVC dilatation and chemotherapy.","PeriodicalId":133412,"journal":{"name":"The Indian Journal of Chest Diseases and Allied Sciences","volume":"38 s169","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141835310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-10DOI: 10.5005/jp-journals-11007-0111
Raghu Srikanti, B. R. Dollu, Uthara Natarajan, Kalaivani Shanmuganandavadivel, Siddavali Chagalamarri, Harika Atmuri, Sudheer Diyya, Tanuja Sri Vushakoyala, D. N. Avanigadda
Background: Obesity is an important risk factor for the development of obstructive sleep apnea (OSA). Although clinical and epidemiological studies have shown that OSA and obesity are strongly associated, few studies have examined the associations between anthropometric obesity indices and OSA, especially in the South Indian population. This study aimed to evaluate the influence of anthropometric obesity indices on OSA in an Indian population. Materials and Methods: Anthropometric indices, such as neck circumference (NC), waist circumference (WC), and body mass index (BMI), were assessed in 50 subjects with suspected OSA. Results: Of the 50 subjects assessed, 39 (78%) were diagnosed with OSA, and 11 (22%) had no OSA. Of these, 37 (74%) were males and 13 (26%) were females. Patients with OSA had a significantly higher age, BMI, WC, and NC than patients without OSA. The mean cut-off values of NC, WC, and BMI in males were 39, 93.8, and 29.8 respectively. The mean cut-off values of NC, WC, and BMI in females were 39.3, 96.5, and 30 respectively. Conclusion: Increased anthropometric indices were significantly associated with the presence and severity of OSA in the Indian population. This study also demonstrated the mean cut-off values for increased OSA risk for body mass index, waist circumference, and neck circumference. When the means of different variables are compared with three degrees of severity of OSA it was observed that BMI and NC had a significant difference while WC had no significant difference based on severity.
背景：肥胖是导致阻塞性睡眠呼吸暂停（OSA）的重要风险因素。尽管临床和流行病学研究表明 OSA 与肥胖密切相关，但很少有研究探讨人体测量肥胖指数与 OSA 之间的关系，尤其是在南印度人群中。本研究旨在评估印度人群中人体测量肥胖指数对 OSA 的影响。材料和方法：对 50 名疑似 OSA 患者的颈围 (NC)、腰围 (WC) 和体重指数 (BMI) 等人体测量指标进行评估。结果：在接受评估的 50 名受试者中，39 人（78%）被确诊为 OSA，11 人（22%）没有 OSA。其中，37 人（74%）为男性，13 人（26%）为女性。OSA 患者的年龄、体重指数（BMI）、腹围和 NC 均明显高于非 OSA 患者。男性的 NC、WC 和 BMI 的平均临界值分别为 39、93.8 和 29.8。女性的 NC、WC 和 BMI 的平均临界值分别为 39.3、96.5 和 30。结论在印度人群中，人体测量指数的增加与 OSA 的存在和严重程度有明显关联。这项研究还显示了体重指数、腰围和颈围增加 OSA 风险的平均临界值。将不同变量的平均值与 OSA 的三种严重程度进行比较后发现，体重指数和 NC 有显著差异，而腰围则因严重程度不同而无显著差异。
{"title":"Association between Anthropometric Indices and OSA: A Hospital-based Study","authors":"Raghu Srikanti, B. R. Dollu, Uthara Natarajan, Kalaivani Shanmuganandavadivel, Siddavali Chagalamarri, Harika Atmuri, Sudheer Diyya, Tanuja Sri Vushakoyala, D. N. Avanigadda","doi":"10.5005/jp-journals-11007-0111","DOIUrl":"https://doi.org/10.5005/jp-journals-11007-0111","url":null,"abstract":"Background: Obesity is an important risk factor for the development of obstructive sleep apnea (OSA). Although clinical and epidemiological studies have shown that OSA and obesity are strongly associated, few studies have examined the associations between anthropometric obesity indices and OSA, especially in the South Indian population. This study aimed to evaluate the influence of anthropometric obesity indices on OSA in an Indian population. Materials and Methods: Anthropometric indices, such as neck circumference (NC), waist circumference (WC), and body mass index (BMI), were assessed in 50 subjects with suspected OSA. Results: Of the 50 subjects assessed, 39 (78%) were diagnosed with OSA, and 11 (22%) had no OSA. Of these, 37 (74%) were males and 13 (26%) were females. Patients with OSA had a significantly higher age, BMI, WC, and NC than patients without OSA. The mean cut-off values of NC, WC, and BMI in males were 39, 93.8, and 29.8 respectively. The mean cut-off values of NC, WC, and BMI in females were 39.3, 96.5, and 30 respectively. Conclusion: Increased anthropometric indices were significantly associated with the presence and severity of OSA in the Indian population. This study also demonstrated the mean cut-off values for increased OSA risk for body mass index, waist circumference, and neck circumference. When the means of different variables are compared with three degrees of severity of OSA it was observed that BMI and NC had a significant difference while WC had no significant difference based on severity.","PeriodicalId":133412,"journal":{"name":"The Indian Journal of Chest Diseases and Allied Sciences","volume":"12 s14","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141835466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-03DOI: 10.5005/jp-journals-11007-0105
Akash Sengupta, Saikat Dutta
{"title":"A Little More Than Just Air and Fluid: An Uncommon Case of Hydropneumothorax","authors":"Akash Sengupta, Saikat Dutta","doi":"10.5005/jp-journals-11007-0105","DOIUrl":"https://doi.org/10.5005/jp-journals-11007-0105","url":null,"abstract":"","PeriodicalId":133412,"journal":{"name":"The Indian Journal of Chest Diseases and Allied Sciences","volume":"150 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140746730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：