Pub Date : 2023-04-01DOI: 10.22271/oral.2023.v9.i2g.1773
D. Hs, D. N, D. B. Brigit, Dr. Annie Swathisha P, Dr. Shylaja V
The interaction between stem cells and growth factors plays a major role in the regeneration of the pulp-dentin complex. Studies have reported the potential role of Bone Morphogenic Proteins (BMPs) in the growth and differentiation of cells. The purpose of the present systematic review was to analyze the role of Bone Morphogenic Protein-2 (BMP-2) in the osteogenic/odontogenic differentiation of Stem cells from apical papilla (SCAP). The search was conducted across PubMed, Science Direct, Cochrane Library, and Google Scholar. In-vivo and in-vitro studies published between 2000 and 2022 were evaluated for the outcome. The quality assessment of the studies was done using the QUIN assessment tool. After applying the keywords, and filters along with inclusion & exclusion criteria, a total of six articles were selected for the present systematic review, all of which were in-vitro studies. The studies reported that BMP-2 significantly enhanced the osteogenic/odontogenic potential of SCAP cells. Moreover, BMP-2 could act synergistically with various other factors to bring about the desired effect. Being a potential growth factor in the regeneration of the pulp-dentin complex, the application of BMP-2 can be extended to the clinical scenario for various cell-free and cell-based regenerative approaches.
{"title":"Bone Morphogenic protein-2 in the osteogenic/odontogenic differentiation of stem cells from apical papilla: A systematic review","authors":"D. Hs, D. N, D. B. Brigit, Dr. Annie Swathisha P, Dr. Shylaja V","doi":"10.22271/oral.2023.v9.i2g.1773","DOIUrl":"https://doi.org/10.22271/oral.2023.v9.i2g.1773","url":null,"abstract":"The interaction between stem cells and growth factors plays a major role in the regeneration of the pulp-dentin complex. Studies have reported the potential role of Bone Morphogenic Proteins (BMPs) in the growth and differentiation of cells. The purpose of the present systematic review was to analyze the role of Bone Morphogenic Protein-2 (BMP-2) in the osteogenic/odontogenic differentiation of Stem cells from apical papilla (SCAP). The search was conducted across PubMed, Science Direct, Cochrane Library, and Google Scholar. In-vivo and in-vitro studies published between 2000 and 2022 were evaluated for the outcome. The quality assessment of the studies was done using the QUIN assessment tool. After applying the keywords, and filters along with inclusion & exclusion criteria, a total of six articles were selected for the present systematic review, all of which were in-vitro studies. The studies reported that BMP-2 significantly enhanced the osteogenic/odontogenic potential of SCAP cells. Moreover, BMP-2 could act synergistically with various other factors to bring about the desired effect. Being a potential growth factor in the regeneration of the pulp-dentin complex, the application of BMP-2 can be extended to the clinical scenario for various cell-free and cell-based regenerative approaches.","PeriodicalId":13838,"journal":{"name":"International Journal of Applied Dental Sciences","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77840141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-01DOI: 10.22271/oral.2023.v9.i2f.1760
Rucha Pandya, Monipriya Kongkham, Neema Shetty, A. Mathur, Ashish Bali, P. Pal
{"title":"Efficacy of indigenously prepared 10% piper betel gel in pain reduction during periodontal probing: A split mouth study","authors":"Rucha Pandya, Monipriya Kongkham, Neema Shetty, A. Mathur, Ashish Bali, P. Pal","doi":"10.22271/oral.2023.v9.i2f.1760","DOIUrl":"https://doi.org/10.22271/oral.2023.v9.i2f.1760","url":null,"abstract":"","PeriodicalId":13838,"journal":{"name":"International Journal of Applied Dental Sciences","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86886819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-01DOI: 10.22271/oral.2023.v9.i2b.1722
Dr. Pooja Bhanushali, Dr. Neema Shetty, Dr. Aditi Mathur, Dr. Ashish Bali, Dr. Pritish Pal, Dr. Krishna Agarwala
{"title":"Comparative evaluation of 4% mangosteen mouthwash with 0.2% chlorhexidine mouthwash as an adjunct to SRP in patients with gingivitis","authors":"Dr. Pooja Bhanushali, Dr. Neema Shetty, Dr. Aditi Mathur, Dr. Ashish Bali, Dr. Pritish Pal, Dr. Krishna Agarwala","doi":"10.22271/oral.2023.v9.i2b.1722","DOIUrl":"https://doi.org/10.22271/oral.2023.v9.i2b.1722","url":null,"abstract":"","PeriodicalId":13838,"journal":{"name":"International Journal of Applied Dental Sciences","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84746032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-01DOI: 10.22271/oral.2023.v9.i2f.1763
Dr. Ritu Mandhotra, Dinesh Rao, Dr. Sunil Panwar, Dr. Krittika Samaddar, D. Rv
{"title":"Correction of anterior malocclusion related to mesiodens: A case report","authors":"Dr. Ritu Mandhotra, Dinesh Rao, Dr. Sunil Panwar, Dr. Krittika Samaddar, D. Rv","doi":"10.22271/oral.2023.v9.i2f.1763","DOIUrl":"https://doi.org/10.22271/oral.2023.v9.i2f.1763","url":null,"abstract":"","PeriodicalId":13838,"journal":{"name":"International Journal of Applied Dental Sciences","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87659867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-01DOI: 10.22271/oral.2023.v9.i2f.1758
Dr. NK Sahoo, Dr. Shelly Sharma, Dr. Sahil Vashisht
{"title":"Unilateral case of class 3 kissing molars: A case report","authors":"Dr. NK Sahoo, Dr. Shelly Sharma, Dr. Sahil Vashisht","doi":"10.22271/oral.2023.v9.i2f.1758","DOIUrl":"https://doi.org/10.22271/oral.2023.v9.i2f.1758","url":null,"abstract":"","PeriodicalId":13838,"journal":{"name":"International Journal of Applied Dental Sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80792568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-01DOI: 10.22271/oral.2023.v9.i2b.1723
Dr. Mahalakshmi A
{"title":"Melatonin and Periodontal Disease: A Review","authors":"Dr. Mahalakshmi A","doi":"10.22271/oral.2023.v9.i2b.1723","DOIUrl":"https://doi.org/10.22271/oral.2023.v9.i2b.1723","url":null,"abstract":"","PeriodicalId":13838,"journal":{"name":"International Journal of Applied Dental Sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75865766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-01DOI: 10.22271/oral.2023.v9.i2a.1713
Dora María López Trujillo, Dr. María Fernanda Mendoza Durán, Juan Israel Alvarado Pérez, María de los Ángeles Pietschmann Santamaría, Lizeth Alvarado, Gilberto Zataraín Hernández, Martha Margarita Aguado Arzola
{"title":"In vitro analysis of antimicrobial activity in exposed collagen membranes applying chitosan-metronidazole in topical gel","authors":"Dora María López Trujillo, Dr. María Fernanda Mendoza Durán, Juan Israel Alvarado Pérez, María de los Ángeles Pietschmann Santamaría, Lizeth Alvarado, Gilberto Zataraín Hernández, Martha Margarita Aguado Arzola","doi":"10.22271/oral.2023.v9.i2a.1713","DOIUrl":"https://doi.org/10.22271/oral.2023.v9.i2a.1713","url":null,"abstract":"","PeriodicalId":13838,"journal":{"name":"International Journal of Applied Dental Sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88869065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-01DOI: 10.22271/oral.2023.v9.i2c.1729
Dr. Prakash Nidawani, Dr. Saumya Singh, Dr.S.Sesha Sai, Dr. Sufiya S, Dr. Girish Galagali
{"title":"An innovative facet in gender determination of regional population: A cross sectional study","authors":"Dr. Prakash Nidawani, Dr. Saumya Singh, Dr.S.Sesha Sai, Dr. Sufiya S, Dr. Girish Galagali","doi":"10.22271/oral.2023.v9.i2c.1729","DOIUrl":"https://doi.org/10.22271/oral.2023.v9.i2c.1729","url":null,"abstract":"","PeriodicalId":13838,"journal":{"name":"International Journal of Applied Dental Sciences","volume":"158 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84733636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-01DOI: 10.22271/oral.2023.v9.i2a.1706
Dr. Arya S Kumar, Dr. Kannan Vadakkepurayil, Dr. Harinee A, Dr. Umm Kulthum T, Dr. Shruti Sudarsanan
{"title":"Klippel-Feil Syndrome: Oral and maxillofacial rehabilitation: Rare case report","authors":"Dr. Arya S Kumar, Dr. Kannan Vadakkepurayil, Dr. Harinee A, Dr. Umm Kulthum T, Dr. Shruti Sudarsanan","doi":"10.22271/oral.2023.v9.i2a.1706","DOIUrl":"https://doi.org/10.22271/oral.2023.v9.i2a.1706","url":null,"abstract":"","PeriodicalId":13838,"journal":{"name":"International Journal of Applied Dental Sciences","volume":"51 4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82441166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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