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Effect of adding ozone sauna to local injections in low back pain treatment. 局部注射加臭氧桑拿治疗腰痛的疗效观察。
Pub Date : 2022-12-30 DOI: 10.7203/jo3t.6.7.2022.25989
T. Tanbouli
Purpose: To evaluate the effect of adding ozone sauna with local O3 injection in low back treatment and comparing it to local O3 injection alone. Patients & Methods: This study was conducted on 70 patients suffering from chronic low back pain (
目的:评价臭氧桑拿加局部注射O3在腰背部治疗中的效果,并与单纯局部注射O3进行比较。患者与方法:本研究对70例慢性腰痛患者(
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引用次数: 0
Ozone therapy in the treatment of covid 19 infection and our clinical experience. 臭氧疗法治疗covid - 19感染的临床经验。
Pub Date : 2022-12-30 DOI: 10.7203/jo3t.6.7.2022.25986
Lale Yeprem
Covid 19, which was diagnosed for the first time in Wuhan, China turned into a pandemic that affected the whole world, 265 million people were infected and 5 million 300 thousand people died, according to the December 2021 data. While researchers investigate effective treatment methods for Covid19 Virus, vaccine studies are carried out to control the corona epidemical all over the World. Considering the effects of ozone therapy on the immune system based on the clinical studies, the treatment protocols for Covid 19 were created in the early stages of the pandemic. The purpose of this study was to investigate the effectiveness of ozone therapy in early and late stages of the Covid 19 infection in hospitalized patients in the State Hospital-Istanbul. 1st episode April-June 2020, 2nd episode September-December 2020, and 3rd episode March 2021-March 2022. In the 1st episode the hospitalization criteria was different, we hospitalized 80 patients in early stage, the 2d and 3rd episodes hospitalization criteria changed and we hospitalized 353 patients but due to the criteria the hospitalization was later so the results changed accordingly. We used Rectal Insufflations of 450 ml ozone Oxygen gas mixture 30 mcgr/ml daily for 5 days. We have concluded that early hospitalization and early ozonization decrease the duration of hospitalization and mortality.
根据2021年12月的数据,在中国武汉首次确诊的新冠肺炎成为影响全球的大流行,共有2.65亿人感染,530万人死亡。在研究人员研究covid - 19病毒有效治疗方法的同时,正在进行疫苗研究,以控制世界各地的冠状病毒流行。根据临床研究,考虑到臭氧治疗对免疫系统的影响,在新冠肺炎大流行初期制定了治疗方案。本研究的目的是探讨臭氧治疗在伊斯坦布尔国立医院住院患者Covid - 19感染的早期和晚期的有效性。第一集2020年4月至6月,第二集2020年9月至12月,第三集2021年3月至2022年3月。第一次发作的住院标准不同,早期住院80例,第二次和第三次发作的住院标准改变,住院353例,但由于住院标准较晚,因此结果也发生了变化。我们使用直肠灌注450 ml臭氧氧混合气体30 mcgr/ml,每天5天。我们的结论是,早期住院和早期臭氧化可以减少住院时间和死亡率。
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引用次数: 0
Ozone applications in veterinary ophtalmology. 臭氧在兽医眼科中的应用。
Pub Date : 2022-12-30 DOI: 10.7203/jo3t.6.7.2022.25997
Eduardo Colin-Flores
PURPOSE. To evaluate the clinical improvement of 4 patients diagnosed with ophtalmic patologies treated with ozone therapy under adjusted protocols for each patient. CASE PRESENTATION. Four patients were presented to veterinary consultation for the diagnose of different injuries using biopsy, blood examination and fluorescein in some cases. According to the diagnose (a mare with equine recurrent uveitis (ERU), a gelding with squamous cell carcinoma (SCC), a colt with light corneal ulceration, a mare with a fusiform cell sarcoma and a filly with corneal ulceration and eyelid laceration. The ozone protocol was established using combinations of local infiltration, topic instillation of ozonized oil, topic instillation of ozonized injectable distilled water, ozonized autologous serum, major and minor autohemotherapy. The results showed an improvement of general state of the patients, complete disappearance of ERU in patient 1 and complete remission in patient 2 –SCC- after clinical monitoring of biannual control. In patient diagnosed with light corneal ulceration, the injury and edema completely disappeared. In patient 4, surgical excision was performed and subsequently ozone therapies were performed, non-recurrence of the lesion was achieved. Patient number 5 improved 100% 48 hours after the treatment. Evidence can be shown. DISCUSSION. Despite the fact that ophtalmological problems are delicate and the current pharmacology helps to solve them, it was shown that the results obtained with ozone therapy were overwhelming, there were no complications and there have been no recurrences in the problems that commonly occur with conventional treatments. CONCLUSION. Due to the results, it can be concluded that ozone therapy can be used to treat ophthalmic problems associated to different origins and that in cancer problems there are no recurrence of the pathology.
目的。评价4例经调整方案臭氧治疗的眼科病变患者的临床疗效。案例演示。4例患者接受兽医会诊,采用活检、血液检查和荧光素诊断不同的损伤。根据诊断(一匹母马复发性葡萄膜炎(ERU),一匹骟马患有鳞状细胞癌(SCC),一匹小马患有轻度角膜溃疡,一匹母马患有梭状细胞肉瘤,一匹母马患有角膜溃疡和眼睑撕裂。采用局部浸润、局部灌注臭氧油、局部灌注臭氧可注射蒸馏水、臭氧自体血清、大剂量和小剂量自体血液治疗相结合的方法建立臭氧治疗方案。结果显示患者一般状态改善,患者1的ERU完全消失,患者2 - scc -经半年对照临床监测后完全缓解。诊断为轻度角膜溃疡的患者,损伤和水肿完全消失。在患者4中,手术切除并随后进行臭氧治疗,病变未复发。5号病人治疗48小时后好转100%可以出示证据。讨论。尽管眼科问题是微妙的,目前的药理学有助于解决这些问题,但研究表明,臭氧治疗取得的结果是压倒性的,没有并发症,也没有常规治疗中常见的问题复发。结论。结果表明,臭氧治疗可用于治疗不同来源的眼科问题,并且在癌症问题中不会复发。
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引用次数: 0
VII Congress of the WFOT 世贸组织第七届代表大会
Pub Date : 2022-12-30 DOI: 10.7203/jo3t.6.7.2022.26226
S. Tiron
Dear friends, I wholeheartedly welcome you all to the 7th WORLD OZONE THERAPY FEDERATION CONGRESS, hosted between 5th – 7th of May in Bucharest, Romania. We are pleased to welcome a large number of participants from 25 countries despite the global challenges that are we all faced with (the on-going Covid pandemic and war in Ukraine). On this occasion, I wish to send our thoughts of support and compassion to our colleagues in Ukraine, who are currently facing the atrocities of war and humanitarian crisis. The conditions for practicing ozone therapy are still quite difficult due to the opposition of medical officials from various countries. Thus, it is essential that we continue our efforts to develop scientific papers that support the benefits of the ozone therapy. I am sure that through our common efforts we are one step closer to scientific acknowledgment and acceptance.
亲爱的朋友们,我衷心欢迎大家参加5月5日至7日在罗马尼亚布加勒斯特举行的第七届世界臭氧治疗联合会大会。我们很高兴欢迎来自25个国家的众多与会者,尽管我们都面临着全球性挑战(正在进行的新冠肺炎大流行和乌克兰战争)。值此机会,我谨向目前正面临战争暴行和人道主义危机的乌克兰同事致以我们的支持和同情。由于各国医疗官员的反对,实施臭氧疗法的条件仍然相当困难。因此,我们必须继续努力,撰写支持臭氧疗法益处的科学论文。我相信,通过我们的共同努力,我们离科学承认和接受又近了一步。
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引用次数: 0
Immunity prophylaxis with ozone therapy – review report. 臭氧疗法预防免疫-综述报告。
Pub Date : 2022-12-30 DOI: 10.7203/jo3t.6.7.2022.25995
Milli Shah
Background: The prevalence of COVID-19 according to WHO on date July 09, 2020 was 205,128 confirmed cases in India with 35,362 of daily increase in positive cases. Immunity Prophylaxis is a project which was started at one of the essential water service company Bisleri International Pvt. Ltd. where activity of building immunity for essential workers and staff was initiated after outbreak of COVID 19.Immunity prophylaxis protocol was designed based on the scientific rational where use of Ozone therapy and correction of vitamin status. Material and methods: Employees of both genders, working in all departments of Bisleri Factory and office were recruited for the study, out of 440, 320 employees got registered to Immunity Prophylaxis protocol.The protocol was 8 sessions of minor autohaemotherapy of ozone therapy along with 2 sessions Vitamin D3 and Vitamin B12 intramuscular injections. We conducted a retrospective cohort study to compare the incidence of COVID-19 in essential workers in the period of July-August of 2020. Results: The present study, it was evident that out of 320 participants opting to Immunity prophylaxis protocol only 7 participants turned out positive to COVID-19 test which is 2.19 % of total population under study, there was significant decrease in rate of incidence of COVID 19 after treatment of Immunity prophylaxis protocol compared to incidence from community which suggest that Ozone treatment may have its role in prevention from COVID-19.
背景:根据世卫组织的数据,截至2020年7月9日,印度COVID-19的流行率为205,128例确诊病例,阳性病例每天增加35362例。免疫预防是一个在基本供水公司Bisleri International pto . Ltd.之一启动的项目,该公司在2019冠状病毒病爆发后启动了为基本工人和工作人员建立免疫力的活动。免疫预防方案是在科学合理的基础上设计的,其中使用臭氧疗法和纠正维生素状态。材料和方法:研究招募了Bisleri工厂和办公室各部门的男女员工,在440名员工中,有320名员工注册了免疫预防方案。治疗方案为8个疗程的少量自身血液治疗或臭氧治疗,同时2个疗程的肌肉注射维生素D3和维生素B12。我们开展回顾性队列研究,比较2020年7 - 8月基层工作人员COVID-19的发病率。结果:本研究发现,在选择免疫预防方案的320名参与者中,只有7名参与者的COVID-19检测呈阳性,占研究总人数的2.19%,免疫预防方案治疗后的COVID-19发病率与社区发病率相比显着降低,提示臭氧治疗可能在预防COVID-19方面发挥作用。
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引用次数: 1
Back pain “not just herniated disc”: results of treatment with oxygen-ozone therapy in selected applications. 背部疼痛“不只是椎间盘突出”:氧臭氧治疗的结果在选定的应用程序。
Pub Date : 2022-12-30 DOI: 10.7203/jo3t.6.7.2022.25976
M. Bonetti
Low back pain and lumbosciatica are highly disabling pathologies, more and more widespread in every social category and manifest themselves at an increasingly precocious age. They can be supported by numerous different vertebral pathologies, often concomitant: diseases of the disc, of the facet joints, spondylolysis (with or without listesis), somatic and interapophyseal arthrosis, stenosis of the vertebral canal, radicular and synovial cysts, meningiomas, primary or metastatic neoplastic pathology etc. In order to choose the best therapy, in cases of low back pain and / or sciatica pain, a precise diagnosis made after a careful objective examination and supported by suitable instrumental examinations is therefore essential. In particular, in addition to standard radiograms of the spine, in these patients the Computed Tomography and / or Magnetic Resonance Imaging is essential. In recent years, several studies have demonstrated the utility of oxygen-ozone therapy in the treatment of herniated discs with the result of herniated discs reduced in size. In this study the authors evaluated the therapeutic results obtained in the treatment with oxygen-ozone therapy of 416 patients suffering from non-discogenic low back pain caused by pathology of the posterior vertebral compartment (facet synovitis, Baastrup syndrome, spondylolysis and spondylolisthesis, facet degeneration).
腰痛和腰痛是高度致残的疾病,在社会的各个类别中越来越普遍,并且在越来越早的年龄中表现出来。它们可以由许多不同的椎体病理支持,通常伴随:椎间盘疾病、小关节、峡部裂(伴或不伴滑脱)、躯体和椎间关节、椎管狭窄、神经根和滑膜囊肿、脑膜瘤、原发性或转移性肿瘤病理等。为了选择最好的治疗方法,对于腰痛和/或坐骨神经痛的病例,在仔细客观检查后做出准确的诊断,并辅以适当的器械检查是必不可少的。特别是,除了标准的脊柱x线照片外,这些患者的计算机断层扫描和/或磁共振成像是必不可少的。近年来,一些研究已经证明了氧臭氧疗法在椎间盘突出治疗中的效用,其结果是椎间盘突出缩小。在这项研究中,作者评估了416例由后椎间室病理(小关节滑膜炎、Baastrup综合征、峡部裂和峡部滑脱、小关节退变)引起的非椎间盘源性腰痛患者的氧臭氧治疗结果。
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引用次数: 0
Ozone therapy in chronic viral hepatitis C in third age patients 臭氧治疗慢性丙型肝炎三岁患者
Pub Date : 2022-12-30 DOI: 10.7203/jo3t.6.7.2022.25982
N. Bodrug
Chronic viral hepatitis C (HCV) is a global medical problem, its prevalence increases with age and involves high morbidity and mortality in the elderly population. The disease progresses slowly and is detected, accidentally, leading to devitalization of the body and it’s difficult to treat. In most cases, hepatitis C leads to complications such as cirrhosis (20-25%), ascites, liver carcinoma (5%), hepatocellular failure. The usual line of treatment is expensive, involves major side effects and low efficiency, high number of comorbidities, polypragmatism makes the difference for the elderly with the need to individualize treatment. Overlapping pathological changes with age-dependent ones determine the clinical picture with decreased physical activity and loss of functionality. The present study aimed to update HCV treatment regimens in the elderly by including ozone therapy, evaluating clinical, para clinical and functional efficacy.
慢性病毒性丙型肝炎(HCV)是一个全球性的医学问题,其患病率随着年龄的增长而增加,在老年人群中发病率和死亡率都很高。这种疾病进展缓慢,偶然被发现,导致身体失活,很难治疗。在大多数情况下,丙型肝炎会导致并发症,如肝硬化(20-25%)、腹水、肝癌(5%)、肝细胞衰竭。通常的治疗方法价格昂贵,副作用大,效率低,合并症多,多实用主义使得老年人需要个性化治疗。与年龄相关的重叠病理改变决定了身体活动减少和功能丧失的临床表现。本研究旨在更新老年人丙型肝炎治疗方案,包括臭氧治疗,评估临床、准临床和功能疗效。
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引用次数: 0
Ozonucleolysis in cervical radiculopathy – Pakistan experience. 颈椎神经根病的臭氧核溶解-巴基斯坦经验。
Pub Date : 2022-12-30 DOI: 10.7203/jo3t.6.7.2022.25977
U. Chaudhry
BACKGROUND AND PURPOSE Direct injection of Oxygen-Ozone in the cervical discs has proved to be the effective alternative to surgery in patients with cervical disc herniation in many countries around the world. We report our experience with ozonucleolysis with patients effected by pain incervical region (brachialgia)due to disc herniation including post-operative recurrence or disc prolapse. METHODS 6000 patients were treated with single session of Oxygen-Ozone therapy from 2005-2020. All the patients had CT or MRI evidence of cervical disc prolapse with clinical signs of cervical nerve root compression. The procedure was performed under angiofluoroscopy using 22/23 G spinal needle without anesthesia. All the patients received intradiscal injection n of Oxygen-Ozone mixture at Ozone concentration of 30 µgm/ml. Among these patients 4500 were males and 1500 were females between the ages of 20-70 years. Therapeutic outcome was assessed 8 week after treatment by using modified MacNab method. RESULTS A satisfactory therapeutic outcome was obtained. 60% of the patients showed complete recovery with resolution of symptoms. 20% of the patients complained of occasional episodic neck pain and arms pain with no limitation of occupational activity. 5% of cases showed some improvement. 5% of cases had insufficient or noimprovement and went for surgery. 10% of cases never turned up after the first visit. CONCLUSION Intradiscal injection of Ozone for herniated cervical disc has revolutionized percutaneous approach to nerve root diseases making it safer, cheaper and easier to repeat than treatments currently in use.
背景与目的在颈椎间盘内直接注射氧-臭氧已被世界上许多国家证明是治疗颈椎间盘突出症的有效替代方法。我们报告我们的经验,与患者的影响,颈部疼痛(臂痛)由于椎间盘突出,包括术后复发或椎间盘脱垂。方法2005-2020年对6000例患者进行单次氧-臭氧治疗。所有患者均有颈椎间盘突出的CT或MRI证据,临床表现为颈神经根受压。手术在血管透视下进行,使用22/ 23g脊髓针,无麻醉。所有患者均接受臭氧浓度为30µgm/ml的氧-臭氧混合液椎间盘内注射。其中男性4500例,女性1500例,年龄在20-70岁之间。治疗后8周采用改良MacNab法评价治疗效果。结果获得满意的治疗效果。60%的患者完全康复,症状缓解。20%的患者抱怨偶尔发作性颈部疼痛和手臂疼痛,没有限制职业活动。5%的病例有所改善。5%的病例没有改善或改善不足而去做手术。10%的病例在第一次就诊后就再也没有出现。结论椎间盘内注射臭氧治疗颈椎间盘突出症,使经皮治疗神经根疾病的方法发生了革命性的变化,比目前使用的治疗方法更安全、更便宜、更容易重复。
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引用次数: 0
Comparative analysis of 2 groups of people according to age and sex, vaccinated triple versus covid-19, were subjected to quantitative analysis of antibodies and B lymphocytes after ozone therapy. 对比分析两组按年龄和性别接种三联抗covid-19疫苗的人,臭氧治疗后进行抗体和B淋巴细胞的定量分析。
Pub Date : 2022-12-30 DOI: 10.7203/jo3t.6.7.2022.25981
Jose German Medina
This is a retrospective work that analyzes the behavior of two groups of people of different sex who received triple doses of Vaccine Anti Covid19, being object one of those two groups of application of Ozone therapy via blood (AHTMy and IR), and blood samples were taken, after these cycles of ozone application, and the titles of IgG antibodies and level of B lymphocytes were quantified by the immunofluorescence method. Both groups were analyzed by covid19 test, observing that in the group that received Ozone Therapy did not develop disease and the numbers of antibody titles and B lymphocytes were much higher than the group (also being triple vaccinated) that did not receive Ozone Therapy and which in its 98% developed disease at the time of transmission of Omicron.
本研究是回顾性分析两组不同性别的人接受三剂抗新冠病毒疫苗的行为,作为两组血液应用臭氧治疗(AHTMy和IR)的对象之一,并在这些臭氧应用周期后采集血液样本,用免疫荧光法定量IgG抗体和B淋巴细胞水平。通过covid - 19测试对两组进行分析,观察到接受臭氧治疗的组未发生疾病,抗体名称和B淋巴细胞的数量远高于未接受臭氧治疗的组(也接种了三次疫苗),其中98%的人在传播Omicron时发生疾病。
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引用次数: 1
Therapeutic effect and safety of ozone therapy in sars cov-2 patients. Cuban experience 臭氧治疗sars - cov-2患者的疗效及安全性。古巴的经验
Pub Date : 2022-12-30 DOI: 10.7203/jo3t.6.7.2022.25980
Silvia Menéndez-Cepero
SARS-Cov2, the virus causing COVID-19, is distributed globally since December 2019, classified as a pandemic by the World Health Organization. The virus is known to cause Acute Respiratory Distress Syndrome (ARDS). Cytokine storm is considered to be one of the major causes of ARDS and multiple-organ failure. Due to the high lethality of SARS-CoV2 infections and its economic and social impact, it is necessary to seek new therapeutic procedures. It has been demonstrated that ozone therapy produces a significant improvement in blood flow and oxygenation of ischemic tissues. Also, ozone can achieve an equilibrium between Nrf2 and NF-?B factors, modulating oxidative stress and the expression of pro-inflammatory cytokines. Levels of reduced glutathione (GSH), the key antioxidant guardian in all tissues, could be critical in extinguishing the exacerbated inflammation that triggers organ failure in COVID-19. The reduced levels of GSH are clinically associated with severe disease. It is well documented that ozone activates the level of GSH. In clinical studies, ozone has a significant role in the treatment of pulmonary and vascular diseases. An exploratory, controlled, open and monocentric study was carried out in 32 patients with mild to moderate symptoms, distributed at random in two groups of 16 patients each. The first group received rectal ozone therapy (ozone concentration between 25 and 40 mg/L and volume between 100 and 200 ml, twice per day) together with conventional treatment with Kaletra Lopinavir/Ritonavir), chloroquine and/or Heberferon®, and the second group only conventional treatment. The result of the RT-PCR and the evolution of the clinical signs were the primary efficacy variables. Secondary efficacy variables were ferritin, C-reactive protein, oxidative stress biomarkers, cellular indicators of inflammation, biochemical and hematological variables, and the presence of adverse effects. Patients (81%) who received rectal ozone therapy had a negative RT-PCR after the tenth ozone therapy application (after 5 days), with significant differences from the control group at the same time. In all patients, improvements in the levels of C-reactive protein and cellular indicators of inflammation were achieved at the end of the treatment. Ozone treatment significantly increases GSH levels compared to the control group, but not other REDOX markers. The treatments were safe and welltolerated. Also, a pilot, open-label, phase IV clinical trial study was performed in 40 SARS-CoV-2 convalescent patients (with symptoms extending beyond three weeks since negative PCR test) distributed at random into 2 groups. One group was treated with BIOPLA (dietary complement based on a concentrated protein - mineral elaborated from human placental after born, 1 capsule of 400 mg during 30 days) and the ozone group treated with rectal ozone application (ozone concentration between 20 and 35 mg/L and volume between 150 and 200 ml, 20 sessions, one per day) + BIOPLA. B
导致COVID-19的病毒SARS-Cov2自2019年12月以来在全球分布,被世界卫生组织列为大流行。这种病毒已知会引起急性呼吸窘迫综合征(ARDS)。细胞因子风暴被认为是ARDS和多器官功能衰竭的主要原因之一。由于SARS-CoV2感染的高致死率及其经济和社会影响,有必要寻求新的治疗方法。已经证明,臭氧疗法可以显著改善缺血组织的血流和氧合。此外,臭氧可以在Nrf2和NF-?B因子,调节氧化应激和促炎细胞因子的表达。还原型谷胱甘肽(GSH)是所有组织中关键的抗氧化守护者,它的水平可能对消除加剧的炎症至关重要,而炎症会引发COVID-19中的器官衰竭。谷胱甘肽水平降低在临床上与严重疾病有关。有充分的证据表明,臭氧会激活谷胱甘肽的水平。在临床研究中,臭氧在肺部和血管疾病的治疗中具有重要作用。对32例轻中度症状患者进行探索性、对照性、开放性、单中心研究,随机分为两组,每组16例。第一组患者接受直肠臭氧治疗(臭氧浓度在25 - 40mg /L之间,体积在100 - 200ml之间,每天2次),同时使用卡乐特拉洛匹那韦/利托那韦、氯喹和/或Heberferon®进行常规治疗,第二组仅进行常规治疗。RT-PCR结果及临床体征演变为主要疗效指标。次要疗效变量为铁蛋白、c反应蛋白、氧化应激生物标志物、炎症细胞指标、生化和血液学变量以及是否存在不良反应。接受直肠臭氧治疗的患者(81%)在第10次臭氧治疗后(5天后)RT-PCR为阴性,与对照组同期差异有统计学意义。在所有患者中,c反应蛋白水平和炎症细胞指标在治疗结束时均有所改善。与对照组相比,臭氧处理显著增加谷胱甘肽水平,但没有其他氧化还原标志物。这些治疗是安全且耐受性良好的。此外,在40名SARS-CoV-2恢复期患者(自PCR阴性检测后症状持续超过三周)中进行了一项开放标签的试验性四期临床试验研究,随机分为两组。一组使用BIOPLA(以出生后从人胎盘中提取的浓缩蛋白质-矿物质为基础的膳食补剂,30天内1粒400 mg),臭氧组使用直肠臭氧(臭氧浓度在20 - 35 mg/L之间,体积在150 - 200 ml之间,20次,每天1次)+ BIOPLA。两组均接受治疗并随访1个月。20名被认为健康的人被纳入并作为对照组进行评估。效果评估显示,两个治疗组均有有益改善,85%的患者接受BIOPLA + RIO3T治疗,37%的患者接受BIOPLA治疗
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引用次数: 0
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Journal of Ozone Therapy
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