Pub Date : 2022-02-04DOI: 10.5005/jp-journals-10088-11165
S. Mayilvaganan, S. Idrees
{"title":"Comment on “Effectiveness and Safety of Thermal Ablation in the Treatment of Primary Hyperparathyroidism: A Multicenter Study” Published in JCEM","authors":"S. Mayilvaganan, S. Idrees","doi":"10.5005/jp-journals-10088-11165","DOIUrl":"https://doi.org/10.5005/jp-journals-10088-11165","url":null,"abstract":"","PeriodicalId":135260,"journal":{"name":"Indian Journal of Endocrine Surgery and Research","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128438295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Message from Editor in Chief's Desk","authors":"P. Ramakant","doi":"10.5005/ijesr-16-2-iv","DOIUrl":"https://doi.org/10.5005/ijesr-16-2-iv","url":null,"abstract":"","PeriodicalId":135260,"journal":{"name":"Indian Journal of Endocrine Surgery and Research","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116644883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-02-04DOI: 10.5005/jp-journals-10088-11174
M. Pradhan, A. Bhatnagar, R. Saxena, S. Mayilvaganan, S. Pande, V. Upadhyaya, P. Yadav, R. Rahul, Asish Singh, P. Verma
{"title":"Impact of COVID-19 Pandemic Forced Lockdown on Non-COVID Super-specialty Surgical Case Management in India","authors":"M. Pradhan, A. Bhatnagar, R. Saxena, S. Mayilvaganan, S. Pande, V. Upadhyaya, P. Yadav, R. Rahul, Asish Singh, P. Verma","doi":"10.5005/jp-journals-10088-11174","DOIUrl":"https://doi.org/10.5005/jp-journals-10088-11174","url":null,"abstract":"","PeriodicalId":135260,"journal":{"name":"Indian Journal of Endocrine Surgery and Research","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116468904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-02-04DOI: 10.5005/jp-journals-10088-11173
Rizhin Sooraj, G. Bhat, N. Raja, Upander Kumar, Kulranjan Singh, P. Ramakant, Anshuman Mishra
A bstrAct A 35-year-old woman presented with episodic abdominal pain associated with palpitation and frontal headache. Physical examination revealed thyroid nodule along with itchy scapular cutaneous lesions suspicious of cutaneous lichen amyloidosis (CLA). Biochemical and imaging workup showed bilateral adrenal lesions with positive 24-hour urinary metanephrine/normetanephrine levels and fine needle aspiration cytology (FNAC) of the thyroid nodule confirmed medullary thyroid carcinoma (MTC) of the thyroid. Bilateral pheochromocytoma with MTC and CLA prompted us for targeted genetic testing for codon 634 in rearranged during transfection (RET) gene which confirmed the diagnosis of multiple endocrine neoplasia type IIA (MEN IIA) CLA variant. The patient underwent bilateral cortical-sparing open adrenalectomy followed by total thyroidectomy with central compartment neck dissection and bilateral modified radical neck dissection. Of her four asymptomatic children, two were found to harbor the mutation and are being managed appropriately. High index of suspicion with detailed history and thorough clinical examination can help us perform targeted genetic testing and appropriate management in resource-constrained settings.
{"title":"Multiple Endocrine Neoplasia Type IIA with Cutaneous Lichen Amyloidosis","authors":"Rizhin Sooraj, G. Bhat, N. Raja, Upander Kumar, Kulranjan Singh, P. Ramakant, Anshuman Mishra","doi":"10.5005/jp-journals-10088-11173","DOIUrl":"https://doi.org/10.5005/jp-journals-10088-11173","url":null,"abstract":"A bstrAct A 35-year-old woman presented with episodic abdominal pain associated with palpitation and frontal headache. Physical examination revealed thyroid nodule along with itchy scapular cutaneous lesions suspicious of cutaneous lichen amyloidosis (CLA). Biochemical and imaging workup showed bilateral adrenal lesions with positive 24-hour urinary metanephrine/normetanephrine levels and fine needle aspiration cytology (FNAC) of the thyroid nodule confirmed medullary thyroid carcinoma (MTC) of the thyroid. Bilateral pheochromocytoma with MTC and CLA prompted us for targeted genetic testing for codon 634 in rearranged during transfection (RET) gene which confirmed the diagnosis of multiple endocrine neoplasia type IIA (MEN IIA) CLA variant. The patient underwent bilateral cortical-sparing open adrenalectomy followed by total thyroidectomy with central compartment neck dissection and bilateral modified radical neck dissection. Of her four asymptomatic children, two were found to harbor the mutation and are being managed appropriately. High index of suspicion with detailed history and thorough clinical examination can help us perform targeted genetic testing and appropriate management in resource-constrained settings.","PeriodicalId":135260,"journal":{"name":"Indian Journal of Endocrine Surgery and Research","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116985189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-02-04DOI: 10.5005/jp-journals-10088-11176
Mayank Bhasin, A. Arora
Aim: This systematic review aimed to analyze efficacy of axillary ultrasonography (USG) in differentiating normal from abnormal lymph nodes (LNs) in breast cancer patients, taking into account the different criteria used. Background: Identification of pretreatment axillary LN metastasis is one of the most important prognostic factors in breast cancer, and it affects the surgical plan and oncological management after surgery. Review results: A PubMed search was made using the following items: “Ultrasonography” [Mesh] AND “Axilla” [Mesh] AND “Breast Neoplasms” [Mesh]. A total of 34 studies were included in the review analysis. Studies were divided according to the LN feature studied into six subheadings which include size, cortex thickness, hilum changes, long axis-to-short axis ratio (L/S ratio), combination of multiple morphological factors, and combination of both morphology and size. For LN size, sensitivity and specificity ranged from 49 to 95%, 34 to 97.4%; cortical thickness 35 to 96%, 36 to 92%; hilar changes 24 to 92%, 23 to 100%; L/S ratio 65 to 100%, 18 to 65%; morphological features 26 to 94%, 76 to 100%; and combination of both morphological and size 18 to 100%, 50 to 100%, respectively. Conclusion: Role of USG in pretreatment axillary staging has been extensively studied. Various diagnostic criteria have been used for defining abnormal LN, which leads to difficult comparisons between various studies. Clinical significance: Pretreatment evaluation of axilla with USG, using multiple criteria, like LN size, L/S ratio, cortical, and hilar abnormalities in combination with morphological features, gave the best accuracy for detection of abnormal nodes and lowest false-negative rates in breast cancer patients.
{"title":"Role of Ultrasound in Pretreatment Evaluation of Lymph Node Status in Carcinoma Breast: A Systematic Review","authors":"Mayank Bhasin, A. Arora","doi":"10.5005/jp-journals-10088-11176","DOIUrl":"https://doi.org/10.5005/jp-journals-10088-11176","url":null,"abstract":"Aim: This systematic review aimed to analyze efficacy of axillary ultrasonography (USG) in differentiating normal from abnormal lymph nodes (LNs) in breast cancer patients, taking into account the different criteria used. Background: Identification of pretreatment axillary LN metastasis is one of the most important prognostic factors in breast cancer, and it affects the surgical plan and oncological management after surgery. Review results: A PubMed search was made using the following items: “Ultrasonography” [Mesh] AND “Axilla” [Mesh] AND “Breast Neoplasms” [Mesh]. A total of 34 studies were included in the review analysis. Studies were divided according to the LN feature studied into six subheadings which include size, cortex thickness, hilum changes, long axis-to-short axis ratio (L/S ratio), combination of multiple morphological factors, and combination of both morphology and size. For LN size, sensitivity and specificity ranged from 49 to 95%, 34 to 97.4%; cortical thickness 35 to 96%, 36 to 92%; hilar changes 24 to 92%, 23 to 100%; L/S ratio 65 to 100%, 18 to 65%; morphological features 26 to 94%, 76 to 100%; and combination of both morphological and size 18 to 100%, 50 to 100%, respectively. Conclusion: Role of USG in pretreatment axillary staging has been extensively studied. Various diagnostic criteria have been used for defining abnormal LN, which leads to difficult comparisons between various studies. Clinical significance: Pretreatment evaluation of axilla with USG, using multiple criteria, like LN size, L/S ratio, cortical, and hilar abnormalities in combination with morphological features, gave the best accuracy for detection of abnormal nodes and lowest false-negative rates in breast cancer patients.","PeriodicalId":135260,"journal":{"name":"Indian Journal of Endocrine Surgery and Research","volume":"90 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132845395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-02-04DOI: 10.5005/jp-journals-10088-11172
K. C. Mohapatra, S. Ethiraj, G. Panda, Ramapada Mohapatra
In the last few decades, there has been remarkable progress in the diagnosis as well as treatment of primary hyperparathyroidism (PHPT) worldwide due to the advent of automated serum calcium estimation and radioimmunoassay of parathormone. Consequently, a fairly good number of asymptomatic and incidentally detected cases of PHPT who could have been missed otherwise are now being evaluated and treated successfully. Although this turn around is more pronounced in the West, the scenario has not appreciably changed in India. Lack of awareness and clinical suspicion among the clinicians and negligible use of biochemical screening tests are the common factors responsible for the diagnostic delay as is evident in our case report. Such delay in diagnosis and institution of treatment results in overtly symptomatic disease with affection of several target organs. We report the diagnostic dilemma and delay in treatment in one of our cases; a 28-year-old female who despite having severe PHPT at the time of diagnosis could be managed successfully with parathyroidectomy.
{"title":"Diagnostic Issues of Primary Hyperparathyroidism in Indian Patients: The Perspectives and Imperatives—A Case Report","authors":"K. C. Mohapatra, S. Ethiraj, G. Panda, Ramapada Mohapatra","doi":"10.5005/jp-journals-10088-11172","DOIUrl":"https://doi.org/10.5005/jp-journals-10088-11172","url":null,"abstract":"In the last few decades, there has been remarkable progress in the diagnosis as well as treatment of primary hyperparathyroidism (PHPT) worldwide due to the advent of automated serum calcium estimation and radioimmunoassay of parathormone. Consequently, a fairly good number of asymptomatic and incidentally detected cases of PHPT who could have been missed otherwise are now being evaluated and treated successfully. Although this turn around is more pronounced in the West, the scenario has not appreciably changed in India. Lack of awareness and clinical suspicion among the clinicians and negligible use of biochemical screening tests are the common factors responsible for the diagnostic delay as is evident in our case report. Such delay in diagnosis and institution of treatment results in overtly symptomatic disease with affection of several target organs. We report the diagnostic dilemma and delay in treatment in one of our cases; a 28-year-old female who despite having severe PHPT at the time of diagnosis could be managed successfully with parathyroidectomy.","PeriodicalId":135260,"journal":{"name":"Indian Journal of Endocrine Surgery and Research","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117298233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-08-26DOI: 10.5005/jp-journals-10088-11157
Sarada Khadka
The follicular thyroid carcinoma (FTC) may present with synchronous metastases. Rarely, the metastatic lesion is the only finding at the time of presentation (as in our case) leading to a diagnostic dilemma. We report an occult metastatic FTC case of a 68-year-old man who underwent excision of a rib tumor 10 years back. The histopathology confirmed the metastatic thyroid carcinoma but clinicoradiological evaluation did not reveal any thyroid nodule. He did not undergo a total thyroidectomy at that time. Now, he presented with pulsatile scalp swelling for 6 months. On examination, he was found to have a solitary thyroid nodule also. Fine needle aspiration cytology from scalp swelling and thyroid nodule demonstrated thyroid cells and follicular neoplasm, respectively, establishing the diagnosis of metastatic follicular thyroid cancer. The radioactive iodine (RAI) is given after total thyroidectomy. Total thyroidectomy followed by RAI is indicated even in cases of occult metastatic follicular thyroid carcinoma.
{"title":"An Occult Follicular Thyroid Carcinoma Discovered 10 Years after the Metastasis","authors":"Sarada Khadka","doi":"10.5005/jp-journals-10088-11157","DOIUrl":"https://doi.org/10.5005/jp-journals-10088-11157","url":null,"abstract":"The follicular thyroid carcinoma (FTC) may present with synchronous metastases. Rarely, the metastatic lesion is the only finding at the time of presentation (as in our case) leading to a diagnostic dilemma. We report an occult metastatic FTC case of a 68-year-old man who underwent excision of a rib tumor 10 years back. The histopathology confirmed the metastatic thyroid carcinoma but clinicoradiological evaluation did not reveal any thyroid nodule. He did not undergo a total thyroidectomy at that time. Now, he presented with pulsatile scalp swelling for 6 months. On examination, he was found to have a solitary thyroid nodule also. Fine needle aspiration cytology from scalp swelling and thyroid nodule demonstrated thyroid cells and follicular neoplasm, respectively, establishing the diagnosis of metastatic follicular thyroid cancer. The radioactive iodine (RAI) is given after total thyroidectomy. Total thyroidectomy followed by RAI is indicated even in cases of occult metastatic follicular thyroid carcinoma.","PeriodicalId":135260,"journal":{"name":"Indian Journal of Endocrine Surgery and Research","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129609620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-08-26DOI: 10.5005/JP-JOURNALS-10088-11162
Surabhi Garg, L. Enny, Upander Kumar, N. Raja, P. Ramakant, Kulranjan Singh, Anshuman Mishra
{"title":"Succinate Dehydrogenase Mutation and Paraganglioma Syndromes: A Review Article","authors":"Surabhi Garg, L. Enny, Upander Kumar, N. Raja, P. Ramakant, Kulranjan Singh, Anshuman Mishra","doi":"10.5005/JP-JOURNALS-10088-11162","DOIUrl":"https://doi.org/10.5005/JP-JOURNALS-10088-11162","url":null,"abstract":"","PeriodicalId":135260,"journal":{"name":"Indian Journal of Endocrine Surgery and Research","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124159515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"From Desk of Honorary Secretary IAES","authors":"Dr. S. Mayilvaganan","doi":"10.5005/ijesr-16-2-viii","DOIUrl":"https://doi.org/10.5005/ijesr-16-2-viii","url":null,"abstract":"","PeriodicalId":135260,"journal":{"name":"Indian Journal of Endocrine Surgery and Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115504733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-08-26DOI: 10.5005/jp-journals-10088-11152
V. Thomas, A. Cherian, P. Jacob
A bstrAct Collagenous fibroma, earlier known as desmoplastic fibroblastoma, is a rare fibrous soft tissue tumor that has been described more often in the extremities, where it presents as a slow-growing and painless mass. We report a case of a 48-year-old gentleman, who presented with an anterior neck swelling with substernal extension, resembling a retrosternal goiter, after clinical examination and radiological and cytological assessments. Intraoperatively, we found it to be a mass abutting but separate from the thyroid, arising from the deep aspect of sternum inaccessible from the neck requiring partial-sternotomy for excision. Histopathological examination revealed a hypocellular tumor made of spindle to stellate cells with surrounding stroma showing collagenization with collagen bundles to myxoid changes. This report documents a rare differential for goiter, only the second case reported in the central neck.
{"title":"Collagenous Fibroma Mimicking a Retrosternal Goiter: A Case Report","authors":"V. Thomas, A. Cherian, P. Jacob","doi":"10.5005/jp-journals-10088-11152","DOIUrl":"https://doi.org/10.5005/jp-journals-10088-11152","url":null,"abstract":"A bstrAct Collagenous fibroma, earlier known as desmoplastic fibroblastoma, is a rare fibrous soft tissue tumor that has been described more often in the extremities, where it presents as a slow-growing and painless mass. We report a case of a 48-year-old gentleman, who presented with an anterior neck swelling with substernal extension, resembling a retrosternal goiter, after clinical examination and radiological and cytological assessments. Intraoperatively, we found it to be a mass abutting but separate from the thyroid, arising from the deep aspect of sternum inaccessible from the neck requiring partial-sternotomy for excision. Histopathological examination revealed a hypocellular tumor made of spindle to stellate cells with surrounding stroma showing collagenization with collagen bundles to myxoid changes. This report documents a rare differential for goiter, only the second case reported in the central neck.","PeriodicalId":135260,"journal":{"name":"Indian Journal of Endocrine Surgery and Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128401356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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