Pub Date : 2024-09-25DOI: 10.1016/j.ijcard.2024.132600
{"title":"Circular RNAs interplay with Coronary Microvascular Dysfunction: A prognostic key for patients with coronary artery disease?","authors":"","doi":"10.1016/j.ijcard.2024.132600","DOIUrl":"10.1016/j.ijcard.2024.132600","url":null,"abstract":"","PeriodicalId":13710,"journal":{"name":"International journal of cardiology","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142326704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-24DOI: 10.1016/j.ijcard.2024.132574
{"title":"In memoriam: Antonio L'Abbate","authors":"","doi":"10.1016/j.ijcard.2024.132574","DOIUrl":"10.1016/j.ijcard.2024.132574","url":null,"abstract":"","PeriodicalId":13710,"journal":{"name":"International journal of cardiology","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0167527324011963/pdfft?md5=321218e49ef18e449223a3fd60a0a3df&pid=1-s2.0-S0167527324011963-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142315721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-24DOI: 10.1016/j.ijcard.2024.132592
{"title":"Sudden cardiac death risk prediction in Fabry disease: How many strings do we have on our bow?","authors":"","doi":"10.1016/j.ijcard.2024.132592","DOIUrl":"10.1016/j.ijcard.2024.132592","url":null,"abstract":"","PeriodicalId":13710,"journal":{"name":"International journal of cardiology","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142326705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-21DOI: 10.1016/j.ijcard.2024.132582
Background
Pregnancy-Associated Spontaneous Coronary Artery Dissection (P-SCAD) is the most common cause of myocardial infarction in pregnancy and postpartum. Aim of this systematic review is to provide a descriptive picture of P-SCAD presentation, clinical course, management and outcomes.
Methods
International databases were systematically screened up to November 2023 and all published P-SCAD case reports/series identified; additionally, we gathered four original cases, establishing a new database for the derived cohort.
Results
253 studies (215 case reports, 38 case series) were included for the analysis, enrolling 316 patients admitted between 1952 and 2023. Median age was 34 (SD 5) years old, 64 (20.4 %) were prepartum, 249 (79.6 %) postpartum. Most common presentation was ST-elevation myocardial infarction (72.6 %). Cardiac arrest and cardiogenic shock occurred in 18.4 % and 16.1 %, respectively. Multivessel dissection was present in 45.2 % of cases, with left anterior descending artery being most frequently affected (74.4 %). Initial therapeutic strategy was medical therapy in 54.8 % while upfront revascularization was performed in 45.2 % of cases. Excluding autoptic studies, mortality rate was 4.1 %, without significant differences between pre and postpartum SCAD (p-value 0.6) or according to initial therapeutic approach (p-value 0.5). Recurrences after index event were registered in 74 patients (23.4 %), being more common after medical treatment than in case of immediate revascularization (30.8 versus 18.3 %, p-value 0.02).
Conclusions
P-SCAD is a complex clinical scenario: timely diagnosis is difficult, therapeutic management not well-defined, rate of recurrences not negligible. Additional observational studies and dedicated registries are necessary to enhance the management of this rare but severe condition.
{"title":"Unveiling an insidious diagnosis and its implications for clinical practice: Individual patient data systematic review of pregnancy-associated spontaneous coronary artery dissection","authors":"","doi":"10.1016/j.ijcard.2024.132582","DOIUrl":"10.1016/j.ijcard.2024.132582","url":null,"abstract":"<div><h3>Background</h3><div>Pregnancy-Associated Spontaneous Coronary Artery Dissection (P-SCAD) is the most common cause of myocardial infarction in pregnancy and postpartum. Aim of this systematic review is to provide a descriptive picture of P-SCAD presentation, clinical course, management and outcomes.</div></div><div><h3>Methods</h3><div>International databases were systematically screened up to November 2023 and all published P-SCAD case reports/series identified; additionally, we gathered four original cases, establishing a new database for the derived cohort.</div></div><div><h3>Results</h3><div>253 studies (215 case reports, 38 case series) were included for the analysis, enrolling 316 patients admitted between 1952 and 2023. Median age was 34 (SD 5) years old, 64 (20.4 %) were prepartum, 249 (79.6 %) postpartum. Most common presentation was ST-elevation myocardial infarction (72.6 %). Cardiac arrest and cardiogenic shock occurred in 18.4 % and 16.1 %, respectively. Multivessel dissection was present in 45.2 % of cases, with left anterior descending artery being most frequently affected (74.4 %). Initial therapeutic strategy was medical therapy in 54.8 % while upfront revascularization was performed in 45.2 % of cases. Excluding autoptic studies, mortality rate was 4.1 %, without significant differences between pre and postpartum SCAD (<em>p</em>-value 0.6) or according to initial therapeutic approach (p-value 0.5). Recurrences after index event were registered in 74 patients (23.4 %), being more common after medical treatment than in case of immediate revascularization (30.8 versus 18.3 %, <em>p</em>-value 0.02).</div></div><div><h3>Conclusions</h3><div>P-SCAD is a complex clinical scenario: timely diagnosis is difficult, therapeutic management not well-defined, rate of recurrences not negligible. Additional observational studies and dedicated registries are necessary to enhance the management of this rare but severe condition.</div></div>","PeriodicalId":13710,"journal":{"name":"International journal of cardiology","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142307707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-21DOI: 10.1016/j.ijcard.2024.132591
Objective
YouTube®, attracts billions of monthly viewers, including those seeking health-related content. However, the quality standards of information are highly variable. The study aimed to evaluate the educational merit of YouTube® concerning pacemakers, focusing on quality and reliability for educating both patients and physicians.
Methods
The term “pacemaker” was searched on YouTube®. Following the application of exclusion criteria based on video language, duration, and minimum view count, a total of 71 videos were analyzed. Quality was assessed using the Global Quality Score (GQS), while reliability was evaluated using the modified DISCERN (mDISCERN) score. Data and metrics available regarding the channel and the specific video were obtained. The Kolmogorov–Smirnov test was employed to assess data normality, and the Mann-Whitney U test was utilized to determine statistical significance.
Results
Youtube videos on cardiac pacemakers proved to be of moderate quality, with an average GQS score of 3.10, and of moderate reliability, indicated by a mean mDISCERN score of 3.08. Higher scores were reported for videos of more than five minute duration, the ones that were targeted at physicians, and the videos with higher view ratios. The presence of a board-certified MD yielded statistically greater mean GQS, but not mDISCERN score. No statistical difference was observed based on the number of likes.
Conclusion
In conclusion, while YouTube® offers significant education opportunities, there is a clear need for enhanced oversight and quality control. Healthcare providers should guide patients towards valid resources and consider collaborating with platforms to develop content standards.
{"title":"Trusting the tube? YouTube®’s role in pacemaker patient and physician education","authors":"","doi":"10.1016/j.ijcard.2024.132591","DOIUrl":"10.1016/j.ijcard.2024.132591","url":null,"abstract":"<div><h3>Objective</h3><div>YouTube®, attracts billions of monthly viewers, including those seeking health-related content. However, the quality standards of information are highly variable. The study aimed to evaluate the educational merit of YouTube® concerning pacemakers, focusing on quality and reliability for educating both patients and physicians.</div></div><div><h3>Methods</h3><div>The term “pacemaker” was searched on YouTube®. Following the application of exclusion criteria based on video language, duration, and minimum view count, a total of 71 videos were analyzed. Quality was assessed using the Global Quality Score (GQS), while reliability was evaluated using the modified DISCERN (mDISCERN) score. Data and metrics available regarding the channel and the specific video were obtained. The Kolmogorov–Smirnov test was employed to assess data normality, and the Mann-Whitney <em>U</em> test was utilized to determine statistical significance.</div></div><div><h3>Results</h3><div>Youtube videos on cardiac pacemakers proved to be of moderate quality, with an average GQS score of 3.10, and of moderate reliability, indicated by a mean mDISCERN score of 3.08. Higher scores were reported for videos of more than five minute duration, the ones that were targeted at physicians, and the videos with higher view ratios. The presence of a board-certified MD yielded statistically greater mean GQS, but not mDISCERN score. No statistical difference was observed based on the number of likes.</div></div><div><h3>Conclusion</h3><div>In conclusion, while YouTube® offers significant education opportunities, there is a clear need for enhanced oversight and quality control. Healthcare providers should guide patients towards valid resources and consider collaborating with platforms to develop content standards.</div></div>","PeriodicalId":13710,"journal":{"name":"International journal of cardiology","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142307706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-21DOI: 10.1016/j.ijcard.2024.132575
Amani Khalouf, A Sami Abuzaid, Ahmed Altibi
{"title":"Editorial: Unveiling the clinical implications of left atrial remodeling assessment methods.","authors":"Amani Khalouf, A Sami Abuzaid, Ahmed Altibi","doi":"10.1016/j.ijcard.2024.132575","DOIUrl":"https://doi.org/10.1016/j.ijcard.2024.132575","url":null,"abstract":"","PeriodicalId":13710,"journal":{"name":"International journal of cardiology","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142307705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-20DOI: 10.1016/j.ijcard.2024.132585
{"title":"An in-depth look at electrolytes in acute heart failure: The role of sodium-to-chloride ratio.","authors":"","doi":"10.1016/j.ijcard.2024.132585","DOIUrl":"10.1016/j.ijcard.2024.132585","url":null,"abstract":"","PeriodicalId":13710,"journal":{"name":"International journal of cardiology","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142286293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-20DOI: 10.1016/j.ijcard.2024.132590
Aman Goyal, Muhammad Daoud Tariq, Syeda Shahnoor, Humza Saeed, Abdul Moiz Khan, Samia Aziz Sulaiman, Hritvik Jain, Rozi Khan, Wael AlJaroudi
Background: Chronic Total Occlusion (CTO) involves severe coronary artery blockage that impairs blood flow and affects 15-20 % of patients undergoing coronary angiography and over 40 % with diabetes or heart failure. Percutaneous Coronary Intervention (PCI) is used to restore blood flow in such cases. The retrograde approach, developed due to lower success with the antegrade method in complex cases, improves outcomes but increases complications. This meta-analysis compares the efficacy and safety of both approaches to guide clinical practice.
Methods: A comprehensive literature search was conducted on PubMed, Embase, Google Scholar, and Scopus until June 5, 2024, to find studies comparing antegrade and retrograde approaches in CTO-PCI patients. Pooled risk ratios (RR) with 95 % confidence intervals (CI) were calculated using R software (version 4.4.1), with significance set at p < 0.05. Random-effects models were used for all analyses.
Results: Our analysis included 22 observational studies with 49,152 CTO-PCI patients: 35,844 in the antegrade arm and 13,308 in the retrograde arm. The antegrade approach showed significantly lower risks of in-hospital outcomes, including mortality [RR: 0.45; p < 0.001], myocardial infarction [RR: 0.37; p < 0.001], major adverse cardiovascular events [RR: 0.34; p < 0.001], and cerebrovascular events [RR: 0.50; p = 0.011]. Long-term outcomes, such as all-cause mortality [RR: 0.71; p = 0.157] and myocardial infarction [RR: 0.76; p = 0.438], were comparable between both approaches.
Conclusion: The antegrade technique shows better outcomes and procedural advantages over retrograde revascularization, though long-term outcomes are similar. Further studies, especially randomized controlled trials are needed to confirm these findings.
{"title":"Short- and long-term outcomes of antegrade versus retrograde approaches in patients undergoing percutaneous coronary intervention for chronic total occlusion: A meta-analysis.","authors":"Aman Goyal, Muhammad Daoud Tariq, Syeda Shahnoor, Humza Saeed, Abdul Moiz Khan, Samia Aziz Sulaiman, Hritvik Jain, Rozi Khan, Wael AlJaroudi","doi":"10.1016/j.ijcard.2024.132590","DOIUrl":"https://doi.org/10.1016/j.ijcard.2024.132590","url":null,"abstract":"<p><strong>Background: </strong>Chronic Total Occlusion (CTO) involves severe coronary artery blockage that impairs blood flow and affects 15-20 % of patients undergoing coronary angiography and over 40 % with diabetes or heart failure. Percutaneous Coronary Intervention (PCI) is used to restore blood flow in such cases. The retrograde approach, developed due to lower success with the antegrade method in complex cases, improves outcomes but increases complications. This meta-analysis compares the efficacy and safety of both approaches to guide clinical practice.</p><p><strong>Methods: </strong>A comprehensive literature search was conducted on PubMed, Embase, Google Scholar, and Scopus until June 5, 2024, to find studies comparing antegrade and retrograde approaches in CTO-PCI patients. Pooled risk ratios (RR) with 95 % confidence intervals (CI) were calculated using R software (version 4.4.1), with significance set at p < 0.05. Random-effects models were used for all analyses.</p><p><strong>Results: </strong>Our analysis included 22 observational studies with 49,152 CTO-PCI patients: 35,844 in the antegrade arm and 13,308 in the retrograde arm. The antegrade approach showed significantly lower risks of in-hospital outcomes, including mortality [RR: 0.45; p < 0.001], myocardial infarction [RR: 0.37; p < 0.001], major adverse cardiovascular events [RR: 0.34; p < 0.001], and cerebrovascular events [RR: 0.50; p = 0.011]. Long-term outcomes, such as all-cause mortality [RR: 0.71; p = 0.157] and myocardial infarction [RR: 0.76; p = 0.438], were comparable between both approaches.</p><p><strong>Conclusion: </strong>The antegrade technique shows better outcomes and procedural advantages over retrograde revascularization, though long-term outcomes are similar. Further studies, especially randomized controlled trials are needed to confirm these findings.</p>","PeriodicalId":13710,"journal":{"name":"International journal of cardiology","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142286236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-20DOI: 10.1016/j.ijcard.2024.132584
Roberto G Carbone, Anne Marie Russell
{"title":"Smoking cessation in heart and chronic respiratory disease: A healthy global strategy.","authors":"Roberto G Carbone, Anne Marie Russell","doi":"10.1016/j.ijcard.2024.132584","DOIUrl":"https://doi.org/10.1016/j.ijcard.2024.132584","url":null,"abstract":"","PeriodicalId":13710,"journal":{"name":"International journal of cardiology","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142286237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-19DOI: 10.1016/j.ijcard.2024.132570
{"title":"Exploring the role of anticoagulants in coronary artery ectasia: A path forward","authors":"","doi":"10.1016/j.ijcard.2024.132570","DOIUrl":"10.1016/j.ijcard.2024.132570","url":null,"abstract":"","PeriodicalId":13710,"journal":{"name":"International journal of cardiology","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142286253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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